Publications by authors named "Ricky A Sharma"

78Publications

The multidisciplinary management of oligometastases from colorectal cancer: a narrative review.

Ann Palliat Med 2020 Sep 7. Epub 2020 Sep 7.

UCL Cancer Institute, University College London, London, UK.

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September 2020

Radiosensitisation of Hepatocellular Carcinoma Cells by Vandetanib.

Cancers (Basel) 2020 Jul 13;12(7). Epub 2020 Jul 13.

University College London Cancer Institute, University College London, London WC1E 6BT, UK.

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July 2020

Development and Implementation of an End-To-End Test for Absolute Dose Verification of Small Animal Preclinical Irradiation Research Platforms.

Int J Radiat Oncol Biol Phys 2020 Jul 10;107(3):587-596. Epub 2020 Mar 10.

Medical Physics Department, National Physical Laboratory, Teddington, United Kingdom; Department of Physics, Faculty of Engineering and Physical Sciences. University of Surrey, Guildford, United Kingdom.

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July 2020

Quality of life in the FOXFIRE, SIRFLOX and FOXFIRE-global randomised trials of selective internal radiotherapy for metastatic colorectal cancer.

Int J Cancer 2020 Aug 9;147(4):1078-1085. Epub 2020 Jan 9.

University College London Hospitals Biomedical Research Centre, NIHR, UCL Cancer Institute, University College London, London, United Kingdom.

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August 2020

Yttrium-90 Transarterial Radioembolization for Chemotherapy-Refractory Intrahepatic Cholangiocarcinoma: A Prospective, Observational Study.

J Vasc Interv Radiol 2019 Aug 27;30(8):1185-1192. Epub 2019 Jun 27.

University College London (UCL) Cancer Institute, National Institute for Health Research UCL Hospitals Biomedical Research Centre, University College London, 72 Huntley Street, London WC1E 6DD, United Kingdom. Electronic address:

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August 2019

How rapid advances in imaging are defining the future of precision radiation oncology.

Br J Cancer 2019 04 26;120(8):779-790. Epub 2019 Mar 26.

Cancer Institute, University College London, London, UK.

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April 2019

Clinical Development of Novel Drug-Radiotherapy Combinations.

Clin Cancer Res 2019 03 29;25(5):1455-1461. Epub 2018 Nov 29.

Radiation Oncology, NIHR University College London Hospitals Biomedical Research Centre, University College London Cancer Institute, University College London, London, United Kingdom.

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March 2019

Long-term radiological and histological outcomes following selective internal radiation therapy to liver metastases from breast cancer.

Radiol Case Rep 2018 Dec 22;13(6):1259-1266. Epub 2018 Sep 22.

Department of Oncology, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 7LE, United Kingdom.

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December 2018

Beyond the Knife: The Evolving Nonsurgical Management of Oligometastatic Colorectal Cancer.

Am Soc Clin Oncol Educ Book 2018 May;38:209-219

From the BC Cancer-Vancouver and Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada; National Institute for Health Research University College London Hospitals Biomedical Research Centre, UCL Cancer Institute, University College, London, United Kingdom.

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May 2018

Assessment of medical devices: the Emperor's new clothes: Author reply.

Br J Radiol 2018 06 11;91(1086):20180310. Epub 2018 May 11.

7 European Medicines Agency , London , UK.

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June 2018

4D-PET reconstruction using a spline-residue model with spatial and temporal roughness penalties.

Phys Med Biol 2018 05 4;63(9):095013. Epub 2018 May 4.

Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom. Author to whom any correspondence should be addressed.

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May 2018

Locoregional therapies in cholangiocarcinoma.

Hepat Oncol 2017 Oct 17;4(4):99-109. Epub 2017 Nov 17.

UCL Institute for Liver & Digestive Health, Royal Free Hospital Campus, Royal Free Hospital, Pond Street, London, NW3 2QG, UK.

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October 2017

Adequate SIRT activity dose is as important as adequate chemotherapy dose - Authors' reply.

Lancet Oncol 2017 11 31;18(11):e637. Epub 2017 Oct 31.

Imperial College Healthcare NHS Trust & Imperial College, Hammersmith Hospital, London, UK.

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November 2017

First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials.

Lancet Oncol 2017 09 3;18(9):1159-1171. Epub 2017 Aug 3.

Cancer Research UK Medical Research Council (CRUK-MRC) Oxford Institute for Radiation Oncology, University of Oxford, Oxford, UK; National Institute for Health Research University College London Hospitals Biomedical Research Centre, UCL Cancer Institute, London, UK. Electronic address:

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September 2017

The need for multidisciplinarity in specialist training to optimize future patient care.

Nat Rev Clin Oncol 2017 Aug 29;14(8):508-517. Epub 2016 Nov 29.

NIHR University College London Hospitals Biomedical Research Centre, UCL Cancer Institute, University College London, London WC1E 6DD, UK.

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August 2017

Imaging oligometastatic cancer before local treatment.

Lancet Oncol 2016 09 30;17(9):e406-14. Epub 2016 Aug 30.

Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK; Department of Oncology, University of Oxford, UK.

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September 2016

Landmark study raises the bar for interventional oncology.

Future Oncol 2016 Aug 23;12(15):1747-9. Epub 2016 Jun 23.

Oncology Department, Old Research Campus Research Building, University of Oxford, Oxford, OX3 7DQ, UK.

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August 2016

Pieces-of-parts for supervoxel segmentation with global context: Application to DCE-MRI tumour delineation.

Med Image Anal 2016 08 21;32:69-83. Epub 2016 Mar 21.

Institute of Biomedical Engineering, Department of Engineering Science, Old Road Campus Research Building, University of Oxford, Headington, Oxford OX3 7DQ, UK; Department of Biomedical Engineering, Division of Imaging Sciences and Biomedical Engineering, King's College London, St Thomas' Hospital, London SE1 7EH, UK.

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August 2016

Management of a thyroid "incidentaloma" in a patient with cancer: a case report.

Int Med Case Rep J 2015 16;8:247-9. Epub 2015 Oct 16.

CRUK-MRC Oxford Institute for Radiation Oncology, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Trust, University of Oxford, Oxford, UK.

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October 2015

Surgery versus SABR for resectable non-small-cell lung cancer.

Lancet Oncol 2015 Aug;16(8):e373-4

National Institute for Health Research Oxford Biomedical Research Centre, Cancer Research UK, University of Oxford, OX3 7DQ, Oxford, UK; Medical Research Council Oxford Institute for Radiation Oncology, University of Oxford, OX3 7DQ, Oxford, UK. Electronic address:

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August 2015

Clinical trials of interventional oncology-moving from efficacy to outcomes.

Nat Rev Clin Oncol 2015 Feb 9;12(2):93-104. Epub 2014 Dec 9.

CRUK-MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK.

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February 2015

Case histories in unresectable liver-dominant metastatic colorectal cancer.

Future Oncol 2014 Nov;10(15 Suppl):41-7

CRUK-MRC Oxford Institute for Radiation Oncology, Department of Oncology, Old Road Campus Research Building, University of Oxford, Oxford, OX3 7DQ, UK.

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November 2014

Consumer involvement in cancer research: example from a Cancer Network.

Health Expect 2015 Oct 14;18(5):1530-42. Epub 2013 Oct 14.

Thames Valley Cancer Research Network, Oxford, UK.

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October 2015

XPF protein levels determine sensitivity of malignant melanoma cells to oxaliplatin chemotherapy: suitability as a biomarker for patient selection.

Int J Cancer 2014 Mar 14;134(6):1495-503. Epub 2013 Nov 14.

Department of Oncology, Oxford NIHR Biomedical Research Centre, Cancer Research UK-Medical Research Council Gray Institute for Radiation Oncology & Biology, University of Oxford, Oxford, Oxfordshire, OX3 7DQ, United Kingdom.

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March 2014

Anatomical basis and histopathological changes resulting from selective internal radiotherapy for liver metastases.

J Clin Pathol 2013 Mar 16;66(3):205-11. Epub 2012 Nov 16.

Department of Cellular Pathology, Oxford University Hospitals NHS Trust, John Radcliffe Hospital, Oxford, UK.

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March 2013

Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.

Carcinogenesis 2012 Nov 20;33(11):2026-34. Epub 2012 Jul 20.

Cancer Research UK-Medical Research Council Gray Institute for Radiation Oncology and Biology, Oncology Department, Old Road Campus Research Building, University of Oxford, Oxford OX3 7DQ, UK.

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November 2012

Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.

Antioxid Redox Signal 2013 Mar 5;18(8):851-73. Epub 2012 Sep 5.

Cancer Research UK-Medical Research Council, Oncology Department, Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, United Kingdom.

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March 2013

Pathological grading of regression following neoadjuvant chemoradiation therapy: the clinical need is now.

J Clin Pathol 2012 Oct 25;65(10):867-71. Epub 2012 Jun 25.

Oncology Department, Old Road Research Campus Building, Oxford, United Kingdom, OX3 7DQ.

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October 2012

Oxaliplatin as a radiosensitiser for upper and lower gastrointestinal tract malignancies: what have we learned from a decade of translational research?

Crit Rev Oncol Hematol 2012 Sep 5;83(3):353-87. Epub 2012 Feb 5.

Gray Institute of Radiation Oncology and Biology, Oncology Department, Old Road Campus Research Building, Oxford OX3 7DQ, UK.

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September 2012

Biological relevance of DNA polymerase β and translesion synthesis polymerases to cancer and its treatment.

Curr Mol Pharmacol 2012 Jan;5(1):54-67

Cancer Research UK-Medical Research Council Gray Institute, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK.

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January 2012

Intra-arterial brachytherapy of hepatic malignancies: watch the flow.

Nat Rev Clin Oncol 2011 Feb 5;8(2):115-20. Epub 2010 Oct 5.

Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester Royal Infirmary, Leicester LE1 5WW, UK.

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February 2011

Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells.

Cancer Res 2010 Jul 15;70(13):5389-98. Epub 2010 Jun 15.

Cancer Research UK-Medical Research Council, Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, United Kingdom.

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July 2010

Liver metastases from colorectal cancer: radioembolization with systemic therapy.

Nat Rev Clin Oncol 2009 Dec 3;6(12):687-97. Epub 2009 Nov 3.

Cancer Research UK-Medical Research Council Gray Institute for Radiation Oncology & Biology, University of Oxford, Old Road Campus Research Building, Oxford, UK.

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December 2009

Multidisciplinary team meetings: what does the future hold for the flies raised in Wittgenstein's bottle?

Lancet Oncol 2009 Feb;10(2):98-9

Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK.

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February 2009

Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials.

Antioxid Redox Signal 2008 Mar;10(3):511-45

Department of Medicine, Royal Marsden Hospital, London, England.

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March 2008

DNA repair pathways as targets for cancer therapy.

Nat Rev Cancer 2008 Mar;8(3):193-204

Radiation Oncology & Biology, University of Oxford, Old Road Campus Research Building, off Roosevelt Drive, Headington, Oxford, OX3 7DQ, UK.

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March 2008

Androgen manipulation alters oxidative DNA adduct levels in androgen-sensitive prostate cancer cells grown in vitro and in vivo.

Cancer Lett 2008 Mar 21;261(1):74-83. Epub 2007 Dec 21.

Cancer Biomarkers and Prevention Group, Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.

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March 2008

Targeting base excision repair to improve cancer therapies.

Mol Aspects Med 2007 Jun-Aug;28(3-4):345-74. Epub 2007 Jul 5.

Radiation Oncology & Biology, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.

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February 2008

Pharmacokinetics and pharmacodynamics of curcumin.

Adv Exp Med Biol 2007 ;595:453-70

Radiation Oncology & Biology, University of Oxford, Churchill Hospital, UK.

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July 2007

Neuron-specific enolase expression in multiple myeloma.

Lancet Oncol 2006 Nov;7(11):960

Department of Radiotherapy, Royal Marsden Hospital, London, UK.

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November 2006

Mechanisms of the self/non-self-survey in the defense against cancer: potential for chemoprevention?

Crit Rev Oncol Hematol 2005 Oct;56(1):5-22

Radiotherapy Department, Royal Marsden Hospital NHS Trust, Downs Road, Sutton SM2 5PT, UK.

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October 2005

Biological relevance of adduct detection to the chemoprevention of cancer.

Clin Cancer Res 2004 Aug;10(15):4901-12

Cancer Biomarkers and Prevention Group, Oncology Department, University of Leicester, Leicester Royal Infirmary, Leicester, United Kingdom.

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August 2004

Angiogenesis and the immune response as targets for the prevention and treatment of colorectal cancer (review).

Oncol Rep 2003 Sep-Oct;10(5):1625-31

University Department of Oncology, Leicester Royal Infirmary, Leicester LE1 5WW, UK.

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April 2004

Reversibility of liver failure secondary to metastatic breast cancer by vinorelbine and cisplatin chemotherapy.

Cancer Chemother Pharmacol 2003 Nov 18;52(5):367-70. Epub 2003 Jul 18.

Department of Oncology, Leicester Royal Infirmary, University Hospitals of Leicester, Leicester, LE1 5WW, UK.

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November 2003

Cancer prevention and delay are as important as cure.

Lancet Oncol 2003 Feb;4(2):72-3

Cancer Biomarkers and Prevention Group, Department of Oncology, University of Leicester, , Leicester, LE2 7LX, UK.

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February 2003

Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis.

Cancer Epidemiol Biomarkers Prev 2002 Jun;11(6):535-40

Cancer Biomarkers and Prevention Group, Department of Oncology, University of Leicester, Leicester, United Kingdom.

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June 2002