Richard S Houlston

Richard S Houlston

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Richard S Houlston

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Impact of mitochondrial DNA mutations in multiple myeloma.

Blood Cancer J 2020 May 1;10(5):46. Epub 2020 May 1.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1038/s41408-020-0315-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195394PMC
May 2020

Reference bias in the Illumina Isaac aligner.

Bioinformatics 2020 May 21. Epub 2020 May 21.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1093/bioinformatics/btaa514DOI Listing
May 2020

Leveraging Genome and Phenome-Wide Association Studies to Investigate Genetic Risk of Acute Lymphoblastic Leukemia.

Cancer Epidemiol Biomarkers Prev 2020 May 28. Epub 2020 May 28.

Children's Health and Discovery Initiative, Department of Pediatrics, Duke University, Durham, North Carolina.

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http://dx.doi.org/10.1158/1055-9965.EPI-20-0113DOI Listing
May 2020

Genetic predisposition for multiple myeloma.

Leukemia 2020 Mar 8;34(3):697-708. Epub 2020 Jan 8.

Hematology and Transfusion Medicine, Department of Laboratory Medicine, BMC B13, 221 84, Lund, Sweden.

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http://dx.doi.org/10.1038/s41375-019-0703-6DOI Listing
March 2020

Comprehensive analysis of colorectal cancer-risk loci and survival outcome: A prognostic role for CDH1 variants.

Eur J Cancer 2020 01 14;124:56-63. Epub 2019 Nov 14.

Division of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.09.024DOI Listing
January 2020

Mendelian randomisation: A powerful and inexpensive method for identifying and excluding non-genetic risk factors for colorectal cancer.

Mol Aspects Med 2019 10 4;69:41-47. Epub 2019 Feb 4.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1016/j.mam.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856712PMC
October 2019

Analysis of 153 115 patients with hematological malignancies refines the spectrum of familial risk.

Blood 2019 09 8;134(12):960-969. Epub 2019 Aug 8.

Division of Molecular Genetic Epidemiology, German Cancer Research Centre, Heidelberg, Germany.

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http://dx.doi.org/10.1182/blood.2019001362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789511PMC
September 2019

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 515.33 TERT-CLPTM1Ll Region.

J Thorac Oncol 2019 08 19;14(8):1360-1369. Epub 2019 Apr 19.

Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864193028
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http://dx.doi.org/10.1016/j.jtho.2019.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833942PMC
August 2019

Mutational processes contributing to the development of multiple myeloma.

Blood Cancer J 2019 08 6;9(8):60. Epub 2019 Aug 6.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1038/s41408-019-0221-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684612PMC
August 2019

Regions of homozygosity as risk factors for multiple myeloma.

Ann Hum Genet 2019 07 15;83(4):231-238. Epub 2019 Feb 15.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1111/ahg.12304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563058PMC
July 2019

Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis.

Cancer Epidemiol Biomarkers Prev 2019 05 30;28(5):935-942. Epub 2019 Jan 30.

Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075698PMC
May 2019

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

Nat Commun 2019 05 14;10(1):2154. Epub 2019 May 14.

Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://www.nature.com/articles/s41467-019-09775-w
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http://dx.doi.org/10.1038/s41467-019-09775-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517433PMC
May 2019

Types of second primary cancers influence survival in chronic lymphocytic and hairy cell leukemia patients.

Blood Cancer J 2019 03 26;9(4):40. Epub 2019 Mar 26.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, D-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41408-019-0201-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435725PMC
March 2019

Genetic predisposition to B-cell acute lymphoblastic leukemia at 14q11.2 is mediated by a CEBPE promoter polymorphism.

Leukemia 2019 01 6;33(1):1-14. Epub 2018 Jul 6.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SM2 5NG, United Kingdom.

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http://dx.doi.org/10.1038/s41375-018-0184-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327050PMC
January 2019

Publisher Correction: Cancer genetics, precision prevention and a call to action.

Nat Genet 2019 01;51(1):196

Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.

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http://www.nature.com/articles/s41588-018-0326-2
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http://dx.doi.org/10.1038/s41588-018-0326-2DOI Listing
January 2019

The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study.

Authors:
Mattias Johansson Robert Carreras-Torres Ghislaine Scelo Mark P Purdue Daniela Mariosa David C Muller Nicolas J Timpson Philip C Haycock Kevin M Brown Zhaoming Wang Yuanqing Ye Jonathan N Hofmann Matthieu Foll Valerie Gaborieau Mitchell J Machiela Leandro M Colli Peng Li Jean-Guillaume Garnier Helene Blanche Anne Boland Laurie Burdette Egor Prokhortchouk Konstantin G Skryabin Meredith Yeager Sanja Radojevic-Skodric Simona Ognjanovic Lenka Foretova Ivana Holcatova Vladimir Janout Dana Mates Anush Mukeriya Stefan Rascu David Zaridze Vladimir Bencko Cezary Cybulski Eleonora Fabianova Viorel Jinga Jolanta Lissowska Jan Lubinski Marie Navratilova Peter Rudnai Simone Benhamou Geraldine Cancel-Tassin Olivier Cussenot Elisabete Weiderpass Börje Ljungberg Raviprakash Tumkur Sitaram Christel Häggström Fiona Bruinsma Susan J Jordan Gianluca Severi Ingrid Winship Kristian Hveem Lars J Vatten Tony Fletcher Susanna C Larsson Alicja Wolk Rosamonde E Banks Peter J Selby Douglas F Easton Gabriella Andreotti Laura E Beane Freeman Stella Koutros Satu Männistö Stephanie Weinstein Peter E Clark Todd L Edwards Loren Lipworth Susan M Gapstur Victoria L Stevens Hallie Carol Matthew L Freedman Mark M Pomerantz Eunyoung Cho Kathryn M Wilson J Michael Gaziano Howard D Sesso Neal D Freedman Alexander S Parker Jeanette E Eckel-Passow Wen-Yi Huang Richard J Kahnoski Brian R Lane Sabrina L Noyes David Petillo Bin Tean Teh Ulrike Peters Emily White Garnet L Anderson Lisa Johnson Juhua Luo Julie Buring I-Min Lee Wong-Ho Chow Lee E Moore Timothy Eisen Marc Henrion James Larkin Poulami Barman Bradley C Leibovich Toni K Choueiri G Mark Lathrop Jean-Francois Deleuze Marc Gunter James D McKay Xifeng Wu Richard S Houlston Stephen J Chanock Caroline Relton J Brent Richards Richard M Martin George Davey Smith Paul Brennan

PLoS Med 2019 01 3;16(1):e1002724. Epub 2019 Jan 3.

International Agency for Research on Cancer (IARC), Lyon, France.

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http://dx.doi.org/10.1371/journal.pmed.1002724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317776PMC
January 2019

Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2019 01 10;10(1):213. Epub 2019 Jan 10.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-08107-8
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http://dx.doi.org/10.1038/s41467-018-08107-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328616PMC
January 2019

Leveraging Human Genetics to Guide Cancer Drug Development.

JCO Clin Cancer Inform 2018 12;2:1-11

All authors: The Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1200/CCI.18.00077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874034PMC
December 2018

Multiple mechanisms can disrupt oncogenic pathways in multiple myeloma.

Oncotarget 2018 Nov 9;9(88):35801-35802. Epub 2018 Nov 9.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.18632/oncotarget.26301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254677PMC
November 2018

Corrigendum re "Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma" [Eur Urol 2017;72:747-54].

Authors:
Mitchell J Machiela Jonathan N Hofmann Robert Carreras-Torres Kevin M Brown Mattias Johansson Zhaoming Wang Matthieu Foll Peng Li Nathaniel Rothman Sharon A Savage Valerie Gaborieau James D McKay Yuanqing Ye Marc Henrion Fiona Bruinsma Susan Jordan Gianluca Severi Kristian Hveem Lars J Vatten Tony Fletcher Kvetoslava Koppova Susanna C Larsson Alicja Wolk Rosamonde E Banks Peter J Selby Douglas F Easton Paul Pharoah Gabriella Andreotti Laura E Beane Freeman Stella Koutros Demetrius Albanes Satu Mannisto Stephanie Weinstein Peter E Clark Todd E Edwards Loren Lipworth Susan M Gapstur Victoria L Stevens Hallie Carol Matthew L Freedman Mark M Pomerantz Eunyoung Cho Peter Kraft Mark A Preston Kathryn M Wilson J Michael Gaziano Howard S Sesso Amanda Black Neal D Freedman Wen-Yi Huang John G Anema Richard J Kahnoski Brian R Lane Sabrina L Noyes David Petillo Leandro M Colli Joshua N Sampson Celine Besse Helene Blanche Anne Boland Laurie Burdette Egor Prokhortchouk Konstantin G Skryabin Meredith Yeager Mirjana Mijuskovic Miodrag Ognjanovic Lenka Foretova Ivana Holcatova Vladimir Janout Dana Mates Anush Mukeriya Stefan Rascu David Zaridze Vladimir Bencko Cezary Cybulski Eleonora Fabianova Viorel Jinga Jolanta Lissowska Jan Lubinski Marie Navratilova Peter Rudnai Neonila Szeszenia-Dabrowska Simone Benhamou Geraldine Cancel-Tassin Olivier Cussenot H B As Bueno-de-Mesquita Federico Canzian Eric J Duell Börje Ljungberg Raviprakash T Sitaram Ulrike Peters Emily White Garnet L Anderson Lisa Johnson Juhua Luo Julie Buring I-Min Lee Wong-Ho Chow Lee E Moore Christopher Wood Timothy Eisen James Larkin Toni K Choueiri G Mark Lathrop Bin Tean Teh Jean-Francois Deleuze Xifeng Wu Richard S Houlston Paul Brennan Stephen J Chanock Ghislaine Scelo Mark P Purdue

Eur Urol 2018 09 28;74(3):e85-e86. Epub 2018 May 28.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, MS, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03022838183036
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http://dx.doi.org/10.1016/j.eururo.2018.05.017DOI Listing
September 2018

Large-scale Analysis Demonstrates Familial Testicular Cancer to have Polygenic Aetiology.

Eur Urol 2018 09 21;74(3):248-252. Epub 2018 Jun 21.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; William Harvey Research Institute, Queen Mary University, London, UK; Department of Clinical Genetics, Guys and St Thomas NHS Foundation Trust, London, UK; Public Health England, National Cancer Registration and Analysis Service, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2018.05.036DOI Listing
September 2018

Cancer genetics, precision prevention and a call to action.

Nat Genet 2018 09 29;50(9):1212-1218. Epub 2018 Aug 29.

Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.

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http://www.nature.com/articles/s41588-018-0202-0
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http://dx.doi.org/10.1038/s41588-018-0202-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420140PMC
September 2018

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2018 09 13;9(1):3707. Epub 2018 Sep 13.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-04989-w
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http://dx.doi.org/10.1038/s41467-018-04989-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137048PMC
September 2018

Familial risks of acute myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms.

Blood 2018 08 10;132(9):973-976. Epub 2018 Jul 10.

Division of Molecular Genetic Epidemiology, German Cancer Research Centre, Heidelberg, Germany.

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http://dx.doi.org/10.1182/blood-2018-06-858597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194341PMC
August 2018

Capture Hi-C Library Generation and Analysis to Detect Chromatin Interactions.

Curr Protoc Hum Genet 2018 Jul 6:e63. Epub 2018 Jul 6.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1002/cphg.63DOI Listing
July 2018

Large-scale Sequencing of Testicular Germ Cell Tumour (TGCT) Cases Excludes Major TGCT Predisposition Gene.

Eur Urol 2018 06 9;73(6):828-831. Epub 2018 Feb 9.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; William Harvey Research Institute, Queen Mary University, London, UK; Department of Clinical Genetics, Guys and St Thomas NHS Foundation Trust, London, UK; National Cancer Registration and Analysis Service, Public Health England, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2018.01.021DOI Listing
June 2018

Genome-Wide Association Studies in Glioma.

Cancer Epidemiol Biomarkers Prev 2018 04 30;27(4):418-428. Epub 2018 Jan 30.

Department of Medicine, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-1080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931394PMC
April 2018

IKZF1 Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.

J Clin Oncol 2018 04 2;36(12):1240-1249. Epub 2018 Mar 2.

Martin Stanulla, Elif Dagdan, Stefanie V. Junk, Laura Hinze, Norman Klein, Christian P. Kratz, Petra Dörge, Doris Steinemann, and Martin Zimmermann, Hannover Medical School; Petra Dörge, German Center for Infection Research, Hannover; Anja Möricke, Kirsten Bleckmann, Denis Schewe, Gunnar Cario, and Martin Schrappe, University Hospital Schleswig-Holstein; Britt-Sabina Petersen and Andre Franke, Kiel University, Kiel; Cornelia Eckert and Stefanie Groeneveld-Krentz, Charité University Hospital; Wolf-Dieter Ludwig, HELIOS-Clinic Berlin-Buch, Berlin; Rolf Koehler, Claus R. Bartram, Andreas Kulozik, and Martina U. Muckenthaler, University of Heidelberg, Heidelberg; Arndt Borkhardt, Heinrich-Heine University, Düsseldorf, Germany; Marketa Zaliova, Charles University and University Hospital Motol, Prague, Czech Republic; Chiara Palmi, Giovanni Cazzaniga, and Andrea Biondi, Azienda Ospedaliera San Gerardo; Maria Grazia Valsecchi, University of Milano-Bicocca, Monza; Geertruy te Kronnie and Giuseppe Basso, University of Padova, Padua, Italy; Jean-Pierre Bourquin and Beat Bornhauser, University Children's Hospital Zurich, Zurich, Switzerland; Shai Izraeli, Sheba Medical Center Tel-Hashomer and Tel Aviv University, Tel Aviv, Israel; Oskar A. Haas and Renate Panzer-Grümayer, St Anna Kinderkrebsforschung and Medical University Vienna, Vienna, Austria; Hélène Cavé, Robert Debré Hospital and Paris-Diderot University, Paris, France; and Richard S. Houlston, The Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2017.74.3617DOI Listing
April 2018

Combined linkage and association analysis of classical Hodgkin lymphoma.

Oncotarget 2018 Apr 17;9(29):20377-20385. Epub 2018 Apr 17.

School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom.

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http://dx.doi.org/10.18632/oncotarget.24872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945548PMC
April 2018

Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma.

Authors:
Mitchell J Machiela Jonathan N Hofmann Robert Carreras-Torres Kevin M Brown Mattias Johansson Zhaoming Wang Matthieu Foll Peng Li Nathaniel Rothman Sharon A Savage Valerie Gaborieau James D McKay Yuanqing Ye Marc Henrion Fiona Bruinsma Susan Jordan Gianluca Severi Kristian Hveem Lars J Vatten Tony Fletcher Kvetoslava Koppova Susanna C Larsson Alicja Wolk Rosamonde E Banks Peter J Selby Douglas F Easton Paul Pharoah Gabriella Andreotti Laura E Beane Freeman Stella Koutros Demetrius Albanes Satu Mannisto Stephanie Weinstein Peter E Clark Todd E Edwards Loren Lipworth Susan M Gapstur Victoria L Stevens Hallie Carol Matthew L Freedman Mark M Pomerantz Eunyoung Cho Peter Kraft Mark A Preston Kathryn M Wilson J Michael Gaziano Howard S Sesso Amanda Black Neal D Freedman Wen-Yi Huang John G Anema Richard J Kahnoski Brian R Lane Sabrina L Noyes David Petillo Leandro M Colli Joshua N Sampson Celine Besse Helene Blanche Anne Boland Laurie Burdette Egor Prokhortchouk Konstantin G Skryabin Meredith Yeager Mirjana Mijuskovic Miodrag Ognjanovic Lenka Foretova Ivana Holcatova Vladimir Janout Dana Mates Anush Mukeriya Stefan Rascu David Zaridze Vladimir Bencko Cezary Cybulski Eleonora Fabianova Viorel Jinga Jolanta Lissowska Jan Lubinski Marie Navratilova Peter Rudnai Neonila Szeszenia-Dabrowska Simone Benhamou Geraldine Cancel-Tassin Olivier Cussenot H Bas Bueno-de-Mesquita Federico Canzian Eric J Duell Börje Ljungberg Raviprakash T Sitaram Ulrike Peters Emily White Garnet L Anderson Lisa Johnson Juhua Luo Julie Buring I-Min Lee Wong-Ho Chow Lee E Moore Christopher Wood Timothy Eisen James Larkin Toni K Choueiri G Mark Lathrop Bin Tean Teh Jean-Francois Deleuze Xifeng Wu Richard S Houlston Paul Brennan Stephen J Chanock Ghislaine Scelo Mark P Purdue

Eur Urol 2017 11 7;72(5):747-754. Epub 2017 Aug 7.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, MS, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03022838173063
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http://dx.doi.org/10.1016/j.eururo.2017.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641242PMC
November 2017

Genome-wide association studies of cancer: current insights and future perspectives.

Nat Rev Cancer 2017 11 13;17(11):692-704. Epub 2017 Oct 13.

Division of Genetics and Epidemiology, The Institute of Cancer Research.

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http://dx.doi.org/10.1038/nrc.2017.82DOI Listing
November 2017

Constitutional mutation in CDKN2A is associated with long term survivorship in multiple myeloma: a case report.

BMC Cancer 2017 Nov 6;17(1):718. Epub 2017 Nov 6.

Division of Molecular Pathology, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1186/s12885-017-3715-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674776PMC
November 2017

Second cancer risk following Hodgkin lymphoma.

Oncotarget 2017 Oct 14;8(45):78261-78262. Epub 2017 Sep 14.

Amit Sud: Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.18632/oncotarget.20876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667959PMC
October 2017

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

Authors:
James D McKay Rayjean J Hung Younghun Han Xuchen Zong Robert Carreras-Torres David C Christiani Neil E Caporaso Mattias Johansson Xiangjun Xiao Yafang Li Jinyoung Byun Alison Dunning Karen A Pooley David C Qian Xuemei Ji Geoffrey Liu Maria N Timofeeva Stig E Bojesen Xifeng Wu Loic Le Marchand Demetrios Albanes Heike Bickeböller Melinda C Aldrich William S Bush Adonina Tardon Gad Rennert M Dawn Teare John K Field Lambertus A Kiemeney Philip Lazarus Aage Haugen Stephen Lam Matthew B Schabath Angeline S Andrew Hongbing Shen Yun-Chul Hong Jian-Min Yuan Pier Alberto Bertazzi Angela C Pesatori Yuanqing Ye Nancy Diao Li Su Ruyang Zhang Yonathan Brhane Natasha Leighl Jakob S Johansen Anders Mellemgaard Walid Saliba Christopher A Haiman Lynne R Wilkens Ana Fernandez-Somoano Guillermo Fernandez-Tardon Henricus F M van der Heijden Jin Hee Kim Juncheng Dai Zhibin Hu Michael P A Davies Michael W Marcus Hans Brunnström Jonas Manjer Olle Melander David C Muller Kim Overvad Antonia Trichopoulou Rosario Tumino Jennifer A Doherty Matt P Barnett Chu Chen Gary E Goodman Angela Cox Fiona Taylor Penella Woll Irene Brüske H-Erich Wichmann Judith Manz Thomas R Muley Angela Risch Albert Rosenberger Kjell Grankvist Mikael Johansson Frances A Shepherd Ming-Sound Tsao Susanne M Arnold Eric B Haura Ciprian Bolca Ivana Holcatova Vladimir Janout Milica Kontic Jolanta Lissowska Anush Mukeria Simona Ognjanovic Tadeusz M Orlowski Ghislaine Scelo Beata Swiatkowska David Zaridze Per Bakke Vidar Skaug Shanbeh Zienolddiny Eric J Duell Lesley M Butler Woon-Puay Koh Yu-Tang Gao Richard S Houlston John McLaughlin Victoria L Stevens Philippe Joubert Maxime Lamontagne David C Nickle Ma'en Obeidat Wim Timens Bin Zhu Lei Song Linda Kachuri María Soler Artigas Martin D Tobin Louise V Wain Thorunn Rafnar Thorgeir E Thorgeirsson Gunnar W Reginsson Kari Stefansson Dana B Hancock Laura J Bierut Margaret R Spitz Nathan C Gaddis Sharon M Lutz Fangyi Gu Eric O Johnson Ahsan Kamal Claudio Pikielny Dakai Zhu Sara Lindströem Xia Jiang Rachel F Tyndale Georgia Chenevix-Trench Jonathan Beesley Yohan Bossé Stephen Chanock Paul Brennan Maria Teresa Landi Christopher I Amos

Nat Genet 2017 Jul 12;49(7):1126-1132. Epub 2017 Jun 12.

Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

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http://dx.doi.org/10.1038/ng.3892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510465PMC
July 2017

Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

Authors:
Ghislaine Scelo Mark P Purdue Kevin M Brown Mattias Johansson Zhaoming Wang Jeanette E Eckel-Passow Yuanqing Ye Jonathan N Hofmann Jiyeon Choi Matthieu Foll Valerie Gaborieau Mitchell J Machiela Leandro M Colli Peng Li Joshua N Sampson Behnoush Abedi-Ardekani Celine Besse Helene Blanche Anne Boland Laurie Burdette Amelie Chabrier Geoffroy Durand Florence Le Calvez-Kelm Egor Prokhortchouk Nivonirina Robinot Konstantin G Skryabin Magdalena B Wozniak Meredith Yeager Gordana Basta-Jovanovic Zoran Dzamic Lenka Foretova Ivana Holcatova Vladimir Janout Dana Mates Anush Mukeriya Stefan Rascu David Zaridze Vladimir Bencko Cezary Cybulski Eleonora Fabianova Viorel Jinga Jolanta Lissowska Jan Lubinski Marie Navratilova Peter Rudnai Neonila Szeszenia-Dabrowska Simone Benhamou Geraldine Cancel-Tassin Olivier Cussenot Laura Baglietto Heiner Boeing Kay-Tee Khaw Elisabete Weiderpass Borje Ljungberg Raviprakash T Sitaram Fiona Bruinsma Susan J Jordan Gianluca Severi Ingrid Winship Kristian Hveem Lars J Vatten Tony Fletcher Kvetoslava Koppova Susanna C Larsson Alicja Wolk Rosamonde E Banks Peter J Selby Douglas F Easton Paul Pharoah Gabriella Andreotti Laura E Beane Freeman Stella Koutros Demetrius Albanes Satu Männistö Stephanie Weinstein Peter E Clark Todd L Edwards Loren Lipworth Susan M Gapstur Victoria L Stevens Hallie Carol Matthew L Freedman Mark M Pomerantz Eunyoung Cho Peter Kraft Mark A Preston Kathryn M Wilson J Michael Gaziano Howard D Sesso Amanda Black Neal D Freedman Wen-Yi Huang John G Anema Richard J Kahnoski Brian R Lane Sabrina L Noyes David Petillo Bin Tean Teh Ulrike Peters Emily White Garnet L Anderson Lisa Johnson Juhua Luo Julie Buring I-Min Lee Wong-Ho Chow Lee E Moore Christopher Wood Timothy Eisen Marc Henrion James Larkin Poulami Barman Bradley C Leibovich Toni K Choueiri G Mark Lathrop Nathaniel Rothman Jean-Francois Deleuze James D McKay Alexander S Parker Xifeng Wu Richard S Houlston Paul Brennan Stephen J Chanock

Nat Commun 2017 06 9;8:15724. Epub 2017 Jun 9.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ncomms15724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472706PMC
June 2017

Risk of Second Cancer in Hodgkin Lymphoma Survivors and Influence of Family History.

J Clin Oncol 2017 May 13;35(14):1584-1590. Epub 2017 Mar 13.

Amit Sud and Richard S. Houlston, The Institute of Cancer Research, London, United Kingdom; Hauke Thomsen and Kari Hemminki, German Cancer Research Centre, Heidelberg, Germany; and Kristina Sundquist and Kari Hemminki, Centre for Primary Health Care Research, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1200/JCO.2016.70.9709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455705PMC
May 2017

Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21.2.

Nat Commun 2017 03 3;8:14616. Epub 2017 Mar 3.

Division of Genetics and Epidemiology, The Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK.

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http://dx.doi.org/10.1038/ncomms14616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337971PMC
March 2017

Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.

Nat Genet 2017 03;49(4):651

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http://dx.doi.org/10.1038/ng0417-651aDOI Listing
March 2017

Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.

Gastroenterology 2017 01 3;152(1):75-77.e4. Epub 2016 Oct 3.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; Division of Pathology, The Institute of Cancer Research, London, UK. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.09.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860724PMC
January 2017

CanVar: A resource for sharing germline variation in cancer patients.

F1000Res 2016 5;5:2813. Epub 2016 Dec 5.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.12688/f1000research.10058.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200944PMC
December 2016