Richard Mott

Richard Mott

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Richard Mott

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A 3,000-year-old Egyptian emmer wheat genome reveals dispersal and domestication history.

Nat Plants 2019 Nov 4;5(11):1120-1128. Epub 2019 Nov 4.

Genetics Institute, Research Department of Genetics, Evolution and Environment, University College London, London, UK.

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http://dx.doi.org/10.1038/s41477-019-0534-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858886PMC
November 2019

ADDO: a comprehensive toolkit to detect, classify and visualise additive and non-additive Quantitative Trait Loci.

Bioinformatics 2019 Nov 25. Epub 2019 Nov 25.

State Key Laboratory for Pig Genetic Improvement and Production Technology, Jiangxi Agricultural University, Nanchang, P. R. China.

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http://dx.doi.org/10.1093/bioinformatics/btz786DOI Listing
November 2019

Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance.

Dis Model Mech 2019 07 15;12(7). Epub 2019 Jul 15.

The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, United Kingdom

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http://dx.doi.org/10.1242/dmm.038539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679378PMC
July 2019

Genome-wide sexually antagonistic variants reveal long-standing constraints on sexual dimorphism in fruit flies.

PLoS Biol 2019 04 25;17(4):e3000244. Epub 2019 Apr 25.

Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.3000244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504117PMC
April 2019

Mapping novel genetic loci associated with female liver weight variations using Collaborative Cross mice.

Animal Model Exp Med 2018 Sep 24;1(3):212-220. Epub 2018 Oct 24.

Sackler Faculty of Medicine Tel-Aviv University Tel-Aviv Israel.

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http://dx.doi.org/10.1002/ame2.12036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388055PMC
September 2018

Weighted Burden Analysis of Exome-Sequenced Case-Control Sample Implicates Synaptic Genes in Schizophrenia Aetiology.

Behav Genet 2018 05 21;48(3):198-208. Epub 2018 Mar 21.

UCL Genetics Institute, University College London, Darwin Building, Gower Street, London, WC1E 6BT, UK.

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http://dx.doi.org/10.1007/s10519-018-9893-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934462PMC
May 2018

Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice.

BMC Genomics 2018 Apr 27;19(1):303. Epub 2018 Apr 27.

Institut Pasteur, Department of Development & Stem Cell Biology, Mouse Functional Genetics, F-75015, Paris, France.

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http://dx.doi.org/10.1186/s12864-018-4667-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923191PMC
April 2018

Heterogeneous Stock Populations for Analysis of Complex Traits.

Methods Mol Biol 2017 ;1488:31-44

UCL Genetics Institute, University College London, Gower St., London, WC1E 6BT, UK.

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http://dx.doi.org/10.1007/978-1-4939-6427-7_2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869698PMC
January 2018

Unstable Inheritance of 45S rRNA Genes in .

G3 (Bethesda) 2017 04 3;7(4):1201-1209. Epub 2017 Apr 3.

Gregor Mendel Institute, Austrian Academy of Sciences, Vienna Biocenter (VBC), 1030, Austria

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http://dx.doi.org/10.1534/g3.117.040204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386868PMC
April 2017

Glucose tolerance female-specific QTL mapped in collaborative cross mice.

Mamm Genome 2017 02 2;28(1-2):20-30. Epub 2016 Nov 2.

Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, 69978, Tel Aviv, Israel.

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http://dx.doi.org/10.1007/s00335-016-9667-2DOI Listing
February 2017

Mapping liver fat female-dependent quantitative trait loci in collaborative cross mice.

Mamm Genome 2016 12 15;27(11-12):565-573. Epub 2016 Jul 15.

Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, 69978, Tel Aviv, Israel.

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http://dx.doi.org/10.1007/s00335-016-9658-3DOI Listing
December 2016

Determining Phenological Patterns Associated with the Onset of Senescence in a Wheat MAGIC Mapping Population.

Front Plant Sci 2016 24;7:1540. Epub 2016 Oct 24.

The John Bingham Laboratory, National Institute of Agricultural Botany Cambridge, UK.

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http://dx.doi.org/10.3389/fpls.2016.01540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075575PMC
October 2016

The Amount of Mitochondrial DNA in Blood Reflects the Course of a Depressive Episode.

Biol Psychiatry 2016 09 30;80(6):e41-e42. Epub 2015 Dec 30.

Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2015.12.019DOI Listing
September 2016

Rapid genotype imputation from sequence without reference panels.

Nat Genet 2016 08 4;48(8):965-969. Epub 2016 Jul 4.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966640PMC
August 2016

A multiple-phenotype imputation method for genetic studies.

Nat Genet 2016 Apr 22;48(4):466-72. Epub 2016 Feb 22.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817234PMC
April 2016

High-fat-diet induced development of increased fasting glucose levels and impaired response to intraperitoneal glucose challenge in the collaborative cross mouse genetic reference population.

BMC Genet 2016 Jan 5;17:10. Epub 2016 Jan 5.

Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Tel-Aviv, 69978, Israel.

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http://dx.doi.org/10.1186/s12863-015-0321-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700737PMC
January 2016

Genetic Control over mtDNA and Its Relationship to Major Depressive Disorder.

Curr Biol 2015 Dec 10;25(24):3170-7. Epub 2015 Dec 10.

Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, Oxfordshire OX3 7BN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.10.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691240PMC
December 2015

Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture.

BMC Genomics 2015 Nov 26;16:1013. Epub 2015 Nov 26.

Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1186/s12864-015-2213-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661944PMC
November 2015

Genetic differential calculus.

Authors:
Richard Mott

Nat Genet 2015 Sep;47(9):965-6

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3384DOI Listing
September 2015

Environmentally responsive genome-wide accumulation of de novo Arabidopsis thaliana mutations and epimutations.

Genome Res 2014 Nov 14;24(11):1821-9. Epub 2014 Oct 14.

Department of Plant Sciences, University of Oxford, Oxford OX1 3RB, United Kingdom;

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http://dx.doi.org/10.1101/gr.177659.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216923PMC
November 2014

Susceptibility to Klebsiella pneumonaie infection in collaborative cross mice is a complex trait controlled by at least three loci acting at different time points.

BMC Genomics 2014 Oct 6;15:865. Epub 2014 Oct 6.

Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1186/1471-2164-15-865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201739PMC
October 2014

Heritability and coefficient of genetic variation analyses of phenotypic traits provide strong basis for high-resolution QTL mapping in the Collaborative Cross mouse genetic reference population.

Mamm Genome 2014 Apr 21;25(3-4):109-19. Epub 2014 Jan 21.

Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, 69978, Tel Aviv, Israel,

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http://dx.doi.org/10.1007/s00335-014-9503-5DOI Listing
April 2014

Microarray-based ultra-high resolution discovery of genomic deletion mutations.

BMC Genomics 2014 Mar 22;15:224. Epub 2014 Mar 22.

Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK.

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http://dx.doi.org/10.1186/1471-2164-15-224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998191PMC
March 2014

The architecture of parent-of-origin effects in mice.

Cell 2014 Jan;156(1-2):332-42

Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1016/j.cell.2013.11.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898482PMC
January 2014

Dissecting quantitative traits in mice.

Annu Rev Genomics Hum Genet 2013 3;14:421-39. Epub 2013 Jul 3.

Wellcome Trust Center for Human Genetics, University of Oxford, Oxford OX3 7BN, United Kingdom; email: ,

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http://dx.doi.org/10.1146/annurev-genom-091212-153419DOI Listing
December 2013

[Genome sequencing and genetic mapping to dissect the genetic basis of complex traits].

Med Sci (Paris) 2013 Jun-Jul;29(6-7):671-4. Epub 2013 Jul 12.

Wellcome Trust Centre for Human Genetics, Oxford, UK.

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http://dx.doi.org/10.1051/medsci/2013296024DOI Listing
September 2013

Genotype is an important determinant factor of host susceptibility to periodontitis in the Collaborative Cross and inbred mouse populations.

BMC Genet 2013 Aug 9;14:68. Epub 2013 Aug 9.

Department of Prosthodontics, Faculty of Dental Medicine, Hadassah Medical Centers and The Hebrew University, Jerusalem, Israel.

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http://dx.doi.org/10.1186/1471-2156-14-68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751202PMC
August 2013

Robust and sensitive analysis of mouse knockout phenotypes.

PLoS One 2012 26;7(12):e52410. Epub 2012 Dec 26.

Mouse Informatics Group, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052410PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530558PMC
July 2013

Cofilin-1: a modulator of anxiety in mice.

PLoS Genet 2012 4;8(10):e1002970. Epub 2012 Oct 4.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464202PMC
March 2013

Status and access to the Collaborative Cross population.

Mamm Genome 2012 Oct 31;23(9-10):706-12. Epub 2012 Jul 31.

Department of Computer Science, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1007/s00335-012-9410-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463789PMC
October 2012

Mapping the genetic basis of ecologically and evolutionarily relevant traits in Arabidopsis thaliana.

Curr Opin Plant Biol 2012 Apr 6;15(2):212-7. Epub 2012 Mar 6.

University of Bath, Department of Biology and Biochemistry, Claverton Down, BA2 7AY, UK.

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http://dx.doi.org/10.1016/j.pbi.2012.02.002DOI Listing
April 2012

Engineering a non-native hydrogen production pathway into Escherichia coli via a cyanobacterial [NiFe] hydrogenase.

Metab Eng 2011 Jul 27;13(4):445-53. Epub 2011 Jan 27.

ChELSI Institute, Department of Chemical and Biological Engineering, University of Sheffield, Mappin Street, UK.

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http://dx.doi.org/10.1016/j.ymben.2011.01.004DOI Listing
July 2011

Genetic architecture of flowering-time variation in Arabidopsis thaliana.

Genetics 2011 Jun 15;188(2):421-33. Epub 2011 Mar 15.

Department of Molecular Biology, Max Planck Institute for Developmental Biology, Tübingen, Germany.

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http://dx.doi.org/10.1534/genetics.111.126607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122318PMC
June 2011

Enzymatic characterisation of USP7 deubiquitinating activity and inhibition.

Cell Biochem Biophys 2011 Jun;60(1-2):99-111

Oncology iMed, AstraZeneca, Mereside, Alderley Park, Macclesfield, Cheshire, SK10 4TG, United Kingdom.

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http://dx.doi.org/10.1007/s12013-011-9186-4DOI Listing
June 2011

GLIDERS--a web-based search engine for genome-wide linkage disequilibrium between HapMap SNPs.

BMC Bioinformatics 2009 Oct 31;10:367. Epub 2009 Oct 31.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1186/1471-2105-10-367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777181PMC
October 2009

Mapping in structured populations by resample model averaging.

Genetics 2009 Aug 27;182(4):1263-77. Epub 2009 May 27.

Wellcome Trust Centre for Human Genetics, Roosevelt Dr., Oxford OX3 7BN, United Kingdom.

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http://dx.doi.org/10.1534/genetics.109.100727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728864PMC
August 2009

The 1001 genomes project for Arabidopsis thaliana.

Genome Biol 2009 27;10(5):107. Epub 2009 May 27.

Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1186/gb-2009-10-5-107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718507PMC
August 2009

Applying mouse complex-trait resources to behavioural genetics.

Nature 2008 Dec;456(7223):724-7

Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/nature07630DOI Listing
December 2008

Genetic variants in major depression.

Novartis Found Symp 2008 ;289:23-32; discussion 33-42, 87-93

Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1002/9780470751251.ch3DOI Listing
August 2008

The Collaborative Cross, developing a resource for mammalian systems genetics: a status report of the Wellcome Trust cohort.

Mamm Genome 2008 Jun 3;19(6):379-81. Epub 2008 Jun 3.

Department of Human Microbiology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1007/s00335-008-9113-1DOI Listing
June 2008

Prospects for complex trait analysis in the mouse.

Mamm Genome 2008 May 21;19(5):306-8. Epub 2008 May 21.

Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 9JN, UK.

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http://dx.doi.org/10.1007/s00335-008-9110-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515547PMC
May 2008

A haplotype map for the laboratory mouse.

Authors:
Richard Mott

Nat Genet 2007 Sep;39(9):1054-6

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http://www.nature.com/doifinder/10.1038/ng0907-1054
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http://dx.doi.org/10.1038/ng0907-1054DOI Listing
September 2007

Can psychiatric approaches help to address global warming?

Authors:
Richard B Mott

MedGenMed 2007 Aug 10;9(3):33; author reply 33. Epub 2007 Aug 10.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100107PMC
August 2007

Management, presentation and interpretation of genome scans using GSCANDB.

Bioinformatics 2007 Jun 30;23(12):1545-9. Epub 2007 Mar 30.

Wellcome Trust Centre for Human Genetics, Oxford, UK.

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http://dx.doi.org/10.1093/bioinformatics/btm123DOI Listing
June 2007

Genetic and environmental effects on complex traits in mice.

Genetics 2006 Oct 3;174(2):959-84. Epub 2006 Aug 3.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1534/genetics.106.060004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1602068PMC
October 2006

Genome-wide genetic association of complex traits in heterogeneous stock mice.

Nat Genet 2006 Aug 9;38(8):879-87. Epub 2006 Jul 9.

Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/ng1840DOI Listing
August 2006