Publications by authors named "Richard S Legro"

100Publications

Factors associated with study protocol adherence and bio banking participation in reproductive medicine clinical trials and their relationship to live birth.

Hum Reprod 2020 Nov 15. Epub 2020 Nov 15.

Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO, USA.

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http://dx.doi.org/10.1093/humrep/deaa232DOI Listing
November 2020

Lifestyle modifications alone or combined with hormonal contraceptives improve sexual dysfunction in women with polycystic ovary syndrome.

Fertil Steril 2020 Oct 12. Epub 2020 Oct 12.

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2020.08.1396DOI Listing
October 2020

A positive serum pregnancy test in a patient on the potent teratogen lenalidomide: a distressing result provides a valuable learning opportunity.

Int J Dermatol 2020 Sep 29. Epub 2020 Sep 29.

Department of Dermatology, Penn State Health, Hershey, PA, USA.

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http://dx.doi.org/10.1111/ijd.15197DOI Listing
September 2020

Highly elevated level of antimüllerian hormone associated with preterm delivery in polycystic ovary syndrome patients who underwent ovulation induction.

Fertil Steril 2020 Aug 31. Epub 2020 Aug 31.

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1016/j.fertnstert.2020.06.015DOI Listing
August 2020

11-Oxygenated C19 Steroids Do Not Distinguish the Hyperandrogenic Phenotype of PCOS Daughters from Girls with Obesity.

J Clin Endocrinol Metab 2020 Nov;105(11)

Division of Endocrinology, Diabetes, and Bone Diseases, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1210/clinem/dgaa532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500474PMC
November 2020

Increased Body Mass Index Is Associated With A Nondilutional Reduction in Antimüllerian Hormone.

J Clin Endocrinol Metab 2020 Oct;105(10)

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, California.

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http://dx.doi.org/10.1210/clinem/dgaa436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448935PMC
October 2020

Live birth after a freeze-only strategy versus fresh embryo transfer in three randomized trials considering progesterone concentration.

Reprod Biomed Online 2020 Sep 14;41(3):395-401. Epub 2020 May 14.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey PA 17033, USA.

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http://dx.doi.org/10.1016/j.rbmo.2020.04.021DOI Listing
September 2020

Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.

PLoS Med 2020 06 23;17(6):e1003132. Epub 2020 Jun 23.

Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1003132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310679PMC
June 2020

Large randomized controlled trials in infertility.

Fertil Steril 2020 Jun;113(6):1093-1099

Centre for Biostatistics, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.fertnstert.2020.04.037DOI Listing
June 2020

Association Between Mode of First Delivery and Subsequent Fecundity and Fertility.

JAMA Netw Open 2020 04 1;3(4):e203076. Epub 2020 Apr 1.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1001/jamanetworkopen.2020.3076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171551PMC
April 2020

Waljit S. Dhillo, MD.

Authors:
Richard S Legro

Semin Reprod Med 2019 07 23;37(4):151-152. Epub 2020 Jan 23.

Department of Obstetrics and Gynecology, Penn State College of Medicine and Penn State Health, Hershey, Pennsylvania.

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http://dx.doi.org/10.1055/s-0040-1701703DOI Listing
July 2019

The cumulative live birth rate after a freeze-only strategy versus a conventional fresh embryo transfer strategy: a call for more level 1 evidence.

BMC Med 2020 01 23;18(1):12. Epub 2020 Jan 23.

Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, 250001, China.

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http://dx.doi.org/10.1186/s12916-019-1479-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977243PMC
January 2020

Waljit S. Dhillo, MD.

Authors:
Richard S Legro

Semin Reprod Med 2019 05 23;37(3):105-106. Epub 2019 Dec 23.

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http://dx.doi.org/10.1055/s-0039-3403460DOI Listing
May 2019

Waljit S. Dhillo, MD.

Authors:
Richard S Legro

Semin Reprod Med 2019 03 17;37(2):43-44. Epub 2019 Dec 17.

Department of Obstetrics and Gynecology, Penn State College of Medicine and Penn State Health, Hershey, Pennsylvania.

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http://dx.doi.org/10.1055/s-0039-3400463DOI Listing
March 2019

Reproductive Life Planning and Contraceptive Action Planning for Privately Insured Women: The MyNewOptions Study.

Perspect Sex Reprod Health 2019 12 9;51(4):219-227. Epub 2019 Dec 9.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, PA.

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http://dx.doi.org/10.1363/psrh.12123DOI Listing
December 2019

A brief update on the evidence supporting the treatment of infertility in polycystic ovary syndrome.

Aust N Z J Obstet Gynaecol 2019 12 12;59(6):867-873. Epub 2019 Sep 12.

Monash Centre for Health Research and Implementation, Monash Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/ajo.13051DOI Listing
December 2019

Fresh versus frozen blastocyst transfer - Authors' reply.

Lancet 2019 10 11;394(10205):1228. Epub 2019 Jul 11.

Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan 250002, China. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(19)31390-XDOI Listing
October 2019

Family-based quantitative trait meta-analysis implicates rare noncoding variants in DENND1A in polycystic ovary syndrome.

J Clin Endocrinol Metab 2019 Apr 30. Epub 2019 Apr 30.

Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.

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http://dx.doi.org/10.1210/jc.2018-02496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660913PMC
April 2019

Distinctive Reproductive Phenotypes in Peripubertal Girls at Risk for Polycystic Ovary Syndrome.

J Clin Endocrinol Metab 2019 08;104(8):3355-3361

Division of Endocrinology, Diabetes, and Bone Diseases, Icahn School of Medicine at Mount Sinai, New York, New York.

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https://academic.oup.com/jcem/advance-article/doi/10.1210/jc
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http://dx.doi.org/10.1210/jc.2018-02313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589072PMC
August 2019

Frozen versus fresh single blastocyst transfer in ovulatory women: a multicentre, randomised controlled trial.

Lancet 2019 03 28;393(10178):1310-1318. Epub 2019 Feb 28.

Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, China; The Key Laboratory of Reproductive Endocrinology of Ministry of Education, Jinan, China; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, China; Center for Reproductive Medicine, Ren Ji Hospital, Shanghai, China; School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Key Laboratory of Assisted Reproduction and Reproductive Genetics, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)32843-5DOI Listing
March 2019

Functional Genetic Variation in the Anti-Müllerian Hormone Pathway in Women With Polycystic Ovary Syndrome.

J Clin Endocrinol Metab 2019 07;104(7):2855-2874

Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1210/jc.2018-02178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543512PMC
July 2019

Introduction: Stimulate the mitochondria! A Bonington approach to improving assisted reproductive technology outcomes or a call to action?

Authors:
Richard S Legro

Fertil Steril 2019 02;111(2):195-196

Penn State College of Medicine, Hershey, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2018.12.019DOI Listing
February 2019

Gerald J. Harkins, MD, MPT, FACOG.

Authors:
Richard S Legro

Semin Reprod Med 2018 03 19;36(2):95-96. Epub 2018 Dec 19.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1055/s-0038-1676367DOI Listing
March 2018

Pharmacology of medications used for ovarian stimulation.

Best Pract Res Clin Endocrinol Metab 2019 02 12;33(1):21-33. Epub 2018 Nov 12.

Department of Obstetrics and Gynecology, Penn State University College of Medicine, Hershey, PA, USA.

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http://dx.doi.org/10.1016/j.beem.2018.10.002DOI Listing
February 2019

A Vision for Improving the Assessment and Management of PCOS through International Collaboration.

Semin Reprod Med 2018 01 6;36(1):3-4. Epub 2018 Sep 6.

National Health and Medical Research Council Centre for Research Excellence in PCOS, Monash and Adelaide Universities, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1055/s-0038-1667158DOI Listing
January 2018

The International Guideline in Polycystic Ovary Syndrome.

Authors:
Richard S Legro

Semin Reprod Med 2018 01 6;36(1):1-2. Epub 2018 Sep 6.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1055/s-0038-1668119DOI Listing
January 2018

Association among depression, symptom experience, and quality of life in polycystic ovary syndrome.

Am J Obstet Gynecol 2018 09 30;219(3):279.e1-279.e7. Epub 2018 Jun 30.

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California-San Francisco, San Francisco, CA. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2018.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758922PMC
September 2018

Insulin resistance is associated with depression risk in polycystic ovary syndrome.

Fertil Steril 2018 07 13;110(1):27-34. Epub 2018 Jun 13.

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California-San Francisco, San Francisco, California.

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http://dx.doi.org/10.1016/j.fertnstert.2018.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392023PMC
July 2018

Data Do Not Support Effectiveness of Acupuncture for Improving Live Birth Rate in Women with Polycystic Ovary Syndrome.

Chin J Integr Med 2018 05 11;24(5):399-400. Epub 2018 May 11.

Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s11655-018-2842-4DOI Listing
May 2018

The Effect of Supraphysiological Estradiol on Pregnancy Outcomes Differs Between Women With PCOS and Ovulatory Women.

J Clin Endocrinol Metab 2018 07;103(7):2735-2742

Center for Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.

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http://dx.doi.org/10.1210/jc.2018-00613DOI Listing
July 2018

Obstetric complications after frozen versus fresh embryo transfer in women with polycystic ovary syndrome: results from a randomized trial.

Fertil Steril 2018 02 17;109(2):324-329. Epub 2018 Jan 17.

Center for Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, People's Republic of China; The Key Laboratory of Reproductive Endocrinology of Ministry of Education, and National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, People's Republic of China; Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China; Shanghai Key Laboratory of Assisted Reproduction and Reproductive Genetics, Shanghai, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2017.10.020DOI Listing
February 2018

Transfer of Fresh versus Frozen Embryos in Ovulatory Women.

N Engl J Med 2018 01;378(2):126-136

From the Center for Reproductive Medicine, Shandong Provincial Hospital-Shandong University, the Key Laboratory of Reproductive Endocrinology of Ministry of Education, and the National Research Center for Assisted Reproductive Technology and Reproductive Genetics (Y. Shi, D.W., Z.W., M.S. H. Liu, J.L., L.Z., Z.-J.C.), and the Center for Reproductive Medicine, Qilu Hospital of Shandong University (X.D.), Jinan, the Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, and Shanghai Key Laboratory of Assisted Reproduction and Reproductive Genetics (Y. Sun, Z.-J.C.), and the Shanghai Jiai Genetic and IVF Center, Obstetrics and Gynecology Hospital, Fudan University (X.S.), Shanghai, the Center for Reproductive Medicine of Yantai Yuhuangding Hospital, Yantai (C.H.), the Center for Reproductive Medicine, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin (Y. Zhang), the Department of Reproductive Endocrinology, Women's Hospital (Y. Zhu, D.Z.), and the Center for Reproductive Medicine (S.Z.), School of Medicine, Zhejiang University, Hangzhou, the Affiliated Hospital of Qingdao University (X.Q.) and the Center for Reproductive Medicine, Qingdao Women and Children's Hospital-Qingdao University (Y. Zhou), Qingdao, the Center for Reproduction and Genetics, Suzhou Municipal Hospital, Suzhou (H. Li), the Department of Reproductive Medicine, First Affiliated Hospital of Nanjing Medical University-Jiangsu Province Hospital, Nanjing, (X.M.), the Reproductive Medicine Center of Jinghua Hospital, Shenyang (H.R.), the Center for Reproductive Medicine, Wuhan University, Wuhan (Y.W.), the Reproductive Medicine Research Center, 6th Affiliated Hospital of Sun Yat-sen University (B.W.), the Center for Reproductive Medicine, Women and Children's Hospital of Guangdong Province (F.L.), and the Center for Reproductive Medicine, Sun Yat-sen Memorial Hospital of Sun Yat-sen University (X.C.), Guangzhou, the Center for Reproductive Medicine, Maternal and Child Health Care Hospital of Jiangxi Province, Nanchang (Q.W.), the Center for Assisted Reproduction, Northwest Women and Children's Hospital, Xi'an (H.B.), and the Center for Reproductive Medicine, Beijing Chaoyang Hospital, Beijing (Y.L.) - all in China; the Department of Biostatistics, Yale University School of Public Health, New Haven, CT (H.Z.); and the Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, PA (R.S.L.).

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http://dx.doi.org/10.1056/NEJMoa1705334DOI Listing
January 2018

Data sharing requirements: perspectives from three authors.

Fertil Steril 2018 01;109(1):44-47

IVIRMA Global, Basking Ridge, New Jersey.

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http://dx.doi.org/10.1016/j.fertnstert.2017.11.034DOI Listing
January 2018

James H. Segars, MD and Ayman Al-Hendy, MD, PhD.

Authors:
Richard S Legro

Semin Reprod Med 2017 11 3;35(6):469-470. Epub 2017 Nov 3.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1055/s-0037-1607998DOI Listing
November 2017

Iris L. Romero, MD, MS.

Authors:
Richard S Legro

Semin Reprod Med 2017 09 26;35(5):393-394. Epub 2017 Oct 26.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey Pennsylvania.

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http://dx.doi.org/10.1055/s-0037-1607361DOI Listing
September 2017

Pharmacologic Treatment of Polycystic Ovary Syndrome: Alternate and Future Paths.

Semin Reprod Med 2017 07 16;35(4):326-343. Epub 2017 Oct 16.

Department of Obstetrics and Gynecology and Public Health Sciences, Penn State University College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1055/s-0037-1603729DOI Listing
July 2017

Hot Topics Issue.

Authors:
Richard S Legro

Semin Reprod Med 2017 07 16;35(4):311-312. Epub 2017 Oct 16.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1055/s-0037-1607329DOI Listing
July 2017

Reply: "Weight and See" is not an option: birds of a feather.

Authors:
Richard S Legro

Hum Reprod 2017 10;32(10):2149

Department of Obstetrics and Gynecology, Penn State Milton S. Hershey Medical Center, Hershey, PA 17033, USA.

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http://dx.doi.org/10.1093/humrep/dex260DOI Listing
October 2017

Effect of Preconception Impaired Glucose Tolerance on Pregnancy Outcomes in Women With Polycystic Ovary Syndrome.

J Clin Endocrinol Metab 2017 10;102(10):3822-3829

Center for Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250001, China.

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http://dx.doi.org/10.1210/jc.2017-01294DOI Listing
October 2017

Response to Letter: "Normal Pubertal Development in Daughters of Women With PCOS: A Controlled Study".

J Clin Endocrinol Metab 2017 07;102(7):2561

Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania 17033.

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http://dx.doi.org/10.1210/jc.2017-00813DOI Listing
July 2017

Letter to Liu et al.'s "Efficacy of Exenatide on weight loss, metabolic parameters and pregnancy in overweight/obese polycystic ovary syndrome".

Authors:
Richard S Legro

Clin Endocrinol (Oxf) 2018 04 3;88(4):607. Epub 2017 Oct 3.

Penn State College of Medicine, Hershey, PA, USA.

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http://dx.doi.org/10.1111/cen.13474DOI Listing
April 2018

Mindfulness-Based Stress Reduction in Women with Overweight or Obesity: A Randomized Clinical Trial.

Obesity (Silver Spring) 2017 08 7;25(8):1349-1359. Epub 2017 Jul 7.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, Pennsylvania, USA.

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http://dx.doi.org/10.1002/oby.21910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529243PMC
August 2017

Age-stratified thresholds of anti-Müllerian hormone improve prediction of polycystic ovary syndrome over a population-based threshold.

Clin Endocrinol (Oxf) 2017 Dec 4;87(6):733-740. Epub 2017 Aug 4.

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco School of Medicine, San Francisco, CA, USA.

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http://dx.doi.org/10.1111/cen.13415DOI Listing
December 2017

Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome.

J Clin Endocrinol Metab 2017 08;102(8):2862-2872

Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611.

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http://dx.doi.org/10.1210/jc.2017-00612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546867PMC
August 2017

Effects of obesity treatment on female reproduction: results do not match expectations.

Authors:
Richard S Legro

Fertil Steril 2017 04;107(4):860-867

Department of Obstetrics and Gynecology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2017.02.109DOI Listing
April 2017

Treatment strategies for women with WHO group II anovulation: systematic review and network meta-analysis.

BMJ 2017 Jan 31;356:j138. Epub 2017 Jan 31.

Robinson Research Institute, Discipline of Obstetrics and Gynaecology, School of Medicine, University of Adelaide, North Adelaide, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421445PMC
http://dx.doi.org/10.1136/bmj.j138DOI Listing
January 2017

Racial and ethnic differences in the polycystic ovary syndrome metabolic phenotype.

Am J Obstet Gynecol 2017 05 16;216(5):493.e1-493.e13. Epub 2017 Jan 16.

Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO.

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http://dx.doi.org/10.1016/j.ajog.2017.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420474PMC
May 2017

Fresh versus Frozen Embryos in Polycystic Ovary Syndrome.

N Engl J Med 2016 11;375(20):e42

Penn State College of Medicine, Hershey, PA

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http://dx.doi.org/10.1056/NEJMc1611871DOI Listing
November 2016

Ovulation induction in polycystic ovary syndrome: Current options.

Authors:
Richard S Legro

Best Pract Res Clin Obstet Gynaecol 2016 Nov 21;37:152-159. Epub 2016 Sep 21.

Department of Obstetrics and Gynecology and Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bpobgyn.2016.08.001DOI Listing
November 2016

Clarisa R. Gracia, MD, MSCE.

Authors:
Richard S Legro

Semin Reprod Med 2016 11 3;34(6):313-314. Epub 2016 Nov 3.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1055/s-0036-1593977DOI Listing
November 2016

Mr. Fertility Authority, Tear Down That Weight Wall!

Authors:
Richard S Legro

Hum Reprod 2016 12 19;31(12):2662-2664. Epub 2016 Oct 19.

Departments of Obstetrics and Gynecology and Public Health Sciences, Penn State College of Medicine, M.S. Hershey Medical Center , 500 University Drive, H103, Hershey, PA 17033, USA

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http://dx.doi.org/10.1093/humrep/dew253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193329PMC
December 2016

CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 28-2016: A 31-Year-Old Woman with Infertility.

N Engl J Med 2016 Sep;375(11):1069-77

From the Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey (R.S.L.); and the Departments of Infectious Disease (R.M.H.), Radiology (A.K.), and Pathology (D.J.R.), Massachusetts General Hospital, and the Departments of Infectious Disease (R.M.H.), Radiology (A.K.), and Pathology (D.J.R.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1609110DOI Listing
September 2016

Lessons from Genome Wide Association Studies.

Authors:
Richard S Legro

Semin Reprod Med 2016 07 11;34(4):191-2. Epub 2016 Aug 11.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1055/s-0036-1586216DOI Listing
July 2016

The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance.

Hum Reprod Update 2016 11 10;22(6):687-708. Epub 2016 Aug 10.

Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Monash Medical Centre, 43-51 Kanooka Grove, Clayton, VIC 3168, Australia.

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http://dx.doi.org/10.1093/humupd/dmw025DOI Listing
November 2016

Polycystic ovary syndrome.

Nat Rev Dis Primers 2016 08 11;2:16057. Epub 2016 Aug 11.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Hacettepe University School of Medicine, Hacettepe, Ankara, Turkey.

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http://dx.doi.org/10.1038/nrdp.2016.57DOI Listing
August 2016

Fresh versus Frozen Embryos for Infertility in the Polycystic Ovary Syndrome.

N Engl J Med 2016 Aug;375(6):523-33

From the Center for Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Key Laboratory of Reproductive Endocrinology, Shandong University, Ministry of Education, and National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan (Z.-J.C., Y. Shi, D.W., J. Li, J. Yan, Y.Q., H. Zhao), Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University (Z.-J.C., Y. Sun), and Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics (Z.-J.C., Y. Sun), Shanghai, Center for Reproductive Medicine, Maternal and Child Health Hospital in Guangxi, Guangxi (B.Z.), Reproductive Medicine Center, the Sixth Affiliated Hospital of Sun Yat-sen University (X.L.) and Center for Reproductive Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University (D.Y.), Guangzhou, Center for Reproductive Medicine, the First Affiliated Hospital of Anhui Medical University, Hefei (Y.C.), Center for Reproductive Medicine, Wuhan University, Wuhan (J. Yang), Department of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Nanjing (J. Liu), Reproductive Medicine Center of Jinghua Hospital, Shenyang (N.W.), Center for Reproductive Medicine, Jiangxi Provincial Maternal and Child Health Hospital, Nanchang (L.T.), Center for Reproductive Medicine of Yantai Yuhuangding Hospital, Yantai (C.H.), Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital Affiliated to Zhejiang University School of Medicine, Hangzhou (F.Z.), Assisted Reproduction Center, Maternal and Child Health Care Hospital of Shanxi Province, Xi'an (J.S.), and Center for Reproduction and Genetics, Suzhou Municipal Hospital, Suzhou (Y.X.) - all in China; Department of Biostatistics, Yale University School of Public Health, New Haven, CT (H. Zhang); and Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey (R.S.L.).

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http://dx.doi.org/10.1056/NEJMoa1513873DOI Listing
August 2016

Introduction: Evidence-based in vitro fertilization treatment of fresh versus frozen embryo transfer: peeling away the layers of the onion.

Authors:
Richard S Legro

Fertil Steril 2016 Aug 13;106(2):239-40. Epub 2016 Jul 13.

Department of Obstetrics and Gynecology and Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2016.06.031DOI Listing
August 2016

Weight Loss and Lowering Androgens Predict Improvements in Health-Related Quality of Life in Women With PCOS.

J Clin Endocrinol Metab 2016 08 2;101(8):2966-74. Epub 2016 Jun 2.

Departments of Obstetrics and Gynecology (A.D., L.M., C.C.) and Psychiatry (D.B.S., K.C.A.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104; Departments of Obstetrics and Gynecology (C.L.G., S.J.E., R.S.L.), and Public Health Sciences (A.R.K., C.M.S., R.S.L.), Penn State College of Medicine, Hershey, Pennsylvania 17033; and Departments of Nutritional Sciences (P.M.K.-E., J.F.) and Kinesiology (N.I.W.), Penn State College of Health and Human Development, University Park, Pennsylvania 16802.

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http://dx.doi.org/10.1210/jc.2016-1896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971336PMC
August 2016

Baseline AMH Level Associated With Ovulation Following Ovulation Induction in Women With Polycystic Ovary Syndrome.

J Clin Endocrinol Metab 2016 09 26;101(9):3288-96. Epub 2016 May 26.

Epidemiology Branch, Division of Intramural Population Health Research (S.L.M.), Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, Maryland; Department of Obstetrics and Gynecology (R.S.L.), Pennsylvania State University, Hershey, Pennsylvania; Department of Obstetrics and Gynecology (M.P.D.), Augusta University, Augusta, Georgia; Department of Obstetrics and Gynecology (C.C.), University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Department of Obstetrics and Gynecology (A.Z.S.), University of North Carolina, Chapel Hill, North Carolina; Department of Obstetrics and Gynecology (R.A., N.S.), University of Colorado Anschutz Medical Campus, Aurora, Colorado; Department of Obstetrics and Gynecology (G.M.C.), University of Michigan, Ann Arbor, Michigan; Department of Obstetrics and Gynecology (P.R.C.), University of Vermont, Burlington, Vermont; Department of Biostatistics (H.H., H.Z.), Yale University School of Public Health, New Haven, Connecticut; Fertility and Infertility Branch (E.E.), Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, Maryland; and Department of Obstetrics, Gynecology and Reproductive Sciences (M.I.C.), University of California-San Francisco, San Francisco, California.

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http://dx.doi.org/10.1210/jc.2016-1340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010565PMC
September 2016

Exclusion of Women of Childbearing Potential in Clinical Trials of Type 2 Diabetes Medications: A Review of Protocol-Based Barriers to Enrollment.

Diabetes Care 2016 Jun 18;39(6):1004-9. Epub 2016 Apr 18.

Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, PA Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA

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http://dx.doi.org/10.2337/dc15-2723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878221PMC
June 2016

Vitamin D Status Relates to Reproductive Outcome in Women With Polycystic Ovary Syndrome: Secondary Analysis of a Multicenter Randomized Controlled Trial.

J Clin Endocrinol Metab 2016 08 17;101(8):3027-35. Epub 2016 May 17.

Department of Obstetrics, Gynecology, and Reproductive Sciences (L.P., H.Z., J.W.), Yale School of Medicine, New Haven, Connecticut 06510; Department of Obstetrics and Gynecology (N.F.S., W.D.S.), University of Colorado, Denver, Colorado 80238; Department of Obstetrics and Gynecology (M.P.D.), Georgia Regents University, Augusta, Georgia 30912; Department of Obstetrics and Gynecology (C.C.), University of Pennsylvania, Philadelphia, Pennsylvania 19104; Baylor College of Medicine (S.A.C.), Houston, Texas 77030; University of Alabama (M.P.S.), Birmingham, Alabama 35233; University of Texas Southwestern Medical Center (B.R.C.), Dallas, Texas 75390; University of Medicine and Dentistry of New Jersey (P.G.M.), Newark, New Jersey 07103; Stanford University (N.A.C.), Stanford, California 94305; University of Pittsburgh (G.G.G.), Pittsburgh, Pennsylvania 15206; Department of Medicine (J.E.N.), Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298; Department of Obstetrics and Gynecology and Duke Clinical Research Institute (E.M.), Duke University Medical Center, Durham North Carolina 27710; and Department of Obstetrics and Gynecology (R.S.L.), Penn State College of Medicine, Hershey, Pennsylvania 17033.

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http://dx.doi.org/10.1210/jc.2015-4352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971341PMC
August 2016

Benefit of Delayed Fertility Therapy With Preconception Weight Loss Over Immediate Therapy in Obese Women With PCOS.

J Clin Endocrinol Metab 2016 07 12;101(7):2658-66. Epub 2016 May 12.

Department of Obstetrics and Gynecology (R.S.L., W.C.D., C.L.G., S.J.E.), Penn State College of Medicine, Hershey, Pennsylvania; Department of Public Health Sciences (R.S.L., A.R.K., C.M.S.), Penn State College of Medicine, Hershey, Pennsylvania; Department of Nutritional Sciences (P.M.K.-E.), Penn State College of Health and Human Development, University Park, Pennsylvania; Department of Kinesiology (N.W.), Penn State College of Health and Human Development, University Park, Pennsylvania; Departments of Psychiatry (K.C.A., D.B.S.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Surgery (D.B.S.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Obstetrics and Gynecology (M.P.D.), Wayne State University, Detroit, Michigan; Department of Obstetrics and Gynecology (W.D.S.), University of Colorado, Denver, Colorado; Department of Obstetrics and Gynecology (P.R.C.), University of Vermont, Burlington, Vermont; Department of Obstetrics and Gynecology (G.M.C.), University of Michigan, Ann Arbor, Michigan; Department of Obstetrics and Gynecology (K.T.B., C.C., A.D.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Obstetrics and Gynecology (W.B.), University of Alabama Birmingham, Birmingham, Alabama; Carolinas Medical Center (R.U.), Charlotte, North Carolina; Department of Obstetrics and Gynecology (S.L.), Virginia Commonwealth University, Richmond, Virginia; Department of Obstetrics and Gynecology (V.B.), Stanford University Medical Center, Stanford, California; Department of Biostatistics (H.H.), Yale University School of Public Health, New Haven, Connecticut; Fertility and Infertility Branch (E.E.), Eunice Kennedy Shriver NICHD, Rockville, Maryland.

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http://dx.doi.org/10.1210/jc.2016-1659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929837PMC
July 2016

Combined hormonal contraception use in reproductive-age women with contraindications to estrogen use.

Am J Obstet Gynecol 2016 09 5;215(3):330.e1-7. Epub 2016 Apr 5.

Division of General Internal Medicine, Department of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA.

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http://dx.doi.org/10.1016/j.ajog.2016.03.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861494PMC
September 2016

Increased antimüllerian hormone levels and other reproductive endocrine changes in adult male relatives of women with polycystic ovary syndrome.

Fertil Steril 2016 07 1;106(1):50-55. Epub 2016 Apr 1.

Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2016.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930891PMC
July 2016