Richard L Dunbar

Richard L Dunbar

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Richard L Dunbar

Richard L Dunbar

Publications by authors named "Richard L Dunbar"

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Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia.

Circulation 2019 Aug 27;140(6):470-486. Epub 2019 Jun 27.

Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (R.L.D.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.039107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686956PMC
August 2019

Apolipoprotein C-II: New findings related to genetics, biochemistry, and role in triglyceride metabolism.

Atherosclerosis 2017 Dec 20;267:49-60. Epub 2017 Oct 20.

Lipoprotein Metabolism Section, Cardio-Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705268PMC
December 2017

Oral Apolipoprotein A-I Mimetic D-4F Lowers HDL-Inflammatory Index in High-Risk Patients: A First-in-Human Multiple-Dose, Randomized Controlled Trial.

Clin Transl Sci 2017 Nov 9;10(6):455-469. Epub 2017 Aug 9.

Department of Medicine, Division of Translational Medicine and Human Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/cts.12487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673907PMC
November 2017

Genetic coding variants in the niacin receptor, hydroxyl-carboxylic acid receptor 2, and response to niacin therapy.

Pharmacogenet Genomics 2017 08;27(8):285-293

Departments of aMedicine bBiostatistics and Epidemiology cGenetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania dDepartment of Medicine, Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington, Seattle, Washington eDepartment of Pharmacology and Medicine, University of Tennessee, Knoxville, Tennessee fSt Peter's Health Partners, Kingston, New York, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548439PMC
August 2017

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.

N Engl J Med 2017 07 24;377(3):211-221. Epub 2017 May 24.

From Regeneron Genetics Center (F.E.D., C.O., C.S., O.G., S.M., C.V.V.H., S.B., L.H., A.L., J.P., N.S., A.J.M., J.D.O., J.G.R., A.R.S., I.B.B., T.M.T., G.D.Y., S.J.M., A. Baras) and Regeneron Pharmaceuticals (V.G., H.M.D., A.Z., W.S., N.S., A.J.M., S.H., A. Bouzelmat, R.Z., B.S., R.P., D.G., G.A.H., W.J.S., P.B., G.D.Y., S.J.M., J.G.) Tarrytown, NY; the Department of Medicine, Division of Translational Medicine and Human Genetics (R.L.D.), and Departments of Surgery (S.D.) and Genetics and Medicine (A.S., D.J.R.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, and Geisinger Health System, Danville (J.B.L., M.F.M., M.D.R., H.L.K., D.H.L., D.J.C.) - both in Pennsylvania; the Division of Endocrinology and Metabolism, Department of Internal Medicine (W.H.H.S., I.-T.L.) and Cardiovascular Center (K.-W.L.), Taichung Veterans General Hospital, Institute of Medical Technology, National Chung-Hsing University (W.H.H.S.), School of Medicine, Chung Shan Medical University (I.-T.L.), and the Department of Medicine, China Medical University (K.-W.L.), Taichung, and School of Medicine, National Yang-Ming University (W.H.H.S., I.-T.L., K.-W.L.), and School of Medicine, National Defense Medical Center (W.H.H.S.), Taipei - all in Taiwan; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA (X.G., J.I.R., Y.-D.I.C.); the Division of Cardiology, Department of Medicine, Molecular Physiology Institute, School of Medicine, Duke University, Durham, NC (W.E.K., S.H.S.); the Department of Clinical Biochemistry, Rigshospitalet (A.B.W., B.G.N., A.T.-H.), the Copenhagen General Population Study (B.G.N., A.T.-H.) and Department of Clinical Biochemistry (B.G.N.), Herlev and Gentofte Hospital, and the Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, and Faculty of Health and Medical Sciences, University of Copenhagen (B.G.N., A.T.-H.) - all in Copenhagen; and TNO Metabolic Health Research, Gaubius Laboratory, Leiden, the Netherlands (A.M.H., H.M.G.P.).

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http://dx.doi.org/10.1056/NEJMoa1612790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800308PMC
July 2017

Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein.

Arterioscler Thromb Vasc Biol 2016 05 10;36(5):994-1002. Epub 2016 Mar 10.

From the Columbia University, New York, NY (G.R.-S., C.N., E.C., D.S.D., W.K., R.R., S.H., T.T., H.N.G.); University of Pennsylvania, Philadelphia (J.S.M., R.L.D., E.M.d., A.L.B., D.J.R.); Merck & Co., Inc., Kenilworth, NJ (P.J., A.O.J.-L., J.A.W., Y.L., M.E.L., D.E.G.); Tufts University School of Medicine, Boston, MA (B.A.); and Drexel Neurological Associates, Philadelphia, PA (H.R.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911016PMC
May 2016

Niacin Alternatives for Dyslipidemia: Fool's Gold or Gold Mine? Part II: Novel Niacin Mimetics.

Curr Atheroscler Rep 2016 Apr;18(4):17

Department of Medicine, Division of Cardiovascular Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s11883-016-0570-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773474PMC
April 2016

Niacin Alternatives for Dyslipidemia: Fool's Gold or Gold Mine? Part I: Alternative Niacin Regimens.

Curr Atheroscler Rep 2016 Feb;18(2):11

Department of Medicine, York Hospital, 1001 S. George Street, York, PA, 17403, USA.

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http://dx.doi.org/10.1007/s11883-016-0563-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753247PMC
February 2016

Effects of niacin, statin, and fenofibrate on circulating proprotein convertase subtilisin/kexin type 9 levels in patients with dyslipidemia.

Am J Cardiol 2015 Jan 31;115(2):178-82. Epub 2014 Oct 31.

Department of Medicine, Smilow Center for Translational Research, Perelman School of Medicine, Philadelphia, Pennsylvania; Cardiovascular Institute, Smilow Center for Translational Research, Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.amjcard.2014.10.018DOI Listing
January 2015

Discordance between non-HDL-cholesterol and LDL-particle measurements: results from the Multi-Ethnic Study of Atherosclerosis.

Atherosclerosis 2013 Aug 26;229(2):517-23. Epub 2013 Mar 26.

Division of Cardiovascular Medicine, Perelman School of Medicine at the University of Pennsylvania, PA, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066302PMC
August 2013

Differences in absolute risk of cardiovascular events using risk-refinement tests: a systematic analysis of four cardiovascular risk equations.

Atherosclerosis 2013 Mar 31;227(1):172-7. Epub 2012 Dec 31.

Division of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, PA, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.12.025DOI Listing
March 2013

Extended-release niacin acutely suppresses postprandial triglyceridemia.

Am J Med 2012 Oct 25;125(10):1026-35. Epub 2012 Jul 25.

Department of Medicine, Division of Translational Medicine and Human Genetics, Perelman School of Medicine at the University of Pennsylvania, and the University of Pennsylvania Health System, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.amjmed.2012.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170918PMC
October 2012

Intraindividual variability of C-reactive protein: the Multi-Ethnic Study of Atherosclerosis.

Atherosclerosis 2012 Sep 20;224(1):274-9. Epub 2012 Jul 20.

Division of Cardiovascular Medicine, University of Pennsylvania, Perelman Center for Advanced Medicine, Heart and Vascular Center, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085141PMC
September 2012

Seeing red: flushing out instigators of niacin-associated skin toxicity.

J Clin Invest 2010 Aug 26;120(8):2651-5. Epub 2010 Jul 26.

Department of Medicine, Division of Experimental Therapeutics, Institute for Translational Medicine and Therapeutics, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1172/JCI44098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912206PMC
August 2010

Could exercise metabolomics pave the way for gymnomimetics?

Sci Transl Med 2010 Jul;2(41):41ps35

Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/scitranslmed.3001188DOI Listing
July 2010

Demystifying triglycerides: a practical approach for the clinician.

Cleve Clin J Med 2005 Aug;72(8):661-6, 670-2, 674-5 passim

Cardiovascular Risk Intervention Program, University of Pennsylvania School of Medicine, Philadelphia, USA.

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http://dx.doi.org/10.3949/ccjm.72.8.661DOI Listing
August 2005

The unsung perils of peripheral arterial disease: a malady in search of a patient.

Prev Cardiol 2005 ;8(2):108-13; quiz 114-5

University of Pennsylvania Medical School, Philadelphia, PA 19104, USA.

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June 2005

Current Drug Options for Raising HDL Cholesterol.

Curr Treat Options Cardiovasc Med 2005 May;7(1):15-23

University of Pennsylvania School of Medicine and Children’s Hospital of Philadelphia, PHI building, Suite 351, 39th and Market Streets, Philadelphia, PA 19104, USA.

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May 2005