Richard M Weinshilboum

Richard M Weinshilboum

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Richard M Weinshilboum

Richard M Weinshilboum

Publications by authors named "Richard M Weinshilboum"

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Dual roles for the TSPYL family in mediating serotonin transport and the metabolism of selective serotonin reuptake inhibitors in MDD patients.

Clin Pharmacol Ther 2019 Oct 19. Epub 2019 Oct 19.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cpt.1692
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http://dx.doi.org/10.1002/cpt.1692DOI Listing
October 2019

Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand-Dependent Gene Expression.

Drug Metab Dispos 2019 Sep 10;47(9):983-994. Epub 2019 Jul 10.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (D.R.N., D.L., H.L., L.W., R.M.W.), Epigenomics Program, Center for Individualized Medicine (J.-H.L., T.O.), Division of Experimental Pathology and Laboratory Medicine, Department of Laboratory Medicine and Pathology (J.-H.L.), Division of Biomedical Statistics and Informatics (Z.Y.), Department of Physiology and Biomedical Engineering (T.O.), and Division of Gastroenterology and Hepatology, Department of Medicine (T.O.), Mayo Clinic, Rochester, Minnesota

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http://dx.doi.org/10.1124/dmd.119.087312DOI Listing
September 2019

Catechol O-Methyltransferase Pharmacogenomics: Challenges and Opportunities.

Clin Pharmacol Ther 2019 Aug 13;106(2):281-283. Epub 2019 May 13.

1Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/cpt.1452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663608PMC
August 2019

4-Hydroxytamoxifen enhances sensitivity of estrogen receptor α-positive breast cancer to docetaxel in an estrogen and ZNF423 SNP-dependent fashion.

Breast Cancer Res Treat 2019 Jun 1;175(3):567-578. Epub 2019 Apr 1.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/s10549-019-05194-zDOI Listing
June 2019

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall.

Oncotarget 2019 Jun 11;10(39):3924-3930. Epub 2019 Jun 11.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.18632/oncotarget.27001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570466PMC
June 2019

Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in and .

Drug Metab Dispos 2019 04 11;47(4):425-435. Epub 2019 Feb 11.

Departments of Molecular Pharmacology and Experimental Therapeutics (S.D., I.M., M.-F.H., L.W., R.M.W., J.M.R.) and Health Sciences Research (N.B.L., S.J.B.), Personalized Genomics Laboratory, Department of Laboratory Medicine and Pathology (A.M.M., J.L.B.), and Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Graduate School of Biomedical Sciences (D.R.N.), Mayo Clinic, Rochester, Minnesota; and Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas (S.E.S.)

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http://dx.doi.org/10.1124/dmd.118.084269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423619PMC
April 2019

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1.

Breast Cancer Res 2019 04 3;21(1):47. Epub 2019 Apr 3.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1186/s13058-019-1130-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448248PMC
April 2019

The Role of the Aryl Hydrocarbon Receptor (AHR) in Immune and Inflammatory Diseases.

Int J Mol Sci 2018 Dec 3;19(12). Epub 2018 Dec 3.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55902, USA.

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http://www.mdpi.com/1422-0067/19/12/3851
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http://dx.doi.org/10.3390/ijms19123851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321643PMC
December 2018

Single Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 Induction.

Drug Metab Dispos 2018 09 6;46(9):1372-1381. Epub 2018 Jul 6.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (D.L., S.Q., B.R., L.W., R.M.W.) and Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.K.), Mayo Clinic, Rochester, Minnesota

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http://dx.doi.org/10.1124/dmd.118.082164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090174PMC
September 2018

SLCO1B1 genetic variation and hormone therapy in menopausal women.

Menopause 2018 08;25(8):877-882

Departments of Surgery and Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/GME.0000000000001109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092108PMC
August 2018

BRCA1/2 Mutations and Bevacizumab in the Neoadjuvant Treatment of Breast Cancer: Response and Prognosis Results in Patients With Triple-Negative Breast Cancer From the GeparQuinto Study.

J Clin Oncol 2018 08 23;36(22):2281-2287. Epub 2018 May 23.

Peter A. Fasching and Matthias Rübner, Erlangen University Hospital, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen; Sibylle Loibl, Valentina Nekljudova, Karsten E. Weber, and Gunter von Minckwitz, German Breast Group Forschungs, Neu-Isenburg; Christian Schem, University Medical Center Schleswig-Holstein, Kiel; Hans Tesch, Centrum für Hämatologie und Onkologie Bethanien, Frankfurt; Michael Untch, Helios-Klinikum, Berlin-Buch; Jörn Hilfrich, Eilenriede-Klinik, Hannover; Mahdi Rezai, Luisenkrankenhaus; Tanja Fehm, Düsseldorf University Hospital, Heinrich-Heine University of Düsseldorf, Düsseldorf; Bernd Gerber, University of Rostock, Rostock; Serban Dan Costa, Magdeburg University Hospital, Magdeburg; Jens-Uwe Blohmer and Cornelia Liedtke, Charité University Hospital Campus Charité-Mitte, Berlin; Jens Huober, University of Ulm; Brigitte Rack, University Hospital Ulm, Ulm; Volkmar Müller, Hamburg University Hospital, Hamburg, Germany; Chunling Hu, Steven N. Hart, Hermela Shimelis, Raymond Moore, James N. Ingle, and Fergus J. Couch, Mayo Clinic; and Richard M. Weinshilboum and Liewei Wang, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN.

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http://ascopubs.org/doi/10.1200/JCO.2017.77.2285
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http://dx.doi.org/10.1200/JCO.2017.77.2285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067803PMC
August 2018

, a Novel Transcription Factor and a Coregulator of Nuclear Factor B p65: Single Nucleotide Polymorphism and Estrogen Dependence.

J Pharmacol Exp Ther 2018 06 28;365(3):700-710. Epub 2018 Mar 28.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (M.H., E.L.d.R., C.Z., L.W., H.L., R.M.W.), and Division of Medical Oncology, Department of Oncology (J.N.I.), Mayo Clinic, Rochester, Minnesota; Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, Massachusetts (P.E.G.); Canadian Cancer Trials Group, Kingston, Ontario, Canada (L.E.S.); and RIKEN Center for Integrative Medical Science, Yokohama, Japan (M.K.)

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http://dx.doi.org/10.1124/jpet.118.247718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954488PMC
June 2018

Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression.

Biochem Pharmacol 2018 06 3;152:279-292. Epub 2018 Apr 3.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.03.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960634PMC
June 2018

Pharmacogenomics: Precision Medicine and Drug Response.

Mayo Clin Proc 2017 11 1;92(11):1711-1722. Epub 2017 Nov 1.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2017.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682947PMC
November 2017

Single-Nucleotide Polymorphisms and Estrogen-Mediated Toll-Like Receptor-MYD88-Dependent Nuclear Factor-B Activation: Single-Nucleotide Polymorphism- and Selective Estrogen Receptor Modulator-Dependent Modification of Inflammation and Immune Response.

Mol Pharmacol 2017 08 14;92(2):175-184. Epub 2017 Jun 14.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (M.-F.H., L.W., R.M.W.), Division of Medical Oncology, Department of Oncology (J.N.I.), and Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.K.), Mayo Clinic, Rochester, Minnesota; Department of Emergency Medicine, Vanderbilt Medical Center, Nashville, Tennessee (T.B.); Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, Massachusetts (P.E.G.); NCIC Clinical Trials Group, Kingston, Ontario Canada (L.E.S.); and RIKEN Center for Integrative Medical Science, Tsurumi-ku, Yokohama, Japan (T.M., M.K.)

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http://molpharm.aspetjournals.org/lookup/doi/10.1124/mol.117
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http://dx.doi.org/10.1124/mol.117.108340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508195PMC
August 2017

Immune Mediator Pharmacogenomics: SNPs and Estrogen-Dependent Regulation of Inflammation.

J Nat Sci 2017 Aug;3(8)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578609PMC
August 2017

Genome-wide association studies of drug response and toxicity: an opportunity for genome medicine.

Nat Rev Drug Discov 2017 Jan 25;16(1). Epub 2016 Nov 25.

RIKEN Center for Integrative Medical Science, Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1038/nrd.2016.234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443656PMC
January 2017

Using EHR-Linked Biobank Data to Study Metformin Pharmacogenomics.

Stud Health Technol Inform 2015 ;210:914-8

Mayo Clinic, Department of Health of Sciences Research.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051541PMC
November 2016

Influence of SULT1A1 genetic variation on age at menopause, estrogen levels, and response to hormone therapy in recently postmenopausal white women.

Menopause 2016 08;23(8):863-9

1Department of Laboratory Medicine and Pathology 2Division of Biomedical Statistics and Informatics 3Department of Molecular Pharmacology and Experimental Therapeutics 4Departments of Surgery and Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/GME.0000000000000648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961269PMC
August 2016

Combined Effects of Acamprosate and Escitalopram on Ethanol Consumption in Mice.

Alcohol Clin Exp Res 2016 07 17;40(7):1531-9. Epub 2016 May 17.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, College of Medicine, Rochester, Minnesota.

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http://dx.doi.org/10.1111/acer.13099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020905PMC
July 2016

Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation.

Mol Endocrinol 2016 Mar 11;30(3):382-98. Epub 2016 Feb 11.

Division of Clinical Pharmacology (M.-F.H., M.L., L.W., R.M.W.), Department of Molecular Pharmacology and Experimental Therapeutics, Division of Rheumatology (M.-F.H., T.B.), Department of Medicine, Division of Biomedical Statistics and Informatics (K.R.K.), Department of Health Sciences Research, and Division of Medical Oncology (M.P.G., J.N.I.), Department of Oncology, Mayo Clinic, Rochester, Minnesota 55905; Division of Hematology/Oncology (P.E.G.), Department of Medicine, Massachusetts General Hospital Cancer Center, Harvard University, Boston, Massachusetts 02114; National Cancer Institute of Canada Clinical Trials Group (L.E.S.), Kingston, Ontario, Canada K7L 3N6; and RIKEN Center for Integrative Medical Science (M.K.), Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1210/me.2015-1267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771694PMC
March 2016

Accuracy of Electronic Medical Record Medication Reconciliation in Emergency Department Patients.

J Emerg Med 2015 Jul 19;49(1):78-84. Epub 2015 Mar 19.

Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado; Rocky Mountain Poison & Drug Center, Denver, Colorado.

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http://dx.doi.org/10.1016/j.jemermed.2014.12.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476907PMC
July 2015

Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites.

Circ Cardiovasc Genet 2015 Feb 1;8(1):141-9. Epub 2014 Dec 1.

From the Division of Cardiovascular Diseases, Department of Internal Medicine (N.L.P., T.M.O., R.J.R., M.M.R., J.C.B.), Department of Biomedical Statistics and Informatics (N.T., C.G.S, G.D.J., N.P.), and Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (N.L.P., R.M.W.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1161/CIRCGENETICS.114.000624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387792PMC
February 2015

Electrophysiological Neuroimaging using sLORETA Comparing 22 Age Matched Male and Female Schizophrenia Patients.

Hosp Chron 2015;10(2):91-98

Department of Molecular Pharmacology and Experimental Therapeutics, Division of Clinical Pharmacology, Gonda 19, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662405PMC
January 2015

Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.

Mol Endocrinol 2014 Oct 22;28(10):1740-51. Epub 2014 Aug 22.

Division of Clinical Pharmacology (M.L., L.W., R.M.W.), Department of Molecular Pharmacology and Experimental Therapeutics; Departments of Oncology (J.N.I.) and Health Sciences Research (A.B., G.D.J., E.E.C., D.J.S.); and Division of Endocrinology (S.K.), Mayo Clinic, Rochester, Minnesota 55905; Massachusetts General Hospital (P.E.G.), Harvard University, Boston, Massachusetts 02114; Rikagaku Kenkyūsho Center for Integrative Medical Science (M.K., Y.F.), Yokohama, Japan 230-0045; School of Medicine (Y.N.), Chicago University, Chicago, Illinois 60637; National Cancer Institute of Canada Clinical Trials Group (J.-A.W.C., L.E.S.), Kingston, Ontario, Canada K7L 3N6; and Division of Oncology (M.J.E.), Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110.

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http://dx.doi.org/10.1210/me.2014-1147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179631PMC
October 2014

The effect of CYP2D6 drug-drug interactions on hydrocodone effectiveness.

Acad Emerg Med 2014 Aug 24;21(8):879-85. Epub 2014 Aug 24.

Department of Emergency Medicine, University of Colorado, Aurora, CO; Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA; Rocky Mountain Poison & Drug Center, Denver, CO.

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http://dx.doi.org/10.1111/acem.12431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150819PMC
August 2014

TPMT genetic variants are associated with increased rejection with azathioprine use in heart transplantation.

Pharmacogenet Genomics 2013 Dec;23(12):658-65

Department of aInternal Medicine bBiostatistics cMedicine, Division of Cardiovascular Diseases dDepartment of Molecular Pharmacology and Experimental Therapeutics, Division of Clinical Pharmacology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894785PMC
December 2013

Two-phase designs to follow-up genome-wide association signals with DNA resequencing studies.

Genet Epidemiol 2013 Apr 24;37(3):229-38. Epub 2013 Jan 24.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/gepi.21708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740575PMC
April 2013

Pharmacogenomics and patient care: one size does not fit all.

Sci Transl Med 2012 Sep;4(153):153ps18

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1126/scitranslmed.3003471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963516PMC
September 2012

PharmGKB summary: very important pharmacogene information for GSTT1.

Pharmacogenet Genomics 2012 Aug;22(8):646-51

Department of Genetics, Stanford University Medical Center, Stanford, California, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283527c02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395771PMC
August 2012

An interview with Pharmacogenomics for the breast cancer special focus issue.

Pharmacogenomics 2012 Apr;13(6):655-8

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http://dx.doi.org/10.2217/pgs.12.33DOI Listing
April 2012

Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization.

J Neurochem 2012 Mar 6;120(6):881-90. Epub 2012 Feb 6.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2012.07646.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296836PMC
March 2012

Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression.

Breast Cancer Res 2012 Mar 9;14(2):R41. Epub 2012 Mar 9.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1186/bcr3137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446375PMC
March 2012

Using the gene ontology to scan multilevel gene sets for associations in genome wide association studies.

Genet Epidemiol 2012 Jan 7;36(1):3-16. Epub 2011 Dec 7.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://doi.wiley.com/10.1002/gepi.20632
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http://dx.doi.org/10.1002/gepi.20632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310255PMC
January 2012

Methionine adenosyltransferase 2A/2B and methylation: gene sequence variation and functional genomics.

Drug Metab Dispos 2011 Nov 3;39(11):2135-47. Epub 2011 Aug 3.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1124/dmd.111.040857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198898PMC
November 2011

Gene set analysis of purine and pyrimidine antimetabolites cancer therapies.

Pharmacogenet Genomics 2011 Nov;21(11):701-12

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32834a48a9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192305PMC
November 2011

Mycophenolic acid response biomarkers: a cell line model system-based genome-wide screen.

Int Immunopharmacol 2011 Aug 23;11(8):1057-64. Epub 2011 Mar 23.

Division of Clinical Pharmacology, Department of Pharmacology and Experimental Therapeutics, Rochester, MN 55905, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S156757691100119
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http://dx.doi.org/10.1016/j.intimp.2011.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138818PMC
August 2011

Genomics and drug response.

N Engl J Med 2011 Mar;364(12):1144-53

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Medical School, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1056/NEJMra1010600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184612PMC
March 2011

Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation.

Mol Genet Metab 2011 Feb 21;102(2):126-33. Epub 2010 Oct 21.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.ymgme.2010.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053054PMC
February 2011

CYP2C19 variation and citalopram response.

Pharmacogenet Genomics 2011 Jan;21(1):1-9

Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090085PMC
http://dx.doi.org/10.1097/fpc.0b013e328340bc5aDOI Listing
January 2011

Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity.

Drug Metab Dispos 2010 Dec 20;38(12):2329-38. Epub 2010 Sep 20.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1124/dmd.110.035220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993460PMC
December 2010

CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system.

Leuk Lymphoma 2010 Jul;51(7):1315-25

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.3109/10428194.2010.483299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892000PMC
July 2010

Coprescription of tamoxifen and medications that inhibit CYP2D6.

J Clin Oncol 2010 Jun 3;28(16):2768-76. Epub 2010 May 3.

Department of Oncology, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1200/JCO.2009.23.8931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881853PMC
June 2010

Copy number variation and cytidine analogue cytotoxicity: a genome-wide association approach.

BMC Genomics 2010 Jun 4;11:357. Epub 2010 Jun 4.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1186/1471-2164-11-357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894803PMC
June 2010

Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.

Cancer Epidemiol Biomarkers Prev 2010 Mar 3;19(3):811-21. Epub 2010 Mar 3.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837367PMC
March 2010