Publications by authors named "Richard R Furman"

131 Publications

Outcomes in CLL patients with NOTCH1 regulatory pathway mutations.

Authors:
Daniel R Helbig Ghaith Abu-Zeinah Erica Bhavsar Paul J Christos Richard R Furman John N Allan

Am J Hematol 2021 Feb 24. Epub 2021 Feb 24.

Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY.

View Article and Find Full Text PDF
February 2021

ROR1 targeting with the antibody drug-conjugate VLS-101 is effective in Richter syndrome patient-derived xenograft mouse models.

Authors:
Tiziana Vaisitti Francesca Arruga Nicoletta Vitale Thanh-Trang Thi Lee Mira Ko Amy Chadburn Esteban Braggio Arianna Di Napoli Andrea Iannello John Allan Langdon L Miller Brian J Lannutti Richard R Furman Katti Jessen Silvia Deaglio

Blood 2021 Jan 14. Epub 2021 Jan 14.

University of Torino, Turin, Indiana, Italy.

View Article and Find Full Text PDF
January 2021

Impact of idelalisib on health-related quality of life in patients with relapsed chronic lymphocytic leukemia in a phase III randomized trial.

Authors:
Paolo Ghia Steven E Coutre Bruce D Cheson Jacqueline C Barrientos Peter Hillmen Andrew R Pettitt Andrew D Zelenetz Sanatan Shreay Michael Hallek Richard R Furman

Haematologica 2020 10 1;105(10):e519. Epub 2020 Oct 1.

Weill Cornell Medical College, New York, NY, USA.

View Article and Find Full Text PDF
October 2020

Outcomes of COVID-19 in patients with CLL: a multicenter international experience.

Authors:
Anthony R Mato Lindsey E Roeker Nicole Lamanna John N Allan Lori Leslie John M Pagel Krish Patel Anders Osterborg Daniel Wojenski Manali Kamdar Scott F Huntington Matthew S Davids Jennifer R Brown Darko Antic Ryan Jacobs Inhye E Ahn Jeffrey Pu Krista M Isaac Paul M Barr Chaitra S Ujjani Mark B Geyer Ellin Berman Andrew D Zelenetz Nikita Malakhov Richard R Furman Michael Koropsak Neil Bailey Lotta Hanson Guilherme F Perini Shuo Ma Christine E Ryan Adrian Wiestner Craig A Portell Mazyar Shadman Elise A Chong Danielle M Brander Suchitra Sundaram Amanda N Seddon Erlene Seymour Meera Patel Nicolas Martinez-Calle Talha Munir Renata Walewska Angus Broom Harriet Walter Dima El-Sharkawi Helen Parry Matthew R Wilson Piers E M Patten José-Ángel Hernández-Rivas Fatima Miras Noemi Fernández Escalada Paola Ghione Chadi Nabhan Sonia Lebowitz Erica Bhavsar Javier López-Jiménez Daniel Naya Jose Antonio Garcia-Marco Sigrid S Skånland Raul Cordoba Toby A Eyre

Blood 2020 09;136(10):1134-1143

Department of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

View Article and Find Full Text PDF
September 2020

Ibrutinib Treatment for First-Line and Relapsed/Refractory Chronic Lymphocytic Leukemia: Final Analysis of the Pivotal Phase Ib/II PCYC-1102 Study.

Authors:
John C Byrd Richard R Furman Steven E Coutre Ian W Flinn Jan A Burger Kristie Blum Jeff P Sharman William Wierda Weiqiang Zhao Nyla A Heerema Ying Luan Emily A Liu James P Dean Susan O'Brien

Clin Cancer Res 2020 Aug 24;26(15):3918-3927. Epub 2020 Mar 24.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article and Find Full Text PDF
August 2020

Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results.

Authors:
John C Byrd William G Wierda Anna Schuh Stephen Devereux Jorge M Chaves Jennifer R Brown Peter Hillmen Peter Martin Farrukh T Awan Deborah M Stephens Paolo Ghia Jacqueline Barrientos John M Pagel Jennifer A Woyach Kathleen Burke Todd Covey Michael Gulrajani Ahmed Hamdy Raquel Izumi Melanie M Frigault Priti Patel Wayne Rothbaum Min Hui Wang Susan O'Brien Richard R Furman

Blood 2020 04;135(15):1204-1213

Weill Cornell Medicine, NewYork-Presbyterian Hospital, New York, NY.

View Article and Find Full Text PDF
April 2020

Acalabrutinib monotherapy in patients with Waldenström macroglobulinemia: a single-arm, multicentre, phase 2 study.

Authors:
Roger G Owen Helen McCarthy Simon Rule Shirley D'Sa Sheeba K Thomas Olivier Tournilhac Francesco Forconi Marie José Kersten Pier Luigi Zinzani Sunil Iyengar Jaimal Kothari Monique C Minnema Efstathios Kastritis Thérèse Aurran-Schleinitz Bruce D Cheson Harriet Walter Daniel Greenwald Dih-Yih Chen Melanie M Frigault Ahmed Hamdy Raquel Izumi Priti Patel Helen Wei Sun Ku Lee Diana Mittag Richard R Furman

Lancet Haematol 2020 Feb 19;7(2):e112-e121. Epub 2019 Dec 19.

Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA.

View Article and Find Full Text PDF
February 2020

Correction: Bidirectional linkage between the B-cell receptor and NOTCH1 in chronic lymphocytic leukemia and in Richter's syndrome: therapeutic implications.

Authors:
Francesca Arruga Valeria Bracciamà Nicoletta Vitale Tiziana Vaisitti Katiuscia Gizzi Alison Yeomans Marta Coscia Giovanni D'Arena Gianluca Gaidano John N Allan Richard R Furman Graham Packham Francesco Forconi Silvia Deaglio

Leukemia 2020 Jun;34(6):1721

Department of Medical Sciences, University of Turin, Turin, Italy.

View Article and Find Full Text PDF
June 2020

Chronic lymphocytic leukemia with TP53 gene alterations: a detailed clinicopathologic analysis.

Authors:
Yen-Chun Liu Elizabeth Margolskee John N Allan Susan Mathew Erica Bhavsar Joseph Casano Attilio Orazi Richard R Furman Julia T Geyer

Mod Pathol 2020 03 2;33(3):344-353. Epub 2019 Sep 2.

Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.

View Article and Find Full Text PDF
March 2020

Bidirectional linkage between the B-cell receptor and NOTCH1 in chronic lymphocytic leukemia and in Richter's syndrome: therapeutic implications.

Authors:
Francesca Arruga Valeria Bracciamà Nicoletta Vitale Tiziana Vaisitti Katiuscia Gizzi Alison Yeomans Marta Coscia Giovanni D'Arena Gianluca Gaidano John N Allan Richard R Furman Graham Packham Francesco Forconi Silvia Deaglio

Leukemia 2020 02 29;34(2):462-477. Epub 2019 Aug 29.

Department of Medical Sciences, University of Turin, Turin, Italy.

View Article and Find Full Text PDF
February 2020

The impact of complex karyotype on the overall survival of patients with relapsed chronic lymphocytic leukemia treated with idelalisib plus rituximab.

Authors:
Karl-Anton Kreuzer Richard R Furman Stephan Stilgenbauer Ronald L Dubowy Yeonhee Kim Veerendra Munugalavadla Esther Lilienweiss Hans Christian Reinhardt Paula Cramer Barbara Eichhorst Peter Hillmen Susan M O'Brien Andrew R Pettitt Michael Hallek

Leukemia 2020 01 19;34(1):296-300. Epub 2019 Aug 19.

Department I of Internal Medicine, University of Cologne, Cologne, Germany.

View Article and Find Full Text PDF
January 2020

Long-term safety of single-agent ibrutinib in patients with chronic lymphocytic leukemia in 3 pivotal studies.

Authors:
Steven E Coutre John C Byrd Peter Hillmen Jacqueline C Barrientos Paul M Barr Stephen Devereux Tadeusz Robak Thomas J Kipps Anna Schuh Carol Moreno Richard R Furman Jan A Burger Michael O'Dwyer Paolo Ghia Rudolph Valentino Stephen Chang James P Dean Danelle F James Susan M O'Brien

Blood Adv 2019 06;3(12):1799-1807

Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA.

View Article and Find Full Text PDF
June 2019

Prognostic risk score for patients with relapsed or refractory chronic lymphocytic leukaemia treated with targeted therapies or chemoimmunotherapy: a retrospective, pooled cohort study with external validations.

Authors:
Jacob D Soumerai Ai Ni Mohamed Darif Anil Londhe Guan Xing Yong Mun Neil E Kay Tait D Shanafelt Kari G Rabe John C Byrd Asher A Chanan-Khan Richard R Furman Peter Hillmen Jeffrey Jones John F Seymour Jeffrey P Sharman Lucille Ferrante Mehrdad Mobasher Thomas Stark Vijay Reddy Lyndah K Dreiling Pankaj Bhargava Angela Howes Danelle F James Andrew D Zelenetz

Lancet Haematol 2019 Jul 17;6(7):e366-e374. Epub 2019 May 17.

Memorial-Sloan Kettering Cancer Center, New York, NY, USA.

View Article and Find Full Text PDF
July 2019

Acalabrutinib monotherapy in patients with chronic lymphocytic leukemia who are intolerant to ibrutinib.

Authors:
Farrukh T Awan Anna Schuh Jennifer R Brown Richard R Furman John M Pagel Peter Hillmen Deborah M Stephens Jennifer Woyach Elena Bibikova Prista Charuworn Melanie M Frigault Ahmed Hamdy Raquel Izumi Bolan Linghu Priti Patel Min Hui Wang John C Byrd

Blood Adv 2019 05;3(9):1553-1562

The Ohio State University Comprehensive Cancer Center, Columbus, OH.

View Article and Find Full Text PDF
May 2019

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.

Authors:
Alessandro Pastore Federico Gaiti Sydney X Lu Ryan M Brand Scott Kulm Ronan Chaligne Hongcang Gu Kevin Y Huang Elena K Stamenova Wendy Béguelin Yanwen Jiang Rafael C Schulman Kyu-Tae Kim Alicia Alonso John N Allan Richard R Furman Andreas Gnirke Catherine J Wu Ari M Melnick Alexander Meissner Bradley E Bernstein Omar Abdel-Wahab Dan A Landau

Nat Commun 2019 04 23;10(1):1874. Epub 2019 Apr 23.

New York Genome Center, New York, 10013, NY, USA.

View Article and Find Full Text PDF
April 2019

Final Results of a Randomized, Phase III Study of Rituximab With or Without Idelalisib Followed by Open-Label Idelalisib in Patients With Relapsed Chronic Lymphocytic Leukemia.

Authors:
Jeff P Sharman Steven E Coutre Richard R Furman Bruce D Cheson John M Pagel Peter Hillmen Jacqueline C Barrientos Andrew D Zelenetz Thomas J Kipps Ian W Flinn Paolo Ghia Herbert Eradat Thomas Ervin Nicole Lamanna Bertrand Coiffier Andrew R Pettitt Shuo Ma Eugen Tausch Paula Cramer Julie Huang Siddhartha Mitra Michael Hallek Susan M O'Brien Stephan Stilgenbauer

J Clin Oncol 2019 06 17;37(16):1391-1402. Epub 2019 Apr 17.

18 Ulm University, Ulm, Germany.

View Article and Find Full Text PDF
June 2019

Utility of positron emission tomography-computed tomography in patients with chronic lymphocytic leukemia following B-cell receptor pathway inhibitor therapy.

Authors:
Anthony R Mato William G Wierda Matthew S Davids Bruce D Cheson Steven E Coutre Michael Choi Richard R Furman Leonard Heffner Paul M Barr Herbert Eradat Sharanya M Ford Lang Zhou Maria Verdugo Rod A Humerickhouse Jalaja Potluri John C Byrd

Haematologica 2019 11 28;104(11):2258-2264. Epub 2019 Mar 28.

The Ohio State University, Columbus, OH, USA.

View Article and Find Full Text PDF
November 2019

Phase 1b study of venetoclax-obinutuzumab in previously untreated and relapsed/refractory chronic lymphocytic leukemia.

Authors:
Ian W Flinn John G Gribben Martin J S Dyer William Wierda Michael B Maris Richard R Furman Peter Hillmen Kerry A Rogers Swaminathan Padmanabhan Iyer Anne Quillet-Mary Loic Ysebaert Harriet S Walter Maria Verdugo Christian Klein Huang Huang Yanwen Jiang Gerard Lozanski Daniela Soriano Pignataro Kathryn Humphrey Mehrdad Mobasher Thomas J Kipps

Blood 2019 06 12;133(26):2765-2775. Epub 2019 Mar 12.

School of Medicine, University of California, San Diego, CA.

View Article and Find Full Text PDF
June 2019

Long-term follow-up of the RESONATE phase 3 trial of ibrutinib vs ofatumumab.

Authors:
John C Byrd Peter Hillmen Susan O'Brien Jacqueline C Barrientos Nishitha M Reddy Steven Coutre Constantine S Tam Stephen P Mulligan Ulrich Jaeger Paul M Barr Richard R Furman Thomas J Kipps Patrick Thornton Carol Moreno Marco Montillo John M Pagel Jan A Burger Jennifer A Woyach Sandra Dai Remus Vezan Danelle F James Jennifer R Brown

Blood 2019 05 6;133(19):2031-2042. Epub 2019 Mar 6.

CLL Center, Dana-Farber Cancer Institute, Boston, MA.

View Article and Find Full Text PDF
May 2019

Tumour debulking and reduction in predicted risk of tumour lysis syndrome with single-agent ibrutinib in patients with chronic lymphocytic leukaemia.

Authors:
William G Wierda John C Byrd Susan O'Brien Steven Coutre Paul M Barr Richard R Furman Thomas J Kipps Jan A Burger Don A Stevens Jeff Sharman Paolo Ghia Ian W Flinn Cathy Zhou Joi Ninomoto Danelle F James Constantine S Tam

Br J Haematol 2019 07 10;186(1):184-188. Epub 2019 Feb 10.

Peter MacCallum Cancer Centre and St. Vincent's Hospital, Melbourne, Australia.

View Article and Find Full Text PDF
July 2019

Current trends in the management of Richter's syndrome.

Authors:
John N Allan Richard R Furman

Int J Hematol Oncol 2018 Dec 8;7(4):IJH09. Epub 2019 Jan 8.

Department of Medicine, Division of Hematology & Medical Oncology, New York-Presbyterian Hospital, Weill Cornell Medicine, 525 East 68th Street, New York, NY 10065, USA.

View Article and Find Full Text PDF
December 2018

A rare colonic manifestation of chronic lymphocytic leukemia.

Authors:
Yunseok Namn Richard R Furman Carl Crawford

Leuk Lymphoma 2019 01 29;60(1):226-229. Epub 2018 Nov 29.

c Division of Gastroenterology and Hepatology , New York Presbyterian Hospital and Weill Cornell Medical Center , New York , USA.

View Article and Find Full Text PDF
January 2019

Venetoclax for chronic lymphocytic leukaemia patients who progress after more than one B-cell receptor pathway inhibitor.

Authors:
William G Wierda John C Byrd Matthew S Davids Richard R Furman Bruce D Cheson Paul M Barr Herbert Eradat Leonard Heffner Lang Zhou Maria Verdugo Jalaja Potluri Michael Choi

Br J Haematol 2019 06 27;185(5):961-966. Epub 2018 Nov 27.

University of California San Diego, San Diego, CA.

View Article and Find Full Text PDF
June 2019

Evaluation of the CLL-IPI in relapsed and refractory chronic lymphocytic leukemia in idelalisib phase-3 trials.

Authors:
Jacob D Soumerai Ai Ni Guan Xing Julie Huang Richard R Furman Jeffrey Jones Jeffrey P Sharman Michael Hallek Adeboye H Adewoye Ronald Dubowy Lyndah Dreiling Andrew D Zelenetz

Leuk Lymphoma 2019 06 8;60(6):1438-1446. Epub 2018 Nov 8.

b Memorial-Sloan Kettering Cancer Center , New York , NY , USA.

View Article and Find Full Text PDF
June 2019

Five-year follow-up of lenalidomide plus rituximab as initial treatment of mantle cell lymphoma.

Authors:
Jia Ruan Peter Martin Paul Christos Leandro Cerchietti Wayne Tam Bijal Shah Stephen J Schuster Amelyn Rodriguez David Hyman Maria Nieves Calvo-Vidal Sonali M Smith Jakub Svoboda Richard R Furman Morton Coleman John P Leonard

Blood 2018 11 4;132(19):2016-2025. Epub 2018 Sep 4.

Division of Hematology and Medical Oncology.

View Article and Find Full Text PDF
November 2018

Outcomes of front-line ibrutinib treated CLL patients excluded from landmark clinical trial.

Authors:
Anthony R Mato Lindsey E Roeker John N Allan John M Pagel Danielle M Brander Brian T Hill Bruce D Cheson Richard R Furman Nicole Lamanna Constantine S Tam Sasanka Handunnetti Ryan Jacobs Frederick Lansigan Erica Bhavsar Paul M Barr Mazyar Shadman Alan P Skarbnik Andre Goy Douglas F Beach Jakub Svoboda Jeffrey J Pu Alison R Sehgal Clive S Zent Hande H Tuncer Stephen J Schuster Peter V Pickens Nirav N Shah Joanna Rhodes Chaitra S Ujjani Chadi Nabhan

Am J Hematol 2018 11 26;93(11):1394-1401. Epub 2018 Sep 26.

Cardinal Health, Dublin, Ohio.

View Article and Find Full Text PDF
November 2018

Real-world outcomes and management strategies for venetoclax-treated chronic lymphocytic leukemia patients in the United States.

Authors:
Anthony R Mato Meghan Thompson John N Allan Danielle M Brander John M Pagel Chaitra S Ujjani Brian T Hill Nicole Lamanna Frederick Lansigan Ryan Jacobs Mazyar Shadman Alan P Skarbnik Jeffrey J Pu Paul M Barr Alison R Sehgal Bruce D Cheson Clive S Zent Hande H Tuncer Stephen J Schuster Peter V Pickens Nirav N Shah Andre Goy Allison M Winter Christine Garcia Kaitlin Kennard Krista Isaac Colleen Dorsey Lisa M Gashonia Arun K Singavi Lindsey E Roeker Andrew Zelenetz Annalynn Williams Christina Howlett Hanna Weissbrot Naveed Ali Sirin Khajavian Andrea Sitlinger Eve Tranchito Joanna Rhodes Joshua Felsenfeld Neil Bailey Bhavisha Patel Timothy F Burns Melissa Yacur Mansi Malhotra Jakub Svoboda Richard R Furman Chadi Nabhan

Haematologica 2018 09 7;103(9):1511-1517. Epub 2018 Jun 7.

Cardinal Health, Dublin, OH, USA.

View Article and Find Full Text PDF
September 2018

Evaluation of 230 patients with relapsed/refractory deletion 17p chronic lymphocytic leukaemia treated with ibrutinib from 3 clinical trials.

Authors:
Jeffrey Jones Anthony Mato Steven Coutre John C Byrd Richard R Furman Peter Hillmen Anders Osterborg Constantine Tam Stephan Stilgenbauer William G Wierda Nyla A Heerema Karl Eckert Fong Clow Cathy Zhou Alvina D Chu Danelle F James Susan M O'Brien

Br J Haematol 2018 08 5;182(4):504-512. Epub 2018 Jun 5.

Chao Family Comprehensive Cancer Center, University of California, Irvine, CA, USA.

View Article and Find Full Text PDF
August 2018

Novel Richter Syndrome Xenograft Models to Study Genetic Architecture, Biology, and Therapy Responses.

Authors:
Tiziana Vaisitti Esteban Braggio John N Allan Francesca Arruga Sara Serra Alberto Zamò Wayne Tam Amy Chadburn Richard R Furman Silvia Deaglio

Cancer Res 2018 07 7;78(13):3413-3420. Epub 2018 May 7.

Department of Medical Sciences, University of Turin, Italy.

View Article and Find Full Text PDF
July 2018

Idelalisib in Combination With Rituximab or Bendamustine or Both in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia.

Authors:
Steven E Coutre Ian W Flinn Sven de Vos Jacqueline C Barrientos Marshall T Schreeder Nina D Wagner-Johnson Jeff P Sharman Thomas E Boyd Nathan Fowler Lyndah Dreiling Yeonhee Kim Siddhartha Mitra Kanti Rai John P Leonard Richard R Furman

Hemasphere 2018 Jun 25;2(3):e39. Epub 2018 Apr 25.

Weill Cornell Medical College, New York, NY, USA.

View Article and Find Full Text PDF
June 2018