Publications by authors named "Richard N Mitchell"

67Publications

Clinically isolated aortitis: imaging features and clinical outcomes: comparison with giant cell arteritis and giant cell aortitis.

Int J Cardiovasc Imaging 2020 Oct 30. Epub 2020 Oct 30.

Cardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article and Find Full Text PDF
October 2020

Pathobiology of cardiovascular diseases: an update.

Cardiovasc Pathol 2019 Sep - Oct;42:44-53. Epub 2019 Jun 14.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

View Article and Find Full Text PDF
December 2019

2019 Society for Cardiovascular Pathology Distinguished Achievement Award Recipient -- Gayle L. Winters, M.D.

Cardiovasc Pathol 2019 Sep - Oct;42:4-5. Epub 2019 May 6.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

View Article and Find Full Text PDF
November 2019

When More Is Less.

Circulation 2018 11;138(22):2527-2529

Department of Pathology, Brigham and Women's Hospital, Boston, MA.

View Article and Find Full Text PDF
November 2018

Enterovascular Fistula: An Under-Recognized Complication Related to Therapy for Esophageal Carcinoma.

J Laparoendosc Adv Surg Tech A 2019 May 18;29(5):583-588. Epub 2018 Dec 18.

Division of Thoracic Surgery, Department of Surgery, Maimonides Medical Center, Brooklyn, New York.

View Article and Find Full Text PDF
May 2019

Thrombus on the inflow cannula of the HeartWare HVAD: an update.

Cardiovasc Pathol 2019 Jan - Feb;38:14-20. Epub 2018 Sep 15.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115. Electronic address:

View Article and Find Full Text PDF
March 2019

True, true unrelated? Coexistence of Waldenström macroglobulinemia and cardiac transthyretin amyloidosis.

Haematologica 2018 08 19;103(8):e374-e376. Epub 2018 Apr 19.

Cardiac Amyloidosis Program, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA

View Article and Find Full Text PDF
August 2018

Genes in the Basement, Postmortem Genetic Testing…and 3 (New) Realities.

Circ Cardiovasc Genet 2017 12;10(6)

From the Department of Pathology, Centre for Heart and Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, Canada (M.A.S.); and Department of Pathology, Brigham and Women's Hospital, Boston, MA (R.N.M.).

View Article and Find Full Text PDF
December 2017

Passport to pathology: transforming the medical student pathology elective from a passive educational experience to an exciting, immersive clinical rotation.

Hum Pathol 2017 10 8;68:34-39. Epub 2017 Sep 8.

Department of Pathology Brigham and Women's Hospital Harvard Medical School, Boston, MA 02115. Electronic address:

View Article and Find Full Text PDF
October 2017

Improving undergraduate pathology teaching: medical students' perspective-reply.

Hum Pathol 2017 10 7;68:203-204. Epub 2017 Sep 7.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115. Electronic address:

View Article and Find Full Text PDF
October 2017

Winning the battle, but losing the war: mechanisms and morphology of cancer-therapy-associated cardiovascular toxicity.

Cardiovasc Pathol 2017 Sep - Oct;30:55-63. Epub 2017 Jun 30.

Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115. Electronic address:

View Article and Find Full Text PDF
May 2018

Use of Multimodality Imaging in Diagnosing Invasive Fungal Diseases of the Heart.

Circ Cardiovasc Imaging 2017 06;10(6)

From the Department of Medicine (E.M.D.), Cardiovascular Imaging Program, Departments of Medicine and Radiology (S.C., S.P., A.A., M.F.D., R.B.), Department of Pathology (C.G., R.N.M.), and Division of Infectious Disease, Department of Medicine (R.M.M.), Brigham and Women's Hospital, Boston, MA.

View Article and Find Full Text PDF
June 2017

Persistence and proliferation of human mesenchymal stromal cells in the right ventricular myocardium after intracoronary injection in a large animal model of pulmonary hypertension.

Cytotherapy 2017 06 6;19(6):668-679. Epub 2017 Apr 6.

Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

View Article and Find Full Text PDF
June 2017

Giant cell aortitis mimicking intramural hematoma.

J Cardiovasc Comput Tomogr 2017 Jul - Aug;11(4):327-328. Epub 2017 Feb 4.

Cardiovascular Imaging Program, Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, United States.

View Article and Find Full Text PDF
November 2018

Characterization of the Changes in Cardiac Structure and Function in Mice Treated With Anthracyclines Using Serial Cardiac Magnetic Resonance Imaging.

Circ Cardiovasc Imaging 2016 Dec;9(12)

From the Non-Invasive Cardiovascular Imaging Program and the Cardiovascular Division, Department of Medicine (H.F., S.A.A., R.V.S., R.Y.K.), Department of Pathology (R.N.M.), and Department of Radiology (M.J.-H.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Faculty of Medical Science, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil (O.R.C.-F.); and Cardiac MR PET CT Program, Division of Radiology (P.V.S., D.A., B.S., U.H., T.G.N.) and Division of Cardiology, Department of Medicine (M.S.-C., T.G.N.), Massachusetts General Hospital, Harvard Medical School, Boston, MA.

View Article and Find Full Text PDF
December 2016

Heart failure therapies: new strategies for old treatments and new treatments for old strategies.

Cardiovasc Pathol 2016 Nov - Dec;25(6):503-511. Epub 2016 Aug 29.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article and Find Full Text PDF
January 2017

Case report and literature review: cardiac tamponade as a complication of pericardial extramedullary hematopoiesis.

Cardiovasc Pathol 2016 Sep-Oct;25(5):371-4. Epub 2016 May 30.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

View Article and Find Full Text PDF
January 2017

Using exit competencies to integrate pathology into the undergraduate clinical clerkships.

Hum Pathol 2016 Jan 21;47(1):1-3. Epub 2015 Sep 21.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115. Electronic address:

View Article and Find Full Text PDF
January 2016

Osseous and chondromatous metaplasia in calcific aortic valve stenosis.

Cardiovasc Pathol 2016 Jan-Feb;25(1):18-24. Epub 2015 Aug 29.

Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 02215, USA.

View Article and Find Full Text PDF
October 2016

A sensitive chemotaxis assay using a novel microfluidic device.

Biomed Res Int 2013 14;2013:373569. Epub 2013 Sep 14.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA ; Department of Hepatobiliary Surgery, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.

View Article and Find Full Text PDF
June 2014

Cardiac allograft involvement by post-transplantation lymphoproliferative disorder.

J Am Coll Cardiol 2013 Sep 10;62(10):937. Epub 2013 Jul 10.

Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

View Article and Find Full Text PDF
September 2013

Learning from rejection: what transplantation teaches us about (other) vascular pathologies.

J Autoimmun 2013 Sep 3;45:80-9. Epub 2013 Jul 3.

Pathology and Health Sciences and Technology, Harvard Medical School and Brigham and Women's Hospital, 77 Avenue Louis Pasteur/NRB 730D, Boston, MA 02115, USA. Electronic address:

View Article and Find Full Text PDF
September 2013

Surgical Pathology of Small- and Medium-Sized Vessels.

Surg Pathol Clin 2012 Jun 1;5(2):435-51. Epub 2012 May 1.

Department of Pathology, Brigham & Women's Hospital/Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

View Article and Find Full Text PDF
June 2012

Plaque attack: one hundred years of atherosclerosis in The American Journal of Pathology.

Am J Pathol 2012 Jun 29;180(6):2184-7. Epub 2012 Apr 29.

Department of Pathology, School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.

View Article and Find Full Text PDF
June 2012

Loss of myeloid related protein-8/14 exacerbates cardiac allograft rejection.

Circulation 2011 Dec 5;124(25):2920-32. Epub 2011 Dec 5.

Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, NRB7, Boston, MA 02115, USA.

View Article and Find Full Text PDF
December 2011

Adiponectin inhibits allograft rejection in murine cardiac transplantation.

Transplantation 2009 Oct;88(7):879-83

Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article and Find Full Text PDF
October 2009

CC chemokine receptor-1 activates intimal smooth muscle-like cells in graft arterial disease.

Circulation 2009 Nov 19;120(18):1800-13. Epub 2009 Oct 19.

Donald W. Reynolds Cardiovascular Clinical Research Center, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

View Article and Find Full Text PDF
November 2009

The role of chemokines in transplant graft arterial disease.

Arterioscler Thromb Vasc Biol 2008 Nov 18;28(11):1937-49. Epub 2008 Sep 18.

Department of Pathology, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article and Find Full Text PDF
November 2008

Graft vascular disease: immune response meets the vessel wall.

Annu Rev Pathol 2009 ;4:19-47

Department of Pathology, Health Sciences and Technology, Brigham and Women's Hospital and Harvard Medical School , Boston, MA 02115, USA.

View Article and Find Full Text PDF
May 2009

Leukocyte integrin Mac-1 promotes acute cardiac allograft rejection.

Circulation 2008 Apr 31;117(15):1997-2008. Epub 2008 Mar 31.

Donald W. Reynolds Cardiovascular Clinical Research Center, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02115, USA.

View Article and Find Full Text PDF
April 2008

Burn-induced immunosuppression: attenuated T cell signaling independent of IFN-gamma- and nitric oxide-mediated pathways.

J Leukoc Biol 2008 Feb 16;83(2):305-13. Epub 2007 Nov 16.

The Surgical Services/Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

View Article and Find Full Text PDF
February 2008

Vascular remodeling in transplant vasculopathy.

Circ Res 2007 Apr;100(7):967-78

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 77 Ave Louis Pasteur, Boston, MA 02115, USA.

View Article and Find Full Text PDF
April 2007

Inflammation and cellular immune responses in abdominal aortic aneurysms.

Arterioscler Thromb Vasc Biol 2006 May 23;26(5):987-94. Epub 2006 Feb 23.

The Donald W. Reynolds Cardiovascular Clinical Research Center, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

View Article and Find Full Text PDF
May 2006

Protecting the pump: controlling myocardial inflammatory responses.

Annu Rev Physiol 2006 ;68:67-95

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article and Find Full Text PDF
June 2006

Characterization of smooth muscle-like cells in circulating human peripheral blood.

Atherosclerosis 2006 Aug 25;187(2):351-62. Epub 2005 Oct 25.

Department of Cardiovascular Medicine, Graduate School of Medical Science, Kumamoto University, Japan.

View Article and Find Full Text PDF
August 2006

Cardiogenic shock and peripheral eosinophilia in a young woman.

Ann Allergy Asthma Immunol 2005 Sep;95(3):229-33

Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

View Article and Find Full Text PDF
September 2005

The role of stem cells in the response to myocardial and vascular wall injury.

Cardiovasc Pathol 2005 Sep-Oct;14(5):225-31

Division of Health Sciences and Technology, Harvard-Massachusetts Institute of Technology, Harvard Medical School, Boston, MA 02115, USA.

View Article and Find Full Text PDF
November 2005

In vivo testing of an infection-resistant annuloplasty ring.

J Surg Res 2006 Jan 8;130(1):140-5. Epub 2005 Sep 8.

Department of Surgery, Division of Vascular Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA.

View Article and Find Full Text PDF
January 2006

Local cytokine environments drive aneurysm formation in allografted aortas.

Trends Cardiovasc Med 2005 May;15(4):142-8

Cardiovascular Division, Department of Medicine, The Donald W. Reynolds Cardiovascular Clinical Research Center, Harvard Medical School, 77 Avenue Louis Pasteur, NRB7, Boston, MA 02115, USA.

View Article and Find Full Text PDF
May 2005

Interferon-gamma knockout fails to confer protection against obliteration in heterotopic murine tracheal allografts.

J Heart Lung Transplant 2005 Jun;24(6):658-64

Division of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School Boston, Massachusetts, USA.

View Article and Find Full Text PDF
June 2005

The link between IFN-gamma and allograft arteriopathy: is the answer NO?

J Clin Invest 2004 Sep;114(6):762-4

Center for Excellence in Vascular Biology, Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

View Article and Find Full Text PDF
September 2004

Th2-predominant inflammation and blockade of IFN-gamma signaling induce aneurysms in allografted aortas.

J Clin Invest 2004 Jul;114(2):300-8

The Donald W. Reynolds Cardiovascular Clinical Research Center, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article and Find Full Text PDF
July 2004

Wild-type but not interferon-gamma-deficient T cells induce graft arterial disease in the absence of B cells.

Cardiovasc Res 2004 Aug;63(2):347-56

Leducq Center for Cardiovascular Research, Cardiovascular Division, Department of Medicine, USA.

View Article and Find Full Text PDF
August 2004

Allograft arteriopathy: pathogenesis update.

Cardiovasc Pathol 2004 Jan-Feb;13(1):33-40

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, 77 Avenue Louis Pasteur/NRB 730D, Boston, MA 02115, USA.

View Article and Find Full Text PDF
November 2004

Direct anti-inflammatory mechanisms contribute to attenuation of experimental allograft arteriosclerosis by statins.

Circulation 2003 Oct 29;108(17):2113-20. Epub 2003 Sep 29.

The Donald W. Reynolds Cardiovascular Clinical Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02115, USA.

View Article and Find Full Text PDF
October 2003

Tumor necrosis factor receptor -1 and -2 double deficiency reduces graft arterial disease in murine cardiac allografts.

Am J Transplant 2003 Aug;3(8):968-76

Leducq Center for Cardiovascular Research, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article and Find Full Text PDF
August 2003

Allograft rejection in a new allospecific CD4+ TCR transgenic mouse.

Am J Transplant 2003 Apr;3(4):381-9

Renal Division, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article and Find Full Text PDF
April 2003

Stem cell origins of intimal cells in graft arterial disease.

Curr Atheroscler Rep 2003 May;5(3):230-7

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, EBRC 515, Boston, MA 02115, USA.

View Article and Find Full Text PDF
May 2003

Influence of insulin therapy on burn wound healing in rats.

J Surg Res 2003 Feb;109(2):92-100

Shriners Burns Hospital, Surgical Services and the Center for Engineering in Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02114, USA.

View Article and Find Full Text PDF
February 2003

Interferon gamma modulates trauma-induced muscle wasting and immune dysfunction.

Ann Surg 2002 Nov;236(5):649-57

Center for Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School and Shriners Hospital for Children, Boston, Massachusetts 20115, USA.

View Article and Find Full Text PDF
November 2002

CD8 T cells are sufficient to mediate allorecognition and allograft rejection.

Cell Immunol 2002 Mar-Apr;216(1-2):6-14

Division of Pediatrics, Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA.

View Article and Find Full Text PDF
January 2003

Antiproteolytic action of insulin in burn-injured rats.

J Surg Res 2002 Jun;105(2):234-42

Shriners Burns Hospital, Surgical Services and Center for Engineering in Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA.

View Article and Find Full Text PDF
June 2002

Antigen binding to GM1 ganglioside results in delayed presentation: minimal effects of GM1 on presentation of antigens internalized via other pathways.

Immunology 2002 May;106(1):60-70

Department of Pathology and Microbiology, School of Medical Sciences, University of Bristol, Bristol, UK.

View Article and Find Full Text PDF
May 2002

Cold ischemia induces isograft arteriopathy, but does not augment allograft arteriopathy in non-immunosuppressed hosts.

Am J Pathol 2002 Mar;160(3):1077-87

Vascular Medicine and Atherosclerosis Unit, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article and Find Full Text PDF
March 2002