Richard J Cook

Richard J Cook

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Richard J Cook

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Testing the heritability and parent-of-origin hypotheses for ages at onset of psoriatic arthritis under biased sampling.

Biometrics 2020 Mar 19;76(1):293-303. Epub 2019 Aug 19.

School of Statistics and Management, Shanghai University of Finance and Economics, Shanghai, China.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/biom.13138
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http://dx.doi.org/10.1111/biom.13138DOI Listing
March 2020

Mitigating bias from intermittent measurement of time-dependent covariates in failure time analysis.

Stat Med 2020 Mar 3. Epub 2020 Mar 3.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario.

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http://dx.doi.org/10.1002/sim.8517DOI Listing
March 2020

Assessing the accuracy of predictive models with interval-censored data.

Biostatistics 2020 Mar 13. Epub 2020 Mar 13.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON N2L 3G1, Canada.

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http://dx.doi.org/10.1093/biostatistics/kxaa011DOI Listing
March 2020

Multistate analysis from cross-sectional and auxiliary samples.

Stat Med 2020 Feb 10;39(4):387-408. Epub 2019 Dec 10.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada.

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http://dx.doi.org/10.1002/sim.8411DOI Listing
February 2020

The association between synovial fluid serine proteinase activity and response to intra-articular corticosteroid injection in psoriatic arthritis.

Clin Rheumatol 2020 Feb 25. Epub 2020 Feb 25.

Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, Krembil Research Institute, University Health Network, University of Toronto, 399 Bathurst Street 1E-416, Toronto, Ontario, M5T 2S8, Canada.

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http://dx.doi.org/10.1007/s10067-020-05003-9DOI Listing
February 2020

Remission in psoriatic arthritis: Definition and predictors.

Semin Arthritis Rheum 2020 Feb 3. Epub 2020 Feb 3.

Division of Rheumatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Psoriatic Arthritis Program, University Health Network, Centre for Prognosis Studies in The Rheumatic Diseases, Toronto Western hospital, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2020.01.012DOI Listing
February 2020

Identifying patterns of alcohol use among secondary school students in Canada: A multilevel latent class analysis.

Addict Behav 2020 Jan 5;100:106120. Epub 2019 Sep 5.

School of Public Health and Health Systems, University of Waterloo, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.addbeh.2019.106120DOI Listing
January 2020

Gene-based association analysis of survival traits via functional regression-based mixed effect cox models for related samples.

Genet Epidemiol 2019 12 10;43(8):952-965. Epub 2019 Sep 10.

Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, Washington, District of Columbia.

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http://dx.doi.org/10.1002/gepi.22254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829032PMC
December 2019

On estimands arising from misspecified semiparametric rate-based analysis of recurrent episodic conditions.

Stat Med 2019 11 20;38(25):4977-4998. Epub 2019 Aug 20.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1002/sim.8345DOI Listing
November 2019

Independence conditions and the analysis of life history studies with intermittent observation.

Biostatistics 2019 Nov 11. Epub 2019 Nov 11.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON N2L 3G1, Canada.

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http://dx.doi.org/10.1093/biostatistics/kxz047DOI Listing
November 2019

The illness-death model for family studies.

Biostatistics 2019 Nov 19. Epub 2019 Nov 19.

Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada.

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http://dx.doi.org/10.1093/biostatistics/kxz048DOI Listing
November 2019

A new perspective on loss to follow-up in failure time and life history studies.

Stat Med 2019 10 24;38(23):4583-4610. Epub 2019 Jul 24.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1002/sim.8318DOI Listing
October 2019

Liver Abnormalities in Patients with Psoriatic Arthritis.

J Rheumatol 2019 Oct 15. Epub 2019 Oct 15.

From the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada; Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada; Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada; University of Toronto, Department of Medicine, Division of Rheumatology, University of Toronto, Co-Director, Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, Canada; Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, Senior Scientist, Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada. Address correspondence to Dr. Dafna D. Gladman Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, Krembil Research Institute, University Health Network, 399 Bathurst Street, 1E410B, Toronto, Ontario, Canada M5T 2S8. Email:

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http://dx.doi.org/10.3899/jrheum.181312DOI Listing
October 2019

Dependence modeling for multi-type recurrent events via copulas.

Stat Med 2019 09 24;38(21):4066-4082. Epub 2019 Jun 24.

Department of Statistics and Actuarial Science, University of Waterloo, ON, Canada.

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http://dx.doi.org/10.1002/sim.8283DOI Listing
September 2019

Identifying trajectories of alcohol use in a sample of secondary school students in Ontario and Alberta: longitudinal evidence from the COMPASS study.

Health Promot Chronic Dis Prev Can 2019 Sep;39(8-9):244-253

School of Public Health and Health Systems, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.24095/hpcdp.39.8/9.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756132PMC
September 2019

Copula-based score test for bivariate time-to-event data, with application to a genetic study of AMD progression.

Lifetime Data Anal 2019 07 17;25(3):546-568. Epub 2018 Dec 17.

Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/s10985-018-09459-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559827PMC
July 2019

Score tests based on a finite mixture model of Markov processes under intermittent observation.

Stat Med 2019 07 10;38(16):3013-3025. Epub 2019 Apr 10.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Canada.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/sim.8155
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http://dx.doi.org/10.1002/sim.8155DOI Listing
July 2019

Response to: 'Can biomarkers differentiate psoriatic arthritis from osteoarthritis?' by Tian .

Ann Rheum Dis 2019 Jul 4. Epub 2019 Jul 4.

Department of Medicine, Rheumatology, University of Toronto, Toronto, Ontario, Canada

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http://dx.doi.org/10.1136/annrheumdis-2019-215762DOI Listing
July 2019

Serum-based soluble markers differentiate psoriatic arthritis from osteoarthritis.

Ann Rheum Dis 2019 06 25;78(6):796-801. Epub 2019 Mar 25.

Division of Rheumatology, Department of Medicine, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada

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http://dx.doi.org/10.1136/annrheumdis-2018-214737DOI Listing
June 2019

The effect of omitted covariates in marginal and partially conditional recurrent event analyses.

Lifetime Data Anal 2019 04 16;25(2):280-300. Epub 2018 May 16.

Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.

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http://dx.doi.org/10.1007/s10985-018-9430-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423006PMC
April 2019

Comparison Between INSPIRE and Domjan method for measuring lumbar lateral flexion in patients of psoriatic arthritis (PsA) and correlation with radiographic damage.

Clin Rheumatol 2019 Apr 29;38(4):1063-1066. Epub 2018 Nov 29.

Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s10067-018-4375-9DOI Listing
April 2019

The association between blood donor sex and age and transfusion recipient mortality: an exploratory analysis.

Transfusion 2019 02 10;59(2):482-491. Epub 2018 Nov 10.

McMaster Centre for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.

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http://doi.wiley.com/10.1111/trf.15011
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http://dx.doi.org/10.1111/trf.15011DOI Listing
February 2019

Observing Blood Management Programs through the Retrospectroscope.

Anesthesiology 2018 12;129(6):1060-1062

From the Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada (R.J.C.) the Department of Anesthesia and Perioperative Care, University of California, San Francisco, California (R.B.W.).

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http://dx.doi.org/10.1097/ALN.0000000000002477DOI Listing
December 2018

Systematic reviews of guidelines and studies for single versus multiple unit transfusion strategies.

Transfusion 2018 12 21;58(12):2841-2860. Epub 2018 Oct 21.

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1111/trf.14952DOI Listing
December 2018

Tracing studies in cohorts with attrition: Selection models for efficient sampling.

Stat Med 2018 07 16;37(15):2354-2366. Epub 2018 Apr 16.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada.

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http://dx.doi.org/10.1002/sim.7646DOI Listing
July 2018

Design of cancer trials based on progression-free survival with intermittent assessment.

Stat Med 2018 05 26;37(12):1947-1959. Epub 2018 Mar 26.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON N2L 3G1, Canada.

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http://dx.doi.org/10.1002/sim.7641DOI Listing
May 2018

Genome-wide analysis of disease progression in age-related macular degeneration.

Hum Mol Genet 2018 03;27(5):929-940

Division of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC University of Pittsburgh, Pittsburgh, PA 15224, USA.

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http://dx.doi.org/10.1093/hmg/ddy002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059197PMC
March 2018

Variable selection and prediction in biased samples with censored outcomes.

Lifetime Data Anal 2018 01 18;24(1):72-93. Epub 2017 Feb 18.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.

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http://dx.doi.org/10.1007/s10985-017-9392-5DOI Listing
January 2018

Sensitivity and Specificity of Radiographic Scoring Instruments for Detecting Change in Axial Psoriatic Arthritis.

Arthritis Care Res (Hoboken) 2017 11 21;69(11):1700-1705. Epub 2017 Sep 21.

Centre for Prognosis Studies in the Rheumatic Diseases-Toronto Western Hospital, Krembil Research Institute, University Health Network, and University of Toronto, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/acr.23189
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http://dx.doi.org/10.1002/acr.23189DOI Listing
November 2017

Comparison of Spot Urine Protein to Creatinine Ratio to 24-Hour Proteinuria to Identify Important Change Over Time in Proteinuria in Lupus.

J Clin Rheumatol 2017 Sep;23(6):301-307

From the *University of Toronto Lupus Clinic, Toronto Western Hospital, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto; and †Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1097/RHU.0000000000000557DOI Listing
September 2017

Second-Order Estimating Equations for Clustered Current Status Data from Family Studies Using Response-Dependent Sampling.

Stat Biosci 2018 24;10(1):160-183. Epub 2017 Jul 24.

2Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON N2L 3G1 Canada.

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http://dx.doi.org/10.1007/s12561-017-9201-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097126PMC
July 2017

A two-phase model for chronic disease processes under intermittent inspection.

Stat Med 2017 06 26;36(13):2016-2031. Epub 2017 Feb 26.

Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, Waterloo, N2L 3G1, ON, Canada.

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http://dx.doi.org/10.1002/sim.7269DOI Listing
June 2017

Demonstrating therapeutic equivalence of a new and established pharmaceutical or intervention: a guide for the non-statistician.

Transfusion 2017 06 27;57(6):1343-1346. Epub 2017 Mar 27.

Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1111/trf.14061DOI Listing
June 2017

Identification of liver metastases with probe-based confocal laser endomicroscopy at two excitation wavelengths.

Lasers Surg Med 2017 03 19;49(3):280-292. Epub 2016 Dec 19.

UCL Centre for Advanced Biomedical Imaging, Paul O'Gorman Building, University College London, 72 Huntley Street, London, WC1E 6DD, UK.

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http://dx.doi.org/10.1002/lsm.22617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396307PMC
March 2017

Short-Term versus Long-Term Blood Storage.

N Engl J Med 2017 03;376(11):1092-3

Population Health Research Institute, Hamilton, ON, Canada

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http://dx.doi.org/10.1056/NEJMc1700464DOI Listing
March 2017

Understanding non-inferiority trials and tests for the non-statistician: when to use them and how to interpret them.

Transfusion 2017 02 10;57(2):240-243. Epub 2016 Nov 10.

Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1111/trf.13922DOI Listing
February 2017

Goodness-of-fit test for monotone proportional subdistribution hazards assumptions based on weighted residuals.

Stat Med 2017 01 28;36(2):362-377. Epub 2016 Oct 28.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON N2L 3G1, Canada.

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http://doi.wiley.com/10.1002/sim.7153
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http://dx.doi.org/10.1002/sim.7153DOI Listing
January 2017

Effect of Short-Term vs. Long-Term Blood Storage on Mortality after Transfusion.

N Engl J Med 2016 11 24;375(20):1937-1945. Epub 2016 Oct 24.

From the Departments of Medicine (N.M.H., D.M.A., Y.L., R.B., M.A.C., P.J.D., J.H., T.E.W., J.W.E.), Pathology and Molecular Medicine (N.M.H., M.A.C., T.E.W., K.E.W.), and Clinical Epidemiology and Biostatistics (N.M.H., P.J.D.) and McMaster Centre for Transfusion Research (N.M.H., R.J.C., D.M.A., Y.L., R.B., T.E.W., K.E.W.), McMaster University, Canadian Blood Services (N.M.H., D.M.A., K.E.W.), the Population Health Research Institute (P.J.D., J.W.E.), and the Thrombosis and Atherosclerosis Research Institute (J.W.E.), Hamilton, ON, and the Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON (R.J.C.) - all in Canada; SA Pathology Transfusion Service, Flinders Medical Centre and Flinders University, Adelaide, SA, Australia (D.R., M.S.-T.); the Departments of General Anesthesiology (A.K.) and Outcomes Research (A.K., D.I.S.), Anesthesiology Institute, and the Robert J. Tomsich Pathology and Laboratory Medicine Institute and the Department of Laboratory Medicine (P.F.), Cleveland Clinic, Cleveland; and Meir Medical Center Kfar Saba and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel (M.E.).

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http://dx.doi.org/10.1056/NEJMoa1609014DOI Listing
November 2016

The Association of HLA-class I Genes and the Extent of Atherosclerotic Plaques in Patients with Psoriatic Disease.

J Rheumatol 2016 10 1;43(10):1844-1851. Epub 2016 Sep 1.

From the Women's College Research Institute, Women's College Hospital; the Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, and the Division of Dermatology, Toronto Western Hospital, Toronto, Ontario; and the Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.L. Eder, MD, PhD, Assistant Professor, Clinician Scientist, Women's College Hospital and Division of Rheumatology, Department of Medicine, University of Toronto; F. Abji, MSc, Laboratory Manager, Psoriatic Arthritis Program, Centre for Prognosis Studies in The Rheumatic Diseases, Toronto Western Hospital; C.F. Rosen, MD, Professor, Head of Division of Dermatology, Toronto Western Hospital and University Health Network, Department of Medicine, University of Toronto; V. Chandran, MD, DM, PhD, Assistant Professor, Co-director, Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, and Affiliate Scientist, Krembil Research Institute, and Division of Rheumatology, Department of Medicine, Department of Laboratory Medicine and Pathobiology, University of Toronto; R.J. Cook, PhD, Professor of Biostatistics, Department of Statistics and Actuarial Science, University of Waterloo; D.D. Gladman, MD, FRCPC, Professor of Medicine, University of Toronto, Senior Scientist, Krembil Research Institute, Director, Psoriatic Arthritis Program, Centre for Prognosis Studies in The Rheumatic Diseases, Toronto Western Hospital.

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http://dx.doi.org/10.3899/jrheum.151469DOI Listing
October 2016

Changing Pattern of Sputum Cell Counts During Successive Exacerbations of Chronic Obstructive Pulmonary Disease.

COPD 2015 11;12(6):628-35. Epub 2015 Aug 11.

a 1 Department of Medicine , St Joseph's Healthcare and McMaster University , Hamilton , Ontario , Canada.

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http://dx.doi.org/10.3109/15412555.2015.1057808DOI Listing
September 2016

Augmented composite likelihood for copula modeling in family studies under biased sampling.

Biostatistics 2016 07 27;17(3):437-52. Epub 2016 Jan 27.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada N2L 3G1.

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http://dx.doi.org/10.1093/biostatistics/kxv054DOI Listing
July 2016

Clinical and Demographic Characteristics of Erosion-free and Erosion-present Status in Psoriatic Arthritis in a Cohort Study.

J Rheumatol 2016 06 1;43(6):1057-62. Epub 2016 Apr 1.

From the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto; Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.Z. Touma, MD, FACP, FACR, PhD, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; A. Thavaneswaran, MMath, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; V. Chandran, MBBS, MD, DM, PhD, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; F. Pellett, BsC, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; R.J. Cook, PhD, Department of Statistics and Actuarial Science, University of Waterloo; D.D. Gladman, MD, FRCPC, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital.

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http://dx.doi.org/10.3899/jrheum.150466DOI Listing
June 2016

Red blood cell processing methods and in-hospital mortality: a transfusion registry cohort study.

Lancet Haematol 2016 May 4;3(5):e246-54. Epub 2016 Mar 4.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada.

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http://dx.doi.org/10.1016/S2352-3026(16)00020-XDOI Listing
May 2016

Sieve estimation in a Markov illness-death process under dual censoring.

Biostatistics 2016 Apr 22;17(2):350-63. Epub 2015 Nov 22.

Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, Waterloo, ON, Canada N2L 3G1.

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http://www-personal.umich.edu/~aboruvka/enar2014.pdf
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https://uwspace.uwaterloo.ca/bitstream/handle/10012/10528/Co
Web Search
http://biostatistics.oxfordjournals.org/lookup/doi/10.1093/b
Publisher Site
http://dx.doi.org/10.1093/biostatistics/kxv042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963425PMC
April 2016

Utilizing confocal laser endomicroscopy for evaluating the adequacy of laparoscopic liver ablation.

Lasers Surg Med 2016 Mar 31;48(3):299-310. Epub 2015 Dec 31.

Division of Surgery and Interventional Science, Royal Free Campus, University College London, Pond Street, NW3 2QG, London, UK.

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http://dx.doi.org/10.1002/lsm.22464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843950PMC
March 2016

The Incidence and Predictors of Infection in Psoriasis and Psoriatic Arthritis: Results from Longitudinal Observational Cohorts.

J Rheumatol 2016 Feb 15;43(2):362-6. Epub 2016 Jan 15.

From the Division of Rheumatology, Department of Medicine, University of Toronto; Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases; Toronto Western Hospital, University Health Network, Toronto; Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.A. Haddad, MD, Clinical Research Fellow, Division of Rheumatology, Department of Medicine, University of Toronto, and Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, and Toronto Western Hospital, University Health Network; S. Li, MMath, Biostatistician, Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, and Toronto Western Hospital, University Health Network; A. Thavaneswaran, MMath, Research Associate, Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, and Toronto Western Hospital, University Health Network; R.J. Cook, PhD, Professor, Canada Research Chair, Department of Statistics and Actuarial Science, University of Waterloo; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor, Department of Medicine, Division of Rheumatology, University of Toronto, and Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, and Toronto Western Hospital, University Health Network; D.D. Gladman, MD, FRCPC, Professor of Medicine, Department of Medicine, Division of Rheumatology, University of Toronto, and Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, and Toronto Western Hospital, University Health Network.

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http://dx.doi.org/10.3899/jrheum.140067DOI Listing
February 2016

Gene-Based Association Analysis for Censored Traits Via Fixed Effect Functional Regressions.

Genet Epidemiol 2016 Feb 18;40(2):133-43. Epub 2016 Jan 18.

Division of Pulmonary Medicine, Allergy and Immunology, Children's Hospital of Pittsburgh at The University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

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http://dx.doi.org/10.1002/gepi.21947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724326PMC
February 2016

Bias in progression-free survival analysis due to intermittent assessment of progression.

Stat Med 2015 Oct 24;34(24):3181-93. Epub 2015 May 24.

Department of Statistics and Actuarial Science, University of Waterloo, ON N2L 3G1, Waterloo, Canada.

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http://dx.doi.org/10.1002/sim.6529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744753PMC
October 2015

Does Cox analysis of a randomized survival study yield a causal treatment effect?

Lifetime Data Anal 2015 Oct 24;21(4):579-93. Epub 2015 Jun 24.

Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1007/s10985-015-9335-yDOI Listing
October 2015

Penalized regression for interval-censored times of disease progression: Selection of HLA markers in psoriatic arthritis.

Biometrics 2015 Sep 13;71(3):782-91. Epub 2015 Mar 13.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1.

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http://dx.doi.org/10.1111/biom.12302DOI Listing
September 2015

Adaptive sampling in two-phase designs: a biomarker study for progression in arthritis.

Stat Med 2015 Sep 7;34(21):2899-912. Epub 2015 May 7.

University of Waterloo, 200 University Avenue West, Waterloo, Ontario, N2L 3G1, Canada.

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http://dx.doi.org/10.1002/sim.6523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691319PMC
September 2015

Analysis of interval-censored recurrent event processes subject to resolution.

Biom J 2015 Sep 7;57(5):725-42. Epub 2015 Jul 7.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1002/bimj.201400162DOI Listing
September 2015

Warfarin-induced venous limb ischemia/gangrene complicating cancer: a novel and clinically distinct syndrome.

Blood 2015 Jul 15;126(4):486-93. Epub 2015 May 15.

Department of Pathology and Molecular Medicine, and Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada;

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2015-01-62
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http://dx.doi.org/10.1182/blood-2015-01-622787DOI Listing
July 2015

Thrombotic events in metastatic colorectal cancer patients treated with leucovorin, fluorouracil and irinotican (FOLFIRI) plus bevacizumab.

J Gastrointest Oncol 2015 Jun;6(3):274-9

1 Department of Oncology, McMaster University, Hamilton, Ontario, Canada ; 2 Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada ; 3 Department of Medicine, Sheikh Zayed Military Hospital, Abu Dhabi, United Arab Emirates ; 4 Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.3978/j.issn.2078-6891.2015.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397249PMC
June 2015

Obesity is associated with a lower probability of achieving sustained minimal disease activity state among patients with psoriatic arthritis.

Ann Rheum Dis 2015 May 15;74(5):813-7. Epub 2014 Jan 15.

University of Toronto Psoriatic Arthritis Clinic, Centre for Prognosis Studies in the Rheumatic Diseases-Toronto Western Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/annrheumdis-2013-204448DOI Listing
May 2015

Minimal disease activity and anti-tumor necrosis factor therapy in psoriatic arthritis.

Arthritis Care Res (Hoboken) 2015 May;67(6):842-7

University of Toronto Psoriatic Arthritis Program and Toronto Western Hospital, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/acr.22529
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May 2015

Sample size and robust marginal methods for cluster-randomized trials with censored event times.

Stat Med 2015 Mar 17;34(6):901-23. Epub 2014 Dec 17.

Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, Waterloo, N2L 3G1, ON, Canada.

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http://dx.doi.org/10.1002/sim.6395DOI Listing
March 2015

Exploratory studies on the age of transfused blood and in-hospital mortality in patients with cardiovascular diagnoses.

Transfusion 2015 Feb 19;55(2):364-72. Epub 2014 Sep 19.

Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada; Centre for Innovation, Canadian Blood Services, Hamilton, Ontario, Canada.

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http://doi.wiley.com/10.1111/trf.12861
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February 2015

Composite likelihood for joint analysis of multiple multistate processes via copulas.

Biostatistics 2014 Oct 9;15(4):690-705. Epub 2014 Apr 9.

Department of Statistics and Actuarial Science,University of Waterloo,Waterloo, ON, N2L 3G1, Canada.

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http://dx.doi.org/10.1093/biostatistics/kxu011DOI Listing
October 2014

External validation of a risk assessment model for venous thromboembolism in the hospitalised acutely-ill medical patient (VTE-VALOURR).

Thromb Haemost 2014 Oct 3;112(4):692-9. Epub 2014 Jul 3.

Alex C Spyropoulos, MD, FACP, FCCP, FRCPC, Director - Anticoagulation Services and Clinical Thrombosis, North Shore-LIJ Health System at Lenox Hill Hospital, Professor of Medicine, Hofstra North Shore-LIJ School of Medicine, Manhasset, New York, USA, Tel.: +1 212 434 6776, Fax: +1 212 434 6781, E-mail:

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http://dx.doi.org/10.1160/TH14-03-0239DOI Listing
October 2014

Reliability of radiographic scoring methods in axial psoriatic arthritis.

Arthritis Care Res (Hoboken) 2014 Sep;66(9):1417-22

Toronto Western Hospital, Toronto, Ontario, Canada, and University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/acr.22308DOI Listing
September 2014

A dynamic Mover-Stayer model for recurrent event processes subject to resolution.

Lifetime Data Anal 2014 Jul 20;20(3):404-23. Epub 2013 Jun 20.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, N2L 3G1, Canada,

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http://dx.doi.org/10.1007/s10985-013-9271-7DOI Listing
July 2014

Kidney function after off-pump or on-pump coronary artery bypass graft surgery: a randomized clinical trial.

JAMA 2014 Jun;311(21):2191-8

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada4Population Health Research Institute, Hamilton, Ontario, Canada16Division of Cardiac Surgery, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1001/jama.2014.4952DOI Listing
June 2014

Incomplete data in randomized dermatology trials: consequences and statistical methodology.

Dermatology 2013 23;226(1):19-27. Epub 2013 Feb 23.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ont., Canada.

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http://dx.doi.org/10.1159/000346247DOI Listing
January 2014

Present and future of glass-ionomers and calcium-silicate cements as bioactive materials in dentistry: biophotonics-based interfacial analyses in health and disease.

Dent Mater 2014 Jan 7;30(1):50-61. Epub 2013 Oct 7.

King's College London Dental Institute, Biomaterials, Biomimetics & Biophotonics (B(3)), Floor 17, Guy's Tower Wing, Guy's Hospital, London Bridge SE1 9RT, United Kingdom.

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http://dx.doi.org/10.1016/j.dental.2013.08.202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885799PMC
January 2014

Inverse probability weighted estimating equations for randomized trials in transfusion medicine.

Stat Med 2013 Nov 28;32(25):4380-99. Epub 2013 Apr 28.

Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, Waterloo, ON, Canada N2L 3G1.

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http://dx.doi.org/10.1002/sim.5827DOI Listing
November 2013

A copula model for marked point processes.

Lifetime Data Anal 2013 Oct 10;19(4):463-89. Epub 2013 May 10.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, N2L 3G1, Canada,

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http://dx.doi.org/10.1007/s10985-013-9259-3DOI Listing
October 2013

Authors' redress on 'robustness of methods for blinded sample size re-estimation with overdispersed count data'.

Authors:
Richard J Cook

Stat Med 2013 Sep;32(22):3955-7

Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, Waterloo, ON, Canada, N2L 3G1.

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http://dx.doi.org/10.1002/sim.5983DOI Listing
September 2013

Clinical trials evaluating pathogen-reduced platelet products: methodologic issues and recommendations.

Transfusion 2013 Aug 12;53(8):1843-55. Epub 2012 Nov 12.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1537-2995.2012.03951.xDOI Listing
August 2013

Rehabilitation in home care is associated with functional improvement and preferred discharge.

Arch Phys Med Rehabil 2013 Jun 4;94(6):1038-47. Epub 2013 Feb 4.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1016/j.apmr.2012.12.024DOI Listing
June 2013

Soluble biomarkers associated with response to treatment with tumor necrosis factor inhibitors in psoriatic arthritis.

J Rheumatol 2013 Jun 1;40(6):866-71. Epub 2013 May 1.

Department of Medicine, Division of Rheumatology, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.3899/jrheum.121162DOI Listing
June 2013

Regression with incomplete covariates and left-truncated time-to-event data.

Stat Med 2013 Mar 28;32(6):1004-15. Epub 2012 Aug 28.

Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, Waterloo, ON, Canada, N2L 3G1.

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http://dx.doi.org/10.1002/sim.5581DOI Listing
March 2013

A blinded study of bone marrow examinations in patients with primary immune thrombocytopenia.

Eur J Haematol 2013 Feb 13;90(2):121-6. Epub 2012 Dec 13.

Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1111/ejh.12041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938453PMC
February 2013

Misspecification of Cox regression models with composite endpoints.

Stat Med 2012 Dec 27;31(28):3545-62. Epub 2012 Jun 27.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada.

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http://dx.doi.org/10.1002/sim.5436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575694PMC
December 2012

Serum lactate dehydrogenase is prognostic for survival in patients with bone metastases from breast cancer: a retrospective analysis in bisphosphonate-treated patients.

Clin Cancer Res 2012 Nov 4;18(22):6348-55. Epub 2012 Sep 4.

Cancer Research UK Experimental Cancer Medicine Centres at Leeds and Sheffield, Cancer Research Centre, Academic Unit of Clinical Oncology, Weston Park Hospital, Sheffield, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-1397DOI Listing
November 2012

Marginal methods for clustered longitudinal binary data with incomplete covariates.

J Stat Plan Inference 2012 Oct;142(10):2819-2831

Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE 68198, USA.

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http://dx.doi.org/10.1016/j.jspi.2012.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690662PMC
October 2012

Acute hepatic necrosis and ischemic limb necrosis.

N Engl J Med 2012 Aug;367(9):879-81

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http://dx.doi.org/10.1056/NEJMc1207074DOI Listing
August 2012

The effect of blood storage duration on in-hospital mortality: a randomized controlled pilot feasibility trial.

Transfusion 2012 Jun 18;52(6):1203-12. Epub 2012 Jan 18.

Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1537-2995.2011.03521.xDOI Listing
June 2012

The association between smoking and the development of psoriatic arthritis among psoriasis patients.

Ann Rheum Dis 2012 Feb 27;71(2):219-24. Epub 2011 Sep 27.

Psoriatic Arthritis Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University of Toronto, ON, Canada.

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http://dx.doi.org/10.1136/ard.2010.147793DOI Listing
February 2012

Re-localisation of a biopsy site in endoscopic images and characterisation of its uncertainty.

Med Image Anal 2012 Feb 2;16(2):482-96. Epub 2011 Dec 2.

Centre for Medical Image Computing, University College London, Gower Street, London, UK.

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http://dx.doi.org/10.1016/j.media.2011.11.005DOI Listing
February 2012

Causal inference in nonrandomized studies via propensity score methods.

Transfusion 2011 Dec 2;51(12):2536-9. Epub 2011 Sep 2.

Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1537-2995.2011.03324.xDOI Listing
December 2011

Do patients with psoriatic arthritis who present early fare better than those presenting later in the disease?

Ann Rheum Dis 2011 Dec 12;70(12):2152-4. Epub 2011 Sep 12.

Department of Medicine, University of Toronto, Ontario, Canada.

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http://ard.bmj.com/cgi/doi/10.1136/ard.2011.150938
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December 2011

Effect of pregnancy on ankylosing spondylitis: a case-control study.

J Rheumatol 2011 Nov 15;38(11):2442-4. Epub 2011 Aug 15.

Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, Canada.

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http://dx.doi.org/10.3899/jrheum.101174DOI Listing
November 2011

Seasonal variation in vitamin D levels in psoriatic arthritis patients from different latitudes and its association with clinical outcomes.

Arthritis Care Res (Hoboken) 2011 Oct;63(10):1440-7

Centre for Prognosis Studiesin the Rheumatic Diseases, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/acr.20530DOI Listing
October 2011

Clinical correlates of urolithiasis in ankylosing spondylitis.

J Rheumatol 2011 Sep 1;38(9):1953-6. Epub 2011 Jun 1.

1E-423, Toronto Western Hospital, 399 Bathurst St., Toronto, Ontario M5T 2S8, Canada.

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http://www.jrheum.org/cgi/doi/10.3899/jrheum.101175
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http://dx.doi.org/10.3899/jrheum.101175DOI Listing
September 2011

Association between environmental factors and onset of psoriatic arthritis in patients with psoriasis.

Arthritis Care Res (Hoboken) 2011 Aug;63(8):1091-7

Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/acr.20496DOI Listing
August 2011

The Spondyloarthritis Research Consortium of Canada registry for spondyloarthritis.

J Rheumatol 2011 Jul 15;38(7):1343-8. Epub 2011 Apr 15.

Toronto Western Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.101102DOI Listing
July 2011