Publications by authors named "Richard Helm"

64Publications

Cellular Stoichiometry of Chemotaxis Proteins in .

J Bacteriol 2020 Jun 25;202(14). Epub 2020 Jun 25.

Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA

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http://dx.doi.org/10.1128/JB.00141-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317046PMC
June 2020

The dynamic response of the Arabidopsis root metabolome to auxin and ethylene is not predicted by changes in the transcriptome.

Sci Rep 2020 01 20;10(1):679. Epub 2020 Jan 20.

Department of Biological Sciences, Virginia Tech, Blacksburg, VA, United States of America.

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http://dx.doi.org/10.1038/s41598-019-57161-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971091PMC
January 2020

Functional annotation of serine hydrolases in the asexual erythrocytic stage of Plasmodium falciparum.

Sci Rep 2019 11 26;9(1):17532. Epub 2019 Nov 26.

Department of Biochemistry, Virginia Tech, Blacksburg, VA, 24061, USA.

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http://dx.doi.org/10.1038/s41598-019-54009-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879560PMC
November 2019

Cortisol is the predominant glucocorticoid in the giant paedomorphic hellbender salamander (Cryptobranchus alleganiensis).

Gen Comp Endocrinol 2020 01 3;285:113267. Epub 2019 Sep 3.

Dept of Biology, Tufts University, Medford, MA 02144, USA.

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http://dx.doi.org/10.1016/j.ygcen.2019.113267DOI Listing
January 2020

Membrane Proteomes and Ion Transporters in and Dormant and Germinating Spores.

J Bacteriol 2019 03 25;201(6). Epub 2019 Feb 25.

Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA

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http://dx.doi.org/10.1128/JB.00662-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398275PMC
March 2019

Identification of MOS9 as an interaction partner for chalcone synthase in the nucleus.

PeerJ 2018 19;6:e5598. Epub 2018 Sep 19.

Department of Biological Sciences, Virginia Polytechnic Institute and State University (Virginia Tech), Blacksburg, VA, USA.

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http://dx.doi.org/10.7717/peerj.5598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151112PMC
September 2018

Sinorhizobium meliloti Chemoreceptor McpV Senses Short-Chain Carboxylates via Direct Binding.

J Bacteriol 2018 12 6;200(23). Epub 2018 Nov 6.

Virginia Tech, Department of Biological Sciences, Blacksburg, Virginia, USA

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http://jb.asm.org/lookup/doi/10.1128/JB.00519-18
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http://dx.doi.org/10.1128/JB.00519-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222202PMC
December 2018

More than Rotating Flagella: Lipopolysaccharide as a Secondary Receptor for Flagellotropic Phage 7-7-1.

J Bacteriol 2018 10 10;200(19). Epub 2018 Sep 10.

Department of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA

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http://dx.doi.org/10.1128/JB.00363-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148473PMC
October 2018

Evaluation of Feruloylated and p-Coumaroylated Arabinosyl Units in Grass Arabinoxylans by Acidolysis in Dioxane/Methanol.

J Agric Food Chem 2018 May 18;66(21):5418-5424. Epub 2018 May 18.

Department of Biochemistry, and The Department of Energy's Great Lakes Bioenergy Research Center, The Wisconsin Energy Institute , University of Wisconsin , Madison , Wisconsin 53726 , United States.

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http://pubs.acs.org/doi/10.1021/acs.jafc.8b01618
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http://dx.doi.org/10.1021/acs.jafc.8b01618DOI Listing
May 2018

Characterization of the adult Aedes aegypti early midgut peritrophic matrix proteome using LC-MS.

PLoS One 2018 23;13(3):e0194734. Epub 2018 Mar 23.

Department of Entomology, Texas A&M University, College Station, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194734PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865745PMC
July 2018

Enhanced Mucosal Defense and Reduced Tumor Burden in Mice with the Compromised Negative Regulator IRAK-M.

EBioMedicine 2017 Feb 3;15:36-47. Epub 2016 Dec 3.

Department of Biomedical Sciences and Pathobiology, VA-MD College of Veterinary Medicine, Blacksburg, Virginia 24061, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.11.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233813PMC
February 2017

Sinorhizobium meliloti chemotaxis to quaternary ammonium compounds is mediated by the chemoreceptor McpX.

Mol Microbiol 2017 01 11;103(2):333-346. Epub 2016 Nov 11.

Department of Biological Sciences, Life Sciences I, Virginia Tech, Blacksburg, VA, 24061, USA.

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http://dx.doi.org/10.1111/mmi.13561DOI Listing
January 2017

Amylin Amyloid Inhibition by Flavonoid Baicalein: Key Roles of Its Vicinal Dihydroxyl Groups of the Catechol Moiety.

Biochemistry 2016 08 27;55(31):4255-8. Epub 2016 Jul 27.

Department of Biochemistry, ‡Center for Drug Discovery, and §Translational Obesity Research Center, Virginia Polytechnic Institute & State University , Blacksburg, Virginia 24061, United States.

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http://dx.doi.org/10.1021/acs.biochem.6b00578DOI Listing
August 2016

Evolutionary correlations in flavonoid production across flowers and leaves in the Iochrominae (Solanaceae).

Phytochemistry 2016 Oct 10;130:119-27. Epub 2016 Jun 10.

Department of Ecology and Evolutionary Biology, University of Colorado-Boulder, Campus Box 334, Boulder, CO, 80309, USA.

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http://dx.doi.org/10.1016/j.phytochem.2016.05.007DOI Listing
October 2016

Ancient crops provide first archaeological signature of the westward Austronesian expansion.

Proc Natl Acad Sci U S A 2016 06 31;113(24):6635-40. Epub 2016 May 31.

School of Archaeology, University of Oxford, Oxford OX1 2PG, United Kingdom; Department of Archaeology, Max Planck Institute for the Science of Human History, D-07743 Jena, Germany.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1522714113
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http://dx.doi.org/10.1073/pnas.1522714113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914162PMC
June 2016

Analysis of the Spore Membrane Proteome in Clostridium perfringens Implicates Cyanophycin in Spore Assembly.

J Bacteriol 2016 06 27;198(12):1773-1782. Epub 2016 May 27.

Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA

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http://dx.doi.org/10.1128/JB.00212-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886753PMC
June 2016

Contribution of Individual Chemoreceptors to Sinorhizobium meliloti Chemotaxis Towards Amino Acids of Host and Nonhost Seed Exudates.

Mol Plant Microbe Interact 2016 Mar 22;29(3):231-9. Epub 2016 Feb 22.

1 Virginia Tech Department of Biological Sciences and.

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http://dx.doi.org/10.1094/MPMI-12-15-0264-RDOI Listing
March 2016

Genome-wide transcriptome analyses of developing seeds from low and normal phytic acid soybean lines.

BMC Genomics 2015 Dec 18;16:1074. Epub 2015 Dec 18.

Department of Crop and Soil Environmental Sciences, Virginia Tech, 185 AgQuad Lane, 24061, Blacksburg, VA, USA.

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http://dx.doi.org/10.1186/s12864-015-2283-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683714PMC
December 2015

Metabolite Profiling of Soybean Seed Extracts from Near-Isogenic Low and Normal Phytate Lines Using Orthogonal Separation Strategies.

J Agric Food Chem 2015 Nov 3;63(44):9879-87. Epub 2015 Nov 3.

Departments of Biochemistry, ‡Crop and Soil Environmental Sciences, §Biological Sciences, and Plant Pathology, and ∥Physiology and Weed Science, Virginia Tech , Blacksburg, Virginia 24061, United States.

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http://dx.doi.org/10.1021/acs.jafc.5b04002DOI Listing
November 2015

Characterization of the hypothalamic transcriptome in response to food deprivation reveals global changes in long noncoding RNA, and cell cycle response genes.

Genes Nutr 2015 Nov 16;10(6):48. Epub 2015 Oct 16.

Department of Human Nutrition Foods and Exercise, Virginia Tech, 1981 Kraft Drive (0913), Blacksburg, VA, 24061, USA.

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http://dx.doi.org/10.1007/s12263-015-0496-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608919PMC
November 2015

A metabolomic assessment of NAC154 transcription factor overexpression in field grown poplar stem wood.

Phytochemistry 2015 Jul 11;115:112-20. Epub 2015 Mar 11.

Department of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2015.02.013DOI Listing
July 2015

Levels of germination proteins in Bacillus subtilis dormant, superdormant, and germinating spores.

PLoS One 2014 21;9(4):e95781. Epub 2014 Apr 21.

Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0095781PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994143PMC
June 2015

Sinorhizobium meliloti chemoreceptor McpU mediates chemotaxis toward host plant exudates through direct proline sensing.

Appl Environ Microbiol 2014 Jun 21;80(11):3404-15. Epub 2014 Mar 21.

Virginia Tech, Department of Biological Sciences, Blacksburg, Virginia, USA.

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http://dx.doi.org/10.1128/AEM.00115-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018860PMC
June 2014

The exo-proteome and exo-metabolome of Nostoc punctiforme (Cyanobacteria) in the presence and absence of nitrate.

Arch Microbiol 2014 May 19;196(5):357-67. Epub 2014 Mar 19.

Department of Biochemistry, Virginia Tech, 143 Life Sciences 1, Blacksburg, VA, 24061-0910, USA.

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http://dx.doi.org/10.1007/s00203-014-0974-2DOI Listing
May 2014

A missing link in the transformation from asymmetric to symmetric metallofullerene cages implies a top-down fullerene formation mechanism.

Nat Chem 2013 Oct 15;5(10):880-5. Epub 2013 Sep 15.

1] Virginia Tech Carilion Research Institute, Roanoke, Virginia 24016, USA [2] Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.

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http://dx.doi.org/10.1038/nchem.1748DOI Listing
October 2013

Effects of exogenous auxin and ethylene on the Arabidopsis root proteome.

Phytochemistry 2012 Dec 16;84:18-23. Epub 2012 Sep 16.

Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24061-0406, USA.

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http://dx.doi.org/10.1016/j.phytochem.2012.08.007DOI Listing
December 2012

Analysis of T-DNA alleles of flavonoid biosynthesis genes in Arabidopsis ecotype Columbia.

BMC Res Notes 2012 Sep 4;5:485. Epub 2012 Sep 4.

Department of Biological Sciences, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1186/1756-0500-5-485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526476PMC
September 2012

Connecting the dots between PubMed abstracts.

PLoS One 2012 3;7(1):e29509. Epub 2012 Jan 3.

Department of Computer Science, Virginia Tech, Blacksburg, Virginia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029509PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250456PMC
May 2012

Characterization of flavonol glycosides in individual Arabidopsis root tips by flow injection electrospray mass spectrometry.

Phytochemistry 2012 Jan 8;73(1):114-8. Epub 2011 Nov 8.

Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24061-0406, USA.

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http://dx.doi.org/10.1016/j.phytochem.2011.09.013DOI Listing
January 2012

Auxin and ethylene induce flavonol accumulation through distinct transcriptional networks.

Plant Physiol 2011 May 22;156(1):144-64. Epub 2011 Mar 22.

Department of Biology, Wake Forest University, Winston-Salem, North Carolina 27109, USA.

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http://dx.doi.org/10.1104/pp.111.172502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091047PMC
May 2011

Mass spectral analyses of corn stover prehydrolysates to assess conditioning processes.

J Agric Food Chem 2010 Dec 16;58(24):12642-9. Epub 2010 Nov 16.

Department of Biochemistry, Virginia Tech, Blacksburg, Virginia 24061-0910, United States.

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http://dx.doi.org/10.1021/jf1031197DOI Listing
December 2010

Characterization of recombinant UDP-galactopyranose mutase from Aspergillus fumigatus.

Arch Biochem Biophys 2010 Oct 6;502(1):31-8. Epub 2010 Jul 6.

Department of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1016/j.abb.2010.06.035DOI Listing
October 2010

Reverse engineering dynamic temporal models of biological processes and their relationships.

Proc Natl Acad Sci U S A 2010 Jul 22;107(28):12511-6. Epub 2010 Jun 22.

Department of Computer Science, Virginia Tech, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1073/pnas.1006283107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906599PMC
July 2010

Recombinant expression, purification, and characterization of ThmD, the oxidoreductase component of tetrahydrofuran monooxygenase.

Arch Biochem Biophys 2010 Apr 14;496(2):123-31. Epub 2010 Feb 14.

Department of Biochemistry, Virginia Tech., Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1016/j.abb.2010.02.006DOI Listing
April 2010

Simultaneously segmenting multiple gene expression time courses by analyzing cluster dynamics.

J Bioinform Comput Biol 2009 Apr;7(2):339-56

Department of Computer Science, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1142/s0219720009004114DOI Listing
April 2009

Investigating the fate of activated sludge extracellular proteins in sludge digestion using sodium dodecyl sulfate polyacrylamide gel electrophoresis.

Water Environ Res 2008 Dec;80(12):2219-27

Department of Civil and Environmental Engineering, University of Massachusetts, Amherst, MA 01003, USA.

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http://dx.doi.org/10.2175/106143008x325791DOI Listing
December 2008

Structural and membrane binding properties of the prickle PET domain.

Biochemistry 2008 Dec;47(51):13524-36

Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.

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https://pubs.acs.org/doi/10.1021/bi801037h
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http://dx.doi.org/10.1021/bi801037hDOI Listing
December 2008

Evaluation of the extracellular proteins in full-scale activated sludges.

Water Res 2008 Aug 21;42(14):3879-89. Epub 2008 Jun 21.

Department of Civil and Environmental Engineering, University of Massachusetts, Amherst, MA 01003, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00431354080023
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http://dx.doi.org/10.1016/j.watres.2008.05.014DOI Listing
August 2008

Using relative importance methods to model high-throughput gene perturbation screens.

Comput Syst Bioinformatics Conf 2008 ;7:225-35

Department of Computer Science, Virginia Tech, Blacksburg, VA 24061, USA.

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August 2009

CMGSDB: integrating heterogeneous Caenorhabditis elegans data sources using compositional data mining.

Nucleic Acids Res 2008 Jan 16;36(Database issue):D69-76. Epub 2007 Oct 16.

Department of Computer Science and Department of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1093/nar/gkm804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238953PMC
January 2008

Activated stress response pathways within multicellular aggregates utilize an autocrine component.

Cell Signal 2007 Apr 28;19(4):772-81. Epub 2006 Nov 28.

Department of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1016/j.cellsig.2006.10.005DOI Listing
April 2007

Nicotinamide extends the replicative life span of primary human cells.

Mech Ageing Dev 2006 Jun 20;127(6):511-4. Epub 2006 Mar 20.

Department of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1016/j.mad.2006.02.001DOI Listing
June 2006

Transcriptional response of Saccharomyces cerevisiae to desiccation and rehydration.

Appl Environ Microbiol 2005 Dec;71(12):8752-63

Virginia Tech Center for Genomics, Department of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1128/AEM.71.12.8752-8763.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1317403PMC
December 2005

Desiccation tolerance of prokaryotes: application of principles to human cells.

Integr Comp Biol 2005 Nov;45(5):800-9

Virginia Tech Center for Genomics, Department of Biochemistry, Virginia Tech, Blacksburg, Virginia 24061.

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http://dx.doi.org/10.1093/icb/45.5.800DOI Listing
November 2005

UV irradiation and desiccation modulate the three-dimensional extracellular matrix of Nostoc commune (Cyanobacteria).

J Biol Chem 2005 Dec 27;280(48):40271-81. Epub 2005 Sep 27.

Virginia Tech Center for Genomics, Department of Biochemistry, Virginia Tech, Blacksburg, Virginia 24061, USA.

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http://dx.doi.org/10.1074/jbc.M505961200DOI Listing
December 2005

Long term metabolic arrest and recovery of HEK293 spheroids involves NF-kappaB signaling and sustained JNK activation.

J Cell Physiol 2006 Feb;206(2):526-36

Department of Biochemistry, Virginia Tech Center for Genomics, Virginia Tech, Blacksburg, Virginia, USA.

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http://dx.doi.org/10.1002/jcp.20499DOI Listing
February 2006

A phosphohexomutase from the archaeon Sulfolobus solfataricus is covalently modified by phosphorylation on serine.

J Bacteriol 2005 Jun;187(12):4270-5

Department of Biochemistry and Virginia Institute for Genomics, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.

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http://dx.doi.org/10.1128/JB.187.12.4270-4275.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1151728PMC
June 2005

A preliminary investigation of the Nostoc punctiforme proteome.

Biochem Biophys Res Commun 2004 May;317(4):1121-7

Department of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1016/j.bbrc.2004.03.173DOI Listing
May 2004

Unusual water flux in the extracellular polysaccharide of the cyanobacterium Nostoc commune.

Appl Environ Microbiol 2003 Sep;69(9):5679-84

Virginia Tech Center for Genomics, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC194923PMC
http://dx.doi.org/10.1128/aem.69.9.5679-5684.2003DOI Listing
September 2003

Phosphoprotein with phosphoglycerate mutase activity from the archaeon Sulfolobus solfataricus.

J Bacteriol 2003 Apr;185(7):2112-21

Department of Biochemistry and Virginia Institute for Genomics, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151489PMC
http://dx.doi.org/10.1128/jb.185.7.2112-2121.2003DOI Listing
April 2003