Richard Leigh

Richard Leigh

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Richard Leigh

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Post-Stroke Blood-Brain Barrier Disruption and Poor Functional Outcome in Patients Receiving Thrombolytic Therapy.

Cerebrovasc Dis 2019 Apr 10:1-8. Epub 2019 Apr 10.

National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA,

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http://dx.doi.org/10.1159/000499666DOI Listing
April 2019

The Efficacy of IV Tissue Plasminogen Activator for Restoring Cerebral Blood Flow in the Hours Immediately after Administration in Patients with Acute Stroke.

J Neuroimaging 2019 Mar 3;29(2):206-210. Epub 2018 Dec 3.

National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1111/jon.12587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403008PMC
March 2019

Rhinovirus and Bacteria Synergistically Induce IL-17C Release from Human Airway Epithelial Cells To Promote Neutrophil Recruitment.

J Immunol 2019 Jan 30;202(1):160-170. Epub 2018 Nov 30.

Department of Physiology and Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta T2N 4Z6, Canada; and

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http://dx.doi.org/10.4049/jimmunol.1800547DOI Listing
January 2019

Sustained Opening of the Blood-Brain Barrier with Progressive Accumulation of White Matter Hyperintensities Following Ischemic Stroke.

Brain Sci 2019 Jan 21;9(1). Epub 2019 Jan 21.

Neuro Vascular Brain Imaging Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.3390/brainsci9010016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356213PMC
January 2019

Glucocorticoid-driven transcriptomes in human airway epithelial cells: commonalities, differences and functional insight from cell lines and primary cells.

BMC Med Genomics 2019 Jan 31;12(1):29. Epub 2019 Jan 31.

Airways Inflammation Research Group, Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1186/s12920-018-0467-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357449PMC
January 2019

Recurrent thrombolysis of a stuttering lacunar infarction captured on serial MRIs.

eNeurologicalSci 2018 Dec 30;13:14-17. Epub 2018 Oct 30.

Section on Stroke Diagnostics and Therapeutics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.

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http://dx.doi.org/10.1016/j.ensci.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224319PMC
December 2018

Imaging the physiological evolution of the ischemic penumbra in acute ischemic stroke.

J Cereb Blood Flow Metab 2018 Sep 27;38(9):1500-1516. Epub 2017 Mar 27.

3 Department of Radiology, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/0271678X17700913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125975PMC
September 2018

Co-occurrence of Asthma and the Inflammatory Bowel Diseases: A Systematic Review and Meta-analysis.

Clin Transl Gastroenterol 2018 09 24;9(9):188. Epub 2018 Sep 24.

Children's Hospital of Eastern Ontario (CHEO) Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology & Nutrition, Children's Hospital of Eastern Ontario, Ottawa, Canada.

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http://dx.doi.org/10.1038/s41424-018-0054-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155154PMC
September 2018

Sex differences in outcomes after discharge from Alberta emergency departments for asthma: A large population-based study.

J Asthma 2018 Aug 16;55(8):817-825. Epub 2017 Oct 16.

g Department of Emergency Medicine , University of Alberta, University of Alberta Hospital , Edmonton , Alberta Canada.

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https://www.tandfonline.com/doi/full/10.1080/02770903.2017.1
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http://dx.doi.org/10.1080/02770903.2017.1373805DOI Listing
August 2018

Early Change in Stroke Size Performs Best in Predicting Response to Therapy.

Cerebrovasc Dis 2017 7;44(3-4):141-149. Epub 2017 Jul 7.

Neuro Vascular Brain Imaging Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1159/000477945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629107PMC
June 2018

Effectiveness of a standardized electronic admission order set for acute exacerbation of chronic obstructive pulmonary disease.

BMC Pulm Med 2018 May 30;18(1):93. Epub 2018 May 30.

Division of Pulmonary Medicine, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1186/s12890-018-0657-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975274PMC
May 2018

Blood-ocular barrier disruption in patients with acute stroke.

Neurology 2018 Mar 7;90(11):e915-e923. Epub 2018 Feb 7.

From the National Institute of Neurological Disorders and Stroke (E.H., A.N.S., M.L., L.L.L., R.L.), NIH, Bethesda, MD; and Department of Neurology (R.J.L.), Case Western Reserve University, Cleveland, OH.

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http://dx.doi.org/10.1212/WNL.0000000000005123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858944PMC
March 2018

White Matter Hyperintensity-Associated Blood-Brain Barrier Disruption and Vascular Risk Factors.

J Stroke Cerebrovasc Dis 2018 Feb 31;27(2):466-471. Epub 2017 Oct 31.

Neuro Vascular Brain Imaging Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.09.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808404PMC
February 2018

An MRI Hyperintense Acute Reperfusion Marker Is Related to Elevated Peripheral Monocyte Count in Acute Ischemic Stroke.

J Neuroimaging 2018 Jan 19;28(1):57-60. Epub 2017 Jul 19.

Section on Stroke Diagnostics and Therapeutics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1111/jon.12462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760433PMC
January 2018

Blood-brain barrier leakage increases with small vessel disease in acute ischemic stroke.

Neurology 2017 Nov 25;89(21):2143-2150. Epub 2017 Oct 25.

From the NEUROFARBA Department (F.A., D.I.), University of Florence, Italy; National Institute of Neurological Disorders and Stroke (R.L., M.L.), NIH, Bethesda, MD; Institute of Cardiovascular and Medical Sciences (F.A.), Queen Elizabeth University Hospital, Glasgow, UK; Department of Neurology (S.J.W.), Dell Medical School, University of Texas at Austin; and Institute of Cardiovascular & Medical Sciences (K.R.L.), University of Glasgow, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696647PMC
November 2017

Human β-defensin-2 production upon viral and bacterial co-infection is attenuated in COPD.

PLoS One 2017 10;12(5):e0175963. Epub 2017 May 10.

Department of Medicine, Snyder Institute for Chronic Diseases, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0175963PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425185PMC
September 2017

Perfusion Deficits and Association with Clinical Outcome in Patients with Anterior Choroidal Artery Stroke.

J Stroke Cerebrovasc Dis 2017 Aug 27;26(8):1755-1759. Epub 2017 Apr 27.

Stroke Diagnostics and Therapeutics Section, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, Maryland.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515365PMC
August 2017

Recovery of orthographic processing after stroke: A longitudinal fMRI study.

Cortex 2017 07 8;92:103-118. Epub 2017 Apr 8.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA; Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA; Cognitive Science, Johns Hopkins University, Baltimore, MD, 21218, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cortex.2017.03.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489136PMC
July 2017

Human Rhinovirus Infection of Epithelial Cells Modulates Airway Smooth Muscle Migration.

Am J Respir Cell Mol Biol 2017 06;56(6):796-803

1 Department of Physiology and Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1165/rcmb.2016-0252OCDOI Listing
June 2017

Rhinovirus-bacteria coexposure synergistically induces CCL20 production from human bronchial epithelial cells.

Am J Physiol Lung Cell Mol Physiol 2017 05 10;312(5):L731-L740. Epub 2017 Mar 10.

Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; and

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http://dx.doi.org/10.1152/ajplung.00362.2016DOI Listing
May 2017

A systematic review of the effectiveness of discharge care bundles for patients with COPD.

Thorax 2017 01 9;72(1):31-39. Epub 2016 Sep 9.

Alberta Health Services, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1136/thoraxjnl-2016-208820DOI Listing
January 2017

Stuttering lacunar infarction captured on serial MRIs.

Neurol Clin Pract 2016 Oct;6(5):e37-e39

Stroke Diagnostics and Therapeutics Section (PTF, ANS, RL, JGM), National Institute of Neurological Disorders and Stroke, Bethesda, MD; and Johns Hopkins Community Physicians (JGM), Bethesda, MD.

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http://dx.doi.org/10.1212/CPJ.0000000000000231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100705PMC
October 2016

Identification of Reversible Disruption of the Human Blood-Brain Barrier Following Acute Ischemia.

Stroke 2016 09 26;47(9):2405-8. Epub 2016 Jul 26.

From the Neuro Vascular Brain Imaging Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1161/STROKEAHA.116.013805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111547PMC
September 2016

Long-term Efficacy and Safety of Mepolizumab in Patients With Severe Eosinophilic Asthma: A Multi-center, Open-label, Phase IIIb Study.

Clin Ther 2016 Sep 21;38(9):2058-2070.e1. Epub 2016 Aug 21.

Respiratory Therapeutic Area, GlaxoSmithKline, Research Triangle Park, North Carolina.

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http://dx.doi.org/10.1016/j.clinthera.2016.07.010DOI Listing
September 2016

Chemokine release from human rhinovirus-infected airway epithelial cells promotes fibroblast migration.

J Allergy Clin Immunol 2016 07 13;138(1):114-122.e4. Epub 2016 Feb 13.

Department of Physiology and Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.12.1308DOI Listing
July 2016

Pretreatment blood-brain barrier disruption and post-endovascular intracranial hemorrhage.

Neurology 2016 Jul 17;87(3):263-9. Epub 2016 Jun 17.

From the Neuro Vascular Brain Imaging Unit (R.L.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD; Stanford Stroke Center (S.C., G.W.A., M.G.L.), Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA; Department of Medicine and Neurology (B.C.V.C.), Royal Melbourne Hospital, University of Melbourne, Australia; and Department of Radiology (M.P.M.), Stanford University Medical Center, CA.

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http://dx.doi.org/10.1212/WNL.0000000000002862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955280PMC
July 2016

Imaging Active Intracerebral Hemorrhage After Attempted Endovascular Thrombectomy.

JAMA Neurol 2016 06;73(6):754

National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jamaneurol.2016.0570DOI Listing
June 2016

Blood Flow during Handgrip Exercise in COPD: Effect of Vitamin C.

Med Sci Sports Exerc 2016 Feb;48(2):200-9

1Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, CANADA; 2Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, CANADA; 3Cumming School of Medicine, University of Calgary, Calgary, Alberta, CANADA; 4Department of Medicine, University of Calgary, Calgary, Alberta, CANADA; 5Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, CANADA; 6Department of Cardiac Sciences, University of Calgary, Calgary, Alberta, CANADA; 7Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, CANADA; 8Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, CANADA; and 9Faculty of Kinesiology, University of Calgary, Calgary, Alberta, CANADA.

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http://dx.doi.org/10.1249/MSS.0000000000000766DOI Listing
February 2016

Patterns and Implications of Intracranial Arterial Remodeling in Stroke Patients.

Stroke 2016 Feb 7;47(2):434-40. Epub 2016 Jan 7.

From The Russell H. Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins Hospital, Baltimore, MD (Y.Q., Z.A., J.I., L.L., B.A.W.); Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (S.R.Z., R.L.); and Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (Y.Z., E.G.).

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http://dx.doi.org/10.1161/STROKEAHA.115.009955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729583PMC
February 2016

Rhinovirus in the Pathogenesis and Clinical Course of Asthma.

Chest 2015 Dec;148(6):1508-1516

Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. Electronic address:

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http://dx.doi.org/10.1378/chest.15-1335DOI Listing
December 2015

Significance of Parenchymal Brain Damage in Patients with Critical Illness.

Neurocrit Care 2015 Oct;23(2):243-52

Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Meyer 8-140, 600 N Wolfe St, Baltimore, MD, 21287, USA,

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http://dx.doi.org/10.1007/s12028-015-0110-4DOI Listing
October 2015

Cerebrovascular and ventilatory responses to acute isocapnic hypoxia in healthy aging and lung disease: effect of vitamin C.

J Appl Physiol (1985) 2015 Aug 18;119(4):363-73. Epub 2015 Jun 18.

Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada; Department of Clinical Neuroscience University of Calgary, Calgary, Alberta, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada; Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; and Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada

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http://dx.doi.org/10.1152/japplphysiol.00389.2015DOI Listing
August 2015

Increased ventilatory response to carbon dioxide in COPD patients following vitamin C administration.

ERJ Open Res 2015 May 15;1(1). Epub 2015 Sep 15.

Dept of Physiology and Pharmacology, University of Calgary, Calgary, AB, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, AB, Canada; Dept of Clinical Neuroscience, University of Calgary, Calgary, AB, Canada; Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1183/23120541.00017-2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005137PMC
May 2015

Virus-induced modulation of lower airway diseases: pathogenesis and pharmacologic approaches to treatment.

Pharmacol Ther 2015 Apr 27;148:185-98. Epub 2014 Dec 27.

Airway Inflammation Research Group, Snyder Institute for Chronic Diseases and Department of Physiology & Pharmacology, University of Calgary Faculty of Medicine, Calgary, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2014.12.005DOI Listing
April 2015

Susceptibility-based analysis of dynamic gadolinium bolus perfusion MRI.

Magn Reson Med 2015 Feb 25;73(2):544-54. Epub 2014 Feb 25.

The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; FM Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland.

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http://dx.doi.org/10.1002/mrm.25144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143505PMC
February 2015

Diffusion-perfusion mismatch: an opportunity for improvement in cortical function.

Front Neurol 2014 14;5:280. Epub 2015 Jan 14.

Department of Neurology, Johns Hopkins University School of Medicine , Baltimore, MD , USA.

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http://dx.doi.org/10.3389/fneur.2014.00280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294157PMC
February 2015

Collaterals: an important determinant of prolonged ischemic penumbra versus rapid cerebral infarction?

Front Neurol 2014 14;5:208. Epub 2014 Oct 14.

Department of Neurology, The Johns Hopkins University School of Medicine , Baltimore, MD , USA ; Department of Neurology, Johns Hopkins Bayview Medical Center , Baltimore, MD , USA.

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http://dx.doi.org/10.3389/fneur.2014.00208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196524PMC
October 2014

The roles of occipitotemporal cortex in reading, spelling, and naming.

Cogn Neuropsychol 2014 17;31(5-6):511-28. Epub 2014 Feb 17.

a Department of Neurology , Johns Hopkins University School of Medicine , Baltimore , MD , USA.

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http://dx.doi.org/10.1080/02643294.2014.884060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108518PMC
September 2014

MRI-guided selection of patients for treatment of acute ischemic stroke.

Curr Opin Neurol 2014 Aug;27(4):425-33

aDepartments of Neurology and Radiology bDepartment of Neurology and Neuroscience, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/WCO.0000000000000110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154317PMC
August 2014

Pretreatment blood-brain barrier damage and post-treatment intracranial hemorrhage in patients receiving intravenous tissue-type plasminogen activator.

Stroke 2014 Jul 15;45(7):2030-5. Epub 2014 May 15.

From the Departments of Neurology and Radiology (R.L.), Neurology, Physical Medicine and Rehabilitation and Cognitive Science (A.E.H.), Neurology and Neuroscience (J.W.K.), and Radiology (P.B.B.), Johns Hopkins University, Baltimore, MD; and Department of Radiology, Emory University, Atlanta, GA (S.S.J.).

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http://dx.doi.org/10.1161/STROKEAHA.114.005249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120660PMC
July 2014

Cerebrovascular responses to submaximal exercise in women with COPD.

BMC Pulm Med 2014 Jun 5;14:99. Epub 2014 Jun 5.

Department of Physiology and Pharmacology, Faculty of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1186/1471-2466-14-99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065610PMC
June 2014

Distinct mechanisms and timing of language recovery after stroke.

Cogn Neuropsychol 2013 28;30(7-8):454-75. Epub 2014 Jan 28.

a Russell H. Morgan Department of Radiology and Radiological Science , The Johns Hopkins University School of Medicine , Baltimore , MA , USA.

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http://dx.doi.org/10.1080/02643294.2013.875467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979443PMC
May 2014

Intracranial plaque enhancement in patients with cerebrovascular events on high-spatial-resolution MR images.

Radiology 2014 May 16;271(2):534-42. Epub 2014 Jan 16.

From the Russell H. Morgan Department of Radiology and Radiological Sciences (Y.Q., S.M., B.A.W.) and Department of Neurology (S.R.Z., R.L., V.U., R.W.), Johns Hopkins Hospital, Johns Hopkins University School of Medicine, 367 East Park Building, 600 N Wolfe St, Baltimore, MD 21287.

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http://dx.doi.org/10.1148/radiol.13122812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263625PMC
May 2014

Effects of an anti-TSLP antibody on allergen-induced asthmatic responses.

N Engl J Med 2014 May 20;370(22):2102-10. Epub 2014 May 20.

From the Firestone Institute of Respiratory Health, Department of Medicine, McMaster University, Hamilton, ON (G.M.G., P.M.O.), Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Quebec City, QC (L.-P.B.), Division of Respirology, Critical Care and Sleep Medicine, University of Saskatchewan, Saskatoon, SK (D.C., B.E.D.), Institute for Heart and Lung Health, University of British Columbia, Vancouver (J.M.F.), and Snyder Institute for Chronic Diseases, Faculty of Medicine, Calgary, AB (R.L.) - all in Canada; Amgen, Thousand Oaks, CA (Y.W., M.B., C.D., K.S.G., L.S., E.B., J.R.P.); and Amgen, Seattle (J.B., M.R.C.).

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http://dx.doi.org/10.1056/NEJMoa1402895DOI Listing
May 2014

Pediatric hemiplegic migraine: role of multiple MRI techniques in evaluation of reversible hypoperfusion.

Cephalalgia 2014 Apr 18;34(4):311-5. Epub 2013 Oct 18.

Section of Pediatric Neuroradiology, Division of Pediatric Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/0333102413509432DOI Listing
April 2014

Induction of regulator of G-protein signaling 2 expression by long-acting β2-adrenoceptor agonists and glucocorticoids in human airway epithelial cells.

J Pharmacol Exp Ther 2014 Jan 25;348(1):12-24. Epub 2013 Oct 25.

Airways Inflammation Research Group, Snyder Institute for Chronic Diseases, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada (N.S.H., T.G., C.F.R., A.C., S.S., M.K., R.L., M.A.G., R.N.); GlaxoSmithKline Research and Development, Uxbridge, Middlesex, United Kingdom (M.J.); and Department of Physiology and Pharmacology, School of Medicine, West Virginia University, Morgantown, West Virginia (D.P.S.).

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http://dx.doi.org/10.1124/jpet.113.204586DOI Listing
January 2014

Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia.

J Allergy Clin Immunol 2013 Nov 16;132(5):1086-1096.e5. Epub 2013 Jul 16.

Faculté de médecine, département de médecine, Université Laval, Quebec City, Quebec, Canada. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S009167491300838
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http://dx.doi.org/10.1016/j.jaci.2013.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172321PMC
November 2013

Acute Stroke Imaging Research Roadmap II.

Stroke 2013 Sep 16;44(9):2628-39. Epub 2013 Jul 16.

Department of Radiology, University of Virginia, Charlottesville, VA, USA.

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http://www.thestair.org/sites/default/files/files/Imaging.pd
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http://stroke.ahajournals.org/cgi/doi/10.1161/STROKEAHA.113.
Publisher Site
http://dx.doi.org/10.1161/STROKEAHA.113.002015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040226PMC
September 2013

6p25 microdeletion: white matter abnormalities in an adult patient.

Am J Med Genet A 2013 Jul 17;161A(7):1686-9. Epub 2013 May 17.

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1002/ajmg.a.35937DOI Listing
July 2013

Arrival time correction for dynamic susceptibility contrast MR permeability imaging in stroke patients.

PLoS One 2012 20;7(12):e52656. Epub 2012 Dec 20.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052656PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527589PMC
June 2013

Chronic apraxia of speech and Broca's area.

Stroke 2013 Mar 29;44(3):740-4. Epub 2013 Jan 29.

Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1161/STROKEAHA.112.678508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620682PMC
March 2013

The impact of diurnal variation on induced sputum cell counts in healthy adults.

Clin Transl Allergy 2013 Mar 28;3(1). Epub 2013 Mar 28.

Department of Medicine, University of Calgary, 7007-14th Street SW, Calgary, Alberta, T2V 1P9, Canada.

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http://dx.doi.org/10.1186/2045-7022-3-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621557PMC
March 2013

Cigarette smoke modulates expression of human rhinovirus-induced airway epithelial host defense genes.

PLoS One 2012 12;7(7):e40762. Epub 2012 Jul 12.

Airway Inflammation Research Group, Department of Physiology and Pharmacology, Snyder Institute for Chronic Diseases, University of Calgary Faculty of Medicine, Calgary, Alberta, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040762PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395625PMC
January 2013

Decreased cerebrovascular response to CO2 in post-menopausal females with COPD: role of oxidative stress.

Eur Respir J 2012 Dec 10;40(6):1354-61. Epub 2012 Apr 10.

Faculty of Medicine, University of Calgary, Calgary, ABT2N 4N1, Canada.

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http://dx.doi.org/10.1183/09031936.00197211DOI Listing
December 2012

Neuromuscular transmission failure in myasthenia gravis: decrement of safety factor and susceptibility of extraocular muscles.

Ann N Y Acad Sci 2012 Dec;1275:129-35

Mellen Center for Multiple Sclerosis, Department of Neurology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2012.06841.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539765PMC
December 2012

Ventilatory responses to exercise and CO2 after menopause in healthy women: effects of age and fitness.

Respir Physiol Neurobiol 2012 Oct 28;184(1):1-8. Epub 2012 Jun 28.

Department of Physiology & Pharmacology, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.resp.2012.06.020DOI Listing
October 2012

Lesion analysis of cortical regions associated with the comprehension of Nonreversible and Reversible yes/no questions.

Neuropsychologia 2012 Jul 30;50(8):1946-53. Epub 2012 Apr 30.

Department of Neurology, Johns Hopkins University School of Medicine, 600 North, Wolfe Street, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.neuropsychologia.2012.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518924PMC
July 2012

Rhinovirus-induced MMP-9 expression is dependent on Fra-1, which is modulated by formoterol and dexamethasone.

J Immunol 2012 May 28;188(9):4621-30. Epub 2012 Mar 28.

Airway Inflammation Research Group, Snyder Institute for Chronic Diseases, Department of Medicine, University of Calgary, Calgary, Alberta T2N 4Z6, Canada.

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http://dx.doi.org/10.4049/jimmunol.1101666DOI Listing
May 2012

Formal education, socioeconomic status, and the severity of aphasia after stroke.

Arch Phys Med Rehabil 2011 Nov 15;92(11):1809-13. Epub 2011 Aug 15.

Department of Physical Medicine and Rehabilitation, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.apmr.2011.05.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402236PMC
November 2011

Epithelial cells and airway diseases.

Immunol Rev 2011 Jul;242(1):186-204

Department of Physiology and Pharmacology, University of Calgary Faculty of Medicine, Calgary, AB, Canada.

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http://doi.wiley.com/10.1111/j.1600-065X.2011.01033.x
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http://dx.doi.org/10.1111/j.1600-065X.2011.01033.xDOI Listing
July 2011

Omalizumab: Practical considerations regarding the risk of anaphylaxis.

Allergy Asthma Clin Immunol 2010 Dec 3;6(1):32. Epub 2010 Dec 3.

University of Western Ontario, London, Ontario, Canada and McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1186/1710-1492-6-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006370PMC
December 2010

Effects of budesonide and formoterol on allergen-induced airway responses, inflammation, and airway remodeling in asthma.

J Allergy Clin Immunol 2010 Feb 6;125(2):349-356.e13. Epub 2009 Dec 6.

Firestone Institute for Respiratory Health, Department of Medicine, St Joseph's Healthcare and McMaster University Medical Center, McMaster University, Hamilton, Ontario L8N 3Z5, Canada.

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http://dx.doi.org/10.1016/j.jaci.2009.09.011DOI Listing
February 2010

Ischemia in broca area is associated with broca aphasia more reliably in acute than in chronic stroke.

Stroke 2010 Feb 31;41(2):325-30. Epub 2009 Dec 31.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Md 21287, USA.

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http://dx.doi.org/10.1161/STROKEAHA.109.570374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828050PMC
February 2010