Rima Kaddurah-Daouk

Rima Kaddurah-Daouk

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Rima Kaddurah-Daouk

Rima Kaddurah-Daouk

Publications by authors named "Rima Kaddurah-Daouk"

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Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology.

Alzheimers Dement (Amst) 2019 Dec 5;11:619-627. Epub 2019 Sep 5.

Department of Psychiatry and Behavioral Sciences, Department of Medicine and the Duke Institute for Brain Sciences, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1016/j.dadm.2019.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732667PMC
December 2019

Biobanking for Metabolomics and Lipidomics in Precision Medicine.

Clin Chem 2019 Jul 14;65(7):827-832. Epub 2019 May 14.

Director and Chair, National Metabolomics Core Facility, Technology Center, Institute for Molecular Medicine FIMM, HiLIFE, University of Helsinki, Finland.

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http://dx.doi.org/10.1373/clinchem.2018.298620DOI Listing
July 2019

Systematic Error Removal Using Random Forest for Normalizing Large-Scale Untargeted Lipidomics Data.

Anal Chem 2019 Mar 19;91(5):3590-3596. Epub 2019 Feb 19.

West Coast Metabolomics Center, UC Davis Genome Center , University of California, Davis , 451 Health Sciences Drive , Davis , California 95616 , United States.

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http://dx.doi.org/10.1021/acs.analchem.8b05592DOI Listing
March 2019

Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders.

Psychol Med 2019 Mar 14:1-12. Epub 2019 Mar 14.

NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction,Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo,Oslo,Norway.

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http://dx.doi.org/10.1017/S0033291719000400DOI Listing
March 2019

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers.

Alzheimers Dement 2019 Feb 15;15(2):232-244. Epub 2018 Oct 15.

Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA; Duke Institute of Brain Sciences, Duke University, Durham, NC, USA; Department of Medicine, Duke University, Durham, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454538PMC
February 2019

Generation and quality control of lipidomics data for the alzheimer's disease neuroimaging initiative cohort.

Sci Data 2018 11 20;5:180263. Epub 2018 Nov 20.

NIH-West Coast Metabolomics Center, University of California, Davis, 451 Health Sciences Drive, Davis, California 95616, United States.

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http://dx.doi.org/10.1038/sdata.2018.263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244184PMC
November 2018

Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression.

Biochem Pharmacol 2018 06 3;152:279-292. Epub 2018 Apr 3.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.03.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960634PMC
June 2018

The inhibition of the kynurenine pathway prevents behavioral disturbances and oxidative stress in the brain of adult rats subjected to an animal model of schizophrenia.

Prog Neuropsychopharmacol Biol Psychiatry 2018 Feb 13;81:55-63. Epub 2017 Oct 13.

Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina (UNESC), Criciúma, SC, Brazil; Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA; Laboratory of Experimental Microbiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina (UNESC), Criciúma, SC, Brazil.

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http://dx.doi.org/10.1016/j.pnpbp.2017.10.009DOI Listing
February 2018

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study.

PLoS Med 2018 01 25;15(1):e1002482. Epub 2018 Jan 25.

Clinical and Translational Neuroscience Unit, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784884PMC
January 2018

Ketamine potentiates oxidative stress and influences behavior and inflammation in response to lipolysaccharide (LPS) exposure in early life.

Neuroscience 2017 06 20;353:17-25. Epub 2017 Apr 20.

Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA; Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA; Laboratory of Experimental Microbiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina (UNESC), Criciúma, SC, Brazil.

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http://dx.doi.org/10.1016/j.neuroscience.2017.04.016DOI Listing
June 2017

Pharmacometabolomic signature links simvastatin therapy and insulin resistance.

Metabolomics 2017 01 23;13. Epub 2016 Dec 23.

Department of Internal Medicine; Department of Psychiatry and Behavioral Sciences, Duke Institute for Brain Sciences, Duke University Medical Center, Durham, NC, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931366PMC
January 2017

A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration.

Hypertension 2016 09 5;68(3):621-9. Epub 2016 Jul 5.

From the Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (M.H.S., Y.G., C.W.M., J.G.G., R.F.F., R.M.C.-D., J.A.J.) and Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine (T.J.G.), University of Florida, Gainesville; Department of Statistics, Bioinformatics Research Center, North Carolina State University, Raleigh (D.M.R., A.M.-R.); Department of Medicine, University of Maryland, Baltimore (A.L.B.); Department of Medicine, Emory University, Atlanta, GA (A.B.C.); Division of Nephrology and Hypertension, Department of Medicine, College of Medicine, Mayo Clinic, Rochester, MN (S.T.T.); Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, (E.B.); Department of Molecular and Cellular Biology and Genome Center, University of California, Davis (O.F.); and Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC (R.K.-D.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982802PMC
September 2016

Metabolomics enables precision medicine: "A White Paper, Community Perspective".

Metabolomics 2016;12(10):149. Epub 2016 Sep 2.

Psychiatry and Behavioral Sciences, Duke Internal Medicine and Duke Institute for Brain Sciences and Center for Applied Genomics and Precision Medicine, Duke University Medical Center, Box 3903, Durham, NC 27710 USA.

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http://dx.doi.org/10.1007/s11306-016-1094-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009152PMC
September 2016

Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach.

Metabolomics 2016 08 13;12(8). Epub 2016 Jul 13.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, PO Box 100486, Gainesville, FL 32610-0486, USA.

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http://dx.doi.org/10.1007/s11306-016-1076-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310671PMC
August 2016

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans.

Front Pharmacol 2016 14;7:135. Epub 2016 Jun 14.

Department of Psychiatry and Behavioral Sciences, Duke UniversityDurham, NC, USA; Duke Institute for Brain Sciences, Duke UniversityDurham, NC, USA.

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http://journal.frontiersin.org/Article/10.3389/fphar.2016.00
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http://dx.doi.org/10.3389/fphar.2016.00135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906013PMC
July 2016

Pharmacometabolomics informs Pharmacogenomics.

Metabolomics 2016 Jul 1;12(7). Epub 2016 Jul 1.

Department of Molecular Pharmacology and Experimental Therapeutics, 200 First Street SW, Mayo Clinic, Rochester, MN 55905.

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http://dx.doi.org/10.1007/s11306-016-1066-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976774PMC
July 2016

Module-based association analysis for omics data with network structure.

PLoS One 2015 30;10(3):e0122309. Epub 2015 Mar 30.

Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, 27695, United States of America; Department of Statistics, North Carolina State University, Raleigh, North Carolina, 27695, United States of America; Department of Statistics, National Cheng-Kung University, Taiwan, R.O.C.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122309PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378989PMC
March 2016

Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study.

J Am Heart Assoc 2015 Oct 26;4(10):e002203. Epub 2015 Oct 26.

Duke University Medical Center, Durham, NC (A.G., R.K.D.) Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC (R.K.D.) Duke Institute for Brain Sciences, Duke University, Durham, NC (R.K.D.) Institute of Genome Science and Policy, Durham, NC (R.K.D.).

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http://dx.doi.org/10.1161/JAHA.115.002203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845113PMC
October 2015

Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans.

Alzheimers Dement 2015 Jul;11(7):792-814

Department of Radiology, University of California-San Francisco, San Francisco, CA, USA; Department of Medicine, University of California-San Francisco, San Francisco, CA, USA; Department of Psychiatry, University of California-San Francisco, San Francisco, CA, USA; Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2015.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510473PMC
July 2015

Associations between purine metabolites and monoamine neurotransmitters in first-episode psychosis.

Front Cell Neurosci 2013 11;7:90. Epub 2013 Jun 11.

Medical Research Service, VA Pittsburgh Healthcare System Pittsburgh, PA, USA ; Department of Psychiatry, University of Pittsburgh School of Medicine Pittsburgh, PA, USA ; Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy Pittsburgh, PA, USA.

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http://dx.doi.org/10.3389/fncel.2013.00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678099PMC
June 2013

Impaired plasmalogens in patients with schizophrenia.

Psychiatry Res 2012 Aug 16;198(3):347-52. Epub 2012 Apr 16.

Duke University Medical Center, Department of Psychiatry and Behavioral Sciences, DUMC Box 3950 Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.psychres.2012.02.019DOI Listing
August 2012

Metabolomic changes in autopsy-confirmed Alzheimer's disease.

Alzheimers Dement 2011 May 13;7(3):309-17. Epub 2010 Nov 13.

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1016/j.jalz.2010.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061205PMC
May 2011

Metabolomic differences in heart failure patients with and without major depression.

J Geriatr Psychiatry Neurol 2010 Jun 25;23(2):138-46. Epub 2010 Jan 25.

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1177/0891988709358592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279728PMC
June 2010

Opioid use affects antioxidant activity and purine metabolism: preliminary results.

Hum Psychopharmacol 2009 Dec;24(8):666-75

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, 2218 Elder Street, Durham, NC 27705, USA.

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http://doi.wiley.com/10.1002/hup.1068
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http://dx.doi.org/10.1002/hup.1068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183957PMC
December 2009

Alterations in tryptophan and purine metabolism in cocaine addiction: a metabolomic study.

Psychopharmacology (Berl) 2009 Oct 1;206(3):479-89. Epub 2009 Aug 1.

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1007/s00213-009-1625-1DOI Listing
October 2009

Metabolomics tools for identifying biomarkers for neuropsychiatric diseases.

Neurobiol Dis 2009 Aug 19;35(2):165-76. Epub 2009 Mar 19.

Center for Bipolar Illness Intervention in Hispanic Communities, Department of Psychiatry and University of Texas Health Science at San Antonio, San Antonio, TX, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09699961090005
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http://dx.doi.org/10.1016/j.nbd.2009.02.019DOI Listing
August 2009

Metabolomics: a global biochemical approach to the study of central nervous system diseases.

Neuropsychopharmacology 2009 Jan 8;34(1):173-86. Epub 2008 Oct 8.

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1038/npp.2008.174DOI Listing
January 2009

Metabolomics: a global biochemical approach to drug response and disease.

Annu Rev Pharmacol Toxicol 2008 ;48:653-83

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.

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http://www.annualreviews.org/doi/10.1146/annurev.pharmtox.48
Publisher Site
http://dx.doi.org/10.1146/annurev.pharmtox.48.113006.094715DOI Listing
March 2008

Metabolomics in the study of aging and caloric restriction.

Methods Mol Biol 2007 ;371:393-409

Dementia Research Service, Burke Medical Research Institute, White Plains and Department of Neuroscience, Weill Medical College of Cornell University, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-59745-361-5_25DOI Listing
September 2007

A preliminary metabolomic analysis of older adults with and without depression.

Int J Geriatr Psychiatry 2007 May;22(5):418-23

Metabolon, Inc, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1002/gps.1690DOI Listing
May 2007

High-performance liquid chromatography separations coupled with coulometric electrode array detectors: a unique approach to metabolomics.

Methods Mol Biol 2007 ;358:159-74

Dementia Research Service, Burke Medical Research Institute, White Plains, NY, USA.

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http://dx.doi.org/10.1007/978-1-59745-244-1_10DOI Listing
January 2007

Metabolic profiling of patients with schizophrenia.

PLoS Med 2006 Aug;3(8):e363

Department of Psychiatry, Duke University Medical Center, Durham, North Carolina, USA.

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https://dx.plos.org/10.1371/journal.pmed.0030363
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http://dx.doi.org/10.1371/journal.pmed.0030363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1551921PMC
August 2006

Metabolomics Standards Workshop and the development of international standards for reporting metabolomics experimental results.

Brief Bioinform 2006 Jun 24;7(2):159-65. Epub 2006 Apr 24.

Metabolomics and Informatics, National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health (NIH). 6707 Democracy Blvd, Room 791, MSC 5460, Bethesda, Maryland 20892-5460, USA.

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https://academic.oup.com/bib/article-lookup/doi/10.1093/bib/
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http://dx.doi.org/10.1093/bib/bbl008DOI Listing
June 2006

Biomarkers for amyotrophic lateral sclerosis.

Expert Rev Mol Diagn 2006 May;6(3):387-98

University of Pittsburgh, Department of Pathology, School of Medicine, ST S-420, 200 Lothrop Street, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1586/14737159.6.3.387DOI Listing
May 2006