Publications by authors named "Richard J Young"

40Publications

Validation of local p16 testing for determination of human papilloma virus status eligibility on a low risk oropharyngeal cancer trial - A Trans-Tasman Radiation Oncology Group study.

Authors:
Richard J Young Benjamin Solomon June Corry Christopher Angel Lizbeth Kenny Sandro Porceddu Christopher Wratten Andrew Macann James E Jackson Alan Herschtal Danny Rischin

Oral Oncol 2020 11 1;110:104988. Epub 2020 Sep 1.

Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia. Electronic address:

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November 2020

Validation and characterisation of prognostically significant PD-L1 immune cells in HPV+ oropharyngeal squamous cell carcinoma.

Authors:
Richard J Young Mathias Bressel Sandro Porceddu Janez Cernelc Peter Savas Howard Liu Damien Urban Alesha A Thai Caroline Cooper Tsien Fua Paul Neeson Danny Rischin Benjamin Solomon

Oral Oncol 2020 02 12;101:104516. Epub 2019 Dec 12.

Research Division, Peter MacCallum Cancer Centre, Melbourne, Australia; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia. Electronic address:

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February 2020

A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy.

Authors:
Emily J Lelliott Carleen Cullinane Claire A Martin Rachael Walker Kelly M Ramsbottom Fernando Souza-Fonseca-Guimaraes Shatha Abuhammad Jessica Michie Laura Kirby Richard J Young Alison Slater Peter Lau Katrina Meeth Jane Oliaro Nicole Haynes Grant A McArthur Karen E Sheppard

Sci Rep 2019 02 4;9(1):1225. Epub 2019 Feb 4.

Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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February 2019

Minimotifs dysfunction is pervasive in neurodegenerative disorders.

Authors:
Surbhi Sharma Richard J Young Jingchun Chen Xiangning Chen Edwin C Oh Martin R Schiller

Alzheimers Dement (N Y) 2018 25;4:414-432. Epub 2018 Jul 25.

Nevada Institute of Personalized Medicine, Las Vegas, NV, USA.

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July 2018

Unilateral radiotherapy treatment for p16/human papillomavirus-positive squamous cell carcinoma of unknown primary in the head and neck.

Authors:
Albert Tiong Danny Rischin Richard J Young Alan Herschtal Ben Solomon Ieta D'Costa Tsien Fua Chen Liu Andrew Coleman Stephen Kleid Benjamin J Dixon June Corry

Laryngoscope 2018 09 26;128(9):2076-2083. Epub 2018 Feb 26.

University of Melbourne, Parkville, Victoria, Australia.

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September 2018

Prognostic Significance of PD-L1 and CD8 Immune Cells in HPV Oropharyngeal Squamous Cell Carcinoma.

Authors:
Benjamin Solomon Richard J Young Mathias Bressel Damien Urban Shona Hendry Alesha Thai Christopher Angel Afaf Haddad Marcin Kowanetz Tsien Fua June Corry Stephen Fox Danny Rischin

Cancer Immunol Res 2018 03 29;6(3):295-304. Epub 2018 Jan 29.

Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.

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March 2018

Head and neck squamous cell carcinoma: Genomics and emerging biomarkers for immunomodulatory cancer treatments.

Authors:
Benjamin Solomon Richard J Young Danny Rischin

Semin Cancer Biol 2018 10 31;52(Pt 2):228-240. Epub 2018 Jan 31.

Department of Medical Oncology, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, Victoria 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3052, Australia.

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October 2018

Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance.

Authors:
Claire A Martin Carleen Cullinane Laura Kirby Shatha Abuhammad Emily J Lelliott Kelly Waldeck Richard J Young Natalie Brajanovski Donald P Cameron Rachael Walker Elaine Sanij Gretchen Poortinga Ross D Hannan Richard B Pearson Rodney J Hicks Grant A McArthur Karen E Sheppard

Int J Cancer 2018 05 3;142(10):2139-2152. Epub 2018 Jan 3.

Cancer Research Division, Peter MacCallum Cancer Centre, East Melbourne, Vic, Australia.

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May 2018

Comparison of Four PD-L1 Immunohistochemical Assays in Lung Cancer.

Authors:
Shona Hendry David J Byrne Gavin M Wright Richard J Young Sue Sturrock Wendy A Cooper Stephen B Fox

J Thorac Oncol 2018 03 23;13(3):367-376. Epub 2017 Nov 23.

Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.

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March 2018

Minimotif Miner 4: a million peptide minimotifs and counting.

Authors:
Kenneth F Lyon Xingyu Cai Richard J Young Abdullah-Al Mamun Sanguthevar Rajasekaran Martin R Schiller

Nucleic Acids Res 2018 01;46(D1):D465-D470

Nevada Institute of Personalized Medicine and School of Life Sciences, University of Nevada, Las Vegas, 89154 4004 NV, USA.

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January 2018

The role of human papillomavirus in p16-positive oral cancers.

Authors:
Simone Belobrov Alyssa M Cornall Richard J Young Kendrick Koo Christopher Angel David Wiesenfeld Danny Rischin Suzanne M Garland Michael McCullough

J Oral Pathol Med 2018 Jan 30;47(1):18-24. Epub 2017 Oct 30.

Melbourne Dental School, Faculty of Medicine Dentistry and Health Science, The University of Melbourne, Melbourne, VIC, Australia.

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January 2018

Cisplatin Increases Sensitivity to FGFR Inhibition in Patient-Derived Xenograft Models of Lung Squamous Cell Carcinoma.

Authors:
Clare E Weeden Aliaksei Z Holik Richard J Young Stephen B Ma Jean-Marc Garnier Stephen B Fox Phillip Antippa Louis B Irving Daniel P Steinfort Gavin M Wright Prudence A Russell Matthew E Ritchie Christopher J Burns Benjamin Solomon Marie-Liesse Asselin-Labat

Mol Cancer Ther 2017 08 13;16(8):1610-1622. Epub 2017 Jun 13.

ACRF Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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August 2017

Glut-1 expression in small cervical biopsies is prognostic in cervical cancers treated with chemoradiation.

Authors:
Yada Kanjanapan Siddhartha Deb Richard J Young Mathias Bressel Linda Mileshkin Danny Rischin Michael S Hofman Kailash Narayan Shankar Siva

Clin Transl Radiat Oncol 2017 Feb 8;2:53-58. Epub 2017 Feb 8.

Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.

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February 2017

Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non-small cell lung cancer.

Authors:
Cristina Gamell Twishi Gulati Yaara Levav-Cohen Richard J Young Hongdo Do Pat Pilling Elena Takano Neil Watkins Stephen B Fox Prudence Russell Doron Ginsberg Brendon J Monahan Gavin Wright Alex Dobrovic Sue Haupt Ben Solomon Ygal Haupt

Sci Signal 2017 01 10;10(461). Epub 2017 Jan 10.

Tumour Suppression Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.

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January 2017

CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity.

Authors:
Samantha E Boyle Clare G Fedele Vincent Corbin Elisha Wybacz Pacman Szeto Jeremy Lewin Richard J Young Annie Wong Robert Fuller John Spillane David Speakman Simon Donahoe Miklos Pohl David Gyorki Michael A Henderson Ricky W Johnstone Anthony T Papenfuss Mark Shackleton

Cancer Res 2016 07 20;76(13):3965-77. Epub 2016 Jun 20.

Cancer Development and Treatment Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Australia. Sir Peter MacCallum Department of Pathology, University of Melbourne, Parkville, Australia. Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia. Department of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Australia.

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July 2016

p16-positive lymph node metastases from cutaneous head and neck squamous cell carcinoma: No association with high-risk human papillomavirus or prognosis and implications for the workup of the unknown primary.

Authors:
Lachlan J McDowell Richard J Young Meredith L Johnston Tze-Jian Tan Stephen Kleid Chen S Liu Mathias Bressel Vanessa Estall Danny Rischin Benjamin Solomon June Corry

Cancer 2016 Apr 16;122(8):1201-8. Epub 2016 Feb 16.

Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Australia.

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April 2016

Quantitative and qualitative analysis of [(18)F]FDG and [(18)F]FAZA positron emission tomography of head and neck cancers and associations with HPV status and treatment outcome.

Authors:
Edward E Graves Rodney J Hicks David Binns Mathias Bressel Quynh-Thu Le Lester Peters Richard J Young Danny Rischin

Eur J Nucl Med Mol Imaging 2016 Apr 18;43(4):617-25. Epub 2015 Nov 18.

Division of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Australia.

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April 2016

Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.

Authors:
Francis W Hunter Richard J Young Zvi Shalev Ravi N Vellanki Jingli Wang Yongchuan Gu Naveen Joshi Sreevalsan Sreebhavan Ilan Weinreb David P Goldstein Jason Moffat Troy Ketela Kevin R Brown Marianne Koritzinsky Benjamin Solomon Danny Rischin William R Wilson Bradly G Wouters

Cancer Res 2015 Oct 21;75(19):4211-23. Epub 2015 Aug 21.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. Ontario Institute for Cancer Research, Toronto, Ontario, Canada.

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October 2015

The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma.

Authors:
Rachel Ramsdale Robert N Jorissen Frederic Z Li Sheren Al-Obaidi Teresa Ward Karen E Sheppard Patricia E Bukczynska Richard J Young Samantha E Boyle Mark Shackleton Gideon Bollag Georgina V Long Eugene Tulchinsky Helen Rizos Richard B Pearson Grant A McArthur Amardeep S Dhillon Petranel T Ferrao

Sci Signal 2015 Aug 18;8(390):ra82. Epub 2015 Aug 18.

Molecular Oncology Laboratory, Peter MacCallum Cancer Centre, St. Andrew's Place, East Melbourne, Victoria 3002, Australia. Oncogenic Signalling and Growth Control Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia. Sir Peter MacCallum Department of Oncology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Victoria 3010, Australia. Cancer Therapeutics Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia. Department of Pathology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Victoria 3010, Australia.

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August 2015

¹⁸F-FDG PET/CT following chemoradiation of uterine cervix cancer provides powerful prognostic stratification independent of HPV status: a prospective cohort of 105 women with mature survival data.

Authors:
Shankar Siva Siddhartha Deb Richard J Young Rodney J Hicks Jason Callahan Mathias Bressel Linda Mileshkin Danny Rischin David Bernshaw Kailash Narayan

Eur J Nucl Med Mol Imaging 2015 Nov 15;42(12):1825-32. Epub 2015 Jul 15.

Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, St Andrews Street, East Melbourne, 3002, Victoria, Australia.

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November 2015