Publications by authors named "Rikard Holmdahl"

100Publications

Natural polymorphism of Ym1 regulates pneumonitis through alternative activation of macrophages.

Sci Adv 2020 Oct 21;6(43). Epub 2020 Oct 21.

The National Local Joint Engineering Research Center of Biodiagnostics and Biotherapy, the Second Affiliated Hospital of Xi'an Jiaotong University, 710004 Xi'an, China.

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http://dx.doi.org/10.1126/sciadv.aba9337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577715PMC
October 2020

Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2 complex.

J Leukoc Biol 2020 Oct 11. Epub 2020 Oct 11.

Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden, Sweden.

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http://dx.doi.org/10.1002/JLB.2HI0520-317RDOI Listing
October 2020

Vitamin D3 receptor polymorphisms regulate T cells and T cell-dependent inflammatory diseases.

Proc Natl Acad Sci U S A 2020 10 21;117(40):24986-24997. Epub 2020 Sep 21.

Division of Medical Inflammation Research, Department Of Medical Biochemistry and Biophysics, Karolinska Institute, 17176 Stockholm, Sweden;

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http://dx.doi.org/10.1073/pnas.2001966117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547217PMC
October 2020

[Strong inflammation is essential for expression of articular cartilage-specific citrullinated antigens].

Nan Fang Yi Ke Da Xue Xue Bao 2020 Aug;40(8):1081-1089

SMU-KI United Medical Inflammation Center, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.

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http://dx.doi.org/10.12122/j.issn.1673-4254.2020.08.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429155PMC
August 2020

Identification of Clec4b as a novel regulator of bystander activation of auto-reactive T cells and autoimmune disease.

PLoS Genet 2020 06 4;16(6):e1008788. Epub 2020 Jun 4.

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1371/journal.pgen.1008788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297379PMC
June 2020

Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis.

Arthritis Res Ther 2020 05 24;22(1):120. Epub 2020 May 24.

SMU-KI United Medical Inflammation Center, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.

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http://dx.doi.org/10.1186/s13075-020-02169-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245816PMC
May 2020

Self-reactive T cells induce and perpetuate chronic relapsing arthritis.

Arthritis Res Ther 2020 04 28;22(1):95. Epub 2020 Apr 28.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13075-020-2104-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187533PMC
April 2020

Independent and inter-dependent immunoregulatory effects of NCF1 and NOS2 in experimental autoimmune encephalomyelitis.

J Neuroinflammation 2020 Apr 11;17(1):113. Epub 2020 Apr 11.

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, 17177, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12974-020-01789-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149911PMC
April 2020

Regulation of T Cell Function by Reactive Nitrogen and Oxygen Species in Collagen-Induced Arthritis.

Antioxid Redox Signal 2020 01;32(3):161-172

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1089/ars.2019.7788DOI Listing
January 2020

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages William W Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Francesco Annunziato Achille Anselmo Petra Bacher Cosima T Baldari Sudipto Bari Vincenzo Barnaba Joana Barros-Martins Luca Battistini Wolfgang Bauer Sabine Baumgart Nicole Baumgarth Dirk Baumjohann Bianka Baying Mary Bebawy Burkhard Becher Wolfgang Beisker Vladimir Benes Rudi Beyaert Alfonso Blanco Dominic A Boardman Christian Bogdan Jessica G Borger Giovanna Borsellino Philip E Boulais Jolene A Bradford Dirk Brenner Ryan R Brinkman Anna E S Brooks Dirk H Busch Martin Büscher Timothy P Bushnell Federica Calzetti Garth Cameron Ilenia Cammarata Xuetao Cao Susanna L Cardell Stefano Casola Marco A Cassatella Andrea Cavani Antonio Celada Lucienne Chatenoud Pratip K Chattopadhyay Sue Chow Eleni Christakou Luka Čičin-Šain Mario Clerici Federico S Colombo Laura Cook Anne Cooke Andrea M Cooper Alexandra J Corbett Antonio Cosma Lorenzo Cosmi Pierre G Coulie Ana Cumano Ljiljana Cvetkovic Van Duc Dang Chantip Dang-Heine Martin S Davey Derek Davies Sara De Biasi Genny Del Zotto Gelo Victoriano Dela Cruz Michael Delacher Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing James P Di Santo Andreas Diefenbach Francesco Dieli Andreas Dolf Thomas Dörner Regine J Dress Diana Dudziak Michael Dustin Charles-Antoine Dutertre Friederike Ebner Sidonia B G Eckle Matthias Edinger Pascale Eede Götz R A Ehrhardt Marcus Eich Pablo Engel Britta Engelhardt Anna Erdei Charlotte Esser Bart Everts Maximilien Evrard Christine S Falk Todd A Fehniger Mar Felipo-Benavent Helen Ferry Markus Feuerer Andrew Filby Kata Filkor Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Britta Frehse Paul S Frenette Stefan Frischbutter Wolfgang Fritzsche David W Galbraith Anastasia Gangaev Natalio Garbi Brice Gaudilliere Ricardo T Gazzinelli Jens Geginat Wilhelm Gerner Nicholas A Gherardin Kamran Ghoreschi Lara Gibellini Florent Ginhoux Keisuke Goda Dale I Godfrey Christoph Goettlinger Jose M González-Navajas Carl S Goodyear Andrea Gori Jane L Grogan Daryl Grummitt Andreas Grützkau Claudia Haftmann Jonas Hahn Hamida Hammad Günter Hämmerling Leo Hansmann Goran Hansson Christopher M Harpur Susanne Hartmann Andrea Hauser Anja E Hauser David L Haviland David Hedley Daniela C Hernández Guadalupe Herrera Martin Herrmann Christoph Hess Thomas Höfer Petra Hoffmann Kristin Hogquist Tristan Holland Thomas Höllt Rikard Holmdahl Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Fang-Ping Huang Johanna E Huber Jochen Huehn Michael Hundemer Christopher A Hunter William Y K Hwang Anna Iannone Florian Ingelfinger Sabine M Ivison Hans-Martin Jäck Peter K Jani Beatriz Jávega Stipan Jonjic Toralf Kaiser Tomas Kalina Thomas Kamradt Stefan H E Kaufmann Baerbel Keller Steven L C Ketelaars Ahad Khalilnezhad Srijit Khan Jan Kisielow Paul Klenerman Jasmin Knopf Hui-Fern Koay Katja Kobow Jay K Kolls Wan Ting Kong Manfred Kopf Thomas Korn Katharina Kriegsmann Hendy Kristyanto Thomas Kroneis Andreas Krueger Jenny Kühne Christian Kukat Désirée Kunkel Heike Kunze-Schumacher Tomohiro Kurosaki Christian Kurts Pia Kvistborg Immanuel Kwok Jonathan Landry Olivier Lantz Paola Lanuti Francesca LaRosa Agnès Lehuen Salomé LeibundGut-Landmann Michael D Leipold Leslie Y T Leung Megan K Levings Andreia C Lino Francesco Liotta Virginia Litwin Yanling Liu Hans-Gustaf Ljunggren Michael Lohoff Giovanna Lombardi Lilly Lopez Miguel López-Botet Amy E Lovett-Racke Erik Lubberts Herve Luche Burkhard Ludewig Enrico Lugli Sebastian Lunemann Holden T Maecker Laura Maggi Orla Maguire Florian Mair Kerstin H Mair Alberto Mantovani Rudolf A Manz Aaron J Marshall Alicia Martínez-Romero Glòria Martrus Ivana Marventano Wlodzimierz Maslinski Giuseppe Matarese Anna Vittoria Mattioli Christian Maueröder Alessio Mazzoni James McCluskey Mairi McGrath Helen M McGuire Iain B McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Stephen D Miller Kingston H G Mills Hans Minderman Jenny Mjösberg Jonni Moore Barry Moran Lorenzo Moretta Tim R Mosmann Susann Müller Gabriele Multhoff Luis Enrique Muñoz Christian Münz Toshinori Nakayama Milena Nasi Katrin Neumann Lai Guan Ng Antonia Niedobitek Sussan Nourshargh Gabriel Núñez José-Enrique O'Connor Aaron Ochel Anna Oja Diana Ordonez Alberto Orfao Eva Orlowski-Oliver Wenjun Ouyang Annette Oxenius Raghavendra Palankar Isabel Panse Kovit Pattanapanyasat Malte Paulsen Dinko Pavlinic Livius Penter Pärt Peterson Christian Peth Jordi Petriz Federica Piancone Winfried F Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Zhiyong Poon Katharina Pracht Immo Prinz Carlo E M Pucillo Sally A Quataert Linda Quatrini Kylie M Quinn Helena Radbruch Tim R D J Radstake Susann Rahmig Hans-Peter Rahn Bartek Rajwa Gevitha Ravichandran Yotam Raz Jonathan A Rebhahn Diether Recktenwald Dorothea Reimer Caetano 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Eur J Immunol 2019 Oct;49(10):1457-1973

Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.201970107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350392PMC
October 2019

Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise.

Nat Commun 2019 10 11;10(1):4623. Epub 2019 Oct 11.

Department of Nutrition, Exercise and Sports, Section of Molecular Physiology, University of Copenhagen, Universitetsparken 13, 2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41467-019-12523-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789013PMC
October 2019

NOX2 mediates quiescent handling of dead cell remnants in phagocytes.

Redox Biol 2019 09 20;26:101279. Epub 2019 Jul 20.

Department of Medicine 3, Rheumatology and Immunology, Friedrich Alexander-University Erlangen-Nürnberg, Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669319PMC
September 2019

Low Production of Reactive Oxygen Species Drives Systemic Lupus Erythematosus.

Trends Mol Med 2019 10 11;25(10):826-835. Epub 2019 Jul 11.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2019.06.001DOI Listing
October 2019

The structure, specificity and function of anti-citrullinated protein antibodies.

Nat Rev Rheumatol 2019 08 28;15(8):503-508. Epub 2019 Jun 28.

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41584-019-0244-4DOI Listing
August 2019

Comment on editorial 'Pathogenic effector functions of ACPA: where do we stand?'

Authors:
Rikard Holmdahl

Ann Rheum Dis 2020 10 21;79(10):e126. Epub 2019 Jun 21.

Departmet of Medical Biochemistry and Biophysics, Section of Medical Inflammation Research, Karolinska Institute, Stockholm, Sweden

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http://dx.doi.org/10.1136/annrheumdis-2019-215857DOI Listing
October 2020

Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949.

Biochem Pharmacol 2019 08 11;166:163-173. Epub 2019 May 11.

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm 17177, Sweden.

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http://dx.doi.org/10.1016/j.bcp.2019.04.030DOI Listing
August 2019

Editorial: Autoantibodies.

Front Immunol 2019 2;10:484. Epub 2019 Apr 2.

Lübeck Institute of Experimental Dermatology and Center for Research on Inflammation of the Skin, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.00484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454132PMC
July 2020

Editorial: Oxidants and Redox Signaling in Inflammation.

Front Immunol 2019 26;10:545. Epub 2019 Mar 26.

Vascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA, United States.

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http://dx.doi.org/10.3389/fimmu.2019.00545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448005PMC
June 2020

The autoantibody response to cyclic citrullinated collagen type II peptides in rheumatoid arthritis.

Rheumatology (Oxford) 2019 09;58(9):1623-1633

Department of Medical Biochemistry and Biophysics, Section for Medical Inflammation Research, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1093/rheumatology/kez073DOI Listing
September 2019

The Specificity of Monoclonal Anti-Citrullinated Protein Antibodies: Comment on the Article by Steen et al.

Authors:
Rikard Holmdahl

Arthritis Rheumatol 2019 02 9;71(2):324-325. Epub 2019 Jan 9.

Karolinska Institutet, Stockholm, Sweden.

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http://doi.wiley.com/10.1002/art.40758
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http://dx.doi.org/10.1002/art.40758DOI Listing
February 2019

Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.

Arthritis Rheumatol 2019 02 4;71(2):210-221. Epub 2019 Jan 4.

Karolinska Institutet, Stockholm, Sweden, and Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.1002/art.40698DOI Listing
February 2019

Regulatory T cells control epitope spreading in autoimmune arthritis independent of cytotoxic T-lymphocyte antigen-4.

Immunology 2018 12 31;155(4):446-457. Epub 2018 Jul 31.

Section for Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.

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http://doi.wiley.com/10.1111/imm.12983
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http://dx.doi.org/10.1111/imm.12983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231009PMC
December 2018

Mannan-induced Nos2 in macrophages enhances IL-17-driven psoriatic arthritis by innate lymphocytes.

Sci Adv 2018 05 16;4(5):eaas9864. Epub 2018 May 16.

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 171 77, Sweden.

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http://dx.doi.org/10.1126/sciadv.aas9864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955621PMC
May 2018

Dynamics Determine Signaling in a Multicomponent System Associated with Rheumatoid Arthritis.

J Med Chem 2018 06 24;61(11):4774-4790. Epub 2018 May 24.

Department of Chemistry , Umeå University , SE-901 87 Umeå , Sweden.

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http://pubs.acs.org/doi/10.1021/acs.jmedchem.7b01880
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http://dx.doi.org/10.1021/acs.jmedchem.7b01880DOI Listing
June 2018

Association of NOX2 subunits genetic variants with autoimmune diseases.

Free Radic Biol Med 2018 09 9;125:72-80. Epub 2018 Mar 9.

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2018.03.005DOI Listing
September 2018

Increased salt exposure affects both lymphoid and myeloid effector functions, influencing innate-associated disease but not T-cell-associated autoimmunity.

Immunology 2018 Mar 7. Epub 2018 Mar 7.

Section for Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/imm.12923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050215PMC
March 2018

T cells specific for post-translational modifications escape intrathymic tolerance induction.

Nat Commun 2018 01 24;9(1):353. Epub 2018 Jan 24.

Section for Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Scheeles väg 2, 17177, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41467-017-02763-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783942PMC
January 2018

Cutting Edge: Processing of Oxidized Peptides in Macrophages Regulates T Cell Activation and Development of Autoimmune Arthritis.

J Immunol 2017 12 10;199(12):3937-3942. Epub 2017 Nov 10.

Section for Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, 171 77 Stockholm, Sweden;

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http://dx.doi.org/10.4049/jimmunol.1700774DOI Listing
December 2017

Influence of hydrocarbon oil structure on adjuvanticity and autoimmunity.

Sci Rep 2017 11 8;7(1):14998. Epub 2017 Nov 8.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41598-017-15096-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678145PMC
November 2017

Germinal Center B Cells Are Essential for Collagen-Induced Arthritis.

Arthritis Rheumatol 2018 02 22;70(2):193-203. Epub 2018 Jan 22.

Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/art.40354DOI Listing
February 2018

A single nucleotide polymorphism in the gene leading to reduced oxidative burst is associated with systemic lupus erythematosus.

Ann Rheum Dis 2017 Sep 12;76(9):1607-1613. Epub 2017 Jun 12.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1136/annrheumdis-2017-211287DOI Listing
September 2017

CTLA-4 expressed by FOXP3 regulatory T cells prevents inflammatory tissue attack and not T-cell priming in arthritis.

Immunology 2017 09 20;152(1):125-137. Epub 2017 Jun 20.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/imm.12754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543501PMC
September 2017

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

Antioxid Redox Signal 2017 Dec 1;27(18):1473-1490. Epub 2017 Jun 1.

1 Medicity Research Laboratory, University of Turku , Turku, Finland .

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http://dx.doi.org/10.1089/ars.2016.6981DOI Listing
December 2017

The Major Histocompatibility Complex Class III Haplotype Ltab-Ncr3 Regulates Adjuvant-Induced but Not Antigen-Induced Autoimmunity.

Am J Pathol 2017 May 18;187(5):987-998. Epub 2017 Mar 18.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.12.022DOI Listing
May 2017

MHC class II alleles associated with Th1 rather than Th17 type immunity drive the onset of early arthritis in a rat model of rheumatoid arthritis.

Eur J Immunol 2017 03 14;47(3):563-574. Epub 2017 Feb 14.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/eji.201646760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163699PMC
March 2017

Pristane induces autophagy in macrophages, promoting a STAT1-IRF1-TLR3 pathway and arthritis.

Clin Immunol 2017 02 7;175:56-68. Epub 2016 Dec 7.

Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710061, China; Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University), Ministry of Education, Xi'an, Shaanxi 710061, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.11.017DOI Listing
February 2017

Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases.

Immunology 2017 04 22;150(4):408-417. Epub 2016 Dec 22.

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/imm.12692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343355PMC
April 2017

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

BMC Musculoskelet Disord 2016 11 9;17(1):464. Epub 2016 Nov 9.

Department of Rheumatology and Inflammation Research, Centre for Bone and Arthritis Research (CBAR), Sahlgrenska Academy, University of Gothenburg, Box 480, 405 30, Göteborg, Sweden.

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http://bmcmusculoskeletdisord.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/s12891-016-1315-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103594PMC
November 2016

Reply to Liu et al.: Translation of rat congenic data to humans on a conserved MHC-III haplotype associated with rheumatoid arthritis.

Proc Natl Acad Sci U S A 2016 10 11;113(42):E6323-E6324. Epub 2016 Oct 11.

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden; Center for Medical Immunpharmacology Research, Southern Medical University, Guangzhou 510515, China

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http://dx.doi.org/10.1073/pnas.1614662113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081618PMC
October 2016

Enhanced XOR activity in eNOS-deficient mice: Effects on the nitrate-nitrite-NO pathway and ROS homeostasis.

Free Radic Biol Med 2016 10 5;99:472-484. Epub 2016 Sep 5.

Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.09.004DOI Listing
October 2016

Rheumatoid arthritis: identifying and characterising polymorphisms using rat models.

Dis Model Mech 2016 10;9(10):1111-1123

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden Southern Medical University, Guangzhou 510515, China

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http://dx.doi.org/10.1242/dmm.026435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087835PMC
October 2016

(18)F-Labeling of Mannan for Inflammation Research with Positron Emission Tomography.

ACS Med Chem Lett 2016 Sep 16;7(9):826-30. Epub 2016 May 16.

Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, FI-20520 Turku, Finland; Turku PET Centre, Turku University Hospital, Kiinamyllynkatu 4-8, FI-20520 Turku, Finland; Turku Center for Disease Modeling, University of Turku, FI-20014 Turku, Finland.

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http://dx.doi.org/10.1021/acsmedchemlett.6b00160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018871PMC
September 2016

Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples.

Mol Cell Proteomics 2016 09 24;15(9):3017-29. Epub 2016 Jul 24.

§Division of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden; ‖Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.1074/mcp.M116.060764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013314PMC
September 2016

Reactive Oxygen Species Regulate Innate But Not Adaptive Inflammation in ZAP70-Mutated SKG Arthritic Mice.

Am J Pathol 2016 09 15;186(9):2353-63. Epub 2016 Jul 15.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.05.014DOI Listing
September 2016

Conserved 33-kb haplotype in the MHC class III region regulates chronic arthritis.

Proc Natl Acad Sci U S A 2016 06 14;113(26):E3716-24. Epub 2016 Jun 14.

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden; Southern Medical University, Guangzhou 510515, China

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http://dx.doi.org/10.1073/pnas.1600567113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932949PMC
June 2016

Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis.

Arthritis Res Ther 2016 06 14;18(1):140. Epub 2016 Jun 14.

Department of Rheumatology and Inflammation Research, Institute for Medicine, Sahlgrenska Academy, University of Gothenburg, Box 480, SE 405 30, Gothenburg, Sweden.

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http://dx.doi.org/10.1186/s13075-016-1037-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908726PMC
June 2016

A Reduction in Intracellular Reactive Oxygen Species Due to a Mutation in NCF4 Promotes Autoimmune Arthritis in Mice.

Antioxid Redox Signal 2016 12 8;25(18):983-996. Epub 2016 Jul 8.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute , Stockholm, Sweden .

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http://dx.doi.org/10.1089/ars.2016.6675DOI Listing
December 2016

How well do ACPA discriminate and predict RA in the general population: a study based on 12 590 population-representative Swedish twins.

Ann Rheum Dis 2017 Jan 28;76(1):119-125. Epub 2016 Apr 28.

Unit of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1136/annrheumdis-2015-208980DOI Listing
January 2017

Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood.

Proc Natl Acad Sci U S A 2016 Apr 11;113(17):E2383-92. Epub 2016 Apr 11.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-17177 Stockholm, Sweden;

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http://dx.doi.org/10.1073/pnas.1603892113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855592PMC
April 2016

Reply.

Arthritis Rheumatol 2016 08;68(8):2053-4

Karolinska University Hospital Solna and Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1002/art.39660DOI Listing
August 2016

Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation.

Immunol Rev 2016 Jan;269(1):228-47

Section for Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/imr.12378DOI Listing
January 2016

A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism.

Hepatology 2016 07 22;64(1):58-72. Epub 2016 Jan 22.

Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.

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http://dx.doi.org/10.1002/hep.28391DOI Listing
July 2016

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

PLoS One 2015 3;10(11):e0141974. Epub 2015 Nov 3.

Medicity Research Laboratory, University of Turku, Turku, Finland; Medical Inflammation Research, Karolinska Institutet, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0141974PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631371PMC
June 2016

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant.

Immunology 2016 Jan 24;147(1):125-32. Epub 2015 Nov 24.

Medical Inflammation Research, Department of Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1111/imm.12546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693874PMC
January 2016

System A amino acid transporters regulate glutamine uptake and attenuate antibody-mediated arthritis.

Immunology 2015 Dec 5;146(4):607-17. Epub 2015 Oct 5.

Section for Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/imm.12531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693895PMC
December 2015

Methylcholanthrene-Induced Sarcomas Develop Independently from NOX2-Derived ROS.

PLoS One 2015 15;10(6):e0129786. Epub 2015 Jun 15.

Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129786PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468117PMC
March 2016

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

Eur J Immunol 2015 Aug 3;45(8):2243-51. Epub 2015 Jun 3.

Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/eji.201545518DOI Listing
August 2015

Reactive oxygen species in psoriasis and psoriasis arthritis: relevance to human disease.

Int Arch Allergy Immunol 2015 20;166(2):135-49. Epub 2015 Mar 20.

Division of Medical Inflammation Research, Department of Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1159/000375401DOI Listing
July 2015

Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.

Eur J Immunol 2015 May 19;45(5):1348-53. Epub 2015 Mar 19.

Medical Inflammation Research, Department of Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1002/eji.201445020DOI Listing
May 2015

Positional identification of RT1-B (HLA-DQ) as susceptibility locus for autoimmune arthritis.

J Immunol 2015 Mar 11;194(6):2539-50. Epub 2015 Feb 11.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77, Stockholm, Sweden;

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http://dx.doi.org/10.4049/jimmunol.1402238DOI Listing
March 2015

Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats.

Mol Cell Endocrinol 2015 Feb 19;402:1-12. Epub 2014 Dec 19.

Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710061, China; Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University), Ministry of Education of China, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2014.12.007DOI Listing
February 2015

Pristane primed rat T cells enhance TLR3 expression of fibroblast-like synoviocytes via TNF-α initiated p38 MAPK and NF-κB pathways.

Clin Immunol 2015 Feb 19;156(2):141-53. Epub 2014 Dec 19.

Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710061, China; Key Laboratory of Environment and Genes Related to Diseases, Xi'an Jiaotong University, Ministry of Education, Xi'an, Shaanxi 710061, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2014.11.008DOI Listing
February 2015

Tryptophan catabolism is unaffected in chronic granulomatous disease.

Nature 2014 Oct;514(7523):E16-7

1] Vascular Biology Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales 2010, Australia [2] School of Medicine, University of New South Wales, New South Wales 2052, Australia [3] School of Medical Sciences and Bosch Institute, The University of Sydney, Camperdown, New South Wales 2050, Australia.

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http://dx.doi.org/10.1038/nature13844DOI Listing
October 2014

Clever-1/stabilin-1 controls cancer growth and metastasis.

Clin Cancer Res 2014 Dec 15;20(24):6452-64. Epub 2014 Oct 15.

MediCity Research Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland. National Institute for Health and Welfare, Turku, Finland. Department of Medical Microbiology and Immunology, University of Turku, Turku, Finland.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1236DOI Listing
December 2014