Richard Iggo

Richard Iggo

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Richard Iggo

Richard Iggo

Publications by authors named "Richard Iggo"

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The ninth ENBDC Weggis meeting: growth and in-depth characterisation of normal and neoplastic breast cells.

Breast Cancer Res 2017 Aug 22;19(1):96. Epub 2017 Aug 22.

INSERM U1218, Institut Bergonie, University of Bordeaux, 229 cours de l'Argonne, 33076, Bordeaux, France.

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http://breast-cancer-research.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/s13058-017-0891-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568390PMC
August 2017

MICADo - Looking for Mutations in Targeted PacBio Cancer Data: An Alignment-Free Method.

Front Genet 2016 8;7:214. Epub 2016 Dec 8.

Centre de BioInformatique de Bordeaux, University of BordeauxBordeaux, France; Laboratoire Bordelais de Recherche en Informatique, Centre National de la Recherche Scientifique, University of BordeauxBordeaux, France.

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http://dx.doi.org/10.3389/fgene.2016.00214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143680PMC
December 2016

The mammary ducts create a favourable microenvironment for xenografting of luminal and molecular apocrine breast tumours.

J Pathol 2016 11 29;240(3):256-261. Epub 2016 Sep 29.

INSERM U1218, Bergonie Cancer Institute, University of Bordeaux, 33076, Bordeaux, France.

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http://dx.doi.org/10.1002/path.4772DOI Listing
November 2016

Cluster Analysis of p53 Binding Site Sequences Reveals Subsets with Different Functions.

Cancer Inform 2016 25;15:199-209. Epub 2016 Oct 25.

School of Biology, University of St Andrews, St Andrews, UK.; Current address: Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.4137/CIN.S39968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081245PMC
October 2016

Lentiviral transduction of mammary epithelial cells.

Methods Mol Biol 2015 ;1293:137-60

Bergonié Cancer Institute, University of Bordeaux, 229 cours de l'Argonne, 33076, Bordeaux, France,

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http://dx.doi.org/10.1007/978-1-4939-2519-3_8DOI Listing
February 2016

Disequilibrium of BMP2 levels in the breast stem cell niche launches epithelial transformation by overamplifying BMPR1B cell response.

Stem Cell Reports 2015 Feb 15;4(2):239-54. Epub 2015 Jan 15.

CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, 69000 Lyon, France; Inserm U1052, Centre de Recherche en Cancérologie de Lyon, 69000 Lyon, France; Université de Lyon, 69000 Lyon, France; Department of Immunity, Virus, and Microenvironment, 69000 Lyon, France; Université de Lyon 1, ISPB, 69000 Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2014.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325271PMC
February 2015

Validation of a yeast functional assay for p53 mutations using clonal sequencing.

J Pathol 2013 Dec;231(4):441-8

INSERM U916, Institut Bergonié Comprehensive Cancer Centre, Univ. Bordeaux, F-33000, Bordeaux, France.

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http://dx.doi.org/10.1002/path.4243DOI Listing
December 2013

Models incorporating chromatin modification data identify functionally important p53 binding sites.

Nucleic Acids Res 2013 Jun 17;41(11):5582-93. Epub 2013 Apr 17.

Sir Harold Mitchell Building, School of Biology, University of St Andrews, St Andrews, Fife, KY16 9TH, UK.

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http://dx.doi.org/10.1093/nar/gkt260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675478PMC
June 2013

New insights into the role of androgen and oestrogen receptors in molecular apocrine breast tumours.

Authors:
Richard D Iggo

Breast Cancer Res 2011 8;13(6):318. Epub 2011 Dec 8.

INSERM U916, Bergonie Cancer Institute, University of Bordeaux, 229 cours de l'Argonne, 33076 Bordeaux, France.

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http://dx.doi.org/10.1186/bcr3036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326548PMC
June 2012

Targeted radionuclide therapy using a Wnt-targeted replicating adenovirus encoding the Na/I symporter.

Clin Cancer Res 2009 Nov 27;15(21):6595-601. Epub 2009 Oct 27.

Centre for Molecular Oncology, Institute of Cancer, Queen Mary's School of Medicine and Dentistry, London, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0262DOI Listing
November 2009

Predictive signatures for chemotherapy sensitivity in breast cancer: are they ready for use in the clinic?

Eur J Cancer 2009 Jul 26;45(10):1733-43. Epub 2009 May 26.

Bergonié Cancer Institute and University of Bordeaux, Bordeaux Cedex, France.

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http://linkinghub.elsevier.com/retrieve/pii/S095980490900335
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http://dx.doi.org/10.1016/j.ejca.2009.04.036DOI Listing
July 2009

p53 Mutation in histologically normal mucosa of the aero-digestive tract is not a marker of increased risk for second primary carcinoma in head and neck cancer patients.

Eur Arch Otorhinolaryngol 2009 Apr 8;266(4):547-51. Epub 2008 Aug 8.

Department of Otolaryngology and Head and Neck Surgery, University Hospital, Centre Universitaire Hospitalier Vaudois, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s00405-008-0780-zDOI Listing
April 2009

A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer.

Nat Med 2009 Jan 4;15(1):68-74. Epub 2009 Jan 4.

Swiss National Centre of Competence in Research Molecular Oncology, Swiss Institute for Experimental Cancer Research, Ecole Polytechnique Fédérale de Lausanne, School of Life Sciences, Epalinges s/Lausanne, Switzerland.

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http://dx.doi.org/10.1038/nm.1908DOI Listing
January 2009

Therapeutic potential of replication-selective oncolytic adenoviruses on cells from familial and sporadic desmoid tumors.

Clin Cancer Res 2008 Oct;14(19):6187-92

Institute of Cancer and the CR-UK Clinical Centre, Barts and The London, Queen Mary's School of Medicine and Dentistry, London, United Kingdom.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-08-0410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575844PMC
October 2008

Evidence of frequent recombination among human adenoviruses.

J Gen Virol 2008 Feb;89(Pt 2):380-8

Bute Medical School, University of St Andrews, Scotland, UK.

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http://dx.doi.org/10.1099/vir.0.83057-0DOI Listing
February 2008

Expression of heterologous genes in oncolytic adenoviruses using picornaviral 2A sequences that trigger ribosome skipping.

J Gen Virol 2008 Feb;89(Pt 2):389-96

School of Medicine, Biomolecular Sciences Building, University of St Andrews, St Andrews KY16 9ST, UK.

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http://dx.doi.org/10.1099/vir.0.83444-0DOI Listing
February 2008

An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells.

Breast Cancer Res 2007 ;9(3):R38

NCCR Molecular Oncology, Swiss Institute for Experimental Cancer Research (ISREC), Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1186/bcr1734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929103PMC
September 2007

Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays.

Cancer Res 2007 May;67(10):4595-604

Department of Clinical Oncology, Institute of Development, Aging and Cancer, Tohoku University Hospital, Tohoku University, Sendai, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3509DOI Listing
May 2007

Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells.

BMC Cancer 2006 Oct 4;6:236. Epub 2006 Oct 4.

NCCR Molecular Oncology Programme, Swiss Institute for Experimental Cancer Research (ISREC), Epalinges, Switzerland.

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http://dx.doi.org/10.1186/1471-2407-6-236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609183PMC
October 2006

Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954.

Hum Gene Ther 2005 Dec;16(12):1473-83

NCCR Molecular Oncology Program, Swiss Institute for Experimental Cancer Research (ISREC), Epalinges CH-1066, Switzerland.

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http://documents.epfl.ch/users/c/cf/cfuerer/www/papers/2005_
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http://www.liebertonline.com/doi/abs/10.1089/hum.2005.16.147
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http://dx.doi.org/10.1089/hum.2005.16.1473DOI Listing
December 2005

RAD001 (everolimus) improves the efficacy of replicating adenoviruses that target colon cancer.

Cancer Res 2005 Aug;65(15):6882-90

National Center of Competence in Research Molecular Oncology, Swiss Institute for Experimental Cancer Research (ISREC), Epalinges, Switzerland.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-0309DOI Listing
August 2005

Promoter-specific p53-dependent histone acetylation following DNA damage.

Oncogene 2004 May;23(22):4007-13

Oncogene Group, Swiss Institute for Experimental Cancer Research (ISREC), ch. des Boveresses 155, 1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1038/sj.onc.1207536DOI Listing
May 2004

Determinants of interferon-stimulated gene induction by RNAi vectors.

Differentiation 2004 Mar;72(2-3):103-11

Oncogene Group, Swiss Institute for Experimental Cancer Research (ISREC), Ch. des Boveresses, 1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1111/j.1432-0436.2004.07202001.xDOI Listing
March 2004

Regulation of p53 stability and function in HCT116 colon cancer cells.

J Biol Chem 2004 Feb 9;279(9):7598-605. Epub 2003 Dec 9.

Oncogene Group, Swiss Institute for Experimental Cancer Research, Ch des Boveresses 155, 1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1074/jbc.M311732200DOI Listing
February 2004

Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses.

J Biol Chem 2003 Oct 8;278(42):41028-33. Epub 2003 Aug 8.

Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093-0322, USA.

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http://dx.doi.org/10.1074/jbc.M306938200DOI Listing
October 2003

Protection from HIV-1 infection of primary CD4 T cells by CCR5 silencing is effective for the full spectrum of CCR5 expression.

Antivir Ther 2003 Oct;8(5):373-7

Infectious Diseases and Institute of Microbiology, Centre Hospitalier Universitaire Vaudois, CHUV, Lausanne, Switzerland.

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October 2003

Induction of an interferon response by RNAi vectors in mammalian cells.

Nat Genet 2003 Jul;34(3):263-4

Swiss Institute for Experimental Cancer Research, CH-1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1038/ng1173DOI Listing
July 2003