Richard P Phipps

Richard P Phipps

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Richard P Phipps

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Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor.

PLoS One 2019 19;14(9):e0222779. Epub 2019 Sep 19.

Flaum Eye Institute, School of Medicine and Dentistry, University of Rochester, Rochester, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0222779PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752849PMC
September 2019

Total plasma heme concentration increases after red blood cell transfusion and predicts mortality in critically ill medical patients.

Transfusion 2019 Jun 27;59(6):2007-2015. Epub 2019 Feb 27.

Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York.

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http://dx.doi.org/10.1111/trf.15218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548617PMC
June 2019

Thy1 (CD90) expression is regulated by DNA methylation during adipogenesis.

FASEB J 2019 Mar 30;33(3):3353-3363. Epub 2018 Oct 30.

Clinical and Translational Science Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.

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https://www.fasebj.org/doi/10.1096/fj.201801481R
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http://dx.doi.org/10.1096/fj.201801481RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404567PMC
March 2019

Lipoxin B Enhances Human Memory B Cell Antibody Production via Upregulating Cyclooxygenase-2 Expression.

J Immunol 2018 12 22;201(11):3343-3351. Epub 2018 Oct 22.

Department of Microbiology and Immunology, University of Rochester, Rochester, NY 14642;

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http://dx.doi.org/10.4049/jimmunol.1700503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246818PMC
December 2018

The HIV protease inhibitor, ritonavir, dysregulates human platelet function in vitro.

Thromb Res 2018 09 6;169:96-104. Epub 2018 Jul 6.

Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Box 608, Rochester, NY 14642, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174677PMC
September 2018

Thy1 is a positive regulator of osteoblast differentiation and modulates bone homeostasis in obese mice.

FASEB J 2018 06 17;32(6):3174-3183. Epub 2018 Jan 17.

Division of Allergy, Immunology, and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA.

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http://dx.doi.org/10.1096/fj.201701379RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956243PMC
June 2018

Evaluating a Variable Porosity Wound Dressing With Anti-Scar Properties in a Porcine Model of Wound Healing.

Eplasty 2018 24;18:e20. Epub 2018 May 24.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981775PMC
May 2018

In Vitro Characterization of Variable Porosity Wound Dressing With Anti-Scar Properties.

Eplasty 2018 25;18:e21. Epub 2018 May 25.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981800PMC
May 2018

In Vitro Methods to Characterize the Effects of Tobacco and Nontobacco Products on Human Platelet Function.

Curr Protoc Toxicol 2018 05;76(1):e46

Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York.

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http://dx.doi.org/10.1002/cptx.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082021PMC
May 2018

Activated human T lymphocytes inhibit TGFβ-induced fibroblast to myofibroblast differentiation via prostaglandins D and E.

Am J Physiol Lung Cell Mol Physiol 2018 04 20;314(4):L569-L582. Epub 2017 Dec 20.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry , Rochester, New York.

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http://dx.doi.org/10.1152/ajplung.00565.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966783PMC
April 2018

Cigarette smoke dampens antiviral signaling in small airway epithelial cells by disrupting TLR3 cleavage.

Am J Physiol Lung Cell Mol Physiol 2018 03 14;314(3):L505-L513. Epub 2017 Dec 14.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry , Rochester, New York.

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http://dx.doi.org/10.1152/ajplung.00406.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900359PMC
March 2018

Management of Platelet Disorders and Platelet Transfusions in ICU Patients.

Transfus Med Rev 2017 10 4;31(4):252-257. Epub 2017 May 4.

Pulmonary and Critical Care, Department of Medicine, Strong Memorial Hospital and Golisano Children's Hospital, University of Rochester Medical Center, Rochester, NY.

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http://dx.doi.org/10.1016/j.tmrv.2017.04.002DOI Listing
October 2017

Comparison of in vitro toxicological effects of biomass smoke from different sources of animal dung.

Toxicol In Vitro 2017 Sep 30;43:76-86. Epub 2017 May 30.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States; Division of Pulmonary and Critical Care Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States; Lung Biology and Disease Program, University of Rochester, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2017.05.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736384PMC
September 2017

Development of an accurate and sensitive method for lactate analysis in exhaled breath condensate by LC MS/MS.

J Chromatogr B Analyt Technol Biomed Life Sci 2017 Sep 24;1061-1062:468-473. Epub 2017 Jul 24.

Department of Medicine, University of Rochester Medical Center, United States.

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http://dx.doi.org/10.1016/j.jchromb.2017.07.041DOI Listing
September 2017

Antifibrotic Actions of Peroxisome Proliferator-Activated Receptor γ Ligands in Corneal Fibroblasts Are Mediated by β-Catenin-Regulated Pathways.

Am J Pathol 2017 Aug 10;187(8):1660-1669. Epub 2017 Jun 10.

Flaum Eye Institute, University of Rochester, Rochester, New York; Center for Visual Science, University of Rochester, Rochester, New York. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530905PMC
August 2017

Thy1 (CD90) Expression Is Elevated in Radiation-Induced Periprosthetic Capsular Contracture: Implication for Novel Therapeutics.

Plast Reconstr Surg 2017 Aug;140(2):316-326

Rochester, N.Y. From the Departments of Medicine and Environmental Medicine and the Division of Plastic Surgery, School of Medicine and Dentistry, University of Rochester.

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http://dx.doi.org/10.1097/PRS.0000000000003542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531053PMC
August 2017

Editor's Highlight: Thy1 (CD90) Expression is Reduced by the Environmental Chemical Tetrabromobisphenol-A to Promote Adipogenesis Through Induction of microRNA-103.

Toxicol Sci 2017 06;157(2):305-319

Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA.

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http://dx.doi.org/10.1093/toxsci/kfx046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075632PMC
June 2017

and Approaches to Evaluate Next-Generation Tobacco and Non-Tobacco Products on Human Blood Platelets.

Appl In Vitro Toxicol 2017 Mar;3(1):110-120

Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.; Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.; Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York.

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http://dx.doi.org/10.1089/aivt.2016.0034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338183PMC
March 2017

Dung biomass smoke activates inflammatory signaling pathways in human small airway epithelial cells.

Am J Physiol Lung Cell Mol Physiol 2016 Dec 11;311(6):L1222-L1233. Epub 2016 Nov 11.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York;

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http://dx.doi.org/10.1152/ajplung.00183.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206396PMC
December 2016

The Aryl Hydrocarbon Receptor and Its Ligands Inhibit Myofibroblast Formation and Activation: Implications for Thyroid Eye Disease.

Am J Pathol 2016 12 11;186(12):3189-3202. Epub 2016 Nov 11.

Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York; Flaum Eye Institute, School of Medicine and Dentistry, University of Rochester, Rochester, New York. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225292PMC
December 2016

A Role for Bradykinin Signaling in Chronic Vulvar Pain.

J Pain 2016 11 18;17(11):1183-1197. Epub 2016 Aug 18.

Department of Environmental Medicine, University of Rochester, Rochester, New York; Department of Obstetrics and Gynecology, University of Rochester, Rochester, New York; Department of Microbiology and Immunology, University of Rochester, Rochester, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jpain.2016.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226004PMC
November 2016

Human lung fibroblasts produce proresolving peroxisome proliferator-activated receptor-γ ligands in a cyclooxygenase-2-dependent manner.

Am J Physiol Lung Cell Mol Physiol 2016 Nov 9;311(5):L855-L867. Epub 2016 Sep 9.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York;

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http://dx.doi.org/10.1152/ajplung.00272.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130533PMC
November 2016

Resolvin D2 decreases TLR4 expression to mediate resolution in human monocytes.

FASEB J 2016 09 2;30(9):3181-93. Epub 2016 Jun 2.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA; and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA

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http://dx.doi.org/10.1096/fj.201600375RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001508PMC
September 2016

Introduction to Department of Defense Research on Burn Pits, Biomarkers, and Health Outcomes Related to Deployment in Iraq and Afghanistan.

J Occup Environ Med 2016 08;58(8 Suppl 1):S3-S11

Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon); 779th Aerospace Medical Squadron, 79th Medical WingJoint Base Andrews, Maryland (Dr Rohrbeck); Bioenvironmental Engineering Flight Commander, 30th Medical Group, 338 South Dakota Ave, Vandenberg AFB, CA 93437 (Maj Haines); Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Atlanta, Georgia (Dr Jones, Mr Walker); Departments of Medicine and Environmental Medicine, University of Rochester Medical Center (Drs Utell, Phipps, Thatcher, Woeller); Center for Air Resources Engineering and Science, Institute for a Sustainable Environment, Clarkson University, Potsdam, New York (Dr Hopke); U.S Army Center for Public Health (Provisional), Aberdeen Proving Ground (Drs Baird, Gaydos); and Anatomy and Cell Biology, Uniformed Services University, Bethesda, Maryland (Drs Pollard, Dalgard).

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http://dx.doi.org/10.1097/JOM.0000000000000775DOI Listing
August 2016

Pilot Metabolome-Wide Association Study of Benzo(a)pyrene in Serum From Military Personnel.

J Occup Environ Med 2016 08;58(8 Suppl 1):S44-52

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, Georgia (Mr Walker, Drs Uppal and Jones); Department of Civil and Environmental Engineering, Tufts University, Medford, Massachusetts (Mr Walker, Dr Pennell); Center for Air Resources Engineering and Science, Clarkson University, Potsdam (Drs Xia, Hopke); Pulmonary Division, Department of Medicine (Drs Utell, Phipps, Sime), Department of Environmental Medicine, University of Rochester Medical Center, New York (Drs Utell, Phipps, Sime); 779th Aerospace Medicine Squadron, 79th Medical Wing, Joint Base Andrews, MD (Dr Rohrbeck); and Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon).

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http://dx.doi.org/10.1097/JOM.0000000000000772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837056PMC
August 2016

Detection of Serum microRNAs From Department of Defense Serum Repository: Correlation With Cotinine, Cytokine, and Polycyclic Aromatic Hydrocarbon Levels.

J Occup Environ Med 2016 08;58(8 Suppl 1):S62-71

Department of Environmental Medicine (Dr Woeller, Mr Pollock, Ms Croasdell, Ms Kim, Dr Utell, Dr Phipps), Department of Medicine (Drs Thatcher, Utell, and Phipps), Microbiology and Immunology, University of Rochester Medical Center (Mr Van Twisk, Drs Thakar and Phipps); Center for Air Resources Engineering and Science, Clarkson University, Potsdam, New York (Drs Hopke and Xia); and Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD 20814 (Dr Mallon).

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http://dx.doi.org/10.1097/JOM.0000000000000742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661968PMC
August 2016

MicroRNAs as Novel Biomarkers of Deployment Status and Exposure to Polychlorinated Dibenzo-p-Dioxins/Dibenzofurans.

J Occup Environ Med 2016 08;58(8 Suppl 1):S89-96

Department of Environmental Medicine (Dr Woeller, Mr Pollock, Ms Croasdell, Dr Sime, Dr Utell, and Dr Phipps), Department of Medicine (Dr Thatcher, Dr Sime, Dr Utell, and Dr Phipps), Microbiology and Immunology (Mr Van Twisk, Dr Thakar, and Dr Phipps), and Department of Biostatistics and Computational Biology (Mr Van Twisk, Dr Thakar), University of Rochester Medical Center; Center for Air Resources Engineering and Science, Clarkson University, Potsdam, New York (Dr Hopke, Dr Xia); and Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon).

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http://dx.doi.org/10.1097/JOM.0000000000000769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978134PMC
August 2016

Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E2.

PLoS One 2015 6;10(8):e0135266. Epub 2015 Aug 6.

Lung Biology and Disease Program, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, United States of America; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, United States of America; Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, United States of America; Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester NY, 14642, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135266PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527711PMC
May 2016

Resveratrol preserves the function of human platelets stored for transfusion.

Br J Haematol 2016 Mar 18;172(5):794-806. Epub 2015 Dec 18.

Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.

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http://dx.doi.org/10.1111/bjh.13862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764392PMC
March 2016

Resolvin D1 Dampens Pulmonary Inflammation and Promotes Clearance of Nontypeable Haemophilus influenzae.

J Immunol 2016 Mar 3;196(6):2742-52. Epub 2016 Feb 3.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642; Lung Biology and Disease Program, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642; and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642

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http://dx.doi.org/10.4049/jimmunol.1502331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779746PMC
March 2016

Specialized proresolving mediators (SPMs) inhibit human B-cell IgE production.

Eur J Immunol 2016 Jan 2;46(1):81-91. Epub 2015 Nov 2.

Department of Microbiology and Immunology, University of Rochester, Rochester, NY, USA.

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http://dx.doi.org/10.1002/eji.201545673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710564PMC
January 2016

Endogenous ligands of the aryl hydrocarbon receptor regulate lung dendritic cell function.

Immunology 2016 Jan 10;147(1):41-54. Epub 2015 Nov 10.

Division of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY, USA.

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http://dx.doi.org/10.1111/imm.12540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693882PMC
January 2016

Pharmacologic inhibition of lactate production prevents myofibroblast differentiation.

Am J Physiol Lung Cell Mol Physiol 2015 Dec 25;309(11):L1305-12. Epub 2015 Sep 25.

University of Rochester Department of Medicine, Rochester, New York; University of Rochester Department of Environmental Medicine, Rochester, New York; and University of Rochester Lung Biology and Disease Program, Rochester, New York

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http://dx.doi.org/10.1152/ajplung.00058.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669339PMC
December 2015

Resolvin D1 Reduces Emphysema and Chronic Inflammation.

Am J Pathol 2015 Dec 24;185(12):3189-201. Epub 2015 Oct 24.

Lung Biology and Disease Program, University of Rochester School of Medicine and Dentistry, Rochester, New York; Division of Pulmonary and Critical Care Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York; Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729265PMC
December 2015

PPARγ and the Innate Immune System Mediate the Resolution of Inflammation.

PPAR Res 2015 2;2015:549691. Epub 2015 Dec 2.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA ; Lung Biology and Disease Program, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA ; Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1155/2015/549691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680113PMC
December 2015

Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages.

Am J Physiol Lung Cell Mol Physiol 2015 Oct 21;309(8):L888-901. Epub 2015 Aug 21.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York; Lung Biology and Disease Program, University of Rochester School of Medicine and Dentistry, Rochester, New York; Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York; and

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http://dx.doi.org/10.1152/ajplung.00125.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609942PMC
October 2015

Inhibitory effects of PPARγ ligands on TGF-β1-induced CTGF expression in cat corneal fibroblasts.

Exp Eye Res 2015 Sep 2;138:52-8. Epub 2015 Jul 2.

Flaum Eye Institute, University of Rochester, Rochester, NY, USA; Center for Visual Science, University of Rochester, Rochester, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2015.06.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553125PMC
September 2015

Microparticles engineered to highly express peroxisome proliferator-activated receptor-γ decreased inflammatory mediator production and increased adhesion of recipient monocytes.

PLoS One 2014 26;9(11):e113189. Epub 2014 Nov 26.

Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester, Rochester, United States of America; Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113189PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245109PMC
July 2015

Identification of novel mechanisms involved in generating localized vulvodynia pain.

Am J Obstet Gynecol 2015 Jul 12;213(1):38.e1-38.e12. Epub 2015 Feb 12.

Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, NY; Department of Obstetrics and Gynecology, School of Medicine and Dentistry, University of Rochester, Rochester, NY; Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester, Rochester, NY. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2015.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485605PMC
July 2015

The effects of aspirin on platelet function and lysophosphatidic acids depend on plasma concentrations of EPA and DHA.

Prostaglandins Leukot Essent Fatty Acids 2015 May 22;96:17-24. Epub 2014 Dec 22.

Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Albany, NY, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09523278140020
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http://dx.doi.org/10.1016/j.plefa.2014.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395522PMC
May 2015

Thy1 (CD90) controls adipogenesis by regulating activity of the Src family kinase, Fyn.

FASEB J 2015 Mar 21;29(3):920-31. Epub 2014 Nov 21.

*Department of Environmental Medicine and Flaum Eye Institute, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA

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http://dx.doi.org/10.1096/fj.14-257121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422356PMC
March 2015

Site-specific mesenchymal control of inflammatory pain to yeast challenge in vulvodynia-afflicted and pain-free women.

Pain 2015 Mar;156(3):386-96

Departments of aObstetrics and Gynecology bEnvironmental Medicine cPathology and Laboratory Medicine dMicrobiology and Immunology, and eBiostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA fAnesthesiology Research Laboratories, Department of Perioperative Medicine National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1097/01.j.pain.0000460320.95267.5dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378529PMC
March 2015

Breaking the mold: transcription factors in the anucleate platelet and platelet-derived microparticles.

Front Immunol 2015 13;6:48. Epub 2015 Feb 13.

Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry , Rochester, NY , USA ; Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry , Rochester, NY , USA ; Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry , Rochester, NY , USA.

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http://dx.doi.org/10.3389/fimmu.2015.00048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327621PMC
March 2015

Salinomycin and other polyether ionophores are a new class of antiscarring agent.

J Biol Chem 2015 Feb 23;290(6):3563-75. Epub 2014 Dec 23.

From the Department of Environmental Medicine and Flaum Eye Institute, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642

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http://dx.doi.org/10.1074/jbc.M114.601872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319023PMC
February 2015

Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation.

J Immunol 2015 Feb 24;194(3):863-7. Epub 2014 Dec 24.

Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115;

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http://dx.doi.org/10.4049/jimmunol.1402534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297713PMC
February 2015

Platelet transfusion - the new immunology of an old therapy.

Front Immunol 2015 2;6:28. Epub 2015 Feb 2.

Department of Pathology and Laboratory Medicine, School of Medicine and Dentistry, University of Rochester Medical Center , Rochester, NY , USA.

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http://dx.doi.org/10.3389/fimmu.2015.00028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313719PMC
February 2015

The specialized proresolving mediator 17-HDHA enhances the antibody-mediated immune response against influenza virus: a new class of adjuvant?

J Immunol 2014 Dec 12;193(12):6031-40. Epub 2014 Nov 12.

Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642; Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642;

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http://dx.doi.org/10.4049/jimmunol.1302795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258475PMC
December 2014

Resolvin D1 attenuates polyinosinic-polycytidylic acid-induced inflammatory signaling in human airway epithelial cells via TAK1.

J Immunol 2014 Nov 15;193(10):4980-7. Epub 2014 Oct 15.

Lung Biology and Disease Program, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642; and Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642

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http://dx.doi.org/10.4049/jimmunol.1400313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409010PMC
November 2014

The effects of aspirin and fish oil consumption on lysophosphatidylcholines and lysophosphatidic acids and their correlates with platelet aggregation in adults with diabetes mellitus.

Prostaglandins Leukot Essent Fatty Acids 2014 Feb-Mar;90(2-3):61-8. Epub 2013 Dec 18.

Department of Public Health Sciences, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09523278130023
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http://dx.doi.org/10.1016/j.plefa.2013.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939709PMC
October 2014

Mapracorat, a selective glucocorticoid receptor agonist, upregulates RelB, an anti-inflammatory nuclear factor-kappaB protein, in human ocular cells.

Exp Eye Res 2014 Oct;127:290-8

Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA; Department of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA; Environmental Medicine, Lung and Biology Disease Program, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA; Flaum Eye Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2014.07.013DOI Listing
October 2014

Removal of biologic response modifiers associated with platelet transfusion reactions: strategies worth considering?

Transfusion 2014 Oct;54(10):2583

GIMAP-EA3064, Université de Lyon, Saint-Étienne, France; INTS-Institut National de la Transfusion Sanguine, Paris, France.

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http://dx.doi.org/10.1111/trf.12811DOI Listing
October 2014

Thrombosis, platelets, microparticles and PAH: more than a clot.

Drug Discov Today 2014 Aug 18;19(8):1230-5. Epub 2014 Apr 18.

Aab Cardiovascular Research Institute and Division of Pulmonary and Critical Care Medicine, University of Rochester, 601 Elmwood Ave, Rochester, NY 14642, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386061PMC
August 2014

Drug discovery in pulmonary arterial hypertension: attacking the enigmatic root of a deadly weed.

Drug Discov Today 2014 Aug 21;19(8):1226-9. Epub 2014 Apr 21.

Department of Microbiology and Immunology, University of Rochester, Rochester, NY, USA; Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, NY, USA; Department of Environmental Medicine, University of Rochester, Rochester, NY, USA.

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http://dx.doi.org/10.1016/j.drudis.2014.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386059PMC
August 2014

Cigarette smoke exposure exacerbates lung inflammation and compromises immunity to bacterial infection.

J Immunol 2014 Jun 21;192(11):5226-35. Epub 2014 Apr 21.

Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263;

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http://dx.doi.org/10.4049/jimmunol.1302584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066560PMC
June 2014

Platelets and cancer-associated thrombosis.

Semin Oncol 2014 Jun 24;41(3):302-10. Epub 2014 Apr 24.

James P. Wilmot Cancer Center, Department of Medicine, and Division of Hematology/Oncology, University of Rochester, Rochester, NY.

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http://dx.doi.org/10.1053/j.seminoncol.2014.04.009DOI Listing
June 2014

SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism.

Am J Physiol Lung Cell Mol Physiol 2014 May 14;306(9):L816-28. Epub 2014 Mar 14.

Dept. of Environmental Medicine, Univ. of Rochester Medical Center, Box 850, 601 Elmwood Ave., Rochester, NY 14642.

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http://dx.doi.org/10.1152/ajplung.00323.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010647PMC
May 2014

Inhibitory effects of PPARγ ligands on TGF-β1-induced corneal myofibroblast transformation.

Am J Pathol 2014 May 17;184(5):1429-45. Epub 2014 Mar 17.

Flaum Eye Institute, University of Rochester, Rochester, New York; Center for Visual Science, University of Rochester, Rochester, New York. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.01.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005981PMC
May 2014

The triterpenoid CDDO-Me inhibits bleomycin-induced lung inflammation and fibrosis.

PLoS One 2013 31;8(5):e63798. Epub 2013 May 31.

The Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Rochester, Rochester, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063798PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669327PMC
February 2014

Orbital fibroblasts from thyroid eye disease patients differ in proliferative and adipogenic responses depending on disease subtype.

Invest Ophthalmol Vis Sci 2013 Nov 8;54(12):7370-7. Epub 2013 Nov 8.

Flaum Eye Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York.

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http://dx.doi.org/10.1167/iovs.13-12741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823547PMC
November 2013

The influence of Cox-2 and bioactive lipids on hematological cancers.

Curr Angiogenes 2013 Sep;2(2):135-142

Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642 ; Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642.

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http://dx.doi.org/10.2174/2211552802999140131105947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039176PMC
September 2013

Attenuation of inflammatory mediator production by the NF-κB member RelB is mediated by microRNA-146a in lung fibroblasts.

Am J Physiol Lung Cell Mol Physiol 2013 Jun 5;304(11):L774-81. Epub 2013 Apr 5.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1152/ajplung.00352.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680764PMC
June 2013

Alterations of platelet function and clot formation kinetics after in vitro exposure to anti-A and -B.

Transfusion 2013 Feb 25;53(2):382-93. Epub 2012 May 25.

Department of Pathology and Laboratory Medicine, the James P. Wilmot Cancer Center, University of Rochester, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1111/j.1537-2995.2012.03718.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566315PMC
February 2013

Transfusion immunomodulation--the case for leukoreduced and (perhaps) washed transfusions.

Blood Cells Mol Dis 2013 Jan 13;50(1):61-8. Epub 2012 Sep 13.

Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.

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http://dx.doi.org/10.1016/j.bcmd.2012.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508165PMC
January 2013

Platelets--to transfuse or not to transfuse.

Lancet 2012 Oct 8;380(9850):1287-9. Epub 2012 Aug 8.

Department of Pathology, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1016/S0140-6736(12)60983-0DOI Listing
October 2012

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases.

PPAR Res 2012 18;2012:705352. Epub 2012 Jun 18.

Division of Pulmonary and Critical Care, Department of Medicine, University of Rochester School of Medicine and Dentistry, Box 692, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1155/2012/705352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385049PMC
August 2012

Specialized proresolving mediators enhance human B cell differentiation to antibody-secreting cells.

J Immunol 2012 Jul 18;189(2):1036-42. Epub 2012 Jun 18.

Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

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http://dx.doi.org/10.4049/jimmunol.1103483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392531PMC
July 2012

Genetic ablation of the aryl hydrocarbon receptor causes cigarette smoke-induced mitochondrial dysfunction and apoptosis.

J Biol Chem 2011 Dec 7;286(50):43214-28. Epub 2011 Oct 7.

Research Institute of the McGill University Health Centre, McGill University, Montreal, Quebec H2X 2P2, Canada.

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http://dx.doi.org/10.1074/jbc.M111.258764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234839PMC
December 2011

Transglutaminase 2 and its role in pulmonary fibrosis.

Am J Respir Crit Care Med 2011 Sep 23;184(6):699-707. Epub 2011 Jun 23.

University of Rochester, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1164/rccm.201101-0013OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208598PMC
September 2011

Ocular fibroblast diversity: implications for inflammation and ocular wound healing.

Invest Ophthalmol Vis Sci 2011 Jul 1;52(7):4859-65. Epub 2011 Jul 1.

Department of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1167/iovs.10-7066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175934PMC
July 2011

Lung-targeted overexpression of the NF-κB member RelB inhibits cigarette smoke-induced inflammation.

Am J Pathol 2011 Jul 5;179(1):125-33. Epub 2011 May 5.

Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1016/j.ajpath.2011.03.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123857PMC
July 2011

Platelet Activation Following Exposure to Anti-ABO Antibodies-An In Vitro Study.

US Oncol Hematol 2011 Jan;7(1):72-74

Assistant Professor, Department of Medicine, University of Rochester Medical Center.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162317PMC
January 2011