Richard Mithen

Richard Mithen

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Richard Mithen

Richard Mithen

Publications by authors named "Richard Mithen"

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Plant Bioactives and the Prevention of Prostate Cancer: Evidence from Human Studies.

Nutrients 2019 Sep 18;11(9). Epub 2019 Sep 18.

Quadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk NR4 7UQ, UK.

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http://dx.doi.org/10.3390/nu11092245DOI Listing
September 2019

Bioavailability of Glucoraphanin and Sulforaphane from High-Glucoraphanin Broccoli.

Mol Nutr Food Res 2018 09 8;62(18):e1700911. Epub 2018 Mar 8.

Food and Health Programme, Quadram Institute Bioscience, Norwich, United Kingdom.

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http://dx.doi.org/10.1002/mnfr.201700911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175108PMC
September 2018

Isothiocyanates for Human Health.

Mol Nutr Food Res 2018 09;62(18):e1870079

Moore Family Center for Whole Grain Foods, Nutrition and Preventive Health, College of Public Health and Human Sciences, Oregon State University, 211 Milam Hall, Corvallis, OR, 97331, USA.

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http://dx.doi.org/10.1002/mnfr.201870079DOI Listing
September 2018

The contribution of alliaceous and cruciferous vegetables to dietary sulphur intake.

Food Chem 2017 Nov 18;234:38-45. Epub 2017 Apr 18.

Food & Health Programme, Institute of Food Research, Norwich, UK. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2017.04.098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460521PMC
November 2017

Development of a LC-MS/MS Method for the Simultaneous Detection of Tricarboxylic Acid Cycle Intermediates in a Range of Biological Matrices.

J Anal Methods Chem 2017 18;2017:5391832. Epub 2017 Sep 18.

Food and Health Programme, Quadram Institute Bioscience, Norwich NR4 7UA, UK.

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http://dx.doi.org/10.1155/2017/5391832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624170PMC
September 2017

Accumulation of Palmitoylcarnitine and Its Effect on Pro-Inflammatory Pathways and Calcium Influx in Prostate Cancer.

Prostate 2016 10 12;76(14):1326-37. Epub 2016 Jul 12.

Food and Health Programme, Institute of Food Research, Norwich, United Kingdom.

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http://dx.doi.org/10.1002/pros.23222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996340PMC
October 2016

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.

Nat Genet 2015 Apr 2;47(4):367-372. Epub 2015 Mar 2.

Urological Research Laboratory, Cancer Research UK Cambridge Research Institute, Cambridge, UK.

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https://ueaeprints.uea.ac.uk/52532/2/39739_3_merged_14193243
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http://www.nature.com/doifinder/10.1038/ng.3221
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http://dx.doi.org/10.1038/ng.3221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380509PMC
April 2015

Effect of Sulforaphane on NOD2 via NF-κB: implications for Crohn's disease.

J Inflamm (Lond) 2015 20;12. Epub 2015 Jan 20.

Nutrigenomics New Zealand, University of Auckland, Private Bag 92019, Auckland, 1142 New Zealand.

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http://dx.doi.org/10.1186/s12950-015-0051-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335778PMC
February 2015

Suppression of LPS-induced transcription and cytokine secretion by the dietary isothiocyanate sulforaphane.

Mol Nutr Food Res 2014 Dec 27;58(12):2286-96. Epub 2014 Oct 27.

Food and Health Programme, Institute of Food Research, Norwich, UK.

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http://dx.doi.org/10.1002/mnfr.201400550DOI Listing
December 2014

Sulforaphane and prostate cancer interception.

Drug Discov Today 2014 Sep 19;19(9):1488-92. Epub 2014 Jul 19.

Food and Health Programme, Institute of Food Research, Norwich Research Park, Norwich, NR4 7UA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.07.007DOI Listing
September 2014

The metabolism of methylsulfinylalkyl- and methylthioalkyl-glucosinolates by a selection of human gut bacteria.

Mol Nutr Food Res 2014 Apr 30;58(4):875-83. Epub 2013 Oct 30.

Imperial College London, Division of Cell and Molecular Biology, London, UK.

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http://dx.doi.org/10.1002/mnfr.201300377DOI Listing
April 2014

Diurnal and light regulation of sulphur assimilation and glucosinolate biosynthesis in Arabidopsis.

J Exp Bot 2013 Feb 10;64(4):1039-48. Epub 2013 Jan 10.

Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, UK.

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http://dx.doi.org/10.1093/jxb/ers378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580815PMC
February 2013

Enhanced in vitro biological activity of synthetic 2-(2-pyridyl) ethyl isothiocyanate compared to natural 4-(methylsulfinyl) butyl isothiocyanate.

J Med Chem 2012 Nov 31;55(22):9682-92. Epub 2012 Oct 31.

Food & Health Programme, Institute of Food Research , Norwich Research Park, NR4 7UA United Kingdom.

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http://dx.doi.org/10.1021/jm300929vDOI Listing
November 2012

Plant science and human nutrition: challenges in assessing health-promoting properties of phytochemicals.

Plant Cell 2011 Jul 29;23(7):2483-97. Epub 2011 Jul 29.

Institute of Food Research, Norwich Research Park, Norwich NR47UA, United Kingdom.

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http://dx.doi.org/10.1105/tpc.111.087916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226206PMC
July 2011

Glucosinolate biochemical diversity and innovation in the Brassicales.

Phytochemistry 2010 Dec;71(17-18):2074-86

Institute of Food Research, Colney Lane, Norwich NR4 7UA, UK.

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http://dx.doi.org/10.1016/j.phytochem.2010.09.017DOI Listing
December 2010

Hypoxia-inducible factor-1 (HIF-1) pathway activation by quercetin in human lens epithelial cells.

Exp Eye Res 2009 Dec 1;89(6):995-1002. Epub 2009 Sep 1.

School of Pharmacy, University of East Anglia, Norwich NR4 7TJ, UK.

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http://dx.doi.org/10.1016/j.exer.2009.08.011DOI Listing
December 2009

Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21(waf1/cip1).

Nutr Cancer 2009 ;61(1):137-45

Phytochemicals and Health Programme, Institute of Food Research, Colney, England.

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http://dx.doi.org/10.1080/01635580802348641DOI Listing
April 2009

Polyamine metabolism and transforming growth factor-beta signaling are affected in Caco-2 cells by differentially cooked broccoli extracts.

J Nutr 2008 Oct;138(10):1840-5

Institute of Food Research, Norwich Research Park, Colney Lane, Norwich NR4 7UA, UK.

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http://dx.doi.org/10.1093/jn/138.10.1840DOI Listing
October 2008

Consuming broccoli does not induce genes associated with xenobiotic metabolism and cell cycle control in human gastric mucosa.

J Nutr 2007 Jul;137(7):1718-24

Phytochemicals and Health Programme, Institute of Food Research, Colney, Norwich NR4 7UA, UK.

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http://dx.doi.org/10.1093/jn/137.7.1718DOI Listing
July 2007

Effect of genotype on micronutrient absorption and metabolism: a review of iron, copper, iodine and selenium, and folates.

Authors:
Richard Mithen

Int J Vitam Nutr Res 2007 May;77(3):205-16

Institute of Food Research, Colney Lane, Norwich, NR4 7UA, UK.

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http://dx.doi.org/10.1024/0300-9831.77.3.205DOI Listing
May 2007

Quantitative measurement of sulforaphane, iberin and their mercapturic acid pathway metabolites in human plasma and urine using liquid chromatography-tandem electrospray ionisation mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2006 Dec 23;844(2):223-34. Epub 2006 Aug 23.

Centre for Analytical Bioscience, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK.

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http://dx.doi.org/10.1016/j.jchromb.2006.07.007DOI Listing
December 2006

Epithiospecifier protein from broccoli (Brassica oleracea L. ssp. italica) inhibits formation of the anticancer agent sulforaphane.

J Agric Food Chem 2006 Mar;54(6):2069-76

Department of Food Science and Human Nutrition, University of Illinois, 905 South Goodwin Avenue, Urbana, Illinois 61801, USA.

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http://pubs.acs.org/doi/abs/10.1021/jf0525277
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http://dx.doi.org/10.1021/jf0525277DOI Listing
March 2006

Expression of a Brassica isopropylmalate synthase gene in Arabidopsis perturbs both glucosinolate and amino acid metabolism.

Plant Mol Biol 2006 Mar;60(5):717-27

John Innes Centre, Colney Lane, Norwich NR4 7UH, UK.

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http://dx.doi.org/10.1007/s11103-005-5547-yDOI Listing
March 2006

Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli.

Am J Clin Nutr 2005 Dec;82(6):1283-91

Phytochemicals and Health Programme, Institute of Food Research, Norwich Research Park, Colney, Norwich, United Kingdom.

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http://dx.doi.org/10.1093/ajcn/82.6.1283DOI Listing
December 2005

Elevated CO(2) influences herbivory-induced defense responses of Arabidopsis thaliana.

Oecologia 2005 Sep 29;145(3):415-24. Epub 2005 Sep 29.

Department of Animal Biology, School of Integrative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 1801, USA.

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http://dx.doi.org/10.1007/s00442-005-0158-5DOI Listing
September 2005

Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane.

J Nutr 2005 Aug;135(8):1865-72

Nutrition Division, Institute of Food Research, Norwich, UK.

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http://dx.doi.org/10.1093/jn/135.8.1865DOI Listing
August 2005

Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells.

Biochem Pharmacol 2005 Jun 21;69(11):1543-52. Epub 2005 Apr 21.

Nutrition Division, Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, UK.

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http://dx.doi.org/10.1016/j.bcp.2005.03.015DOI Listing
June 2005

Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells.

J Agric Food Chem 2005 Mar;53(5):1417-21

Nutrition Division, Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, UK.

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http://dx.doi.org/10.1021/jf048153jDOI Listing
March 2005

Glucosinolate and amino acid biosynthesis in Arabidopsis.

Plant Physiol 2004 Jun 21;135(2):828-39. Epub 2004 May 21.

Department of Metabolic Biology, John Innes Centre, Norwich NR4 7UH, United Kingdom.

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http://www.plantphysiol.org/cgi/doi/10.1104/pp.104.039347
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http://dx.doi.org/10.1104/pp.104.039347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514118PMC
June 2004

Effects of Brassica vegetable juice on the induction of apoptosis and aberrant crypt foci in rat colonic mucosal crypts in vivo.

Carcinogenesis 2003 Mar;24(3):491-5

Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK.

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http://dx.doi.org/10.1093/carcin/24.3.491DOI Listing
March 2003

Growth and mortality of individual plants as a function of "available area".

Oecologia 1984 Apr;62(1):57-60

Department of Biology, Swarthmore College Swarthmore, 19081, PA, USA.

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http://dx.doi.org/10.1007/BF00377373DOI Listing
April 1984