Publications by authors named "Richard S Mann"

100Publications

A size principle for recruitment of leg motor neurons.

Elife 2020 06 3;9. Epub 2020 Jun 3.

Department of Physiology and Biophysics, University of Washington, Seattle, United States.

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June 2020

Control of tissue morphogenesis by the HOX gene .

Development 2020 03 2;147(5). Epub 2020 Mar 2.

Epithelial Biology Laboratory, The Francis Crick Institute, 1 Midland Rd, St Pancras, London NW1 1AT, United Kingdom

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March 2020

Context-Dependent Gene Regulation by Homeodomain Transcription Factor Complexes Revealed by Shape-Readout Deficient Proteins.

Mol Cell 2020 04 12;78(1):152-167.e11. Epub 2020 Feb 12.

Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Biochemistry and Molecular Biophysics, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA; Department of Neuroscience, Columbia University, New York, NY 10027, USA. Electronic address:

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April 2020

Serotonergic Modulation of Walking in Drosophila.

Curr Biol 2019 12 27;29(24):4218-4230.e8. Epub 2019 Nov 27.

Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA; Departments of Biochemistry and Molecular Biophysics and Neuroscience, Columbia University, New York, NY 10027, USA. Electronic address:

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December 2019

Toward a Mechanistic Understanding of DNA Methylation Readout by Transcription Factors.

J Mol Biol 2019 Nov 2. Epub 2019 Nov 2.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA; Department of Systems Biology, Columbia University, New York, NY 10032, USA. Electronic address:

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November 2019

Low affinity binding sites in an activating CRM mediate negative autoregulation of the Drosophila Hox gene Ultrabithorax.

PLoS Genet 2019 10 7;15(10):e1008444. Epub 2019 Oct 7.

Department of Biochemistry and Molecular Biophysics and Systems Biology, Columbia University, New York, NY, United States of America.

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October 2019

In vivo Hox binding specificity revealed by systematic changes to a single cis regulatory module.

Nat Commun 2019 08 9;10(1):3597. Epub 2019 Aug 9.

Centro Andaluz de Biología del Desarrollo (CSIC/JA/UPO), Universidad Pablo de Olavide, 41013, Seville, Spain.

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August 2019

Low-Affinity Binding Sites and the Transcription Factor Specificity Paradox in Eukaryotes.

Annu Rev Cell Dev Biol 2019 10 5;35:357-379. Epub 2019 Jul 5.

Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10031, USA; email:

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October 2019

The development and assembly of the Drosophila adult ventral nerve cord.

Curr Opin Neurobiol 2019 06 28;56:135-143. Epub 2019 Feb 28.

Department of Biochemistry and Molecular Biophysics, Department of Neuroscience, Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, United States. Electronic address:

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June 2019

Stereotyped terminal axon branching of leg motor neurons mediated by IgSF proteins DIP-α and Dpr10.

Elife 2019 02 4;8. Epub 2019 Feb 4.

Department of Neuroscience, Mortimer B. Zuckerman Mind Brain Behavior Institute, New York, United States.

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February 2019

TP901-1 Phage Recombinase Facilitates Genome Engineering in .

G3 (Bethesda) 2019 04 9;9(4):983-986. Epub 2019 Apr 9.

Department of Biochemistry and Molecular Biophysics and Systems Biology, Columbia University, Zuckerman Mind Brain Behavior Institute, 3227 Broadway, Quad 9A, New York, NY 10027

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April 2019

Visualize Drosophila Leg Motor Neuron Axons Through the Adult Cuticle.

J Vis Exp 2018 10 30(140). Epub 2018 Oct 30.

Institut de Génomique Fonctionnelle de Lyon, ENS de Lyon, CNRS;

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October 2018

Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites.

Cell Rep 2018 08;24(9):2221-2230

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA; Department of Systems Biology, Columbia University, New York, NY, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA. Electronic address:

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August 2018

cis-regulatory architecture of a short-range EGFR organizing center in the Drosophila melanogaster leg.

PLoS Genet 2018 08 24;14(8):e1007568. Epub 2018 Aug 24.

Department of Biochemistry and Molecular Biophysics and Department of Systems Biology, Columbia University, New York, NY, United States of America.

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August 2018

Robust ΦC31-Mediated Genome Engineering in Using Minimal attP/attB Phage Sites.

G3 (Bethesda) 2018 05 4;8(5):1399-1402. Epub 2018 May 4.

Departments of Biochemistry and Molecular Biophysics and Systems Biology, Jerome L. Greene Science Center, Columbia University, New York, NY 10027

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May 2018

Systematic prediction of DNA shape changes due to CpG methylation explains epigenetic effects on protein-DNA binding.

Epigenetics Chromatin 2018 02 6;11(1). Epub 2018 Feb 6.

Computational Biology and Bioinformatics Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA, 90089, USA.

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February 2018

Differing Strategies Despite Shared Lineages of Motor Neurons and Glia to Achieve Robust Development of an Adult Neuropil in Drosophila.

Neuron 2018 02 27;97(3):538-554.e5. Epub 2018 Jan 27.

Departments of Biochemistry and Molecular Biophysics, and Neuroscience, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA. Electronic address:

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February 2018

Origins and Specification of the Drosophila Wing.

Curr Biol 2017 Dec 7;27(24):3826-3836.e5. Epub 2017 Dec 7.

Departamento de Biología Molecular and Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), Nicolás Cabrera 1, 28049 Madrid, Spain. Electronic address:

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December 2017

From Reductionism to Holism: Toward a More Complete View of Development Through Genome Engineering.

Adv Exp Med Biol 2017 ;1016:45-74

Department of Biochemistry and Molecular Biophysics and Systems Biology, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, 612 West 130th Street, 9th Floor, New York, NY, 10027, USA.

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April 2018

Genome-wide prediction of minor-groove electrostatic potential enables biophysical modeling of protein-DNA binding.

Nucleic Acids Res 2017 Dec;45(21):12565-12576

Computational Biology and Bioinformatics Program, Departments of Biological Sciences, Chemistry, Physics & Astronomy, and Computer Science, University of Southern California, Los Angeles, CA 90089, USA.

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December 2017

Quantitative Analysis of the DNA Methylation Sensitivity of Transcription Factor Complexes.

Cell Rep 2017 06;19(11):2383-2395

Department of Biological Sciences, Columbia University, New York, NY 10027, USA; Department of Systems Biology, Columbia University Medical Center, New York, NY 10032, USA. Electronic address:

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June 2017

Bxb1 phage recombinase assists genome engineering in .

Biotechniques 2017 01 1;62(1):37-38. Epub 2017 Jan 1.

Departments of Biochemistry and Molecular Biophysics and Systems Biology, Columbia University, New York, NY.

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January 2017

To Be Specific or Not: The Critical Relationship Between Hox And TALE Proteins.

Trends Genet 2016 06 8;32(6):334-347. Epub 2016 Apr 8.

Columbia University Medical Center, New York, NY, USA. Electronic address:

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June 2016

Streamlined scanning for enhancer elements in Drosophila melanogaster.

Biotechniques 2016 1;60(3):141-4. Epub 2016 Mar 1.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY.

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June 2017

The Importance of Timing.

Cell 2016 Jan;164(3):347-8

Department of Biochemistry and Molecular Biophysics, Zuckerman Mind Brain Behavior Institute, Medical Scientist Training Program, Columbia University, New York, NY 10027, USA.

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January 2016

Building accurate sequence-to-affinity models from high-throughput in vitro protein-DNA binding data using FeatureREDUCE.

Elife 2015 Dec 23;4. Epub 2015 Dec 23.

Department of Biological Sciences, Columbia University, New York, United States.

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December 2015

How Genomes Generate Animals: A View from Pasadena Genomic Control Process: Development and Evolution.

Authors:
Richard S Mann

FASEB J 2015 Dec;29(12):4764-4765

Department of Biochemistry and Molecular Biophysics and Department of Systems Biology, Columbia University, New York, New York.

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December 2015

Asparagine deamidation reduces DNA-binding affinity of the Drosophila melanogaster Scr homeodomain.

FEBS Lett 2015 Oct 3;589(21):3237-41. Epub 2015 Oct 3.

Department of Biochemistry and Molecular Biophysics, Columbia University, 630 West 168th Street, New York, NY 10032, United States. Electronic address:

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October 2015

Quantification of gait parameters in freely walking rodents.

BMC Biol 2015 Jul 22;13:50. Epub 2015 Jul 22.

Department of Biochemistry and Molecular Biophysics, Columbia University, 701 West 168th Street, HHSC 1104, New York, NY, 10032, USA.

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July 2015

Specification of individual adult motor neuron morphologies by combinatorial transcription factor codes.

Neuron 2015 May 7;86(4):955-970. Epub 2015 May 7.

Department of Biochemistry and Molecular Biophysics, Columbia University, HHSC 1108, 701 W. 168(th) Street, New York, NY 10032, USA. Electronic address:

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May 2015

Deconvolving the recognition of DNA shape from sequence.

Cell 2015 Apr 2;161(2):307-18. Epub 2015 Apr 2.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA; Department of Systems Biology, Columbia University, New York, NY 10032, USA. Electronic address:

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April 2015

Quantitative modeling of transcription factor binding specificities using DNA shape.

Proc Natl Acad Sci U S A 2015 Apr 9;112(15):4654-9. Epub 2015 Mar 9.

Molecular and Computational Biology Program, Departments of Biological Sciences, Chemistry, Physics, and Computer Science, University of Southern California, Los Angeles, CA 90089;

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April 2015

Swept confocally-aligned planar excitation (SCAPE) microscopy for high speed volumetric imaging of behaving organisms.

Nat Photonics 2015 Feb;9(2):113-119

Laboratory for Functional Optical Imaging, Departments of Biomedical Engineering and Radiology, Columbia University, New York, NY 10027.

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February 2015

Low affinity binding site clusters confer hox specificity and regulatory robustness.

Cell 2015 Jan 31;160(1-2):191-203. Epub 2014 Dec 31.

Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA. Electronic address:

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January 2015

Kinematic responses to changes in walking orientation and gravitational load in Drosophila melanogaster.

PLoS One 2014 28;9(10):e109204. Epub 2014 Oct 28.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America.

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June 2015

cgChIP: a cell type- and gene-specific method for chromatin analysis.

Methods Mol Biol 2014 ;1196:291-306

Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, HHSC 1104, 701 West 168th Street, New York, NY, 10032, USA.

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May 2015

SELEX-seq: a method for characterizing the complete repertoire of binding site preferences for transcription factor complexes.

Methods Mol Biol 2014 ;1196:255-78

Department of Biological Sciences, Columbia University, 1212 Amsterdam Avenue, MC 2441, New York, NY, 10027, USA.

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May 2015

Yorkie promotes transcription by recruiting a histone methyltransferase complex.

Cell Rep 2014 Jul 10;8(2):449-59. Epub 2014 Jul 10.

Howard Hughes Medical Institute, Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA. Electronic address:

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July 2014

Neuroscience. The Michael Jackson fly.

Authors:
Richard S Mann

Science 2014 Apr;344(6179):48-9

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.

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April 2014

OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites.

Nucleic Acids Res 2014 Jan 22;42(Database issue):D167-71. Epub 2013 Nov 22.

Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Department of Systems Biology, Center for Computational Biology and Bioinformatics, Columbia University, 1130 St. Nicholas Avenue, New York, NY 10032, USA, Department of Life Science, Open University of Israel, Ra'anana 43107, Israel and Department of Biochemistry and Molecular Biophysics, Columbia University, 701 West 168th Street, HHSC 1104, New York, NY 10032, USA.

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January 2014

Divergent transcriptional regulatory logic at the intersection of tissue growth and developmental patterning.

PLoS Genet 2013 5;9(9):e1003753. Epub 2013 Sep 5.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America ; Institute for Genomics and Systems Biology and Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

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March 2014

Dual role for Hox genes and Hox co-factors in conferring leg motoneuron survival and identity in Drosophila.

Development 2013 May 27;140(9):2027-38. Epub 2013 Mar 27.

Department of Biological Sciences, Columbia University, 701 W. 168th Street, New York, NY 10032, USA.

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May 2013

Genome-wide association of Yorkie with chromatin and chromatin-remodeling complexes.

Cell Rep 2013 Feb 8;3(2):309-18. Epub 2013 Feb 8.

Howard Hughes Medical Institute, Waksman Institute, and Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA.

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February 2013

Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster.

Elife 2013 Jan 8;2:e00231. Epub 2013 Jan 8.

Department of Biochemistry and Molecular Biophysics , Columbia University , New York , USA.

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January 2013

A survey of 6,300 genomic fragments for cis-regulatory activity in the imaginal discs of Drosophila melanogaster.

Cell Rep 2012 Oct 12;2(4):1014-24. Epub 2012 Oct 12.

Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, 701 W. 168th Street, HHSC 1104, New York, NY 10032, USA.

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October 2012

Disentangling the many layers of eukaryotic transcriptional regulation.

Annu Rev Genet 2012 28;46:43-68. Epub 2012 Aug 28.

Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

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April 2013

Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired.

Dev Biol 2012 Jun 20;366(2):382-92. Epub 2012 Apr 20.

Department of Biochemistry and Molecular Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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June 2012

Developmental regulation of chromatin conformation by Hox proteins in Drosophila.

Cell Rep 2012 Apr;1(4):350-9

Department of Biochemistry and Molecular Biophysics, Columbia University, 701 W. 168th Street, HHSC 1104, New York, NY 10032, USA.

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April 2012

A dynamic network of morphogens and transcription factors patterns the fly leg.

Curr Top Dev Biol 2012 ;98:173-98

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, USA.

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April 2012

Variable motif utilization in homeotic selector (Hox)-cofactor complex formation controls specificity.

Proc Natl Acad Sci U S A 2011 Dec 12;108(52):21122-7. Epub 2011 Dec 12.

Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA.

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December 2011

Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins.

Cell 2011 Dec;147(6):1270-82

Department of Biochemistry and Molecular Biophysics, Columbia University, 701 West 168(th) Street, HHSC 1104, New York, NY 10032, USA.

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December 2011

Competition for cofactor-dependent DNA binding underlies Hox phenotypic suppression.

Genes Dev 2011 Nov;25(22):2327-32

Department of Neuroscience, College of Physicians and Surgeons, Columbia University, New York 10032, USA.

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November 2011

Establishment of medial fates along the proximodistal axis of the Drosophila leg through direct activation of dachshund by Distalless.

Dev Cell 2011 Apr;20(4):455-68

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.

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April 2011

Genome-wide tissue-specific occupancy of the Hox protein Ultrabithorax and Hox cofactor Homothorax in Drosophila.

PLoS One 2011 Apr 5;6(4):e14686. Epub 2011 Apr 5.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America.

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April 2011

Non-redundant selector and growth-promoting functions of two sister genes, buttonhead and Sp1, in Drosophila leg development.

PLoS Genet 2010 Jun 24;6(6):e1001001. Epub 2010 Jun 24.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America.

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June 2010

A new chisel for sculpting Darwin's endless forms.

Nat Cell Biol 2010 Jun;12(6):528-9

Laboratory of Neurogenetics and Behavior, The Rockefeller University, New York, New York, USA.

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June 2010

Origins of specificity in protein-DNA recognition.

Annu Rev Biochem 2010 ;79:233-69

Howard Hughes Medical Institute, Center for Computational Biology and Bioinformatics, Columbia University, New York, NY 10032, USA.

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June 2010

Electrostatic interactions between arginines and the minor groove in the nucleosome.

J Biomol Struct Dyn 2010 Jun;27(6):861-6

Howard Hughes Medical Institute, Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biophysics, Columbia University, 1130 St. Nicholas Avenue, New York, NY 10032, USA.

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June 2010

The role of DNA shape in protein-DNA recognition.

Nature 2009 Oct;461(7268):1248-53

Howard Hughes Medical Institute, Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biophysics, Columbia University, 1130 Saint Nicholas Avenue, New York, New York 10032, USA.

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October 2009

Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc.

Genes Dev 2009 Oct 17;23(19):2307-19. Epub 2009 Sep 17.

Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, New York, New York 10032, USA.

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October 2009

Regulation of Ubx expression by epigenetic enhancer silencing in response to Ubx levels and genetic variation.

PLoS Genet 2009 Sep 4;5(9):e1000633. Epub 2009 Sep 4.

Department of Biological Sciences, Columbia University, New York, New York, United States of America.

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September 2009

Hox specificity unique roles for cofactors and collaborators.

Curr Top Dev Biol 2009 ;88:63-101

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

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September 2009

Lineage and birth date specify motor neuron targeting and dendritic architecture in adult Drosophila.

J Neurosci 2009 May;29(21):6904-16

Department of Biological Sciences, Columbia University, New York, New York 10032, USA.

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May 2009

The origins of the Drosophila leg revealed by the cis-regulatory architecture of the Distalless gene.

Development 2009 Jan 26;136(1):61-71. Epub 2008 Nov 26.

Department of Biochemistry and Molecular Biophysics, Integrated Program in Cellular, Molecular, Structural and Genetic Studies, Columbia University, 701 W. 168th Street, HHSC 1104, New York, NY 10032, USA.

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January 2009

The control of size in animals: insights from selector genes.

Bioessays 2008 Sep;30(9):843-53

Laboratory of Neurogenetics and Behavior, The Rockefeller University, New York, NY, USA.

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September 2008

A lexicon for homeodomain-DNA recognition.

Cell 2008 Jun;133(7):1133-5

Growth and Development, Biozentrum der Universität Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland.

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June 2008

Molecular integration of wingless, decapentaplegic, and autoregulatory inputs into Distalless during Drosophila leg development.

Dev Cell 2008 Jan;14(1):86-96

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.

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January 2008

Logic of Wg and Dpp induction of distal and medial fates in the Drosophila leg.

Development 2008 Feb 9;135(4):627-36. Epub 2008 Jan 9.

Department of Biochemistry and Molecular Biophysics, Columbia University, 701 West 168th Street, HHSC 1104, New York, NY 10032, USA.

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February 2008

Compartmental modulation of abdominal Hox expression by engrailed and sloppy-paired patterns the fly ectoderm.

Dev Biol 2007 Aug 24;308(2):593-605. Epub 2007 May 24.

Division of Developmental Biology, Cincinnati Children's Hospital, 3333 Burnet Ave, MLC 7007, Cincinnati, OH 45229, USA.

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August 2007

Discovering transcriptional regulatory regions in Drosophila by a nonalignment method for phylogenetic footprinting.

Proc Natl Acad Sci U S A 2007 Apr 29;104(15):6305-10. Epub 2007 Mar 29.

Howard Hughes Medical Institute, Columbia University, New York, NY 10032, USA.

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April 2007

Nubbin and Teashirt mark barriers to clonal growth along the proximal-distal axis of the Drosophila wing.

Dev Biol 2007 Apr 24;304(2):745-58. Epub 2007 Jan 24.

Department of Biological Sciences, Columbia University, 701 West 168th Street, HHSC 1104, New York, NY 10032, USA.

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April 2007

A balance between two nuclear localization sequences and a nuclear export sequence governs extradenticle subcellular localization.

Genetics 2007 Apr 4;175(4):1625-36. Epub 2007 Feb 4.

Department of Genetics and Development, Columbia University, New York, New York 10032, USA.

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April 2007

Hox control of morphogen mobility and organ development through regulation of glypican expression.

Development 2007 Jan 13;134(2):327-34. Epub 2006 Dec 13.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

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January 2007

Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax.

Genes Dev 2006 Jun;20(12):1636-50

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA.

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June 2006

Hox control of organ size by regulation of morphogen production and mobility.

Science 2006 Jul 1;313(5783):63-8. Epub 2006 Jun 1.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

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July 2006

jing is required for wing development and to establish the proximo-distal axis of the leg in Drosophila melanogaster.

Genetics 2006 May 1;173(1):255-66. Epub 2006 Mar 1.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA.

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May 2006

Evidence that nervy, the Drosophila homolog of ETO/MTG8, promotes mechanosensory organ development by enhancing Notch signaling.

Dev Biol 2005 Oct 5;286(2):507-20. Epub 2005 Oct 5.

Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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October 2005

Comment on "Nervy links protein kinase A to plexin-mediated semaphorin repulsion".

Science 2005 Jul;309(5734):558; author reply 558

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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July 2005

Lozenge directly activates argos and klumpfuss to regulate programmed cell death.

Genes Dev 2005 May;19(9):1034-9

Center for Neurobiology and Behavior, Howard Hughes Medical Institute, Columbia University Medical School, New York, NY 10032, USA.

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May 2005

The t(8;21) translocation converts AML1 into a constitutive transcriptional repressor.

Development 2005 May 13;132(10):2263-72. Epub 2005 Apr 13.

Center for Neurobiology and Behavior, Columbia University Medical School, New York, NY 10032, USA.

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May 2005

Differing strategies for the establishment and maintenance of teashirt and homothorax repression in the Drosophila wing.

Development 2004 Nov;131(22):5683-93

Department of Biological Sciences, Columbia University, 701 West 168th Street, HHSC 1104, New York, NY 10032, USA.

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November 2004

Direct integration of Hox and segmentation gene inputs during Drosophila development.

Nature 2004 Oct;431(7009):653-9

Department of Biochemistry and Molecular Biophysics and Center for Neurobiology and Behavior, Columbia University, 701 West 168th Street, HHSC 1104, New York, New York 10032, USA.

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October 2004

A piggyBac transposon gene trap for the analysis of gene expression and function in Drosophila.

Genetics 2004 Aug;167(4):1801-11

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA.

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August 2004

Boca-dependent maturation of beta-propeller/EGF modules in low-density lipoprotein receptor proteins.

EMBO J 2004 Mar 11;23(6):1372-80. Epub 2004 Mar 11.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.

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March 2004

Two Pax are better than one.

Authors:
Richard S Mann

Nat Genet 2004 Jan;36(1):10-1

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January 2004

Target Explorer: An automated tool for the identification of new target genes for a specified set of transcription factors.

Nucleic Acids Res 2003 Jul;31(13):3589-92

Department of Biochemistry and Molecular Biophysics, Columbia University College of Physicians and Surgeons, New York, USA.

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July 2003

Requirement for two nearly identical TGIF-related homeobox genes in Drosophila spermatogenesis.

Development 2003 Jul;130(13):2853-65

Department of Biochemistry and Molecular Biophysics, Columbia University, 701 West 168th Street, HHSC 1104, New York, NY 10032, USA.

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July 2003

Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila.

Cell 2003 Feb;112(3):343-54

Department of Biochemistry and Molecular Biophysics, Center for Neurobiology and Behavior, Columbia University, 701 West 168th Street, HHSC 1104, New York, NY 10032, USA.

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February 2003

Engrailed cooperates with extradenticle and homothorax to repress target genes in Drosophila.

Development 2003 Feb;130(4):741-51

Department of Microbiology and Immunology, Kimmel Cancer Institute, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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February 2003

Specificity of Distalless repression and limb primordia development by abdominal Hox proteins.

Dev Cell 2002 Oct;3(4):487-98

Department of Biochemistry and Molecular Biophysics, Columbia University, 701 West 168th Street, HHSC 1104, New York, NY 10032, USA.

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October 2002

Combinatorial control of Drosophila eye development by eyeless, homothorax, and teashirt.

Genes Dev 2002 Sep;16(18):2415-27

Instituto de Biologia Molecular e Celular (IBMC), 4150-180 Porto, Portugal.

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September 2002

Molecular mechanisms of selector gene function and evolution.

Curr Opin Genet Dev 2002 Oct;12(5):592-600

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA.

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October 2002