Publications by authors named "Richard N Kolesnick"

20Publications

Sphingolipid abnormalities in cancer multidrug resistance: Chicken or egg?

Cell Signal 2017 10 4;38:134-145. Epub 2017 Jul 4.

Laboratory of Signal Transduction, Sloan Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, United States.

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October 2017

Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis.

Biochim Biophys Acta 2015 Nov 4;1851(11):1482-9. Epub 2015 Aug 4.

Department of Medicine, University of British Columbia, Vancouver, Canada. Electronic address:

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November 2015

Axitinib sensitization of high Single Dose Radiotherapy.

Radiother Oncol 2014 Apr 29;111(1):88-93. Epub 2014 Apr 29.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, USA.

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April 2014

It takes a CAD to kill a tumor cell with a LMP.

Cancer Cell 2013 Sep;24(3):279-81

Department of Molecular Biology, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.

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September 2013

Alpha particles induce apoptosis through the sphingomyelin pathway.

Radiat Res 2011 Oct 1;176(4):434-46. Epub 2011 Jun 1.

a  Memorial Sloan-Kettering Cancer Center, Department of Chemistry and Molecular Pharmacology, New York, New York 10065.

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October 2011

Kinetic characterization of mammalian ceramide synthases: determination of K(m) values towards sphinganine.

FEBS Lett 2007 Nov 23;581(27):5289-94. Epub 2007 Oct 23.

Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel.

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November 2007

Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrations.

Mitochondrion 2006 Jun 29;6(3):118-25. Epub 2006 Mar 29.

Department of Biology, University of Maryland, College Park, MD 20742, USA.

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June 2006

A central role for ceramide in the age-related acceleration of apoptosis in the female germline.

FASEB J 2005 May 23;19(7):860-2. Epub 2005 Feb 23.

Vincent Center for Reproductive Biology, Vincent Obstetrics and Gynecology Service, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.

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May 2005

Ceramide synthesis and metabolism as a target for cancer therapy.

Cancer Lett 2004 Apr;206(2):169-80

Division of Hematology-Oncology MS 57, Children's Hospital of Los Angeles, The University of Southern California Keck School of Medicine, 4650 Sunset Blvd., Los Angeles, CA 90054-0700, USA.

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April 2004

Sphingomyelinase activity causes transbilayer lipid translocation in model and cell membranes.

J Biol Chem 2003 Sep 10;278(39):37169-74. Epub 2003 Jul 10.

Unidad de Biofísica (Centro Mixto CSIC-UPV/EHU), Universidad del País Vasco, 48080 Bilbao, Spain.

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September 2003

Ceramide and sphingosine 1-phosphate in anti-cancer therapies.

Cancer Treat Res 2003 ;115:345-54

Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA.

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July 2003

Sphingolipids, apoptosis, cancer treatments and the ovary: investigating a crime against female fertility.

Biochim Biophys Acta 2002 Dec;1585(2-3):135-8

Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital/Harvard Medical School, 55 Fruit Street, VBK137E-GYN, Boston, MA 02114-2696, USA.

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December 2002

Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene diepoxide exposure of female mice in vivo.

Endocrinology 2003 Jan;144(1):69-74

Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts 02114, USA.

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January 2003

Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins.

J Biol Chem 2002 Jul 10;277(30):26796-803. Epub 2002 May 10.

Department of Biology, University of Maryland, College Park, MD 20742, USA.

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July 2002