Richard Houghton

Richard Houghton

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Richard Houghton

Richard Houghton

Publications by authors named "Richard Houghton"

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Fumarate Metabolic Signature for the Detection of Reed Syndrome in Humans.

Clin Cancer Res 2020 Jan 21;26(2):391-396. Epub 2019 Oct 21.

Department of Medical Genetics, University of Cambridge and NIHR Cambridge Biomedical Research Centre and Cancer Research UK Cambridge Centre, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-1729DOI Listing
January 2020

Psychostimulants/Atomoxetine and Serious Cardiovascular Events in Children with ADHD or Autism Spectrum Disorder.

CNS Drugs 2020 Jan;34(1):93-101

Personalized Health Care Data Science, Real World Data, F. Hoffmann-La Roche Ltd., Grenzacherstrasse. 124, 4070, Basel, Switzerland.

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http://dx.doi.org/10.1007/s40263-019-00686-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982643PMC
January 2020

Psychometric Validation of the Autism Impact Measure (AIM).

J Autism Dev Disord 2019 Jun;49(6):2559-2570

Patient Centered Outcomes Research, Biometrics, Roche Products, Ltd, Falcon Way, Welwyn Garden City, UK.

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http://link.springer.com/10.1007/s10803-019-04011-2
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http://dx.doi.org/10.1007/s10803-019-04011-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546866PMC
June 2019

Correction to: Psychometric Validation of the Autism Impact Measure (AIM).

J Autism Dev Disord 2019 Jun;49(6):2571

Patient Centered Outcomes Research, Biometrics, Roche Products, Ltd, Falcon Way, Welwyn Garden City, UK.

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http://link.springer.com/10.1007/s10803-019-04076-z
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http://dx.doi.org/10.1007/s10803-019-04076-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546867PMC
June 2019

Treatment patterns in children with autism in the United States.

Autism Res 2019 03 10;12(3):517-526. Epub 2019 Jan 10.

Personalized Health Care Data Science, Real World Data, F. Hoffmann-La Roche Ltd., Basel, Switzerland.

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http://doi.wiley.com/10.1002/aur.2070
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http://dx.doi.org/10.1002/aur.2070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519302PMC
March 2019

Treatment Patterns in Patients with Incident Parkinson's Disease in the United States.

J Parkinsons Dis 2019 ;9(4):749-759

Product Development Personalized Health Care, F. Hoffmann-La Roche Ltd., Basel, Switzerland.

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http://dx.doi.org/10.3233/JPD-191636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839607PMC
January 2019

Psychiatric Comorbidities and Psychotropic Medication Use in Autism: A Matched Cohort Study with ADHD and General Population Comparator Groups in the United Kingdom.

Autism Res 2018 12 31;11(12):1690-1700. Epub 2018 Oct 31.

Neuroscience, Ophthalmology, and Rare Diseases (NORD), Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche, Ltd., Basel, Switzerland.

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http://dx.doi.org/10.1002/aur.2040DOI Listing
December 2018

Tacrolimus-Induced Cholestatic Hepatitis in a Patient With Liver Transplant.

Transplantation 2018 10;102(10):e454-e456

PHE MD SAMU-Asturias, Oviedo, Spain.

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http://dx.doi.org/10.1097/TP.0000000000002332DOI Listing
October 2018

Where is the residual terrestrial carbon sink?

Glob Chang Biol 2018 08 7;24(8):3277-3279. Epub 2018 Jun 7.

Woods Hole Research Center, Falmouth, Massachusetts, USA.

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http://dx.doi.org/10.1111/gcb.14313DOI Listing
August 2018

Negative emissions from stopping deforestation and forest degradation, globally.

Glob Chang Biol 2018 01 22;24(1):350-359. Epub 2017 Sep 22.

Woods Hole Research Center, Falmouth, MA, USA.

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http://dx.doi.org/10.1111/gcb.13876DOI Listing
January 2018

Psychiatric comorbidities and use of psychotropic medications in people with autism spectrum disorder in the United States.

Autism Res 2017 Dec 30;10(12):2037-2047. Epub 2017 Sep 30.

Neuroscience, Ophthalmology, and Rare Diseases (NORD), Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, Basel, 4070, Switzerland.

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http://dx.doi.org/10.1002/aur.1848DOI Listing
December 2017

Fire and deforestation dynamics in Amazonia (1973-2014).

Global Biogeochem Cycles 2017 Jan 12;31(1):24-38. Epub 2017 Jan 12.

NASA Goddard Institute for Space StudiesNew YorkNew YorkUSA; Center for Climate Systems ResearchColumbia UniversityNew YorkNew YorkUSA.

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http://dx.doi.org/10.1002/2016GB005445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324547PMC
January 2017

Determination of avibactam and ceftazidime in human plasma samples by LC-MS.

Bioanalysis 2015 ;7(12):1423-34

AstraZeneca, Macclesfield, Cheshire East SK10 2NA, UK.

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http://dx.doi.org/10.4155/bio.15.76DOI Listing
April 2016

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

Authors:
Martin Hrabě de Angelis George Nicholson Mohammed Selloum Jacqui White Hugh Morgan Ramiro Ramirez-Solis Tania Sorg Sara Wells Helmut Fuchs Martin Fray David J Adams Niels C Adams Thure Adler Antonio Aguilar-Pimentel Dalila Ali-Hadji Gregory Amann Philippe André Sarah Atkins Aurelie Auburtin Abdel Ayadi Julien Becker Lore Becker Elodie Bedu Raffi Bekeredjian Marie-Christine Birling Andrew Blake Joanna Bottomley Mike Bowl Véronique Brault Dirk H Busch James N Bussell Julia Calzada-Wack Heather Cater Marie-France Champy Philippe Charles Claire Chevalier Francesco Chiani Gemma F Codner Roy Combe Roger Cox Emilie Dalloneau André Dierich Armida Di Fenza Brendan Doe Arnaud Duchon Oliver Eickelberg Chris T Esapa Lahcen El Fertak Tanja Feigel Irina Emelyanova Jeanne Estabel Jack Favor Ann Flenniken Alessia Gambadoro Lilian Garrett Hilary Gates Anna-Karin Gerdin George Gkoutos Simon Greenaway Lisa Glasl Patrice Goetz Isabelle Goncalves Da Cruz Alexander Götz Jochen Graw Alain Guimond Wolfgang Hans Geoff Hicks Sabine M Hölter Heinz Höfler John M Hancock Robert Hoehndorf Tertius Hough Richard Houghton Anja Hurt Boris Ivandic Hughes Jacobs Sylvie Jacquot Nora Jones Natasha A Karp Hugo A Katus Sharon Kitchen Tanja Klein-Rodewald Martin Klingenspor Thomas Klopstock Valerie Lalanne Sophie Leblanc Christoph Lengger Elise le Marchand Tonia Ludwig Aline Lux Colin McKerlie Holger Maier Jean-Louis Mandel Susan Marschall Manuel Mark David G Melvin Hamid Meziane Kateryna Micklich Christophe Mittelhauser Laurent Monassier David Moulaert Stéphanie Muller Beatrix Naton Frauke Neff Patrick M Nolan Lauryl Mj Nutter Markus Ollert Guillaume Pavlovic Natalia S Pellegata Emilie Peter Benoit Petit-Demoulière Amanda Pickard Christine Podrini Paul Potter Laurent Pouilly Oliver Puk David Richardson Stephane Rousseau Leticia Quintanilla-Fend Mohamed M Quwailid Ildiko Racz Birgit Rathkolb Fabrice Riet Janet Rossant Michel Roux Jan Rozman Ed Ryder Jennifer Salisbury Luis Santos Karl-Heinz Schäble Evelyn Schiller Anja Schrewe Holger Schulz Ralf Steinkamp Michelle Simon Michelle Stewart Claudia Stöger Tobias Stöger Minxuan Sun David Sunter Lydia Teboul Isabelle Tilly Glauco P Tocchini-Valentini Monica Tost Irina Treise Laurent Vasseur Emilie Velot Daniela Vogt-Weisenhorn Christelle Wagner Alison Walling Bruno Weber Olivia Wendling Henrik Westerberg Monja Willershäuser Eckhard Wolf Anne Wolter Joe Wood Wolfgang Wurst Ali Önder Yildirim Ramona Zeh Andreas Zimmer Annemarie Zimprich Chris Holmes Karen P Steel Yann Herault Valérie Gailus-Durner Ann-Marie Mallon Steve Dm Brown

Nat Genet 2015 Sep 27;47(9):969-978. Epub 2015 Jul 27.

MRC Harwell, Medical Research Council, Harwell, UK.

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http://dx.doi.org/10.1038/ng.3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564951PMC
September 2015

Evidence for environmentally enhanced forest growth.

Proc Natl Acad Sci U S A 2014 Jul 16;111(26):9527-32. Epub 2014 Jun 16.

Woods Hole Research Center, Falmouth, MA 02540.

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http://dx.doi.org/10.1073/pnas.1402333111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084460PMC
July 2014

The 20th International Reid Bioanalytical Forum.

Authors:
Richard Houghton

Bioanalysis 2014 Jan;6(2):121-6

Quotient Bio Analytical Sciences, Newmarket Road, Fordham, Cambridge, CB7 5WW, UK.

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http://dx.doi.org/10.4155/bio.13.312DOI Listing
January 2014

Keeping management effects separate from environmental effects in terrestrial carbon accounting.

Glob Chang Biol 2013 Sep 15;19(9):2609-12. Epub 2013 Jul 15.

Woods Hole Research Center, Falmouth, MA 02540, USA.

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http://dx.doi.org/10.1111/gcb.12233DOI Listing
September 2013

Joint CO2 and CH4 accountability for global warming.

Proc Natl Acad Sci U S A 2013 Jul 11;110(31):E2865-74. Epub 2013 Jul 11.

Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA 94720-7360, USA.

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http://dx.doi.org/10.1073/pnas.1308004110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732991PMC
July 2013

Large-scale mouse knockouts and phenotypes.

Wiley Interdiscip Rev Syst Biol Med 2012 Nov-Dec;4(6):547-63. Epub 2012 Aug 15.

Mouse Pipelines, Wellcome Trust Sanger Institute, Hinxton, UK.

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http://dx.doi.org/10.1002/wsbm.1183DOI Listing
February 2013

The mammalian gene function resource: the International Knockout Mouse Consortium.

Mamm Genome 2012 Oct 12;23(9-10):580-6. Epub 2012 Sep 12.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1007/s00335-012-9422-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463800PMC
October 2012

Recommendations on bioanalytical method stability implications of co-administered and co-formulated drugs by Global CRO Council for Bioanalysis (GCC).

Bioanalysis 2012 Sep;4(17):2117-26

Advion Bioanalytical Laboratories, Quintiles, NY, USA.

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http://dx.doi.org/10.4155/bio.12.192DOI Listing
September 2012

Efficacy of plasma phospholipid removal during sample preparation and subsequent retention under typical UHPLC conditions.

Bioanalysis 2012 Apr;4(7):795-807

Quotient Bioresearch, Fordham, Ely, CB7 5WW, UK.

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http://dx.doi.org/10.4155/bio.12.38DOI Listing
April 2012

Conference Report: Analytical challenges in the qualification and validation of pharmacodynamic biomarkers.

Bioanalysis 2011 May;3(9):945-8

Quotient Bioresearch Ltd., Newmarket Road, Fordham, Cambridge, UK.

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http://dx.doi.org/10.4155/bio.11.90DOI Listing
May 2011

Implications of land use change on the national terrestrial carbon budget of Georgia.

Carbon Balance Manag 2010 Sep 13;5. Epub 2010 Sep 13.

Department of Geography and Environment, Boston University, 675 Commonwealth Avenue, Boston, MA 02215, USA.

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http://dx.doi.org/10.1186/1750-0680-5-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945338PMC
September 2010

Generic approach to validation of small-molecule LC-MS/MS biomarker assays.

Bioanalysis 2009 Nov;1(8):1365-74

Quotient Bioresearch Ltd, Newmarket Road, Fordham, Cambridge CB75WW, UK.

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http://dx.doi.org/10.4155/bio.09.139DOI Listing
November 2009

Dissociation of pathological and molecular phenotype of variant Creutzfeldt-Jakob disease in transgenic human prion protein 129 heterozygous mice.

Proc Natl Acad Sci U S A 2006 Jul 29;103(28):10759-64. Epub 2006 Jun 29.

Medical Research Council Prion Unit and Department of Neurodegenerative Disease, Institute of Neurology, University College London, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, United Kingdom.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0604292103
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http://dx.doi.org/10.1073/pnas.0604292103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502304PMC
July 2006

Carbon emissions from tropical deforestation and regrowth based on satellite observations for the 1980s and 1990s.

Proc Natl Acad Sci U S A 2002 Oct 16;99(22):14256-61. Epub 2002 Oct 16.

Department of Geography and Earth System Science Interdisciplinary Center, University of Maryland, College Park, MD 20742, USA.

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http://www.pnas.org/content/99/22/14256.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.182560099
Publisher Site
http://dx.doi.org/10.1073/pnas.182560099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137871PMC
October 2002

Terrestrial carbon sinks--uncertain explanations.

Biologist (London) 2002 Aug;49(4):155-60

Woods Hole Research Center, PO Box 296, Woods Hole, MA 02543, USA.

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August 2002