Richard Weinshilboum

Richard Weinshilboum

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Richard Weinshilboum

Richard Weinshilboum

Publications by authors named "Richard Weinshilboum"

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Pharmacogenomics in Practice.

Clin Pharmacol Ther 2019 Nov 9;106(5):936-938. Epub 2019 Sep 9.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/cpt.1600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857970PMC
November 2019

Systematic review of the evidence on the cost-effectiveness of pharmacogenomics-guided treatment for cardiovascular diseases.

Genet Med 2019 Oct 8. Epub 2019 Oct 8.

Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41436-019-0667-yDOI Listing
October 2019

Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand-Dependent Gene Expression.

Drug Metab Dispos 2019 Sep 10;47(9):983-994. Epub 2019 Jul 10.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (D.R.N., D.L., H.L., L.W., R.M.W.), Epigenomics Program, Center for Individualized Medicine (J.-H.L., T.O.), Division of Experimental Pathology and Laboratory Medicine, Department of Laboratory Medicine and Pathology (J.-H.L.), Division of Biomedical Statistics and Informatics (Z.Y.), Department of Physiology and Biomedical Engineering (T.O.), and Division of Gastroenterology and Hepatology, Department of Medicine (T.O.), Mayo Clinic, Rochester, Minnesota

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http://dx.doi.org/10.1124/dmd.119.087312DOI Listing
September 2019

Catechol O-Methyltransferase Pharmacogenomics: Challenges and Opportunities.

Clin Pharmacol Ther 2019 Aug 13;106(2):281-283. Epub 2019 May 13.

1Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/cpt.1452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663608PMC
August 2019

Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons.

Mol Psychiatry 2019 06 30;24(6):795-807. Epub 2019 Jan 30.

Laboratory of Genetics, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/s41380-019-0363-yDOI Listing
June 2019

Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons.

Mol Psychiatry 2019 06 22;24(6):808-818. Epub 2019 Mar 22.

Laboratory of Genetics, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/s41380-019-0377-5DOI Listing
June 2019

4-Hydroxytamoxifen enhances sensitivity of estrogen receptor α-positive breast cancer to docetaxel in an estrogen and ZNF423 SNP-dependent fashion.

Breast Cancer Res Treat 2019 Jun 1;175(3):567-578. Epub 2019 Apr 1.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/s10549-019-05194-zDOI Listing
June 2019

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall.

Oncotarget 2019 Jun 11;10(39):3924-3930. Epub 2019 Jun 11.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.18632/oncotarget.27001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570466PMC
June 2019

Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in and .

Drug Metab Dispos 2019 04 11;47(4):425-435. Epub 2019 Feb 11.

Departments of Molecular Pharmacology and Experimental Therapeutics (S.D., I.M., M.-F.H., L.W., R.M.W., J.M.R.) and Health Sciences Research (N.B.L., S.J.B.), Personalized Genomics Laboratory, Department of Laboratory Medicine and Pathology (A.M.M., J.L.B.), and Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Graduate School of Biomedical Sciences (D.R.N.), Mayo Clinic, Rochester, Minnesota; and Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas (S.E.S.)

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http://dx.doi.org/10.1124/dmd.118.084269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423619PMC
April 2019

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1.

Breast Cancer Res 2019 04 3;21(1):47. Epub 2019 Apr 3.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1186/s13058-019-1130-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448248PMC
April 2019

The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer.

Cancer Metab 2019 24;7. Epub 2019 Jan 24.

1Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905 USA.

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http://dx.doi.org/10.1186/s40170-018-0193-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345044PMC
January 2019

The Role of the Aryl Hydrocarbon Receptor (AHR) in Immune and Inflammatory Diseases.

Int J Mol Sci 2018 Dec 3;19(12). Epub 2018 Dec 3.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55902, USA.

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http://www.mdpi.com/1422-0067/19/12/3851
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http://dx.doi.org/10.3390/ijms19123851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321643PMC
December 2018

Single Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 Induction.

Drug Metab Dispos 2018 09 6;46(9):1372-1381. Epub 2018 Jul 6.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (D.L., S.Q., B.R., L.W., R.M.W.) and Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.K.), Mayo Clinic, Rochester, Minnesota

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http://dx.doi.org/10.1124/dmd.118.082164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090174PMC
September 2018

SLCO1B1 genetic variation and hormone therapy in menopausal women.

Menopause 2018 08;25(8):877-882

Departments of Surgery and Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/GME.0000000000001109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092108PMC
August 2018

BRCA1/2 Mutations and Bevacizumab in the Neoadjuvant Treatment of Breast Cancer: Response and Prognosis Results in Patients With Triple-Negative Breast Cancer From the GeparQuinto Study.

J Clin Oncol 2018 08 23;36(22):2281-2287. Epub 2018 May 23.

Peter A. Fasching and Matthias Rübner, Erlangen University Hospital, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen; Sibylle Loibl, Valentina Nekljudova, Karsten E. Weber, and Gunter von Minckwitz, German Breast Group Forschungs, Neu-Isenburg; Christian Schem, University Medical Center Schleswig-Holstein, Kiel; Hans Tesch, Centrum für Hämatologie und Onkologie Bethanien, Frankfurt; Michael Untch, Helios-Klinikum, Berlin-Buch; Jörn Hilfrich, Eilenriede-Klinik, Hannover; Mahdi Rezai, Luisenkrankenhaus; Tanja Fehm, Düsseldorf University Hospital, Heinrich-Heine University of Düsseldorf, Düsseldorf; Bernd Gerber, University of Rostock, Rostock; Serban Dan Costa, Magdeburg University Hospital, Magdeburg; Jens-Uwe Blohmer and Cornelia Liedtke, Charité University Hospital Campus Charité-Mitte, Berlin; Jens Huober, University of Ulm; Brigitte Rack, University Hospital Ulm, Ulm; Volkmar Müller, Hamburg University Hospital, Hamburg, Germany; Chunling Hu, Steven N. Hart, Hermela Shimelis, Raymond Moore, James N. Ingle, and Fergus J. Couch, Mayo Clinic; and Richard M. Weinshilboum and Liewei Wang, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN.

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http://ascopubs.org/doi/10.1200/JCO.2017.77.2285
Publisher Site
http://dx.doi.org/10.1200/JCO.2017.77.2285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067803PMC
August 2018

, a Novel Transcription Factor and a Coregulator of Nuclear Factor B p65: Single Nucleotide Polymorphism and Estrogen Dependence.

J Pharmacol Exp Ther 2018 06 28;365(3):700-710. Epub 2018 Mar 28.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (M.H., E.L.d.R., C.Z., L.W., H.L., R.M.W.), and Division of Medical Oncology, Department of Oncology (J.N.I.), Mayo Clinic, Rochester, Minnesota; Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, Massachusetts (P.E.G.); Canadian Cancer Trials Group, Kingston, Ontario, Canada (L.E.S.); and RIKEN Center for Integrative Medical Science, Yokohama, Japan (M.K.)

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http://dx.doi.org/10.1124/jpet.118.247718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954488PMC
June 2018

Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression.

Biochem Pharmacol 2018 06 3;152:279-292. Epub 2018 Apr 3.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.03.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960634PMC
June 2018

Benefits of and Barriers to Pharmacogenomics-Guided Treatment for Major Depressive Disorder.

Clin Pharmacol Ther 2018 05 1;103(5):767-769. Epub 2018 Feb 1.

Department of Psychiatry and Psychology and Mayo Clinic Depression Center, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/cpt.1009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380658PMC
May 2018

Pharmacogenomic Discovery to Function and Mechanism: Breast Cancer as a Case Study.

Clin Pharmacol Ther 2018 02 1;103(2):243-252. Epub 2017 Dec 1.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/cpt.915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760458PMC
February 2018

Pharmacogenomics: Precision Medicine and Drug Response.

Mayo Clin Proc 2017 11 1;92(11):1711-1722. Epub 2017 Nov 1.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2017.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682947PMC
November 2017

SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1.

PLoS Genet 2017 Oct 2;13(10):e1007031. Epub 2017 Oct 2.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638617PMC
October 2017

Single-Nucleotide Polymorphisms and Estrogen-Mediated Toll-Like Receptor-MYD88-Dependent Nuclear Factor-B Activation: Single-Nucleotide Polymorphism- and Selective Estrogen Receptor Modulator-Dependent Modification of Inflammation and Immune Response.

Mol Pharmacol 2017 08 14;92(2):175-184. Epub 2017 Jun 14.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (M.-F.H., L.W., R.M.W.), Division of Medical Oncology, Department of Oncology (J.N.I.), and Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.K.), Mayo Clinic, Rochester, Minnesota; Department of Emergency Medicine, Vanderbilt Medical Center, Nashville, Tennessee (T.B.); Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, Massachusetts (P.E.G.); NCIC Clinical Trials Group, Kingston, Ontario Canada (L.E.S.); and RIKEN Center for Integrative Medical Science, Tsurumi-ku, Yokohama, Japan (T.M., M.K.)

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http://molpharm.aspetjournals.org/lookup/doi/10.1124/mol.117
Publisher Site
http://dx.doi.org/10.1124/mol.117.108340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508195PMC
August 2017

Immune Mediator Pharmacogenomics: SNPs and Estrogen-Dependent Regulation of Inflammation.

J Nat Sci 2017 Aug;3(8)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578609PMC
August 2017

Genome-wide association studies of drug response and toxicity: an opportunity for genome medicine.

Nat Rev Drug Discov 2017 Jan 25;16(1). Epub 2016 Nov 25.

RIKEN Center for Integrative Medical Science, Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1038/nrd.2016.234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443656PMC
January 2017

Using EHR-Linked Biobank Data to Study Metformin Pharmacogenomics.

Stud Health Technol Inform 2015 ;210:914-8

Mayo Clinic, Department of Health of Sciences Research.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051541PMC
November 2016

A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes.

Sci Rep 2016 11 14;6:37003. Epub 2016 Nov 14.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1038/srep37003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107984PMC
November 2016

Influence of SULT1A1 genetic variation on age at menopause, estrogen levels, and response to hormone therapy in recently postmenopausal white women.

Menopause 2016 08;23(8):863-9

1Department of Laboratory Medicine and Pathology 2Division of Biomedical Statistics and Informatics 3Department of Molecular Pharmacology and Experimental Therapeutics 4Departments of Surgery and Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/GME.0000000000000648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961269PMC
August 2016

Combined Effects of Acamprosate and Escitalopram on Ethanol Consumption in Mice.

Alcohol Clin Exp Res 2016 07 17;40(7):1531-9. Epub 2016 May 17.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, College of Medicine, Rochester, Minnesota.

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http://dx.doi.org/10.1111/acer.13099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020905PMC
July 2016

Pharmacometabolomics informs Pharmacogenomics.

Metabolomics 2016 Jul 1;12(7). Epub 2016 Jul 1.

Department of Molecular Pharmacology and Experimental Therapeutics, 200 First Street SW, Mayo Clinic, Rochester, MN 55905.

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http://dx.doi.org/10.1007/s11306-016-1066-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976774PMC
July 2016

Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation.

Mol Endocrinol 2016 Mar 11;30(3):382-98. Epub 2016 Feb 11.

Division of Clinical Pharmacology (M.-F.H., M.L., L.W., R.M.W.), Department of Molecular Pharmacology and Experimental Therapeutics, Division of Rheumatology (M.-F.H., T.B.), Department of Medicine, Division of Biomedical Statistics and Informatics (K.R.K.), Department of Health Sciences Research, and Division of Medical Oncology (M.P.G., J.N.I.), Department of Oncology, Mayo Clinic, Rochester, Minnesota 55905; Division of Hematology/Oncology (P.E.G.), Department of Medicine, Massachusetts General Hospital Cancer Center, Harvard University, Boston, Massachusetts 02114; National Cancer Institute of Canada Clinical Trials Group (L.E.S.), Kingston, Ontario, Canada K7L 3N6; and RIKEN Center for Integrative Medical Science (M.K.), Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1210/me.2015-1267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771694PMC
March 2016

KnowEnG: a knowledge engine for genomics.

J Am Med Inform Assoc 2015 Nov 23;22(6):1115-9. Epub 2015 Jul 23.

Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL, USA Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

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http://dx.doi.org/10.1093/jamia/ocv090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009907PMC
November 2015

Accuracy of Electronic Medical Record Medication Reconciliation in Emergency Department Patients.

J Emerg Med 2015 Jul 19;49(1):78-84. Epub 2015 Mar 19.

Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado; Rocky Mountain Poison & Drug Center, Denver, Colorado.

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http://dx.doi.org/10.1016/j.jemermed.2014.12.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476907PMC
July 2015

Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites.

Circ Cardiovasc Genet 2015 Feb 1;8(1):141-9. Epub 2014 Dec 1.

From the Division of Cardiovascular Diseases, Department of Internal Medicine (N.L.P., T.M.O., R.J.R., M.M.R., J.C.B.), Department of Biomedical Statistics and Informatics (N.T., C.G.S, G.D.J., N.P.), and Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (N.L.P., R.M.W.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1161/CIRCGENETICS.114.000624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387792PMC
February 2015

Electrophysiological Neuroimaging using sLORETA Comparing 22 Age Matched Male and Female Schizophrenia Patients.

Hosp Chron 2015;10(2):91-98

Department of Molecular Pharmacology and Experimental Therapeutics, Division of Clinical Pharmacology, Gonda 19, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662405PMC
January 2015

Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.

Mol Endocrinol 2014 Oct 22;28(10):1740-51. Epub 2014 Aug 22.

Division of Clinical Pharmacology (M.L., L.W., R.M.W.), Department of Molecular Pharmacology and Experimental Therapeutics; Departments of Oncology (J.N.I.) and Health Sciences Research (A.B., G.D.J., E.E.C., D.J.S.); and Division of Endocrinology (S.K.), Mayo Clinic, Rochester, Minnesota 55905; Massachusetts General Hospital (P.E.G.), Harvard University, Boston, Massachusetts 02114; Rikagaku Kenkyūsho Center for Integrative Medical Science (M.K., Y.F.), Yokohama, Japan 230-0045; School of Medicine (Y.N.), Chicago University, Chicago, Illinois 60637; National Cancer Institute of Canada Clinical Trials Group (J.-A.W.C., L.E.S.), Kingston, Ontario, Canada K7L 3N6; and Division of Oncology (M.J.E.), Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110.

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http://dx.doi.org/10.1210/me.2014-1147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179631PMC
October 2014

Metformin pharmacogenomics: biomarkers to mechanisms.

Diabetes 2014 Aug;63(8):2609-10

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Mayo Clinic College of Medicine, Rochester, MN

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http://dx.doi.org/10.2337/db14-0609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113071PMC
August 2014

The effect of CYP2D6 drug-drug interactions on hydrocodone effectiveness.

Acad Emerg Med 2014 Aug 24;21(8):879-85. Epub 2014 Aug 24.

Department of Emergency Medicine, University of Colorado, Aurora, CO; Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA; Rocky Mountain Poison & Drug Center, Denver, CO.

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http://dx.doi.org/10.1111/acem.12431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150819PMC
August 2014

Treatment outcomes of depression: the pharmacogenomic research network antidepressant medication pharmacogenomic study.

J Clin Psychopharmacol 2014 Jun;34(3):313-7

From the Departments of *Psychiatry and Psychology, and †Health Sciences Research, Mayo Clinic, Rochester, MN; ‡Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York Presbyterian-Allen Hospital, New York, NY; §US Department of Defense, Department of Behavioral Health, Heidelberg, Germany; ∥Department of Psychiatry, Roy J. and Lucille A. Carver College of Medicine University of Iowa Hospitals and Clinics, Iowa, IA; and Departments of ¶Information Technology, and #Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/JCP.0000000000000099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992481PMC
June 2014

Re: Concordance between CYP2D6 genotypes obtained from tumor-derived and germline DNA.

J Natl Cancer Inst 2014 Apr 3;106(5). Epub 2014 Apr 3.

Affiliations of authors: Department of Oncology (MPG, JNI) and Department of Molecular Pharmacology and Experimental Therapeutics (MPG, RW), Mayo Clinic, Rochester, MN; Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany (HB); The University of Chicago, Chicago, IL (MJR, NJC, YN).

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http://dx.doi.org/10.1093/jnci/dju063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580553PMC
April 2014

Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes.

Pharmacogenomics 2014 Mar;15(4):433-47

Division of Clinical Pharmacology, Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.2217/pgs.13.226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027966PMC
March 2014