Rick M Maizels

Rick M Maizels

UNVERIFIED PROFILE

Are you Rick M Maizels?   Register this Author

Register author
Rick M Maizels

Rick M Maizels

Publications by authors named "Rick M Maizels"

Are you Rick M Maizels?   Register this Author

100Publications

1478Reads

50Profile Views

Organoids - New Models for Host-Helminth Interactions.

Trends Parasitol 2020 Feb 29;36(2):170-181. Epub 2019 Nov 29.

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pt.2019.10.013DOI Listing
February 2020

Macrophage Migration Inhibitory Factor (MIF) Is Essential for Type 2 Effector Cell Immunity to an Intestinal Helminth Parasite.

Front Immunol 2019 24;10:2375. Epub 2019 Oct 24.

Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.02375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821780PMC
October 2019

Regulation of Immunity and allergy by helminth parasites.

Authors:
Rick M Maizels

Allergy 2019 Jun 12. Epub 2019 Jun 12.

Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunology and Inflammation, University of Glasgow, Glasgow, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/all.13944DOI Listing
June 2019

Innate Lymphoid Cells in Helminth Infections-Obligatory or Accessory?

Front Immunol 2019 10;10:620. Epub 2019 Apr 10.

Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunology and Inflammation, University of Glasgow, Glasgow, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.00620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467944PMC
April 2019

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules.

Immunity 2018 11;49(5):801-818

Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2018.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269126PMC
November 2018

Secreted venom allergen-like proteins of helminths: Conserved modulators of host responses in animals and plants.

PLoS Pathog 2018 10 18;14(10):e1007300. Epub 2018 Oct 18.

Laboratory of Nematology, Plant Sciences Group, Wageningen University and Research, Wageningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1007300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193718PMC
October 2018

Helminth-induced IL-4 expands bystander memory CD8 T cells for early control of viral infection.

Nat Commun 2018 10 30;9(1):4516. Epub 2018 Oct 30.

Immunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine - FARAH, University of Liège, Avenue de Cureghem 10, 4000, Liège, Belgium.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41467-018-06978-5
Publisher Site
http://dx.doi.org/10.1038/s41467-018-06978-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207712PMC
October 2018

Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion.

Elife 2018 09 21;7. Epub 2018 Sep 21.

Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.

View Article

Download full-text PDF

Source
https://elifesciences.org/articles/38269
Publisher Site
http://dx.doi.org/10.7554/eLife.38269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173579PMC
September 2018

DEMONSTRATION OF THE ANTHELMINTIC POTENCY OF MARIMASTAT IN THE HELIGMOSOMOIDES POLYGYRUS RODENT MODEL.

J Parasitol 2018 Aug 29. Epub 2018 Aug 29.

** University of Edinburgh School of Biological Sciences Michael Swann Building, Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, EH9 3BF, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1645/18-33DOI Listing
August 2018

Crystal structure of Brugia malayi venom allergen-like protein-1 (BmVAL-1), a vaccine candidate for lymphatic filariasis.

Int J Parasitol 2018 04 6;48(5):371-378. Epub 2018 Mar 6.

National School of Tropical Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893361PMC
April 2018

Heligmosomoides polygyrus Venom Allergen-like Protein-4 (HpVAL-4) is a sterol binding protein.

Int J Parasitol 2018 04 2;48(5):359-369. Epub 2018 Mar 2.

Laboratory of Nematology, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2018.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893428PMC
April 2018

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus.

Int J Parasitol 2018 04 3;48(5):379-385. Epub 2018 Mar 3.

Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, UK; Institute of Infection and Immunology Research and Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904571PMC
April 2018

Special issue: molecular and cellular biology of helminth parasites XI.

Int J Parasitol 2018 04;48(5):319-320

Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunology and Inflammation, University of Glasgow, Glasgow G12 8TA, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2018.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261350PMC
April 2018

Human toxocariasis.

Lancet Infect Dis 2018 01 3;18(1):e14-e24. Epub 2017 Aug 3.

Department of Veterinary Biosciences, Melbourne Veterinary School, The University of Melbourne, Parkville, VIC, Australia. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S14733099173033
Publisher Site
http://dx.doi.org/10.1016/S1473-3099(17)30331-6DOI Listing
January 2018

Immunology: The Neuronal Pathway to Mucosal Immunity.

Curr Biol 2018 01;28(1):R33-R36

Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, College of Medical, Veterinary & Life Sciences, University of Glasgow, 120 University Place, Glasgow G12 8TA, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2017.11.025DOI Listing
January 2018

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota.

J Allergy Clin Immunol 2017 Oct 11;140(4):1068-1078.e6. Epub 2017 Feb 11.

MRC-Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom; Child Life and Health, University of Edinburgh, Edinburgh, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2017.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485385PMC
October 2017

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.

Immunity 2017 10;47(4):739-751.e5

MRC Centre for Inflammation Research, University of Edinburgh, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK; Institute of Immunology and Infection Research, and Centre for Immunity, Infection and Evolution, School of Biological Sciences, Ashworth Laboratories, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2017.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655542PMC
October 2017

Helminths in the gastrointestinal tract as modulators of immunity and pathology.

Am J Physiol Gastrointest Liver Physiol 2017 Jun 16;312(6):G537-G549. Epub 2017 Mar 16.

Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpgi.00024.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495915PMC
June 2017

Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity.

Cell Rep 2017 05;19(8):1545-1557

Institute of Immunology and Infection Research and Centre for Immunity, Infection & Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2017.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457486PMC
May 2017

Macrophage origin limits functional plasticity in helminth-bacterial co-infection.

PLoS Pathog 2017 03 23;13(3):e1006233. Epub 2017 Mar 23.

Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1006233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364000PMC
March 2017

Myeloid Cell Phenotypes in Susceptibility and Resistance to Helminth Parasite Infections.

Microbiol Spectr 2016 12;4(6)

Department of Biology, University of York, York YO10 5DD, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/microbiolspec.MCHD-0043-2016DOI Listing
December 2016

Regulation of the host immune system by helminth parasites.

J Allergy Clin Immunol 2016 09 29;138(3):666-675. Epub 2016 Jul 29.

Centre for Inflammation Research, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2016.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010150PMC
September 2016

Macrobiota - helminths as active participants and partners of the microbiota in host intestinal homeostasis.

Curr Opin Microbiol 2016 08 23;32:14-18. Epub 2016 Apr 23.

Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunology and Inflammation, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mib.2016.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983462PMC
August 2016

Host parasite communications-Messages from helminths for the immune system: Parasite communication and cell-cell interactions.

Mol Biochem Parasitol 2016 07 11;208(1):33-40. Epub 2016 Jun 11.

Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunology and Inflammation, University of Glasgow, 120 University Place, Glasgow, G12 8TA, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molbiopara.2016.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008435PMC
July 2016

Plasmalogen enrichment in exosomes secreted by a nematode parasite versus those derived from its mouse host: implications for exosome stability and biology.

J Extracell Vesicles 2016 5;5:30741. Epub 2016 Jul 5.

Institute of Immunology and Infection Research and Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, UK;

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937767PMC
http://dx.doi.org/10.3402/jev.v5.30741DOI Listing
July 2016

Novel O-linked methylated glycan antigens decorate secreted immunodominant glycoproteins from the intestinal nematode Heligmosomoides polygyrus.

Int J Parasitol 2016 Mar 12;46(3):157-170. Epub 2015 Dec 12.

Department of Parasitology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2015.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776704PMC
March 2016

TGF-β in tolerance, development and regulation of immunity.

Cell Immunol 2016 Jan 23;299:14-22. Epub 2015 Nov 23.

Institute of Immunology and Infection Research, University of Edinburgh, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellimm.2015.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711336PMC
January 2016

Suppression of OVA-alum induced allergy by Heligmosomoides polygyrus products is MyD88-, TRIF-, regulatory T- and B cell-independent, but is associated with reduced innate lymphoid cell activation.

Exp Parasitol 2015 Nov 26;158:8-17. Epub 2015 Feb 26.

Institute of Immunology and Infection Research, and Centre for Immunity, Infection and Evolution, School of Biological Sciences, Ashworth Laboratories, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2015.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485390PMC
November 2015

Cohabitation in the Intestine: Interactions among Helminth Parasites, Bacterial Microbiota, and Host Immunity.

J Immunol 2015 Nov;195(9):4059-66

Centre for Immunity, Infection, and Evolution, Institute of Immunology and Infection Research, Ashworth Laboratories, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1501432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617609PMC
November 2015

Schistosoma mansoni Larvae Do Not Expand or Activate Foxp3+ Regulatory T Cells during Their Migratory Phase.

Infect Immun 2015 Oct 20;83(10):3881-9. Epub 2015 Jul 20.

Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/IAI.00408-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567639PMC
October 2015

Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections.

Trends Parasitol 2015 Oct;31(10):477-489

Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK; Centre for Immunity, Infection, and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S14714922150014
Publisher Site
http://dx.doi.org/10.1016/j.pt.2015.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685040PMC
October 2015

CCR7-dependent trafficking of RORγ⁺ ILCs creates a unique microenvironment within mucosal draining lymph nodes.

Nat Commun 2015 Jan 9;6:5862. Epub 2015 Jan 9.

MRC Centre for Immune Regulation, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms6862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354100PMC
January 2015

Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage.

Nat Immunol 2014 Dec 19;15(12):1116-25. Epub 2014 Oct 19.

Institute of Immunology and Infection Research, Centre for Immunity Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.3023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338525PMC
December 2014

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.

Nat Commun 2014 Nov 25;5:5488. Epub 2014 Nov 25.

1] Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK [2] Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms6488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263141PMC
November 2014

Secreted proteomes of different developmental stages of the gastrointestinal nematode Nippostrongylus brasiliensis.

Mol Cell Proteomics 2014 Oct 3;13(10):2736-51. Epub 2014 Jul 3.

From the ‡Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute for Tropical Health and Medicine, James Cook University, Cairns, Queensland, Australia;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.M114.038950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188999PMC
October 2014

MyD88 signaling inhibits protective immunity to the gastrointestinal helminth parasite Heligmosomoides polygyrus.

J Immunol 2014 Sep 11;193(6):2984-93. Epub 2014 Aug 11.

Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, EH9 3JT, United Kingdom; Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh, EH9 3JT, United Kingdom;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1401056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157852PMC
September 2014

Immunology. How helminths go viral.

Science 2014 Aug 31;345(6196):517-8. Epub 2014 Jul 31.

Center for Immunity and Inflammation,Department of Medicine, New Jersey Medical School,Rutgers-the State University of New Jersey, Newark, NJ, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1258443DOI Listing
August 2014

MHC-II: a mutual support system for ILCs and T cells?

Immunity 2014 Aug;41(2):174-6

MRC Centre for Immune Regulation, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, West Midlands B15 2TT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2014.07.006DOI Listing
August 2014

Commensal-pathogen interactions in the intestinal tract: lactobacilli promote infection with, and are promoted by, helminth parasites.

Gut Microbes 2014 Jul 5;5(4):522-32. Epub 2014 Aug 5.

Centre for Immunity, Infection and Evolution, and Institute of Immunology and Infection Research; Ashworth Laboratories; University of Edinburgh; Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/gmic.32155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822684PMC
July 2014

Vaccination against helminth parasite infections.

Expert Rev Vaccines 2014 Apr;13(4):473-87

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/14760584.2014.893195DOI Listing
April 2014

Inflammatory Bowel Disease.

Evol Med Public Health 2014 22;2014(1):95. Epub 2014 Apr 22.

Centre for African Studies, University of Edinburgh.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/emph/eou017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204624PMC
April 2014

The secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivo.

PLoS Pathog 2014 Feb 27;10(2):e1003930. Epub 2014 Feb 27.

Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1003930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937304PMC
February 2014

Helminths and immunological tolerance.

Transplantation 2014 Jan;97(2):127-32

1 Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, UK. 2 MRC Centre for Inflammation Research, University of Edinburgh, Queens Medical Research Institute, Edinburgh, UK. 3 Address correspondence to: Rick M. Maizels, Institute of Immunology and Infection Research, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/TP.0b013e3182a53f59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940291PMC
January 2014

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo.

Eur J Immunol 2014 Jan 4;44(1):150-61. Epub 2013 Nov 4.

Institute of Immunology and Infection Research, University of Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201343746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992848PMC
January 2014

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1.

J Exp Med 2013 Oct 7;210(11):2477-91. Epub 2013 Oct 7.

Institute of Immunology and Infection Research, School of Biological Sciences; and 2 Medical Research Council Centre for Inflammation Research and 3 The Roslin Institute and Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary Medicine; University of Edinburgh, Edinburgh EH8 9YL, Scotland, UK.

View Article

Download full-text PDF

Source
http://www.jem.org/lookup/doi/10.1084/jem.20121999
Publisher Site
http://dx.doi.org/10.1084/jem.20121999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804948PMC
October 2013

Into the wild: digging at immunology's evolutionary roots.

Nat Immunol 2013 Sep;14(9):879-83

Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.2643DOI Listing
September 2013

Gain of function in the immune system caused by a ryanodine receptor 1 mutation.

J Cell Sci 2013 Aug 23;126(Pt 15):3485-92. Epub 2013 May 23.

Departments of Anaesthesia and Biomedicine, Basel University Hospital, Hebelstrasse 20, 4031 Basel, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.130310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730249PMC
August 2013

Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity.

PLoS Pathog 2013 Aug 15;9(8):e1003492. Epub 2013 Aug 15.

Institute of Immunology and Infection Research, Ashworth Laboratories, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1003492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744408PMC
August 2013

Toxocara canis: molecular basis of immune recognition and evasion.

Authors:
Rick M Maizels

Vet Parasitol 2013 Apr 20;193(4):365-74. Epub 2012 Dec 20.

Institute of Immunology and Infection Research, University of Edinburgh, Ashworth Laboratories, West Mains Road, Edinburgh EH9 3JT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2012.12.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611597PMC
April 2013

Immunomodulation by helminth parasites: defining mechanisms and mediators.

Int J Parasitol 2013 Mar 3;43(3-4):301-10. Epub 2013 Jan 3.

Institute of Immunology and Infection Research, University of Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2012.11.011DOI Listing
March 2013

ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection.

Eur J Immunol 2013 Mar 31;43(3):705-15. Epub 2013 Jan 31.

Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201242794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615169PMC
March 2013

Prevention of birch pollen-related food allergy by mucosal treatment with multi-allergen-chimers in mice.

PLoS One 2012 29;7(6):e39409. Epub 2012 Jun 29.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039409PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387141PMC
November 2012

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus.

Semin Immunopathol 2012 Nov 11;34(6):829-46. Epub 2012 Oct 11.

Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, EH9 3JT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00281-012-0347-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496515PMC
November 2012

Helminth infections and host immune regulation.

Clin Microbiol Rev 2012 Oct;25(4):585-608

Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/CMR.05040-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485755PMC
October 2012

Immune modulation and modulators in Heligmosomoides polygyrus infection.

Exp Parasitol 2012 Sep 22;132(1):76-89. Epub 2011 Aug 22.

Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3JT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2011.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485391PMC
September 2012

Antibodies and IL-3 support helminth-induced basophil expansion.

Proc Natl Acad Sci U S A 2012 Sep 28;109(37):14954-9. Epub 2012 Aug 28.

Institute of Microbiology, Swiss Federal Institute of Technology, 8093 Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1117584109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443190PMC
September 2012

Cutting edge: in the absence of TGF-β signaling in T cells, fewer CD103+ regulatory T cells develop, but exuberant IFN-γ production renders mice more susceptible to helminth infection.

J Immunol 2012 Aug 29;189(3):1113-7. Epub 2012 Jun 29.

Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1200991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428909PMC
August 2012

Susceptibility and immunity to helminth parasites.

Curr Opin Immunol 2012 Aug 12;24(4):459-66. Epub 2012 Jul 12.

Institute of Immunology and Infection Research, University of Edinburgh, UK.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09527915120009
Publisher Site
http://dx.doi.org/10.1016/j.coi.2012.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437973PMC
August 2012

T cells in helminth infection: the regulators and the regulated.

Trends Immunol 2012 Apr 5;33(4):181-9. Epub 2012 Mar 5.

Institute of Immunology and Infection Research, University of Edinburgh, Ashworth Laboratories, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.it.2012.01.001DOI Listing
April 2012

Forum: Immunology: Allergy challenged.

Nature 2012 Apr 25;484(7395):458-9. Epub 2012 Apr 25.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/484458aDOI Listing
April 2012

Regulatory T cells in infection.

Adv Immunol 2011 ;112:73-136

Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-387827-4.00003-6DOI Listing
March 2012

Wild immunology: converging on the real world.

Ann N Y Acad Sci 2011 Oct;1236:17-29

Centre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Ashworth Laboratories, Kings Buildings, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1749-6632.2011.06251.x
Publisher Site
http://dx.doi.org/10.1111/j.1749-6632.2011.06251.xDOI Listing
October 2011

Th2 responses to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITR ligand costimulation in vivo.

J Immunol 2011 Aug 24;187(3):1411-20. Epub 2011 Jun 24.

Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407370PMC
http://dx.doi.org/10.4049/jimmunol.1100834DOI Listing
August 2011

Addendum: Defeating sepsis by misleading MyD88.

Nat Immunol 2011 Jul 19;12(8):804. Epub 2011 Jul 19.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni0811-804bDOI Listing
July 2011

Chronic helminth infection promotes immune regulation in vivo through dominance of CD11cloCD103- dendritic cells.

J Immunol 2011 Jun 16;186(12):7098-109. Epub 2011 May 16.

Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1003636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794626PMC
June 2011

Diversity and dialogue in immunity to helminths.

Nat Rev Immunol 2011 Jun;11(6):375-88

Institute for Immunology and Infection Research, Ashworth Laboratories, University of Edinburgh, UK.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nri2992
Publisher Site
http://dx.doi.org/10.1038/nri2992DOI Listing
June 2011

Schistosome infection intensity is inversely related to auto-reactive antibody levels.

PLoS One 2011 May 6;6(5):e19149. Epub 2011 May 6.

Ashworth Laboratories, School of Biological Sciences, Institute for Immunology and Infection Research, University of Edinburgh, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019149PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089602PMC
May 2011

Analyzing airway inflammation with chemical biology: dissection of acidic mammalian chitinase function with a selective drug-like inhibitor.

Chem Biol 2011 May;18(5):569-79

Centre for Immunity, Infection and Evolution, and the Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Scotland, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chembiol.2011.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115046PMC
May 2011

Defeating sepsis by misleading MyD88.

Nat Immunol 2011 Apr;12(4):284-6

Ashworth Laboratories, Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni0411-284DOI Listing
April 2011

Immunology. Eosinophils forestall obesity.

Science 2011 Apr;332(6026):186-7

Centre for Immunity, Infection and Evolution and the Institute for Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3JT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1205313DOI Listing
April 2011

Heligmosomoides polygyrus: one species still.

Trends Parasitol 2011 Mar 14;27(3):100-1. Epub 2010 Dec 14.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pt.2010.11.004DOI Listing
March 2011

Regulatory and activated T cells in human Schistosoma haematobium infections.

PLoS One 2011 Feb 10;6(2):e16860. Epub 2011 Feb 10.

Ashworth Laboratories, School of Biological Sciences, Institute for Immunology and Infection Research, University of Edinburgh, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016860PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037381PMC
February 2011

Developmental regulation and extracellular release of a VSG expression-site-associated gene product from Trypanosoma brucei bloodstream forms.

J Cell Sci 2010 Oct 7;123(Pt 19):3401-11. Epub 2010 Sep 7.

Centre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, Kings' Buildings, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK.

View Article

Download full-text PDF

Source
http://jcs.biologists.org/cgi/doi/10.1242/jcs.068684
Publisher Site
http://dx.doi.org/10.1242/jcs.068684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939805PMC
October 2010