Richard J Cornall

Richard J Cornall

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Richard J Cornall

Richard J Cornall

Publications by authors named "Richard J Cornall"

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Immune Checkpoints as Therapeutic Targets in Autoimmunity.

Front Immunol 2018 8;9:2306. Epub 2018 Oct 8.

MRC Human Immunology Unit, University of Oxford, Oxford, United Kingdom.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02306
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http://dx.doi.org/10.3389/fimmu.2018.02306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186808PMC
September 2019

Partial retinal photoreceptor loss in a transgenic mouse model associated with reduced levels of interphotoreceptor retinol binding protein (IRBP, RBP3).

Exp Eye Res 2018 07 21;172:54-65. Epub 2018 Mar 21.

Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK; University of Western Australia, Lions Eye Institute, Perth, Western Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2018.03.020DOI Listing
July 2018

B1a B cells require autophagy for metabolic homeostasis and self-renewal.

J Exp Med 2018 02 11;215(2):399-413. Epub 2018 Jan 11.

Kennedy Institute of Rheumatology and Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, England, UK

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http://dx.doi.org/10.1084/jem.20170771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789411PMC
February 2018

Themis2: setting the threshold for B-cell selection.

Cell Mol Immunol 2017 08 19;14(8):643-645. Epub 2017 Jun 19.

MRC Human Immunology Unit, Weatherall Institute for Molecular Medicine, Nuffield Department of Medicine, University of Oxford, Oxford OX3 9DS, UK.

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http://dx.doi.org/10.1038/cmi.2017.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549605PMC
August 2017

Themis2 lowers the threshold for B cell activation during positive selection.

Nat Immunol 2017 02 19;18(2):205-213. Epub 2016 Dec 19.

MRC Human Immunology Unit, Weatherall Institute for Molecular Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ni.3642DOI Listing
February 2017

Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection.

Proc Natl Acad Sci U S A 2015 Oct 5;112(42):E5706-14. Epub 2015 Oct 5.

Department of Genetics, The Scripps Research Institute, La Jolla, CA 92037; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390

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http://dx.doi.org/10.1073/pnas.1515619112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620900PMC
October 2015

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.

J Exp Med 2014 Dec 24;211(13):2549-66. Epub 2014 Nov 24.

Laboratory of Host Defenses, Laboratory of Systems Biology, Laboratory of Immunology, and Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892

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http://dx.doi.org/10.1084/jem.20141307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267229PMC
December 2014

DOCK8 is critical for the survival and function of NKT cells.

Blood 2013 Sep 8;122(12):2052-61. Epub 2013 Aug 8.

Medical Research Council Human Immunology Unit, Weatherall Institute for Molecular Medicine, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom;

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http://dx.doi.org/10.1182/blood-2013-02-482331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778549PMC
September 2013

The phenotype of circulating follicular-helper T cells in patients with rheumatoid arthritis defines CD200 as a potential therapeutic target.

Clin Dev Immunol 2012 4;2012:948218. Epub 2012 Oct 4.

School of Medicine and Pharmacology, Sir Charles Gairdner Hospital, The University of Western Australia, 4th Floor G Block, Hospital Avenue, Nedlands, Perth, WA 6009, Australia.

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http://www.hindawi.com/journals/jir/2012/948218/
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http://dx.doi.org/10.1155/2012/948218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471455PMC
May 2013

The high-risk corneal regraft model: a justification for tissue matching in humans.

Transpl Int 2013 Apr 11;26(4):453-61. Epub 2013 Feb 11.

Section of Immunology and Infection, Division of Applied Medicine, University of Aberdeen, Aberdeen, UK.

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http://doi.wiley.com/10.1111/tri.12055
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http://dx.doi.org/10.1111/tri.12055DOI Listing
April 2013

DOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memory.

Eur J Immunol 2011 Dec 10;41(12):3423-35. Epub 2011 Nov 10.

Nuffield Department of Medicine, Henry Wellcome Building of Molecular Physiology, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1002/eji.201141759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517112PMC
December 2011

The essential role of DOCK8 in humoral immunity.

Dis Markers 2010 ;29(3-4):141-50

John Curtin School of Medical Research, The Australian National University, Canberra ACT, Australia.

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http://dx.doi.org/10.3233/DMA-2010-0739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835290PMC
April 2011

HO-1 extends to stem cells.

Blood 2008 Dec;112(12):4363-4

University of Oxford.

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http://dx.doi.org/10.1182/blood-2008-06-163055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597115PMC
December 2008

Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells.

J Immunol 2008 Mar;180(6):3889-99

Department of Ophthalmology, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.180.6.3889DOI Listing
March 2008

MyD88-dependent autoimmune disease in Lyn-deficient mice.

Eur J Immunol 2007 Oct;37(10):2734-43

Henry Wellcome Building of Molecular Physiology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/eji.200737293DOI Listing
October 2007

Increased positive selection of B1 cells and reduced B cell tolerance to intracellular antigens in c1q-deficient mice.

J Immunol 2007 Mar;178(5):2916-22

Henry Wellcome Building for Molecular Physiology, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.178.5.2916DOI Listing
March 2007

Spontaneous class switching and B cell hyperactivity increase autoimmunity against intracellular self antigen in Lyn-deficient mice.

Eur J Immunol 2006 Nov;36(11):2920-7

Henry Wellcome Building for Molecular Physiology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/eji.200636462DOI Listing
November 2006

Spontaneous B cell hyperactivity in autoimmune-prone MRL mice.

Int Immunol 2006 Jul 30;18(7):1127-37. Epub 2006 May 30.

Henry Wellcome Building of Molecular Physiology, Oxford University, Roosevelt Drive, Oxford, OX3 7BN, UK.

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http://dx.doi.org/10.1093/intimm/dxl047DOI Listing
July 2006

TLR4, TLR9 and MyD88 are not required for the positive selection of autoreactive B cells into the primary repertoire.

Eur J Immunol 2006 Jun;36(6):1404-12

Henry Wellcome Building of Molecular Physiology, University of Oxford, UK.

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http://dx.doi.org/10.1002/eji.200636019DOI Listing
June 2006

Signals from a self-antigen induce positive selection in early B cell ontogeny but are tolerogenic in adults.

J Immunol 2006 Jun;176(12):7402-11

Henry Wellcome Building of Molecular Physiology, University of Oxford, UK.

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http://dx.doi.org/10.4049/jimmunol.176.12.7402DOI Listing
June 2006

B-cell tolerance.

Transplantation 2006 Feb;81(3):308-15

Henry Wellcome Building of Molecular Physiology, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1097/01.tp.0000203830.79357.39DOI Listing
February 2006

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity.

Nature 2005 May;435(7041):452-8

Division of Immunology and Genetics, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.

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http://dx.doi.org/10.1038/nature03555DOI Listing
May 2005

Analysis of B-cell immune tolerance induction using transgenic mice.

Methods Mol Biol 2004 ;271:239-60

Nuffield Department of Clinical Medicine, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1385/1-59259-796-3:239DOI Listing
July 2004

The cellular location of self-antigen determines the positive and negative selection of autoreactive B cells.

J Exp Med 2003 Nov;198(9):1415-25

Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1084/jem.20030279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194246PMC
November 2003

Isotype control of B cell signaling.

Sci STKE 2003 May 27;2003(184):pe21. Epub 2003 May 27.

Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1126/stke.2003.184.pe21DOI Listing
May 2003