Richard Haynes

Richard Haynes

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Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration.

J Antimicrob Chemother 2019 Oct;74(10):2965-2973

Australian Defence Force Malaria and Infectious Disease Institute, Brisbane, Australia.

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http://dx.doi.org/10.1093/jac/dkz290DOI Listing
October 2019

Long term outcomes in monoclonal gammopathy of renal significance.

Br J Haematol 2019 Sep 29;186(5):706-716. Epub 2019 May 29.

Department of Haematology, Oxford University Hospitals NHS Foundation Trust, UK.

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http://dx.doi.org/10.1111/bjh.15987DOI Listing
September 2019

Serious Adverse Effects of Extended-release Niacin/Laropiprant: Results From the Heart Protection Study 2-Treatment of HDL to Reduce the Incidence of Vascular Events (HPS2-THRIVE) Trial.

Clin Ther 2019 Sep 22;41(9):1767-1777. Epub 2019 Aug 22.

MRC Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom; Clinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.clinthera.2019.06.012DOI Listing
September 2019

Pathophysiology and management of monoclonal gammopathy of renal significance.

Blood Adv 2019 Aug;3(15):2409-2423

Department of Haematology, Oxford University Hospitals, NHS Foundation Trust, Oxford, United Kingdom.

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http://dx.doi.org/10.1182/bloodadvances.2019031914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693003PMC
August 2019

efficacies, ADME, and pharmacokinetic properties of phenoxazine derivatives active against .

Antimicrob Agents Chemother 2019 Aug 19. Epub 2019 Aug 19.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, South Africa.

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http://dx.doi.org/10.1128/AAC.01010-19DOI Listing
August 2019

Cost-effectiveness of lipid lowering with statins and ezetimibe in chronic kidney disease.

Kidney Int 2019 Jul 12;96(1):170-179. Epub 2019 Mar 12.

Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, UK; Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2019.01.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595178PMC
July 2019

Outcomes after Epiretinal Membrane Surgery with or Without Internal Limiting Membrane Peeling.

Ophthalmol Ther 2019 Jun 19;8(2):297-303. Epub 2019 Apr 19.

Bristol Eye Hospital, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.

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http://link.springer.com/10.1007/s40123-019-0185-7
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http://dx.doi.org/10.1007/s40123-019-0185-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513918PMC
June 2019

The evaluation of the anti-cancer drug elesclomol that forms a redox-active copper chelate as a potential anti-tubercular drug.

IUBMB Life 2019 05 14;71(5):532-538. Epub 2019 Jan 14.

Centre of Excellence for Pharmaceutical Sciences, Faculty of Health Sciences, North-West University, Potchefstroom, South Africa.

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http://dx.doi.org/10.1002/iub.2002DOI Listing
May 2019

Chronic kidney disease, heart failure and neprilysin inhibition.

Nephrol Dial Transplant 2019 Apr 26. Epub 2019 Apr 26.

Medical Research Council Population Health Research Unit, University of Oxford, Headington, Oxford, UK.

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http://dx.doi.org/10.1093/ndt/gfz058DOI Listing
April 2019

Anti-Mycobacterial Peroxides: A new class of agents for development against tuberculosis.

Med Chem 2019 Apr 30. Epub 2019 Apr 30.

School of Biomedical Sciences, Charles Sturt University. Orange, NSW 2800. Australia.

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http://dx.doi.org/10.2174/1573406415666190430143535DOI Listing
April 2019

The Evaluation of Metal Co-ordinating Bis-Thiosemicarbazones as Potential Anti-malarial Agents.

Med Chem 2019 ;15(1):51-58

School of Biomedical Sciences, Charles Sturt University, Orange, NSW 2800, Australia.

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http://dx.doi.org/10.2174/1573406414666180525132204DOI Listing
February 2019

Growth of Rhodes grass and leaching of ions from seawater neutralized bauxite residues after amendment with gypsum and organic wastes.

J Environ Manage 2019 Feb 31;231:596-604. Epub 2018 Oct 31.

School of Medical Engineering, Foshan University, Foshan, Guangdong, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03014797183121
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http://dx.doi.org/10.1016/j.jenvman.2018.10.083DOI Listing
February 2019

An ADME and Pharmacokinetic Study of Novel TB-Active Decoquinate Derivatives.

Front Pharmacol 2019 18;10:120. Epub 2019 Feb 18.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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https://www.frontiersin.org/article/10.3389/fphar.2019.00120
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http://dx.doi.org/10.3389/fphar.2019.00120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387968PMC
February 2019

Topical Delivery of Artemisone, Clofazimine and Decoquinate Encapsulated in Vesicles and Their In vitro Efficacy Against Mycobacterium tuberculosis.

AAPS PharmSciTech 2019 Jan 2;20(1):33. Epub 2019 Jan 2.

Centre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom, 2520, South Africa.

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http://dx.doi.org/10.1208/s12249-018-1251-5DOI Listing
January 2019

Competitive adsorption and desorption of arsenate, vanadate, and molybdate onto the low-cost adsorbent materials alum water treatment sludge and bauxite.

Environ Sci Pollut Res Int 2018 Dec 3;25(34):34053-34062. Epub 2018 Oct 3.

School of Medical Engineering, Foshan University, Foshan, Guangdong, China.

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http://dx.doi.org/10.1007/s11356-018-3301-7DOI Listing
December 2018

Absorptive and Secretory Transport of Selected Artemisinin Derivatives Across Caco-2 Cell Monolayers.

Curr Drug Deliv 2018 ;15(8):1183-1192

Pharmacen™, Centre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa.

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http://dx.doi.org/10.2174/1567201815666180518125113DOI Listing
October 2018

Properties of seawater neutralized bauxite residues and changes in chemical, physical and microbial properties induced by additions of gypsum and organic matter.

J Environ Manage 2018 Oct 26;223:489-494. Epub 2018 Jun 26.

School of Medical Engineering, Foshan University, Foshan, Guangdong, China. Electronic address:

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http://dx.doi.org/10.1016/j.jenvman.2018.06.070DOI Listing
October 2018

Synthesis, antimalarial activities and cytotoxicities of amino-artemisinin-1,2-disubstituted ferrocene hybrids.

Bioorg Med Chem Lett 2018 10 28;28(19):3161-3163. Epub 2018 Aug 28.

Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.08.037DOI Listing
October 2018

Increased leaching and addition of amendments improve the properties of seawater-neutralized bauxite residue as a growth medium.

Environ Sci Pollut Res Int 2018 Sep 27;25(25):25476-25485. Epub 2018 Jun 27.

School of Medical Engineering, Foshan University, Foshan, Guangdong, China.

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http://dx.doi.org/10.1007/s11356-018-2564-3DOI Listing
September 2018

Formulation of Natural Oil Nano-Emulsions for the Topical Delivery of Clofazimine, Artemisone and Decoquinate.

Pharm Res 2018 Aug 7;35(10):186. Epub 2018 Aug 7.

Centre of Excellence for Pharmaceutical Sciences (Pharmacen™), North-West University, Private Bag X6001, Potchefstroom, 2520, South Africa.

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http://dx.doi.org/10.1007/s11095-018-2471-9DOI Listing
August 2018

Facile Preparation of -Glycosylated 10-Piperazinyl Artemisinin Derivatives and Evaluation of Their Antimalarial and Cytotoxic Activities.

Molecules 2018 Jul 13;23(7). Epub 2018 Jul 13.

Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.3390/molecules23071713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100044PMC
July 2018

PCSK9 inhibition: ready for prime time in CKD?

Kidney Int 2018 06;93(6):1267-1269

Clinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK; Medical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2018.01.030DOI Listing
June 2018

Cocrystals of the antimalarial drug 11-azaartemisinin with three alkenoic acids of 1:1 or 2:1 stoichiometry.

Acta Crystallogr C Struct Chem 2018 06 24;74(Pt 6):742-751. Epub 2018 May 24.

Department of Chemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1107/S2053229618006320DOI Listing
June 2018

Declining comorbidity-adjusted mortality rates in English patients receiving maintenance renal replacement therapy.

Kidney Int 2018 05 12;93(5):1165-1174. Epub 2018 Feb 12.

Medical Research Council Population Health Research Unit, Nuffield Department of Population Health (NDPH), University of Oxford, Oxford, UK; Oxford Kidney Unit, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912929PMC
May 2018

Lowering LDL cholesterol reduces cardiovascular risk independently of presence of inflammation.

Kidney Int 2018 04 14;93(4):1000-1007. Epub 2017 Nov 14.

Medical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978933PMC
April 2018

The role of lipoprotein (a) in chronic kidney disease.

J Lipid Res 2018 04 29;59(4):577-585. Epub 2018 Jan 29.

Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1194/jlr.R083626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880503PMC
April 2018

Escalation of competition into conflict in competitive networks of Formula One drivers.

Proc Natl Acad Sci U S A 2018 04 26;115(15):E3361-E3367. Epub 2018 Mar 26.

European School of Management and Technology, 10178 Berlin, Germany

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http://dx.doi.org/10.1073/pnas.1717303115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899443PMC
April 2018

ASCEND: A Study of Cardiovascular Events iN Diabetes: Characteristics of a randomized trial of aspirin and of omega-3 fatty acid supplementation in 15,480 people with diabetes.

Am Heart J 2018 04 24;198:135-144. Epub 2017 Dec 24.

Clinical Trial Service Unit, Richard Doll Building, Old Road Campus, Roosevelt Drive, Headington, Oxford; Medical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1016/j.ahj.2017.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971211PMC
April 2018

Effect of pH and added slag on the extractability of Si in two Si-deficient sugarcane soils.

Chemosphere 2018 Feb 7;193:431-437. Epub 2017 Nov 7.

School of Medical Engineering, Foshan University, Foshan, Guangdong, China. Electronic address:

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http://dx.doi.org/10.1016/j.chemosphere.2017.10.175DOI Listing
February 2018

Synthesis, in vitro antimalarial activities and cytotoxicities of amino-artemisinin-ferrocene derivatives.

Bioorg Med Chem Lett 2018 02 26;28(3):289-292. Epub 2017 Dec 26.

Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.12.057DOI Listing
February 2018

Impact of Apolipoprotein(a) Isoform Size on Lipoprotein(a) Lowering in the HPS2-THRIVE Study.

Circ Genom Precis Med 2018 02;11(2):e001696

From the Medical Research Council Population Health Research Unit (S.P., M.R.H., R.H., C.B., J.A.); and the Clinical Trial Service Unit and Epidemiological Studies Unit (S.P., J.C.H., M.R.H., E.V.-M., R.H., A.O., C.B., R.C., M.L., J.A.), Nuffield Department of Population Health, University of Oxford, United Kingdom; Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington, Seattle (S.M.); and Center for Preventive Medicine, University of Oslo, Norway (T.R.P.). A complete list of collaborators in HPS2-THRIVE (Heart Protection Study 2-Treatment of HDL to Reduce the Incidence of Vascular Events) is given in reference 13.

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http://dx.doi.org/10.1161/CIRCGEN.117.001696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841847PMC
February 2018

Preliminary Evaluation of Artemisinin-Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis.

ChemMedChem 2018 01 15;13(1):67-77. Epub 2017 Dec 15.

Centre of Excellence for Pharmaceutical Sciences, Faculty of Health Sciences, North-West University, Potchefstroom, 2520, South Africa.

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http://dx.doi.org/10.1002/cmdc.201700579DOI Listing
January 2018

Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Neospora caninum and Comparative Cytotoxicities.

ChemMedChem 2017 12 6;12(24):2094-2098. Epub 2017 Dec 6.

Centre of Excellence for Pharmaceutical Sciences, Faculty of Health Sciences, North-West University, Potchefstroom, 2520, South Africa.

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http://dx.doi.org/10.1002/cmdc.201700600DOI Listing
December 2017

Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Asexual and Transmissible Malaria Parasites.

ChemMedChem 2017 12 8;12(24):2086-2093. Epub 2017 Dec 8.

Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, 2520, South Africa.

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http://dx.doi.org/10.1002/cmdc.201700599DOI Listing
December 2017

Elimination of Schistosoma mansoni in infected mice by slow release of artemisone.

Int J Parasitol Drugs Drug Resist 2017 08 4;7(2):241-247. Epub 2017 May 4.

The Kuvin Center for the Study of Infectious and Tropical Diseases, The Department of Microbiology and Molecular Genetics, Hebrew University of Jerusalem-Hadassah Medical School, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.ijpddr.2017.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430492PMC
August 2017

Outcomes of Elderly Patients with Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitis Treated with Immunosuppressive Therapy.

Nephron 2016 20;133(4):223-31. Epub 2016 Jul 20.

Oxford Kidney Unit, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

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http://dx.doi.org/10.1159/000447018DOI Listing
February 2017

Evidence for Reverse Causality in the Association Between Blood Pressure and Cardiovascular Risk in Patients With Chronic Kidney Disease.

Hypertension 2017 02 27;69(2):314-322. Epub 2016 Dec 27.

From the Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), (W.H., N.S., P.K.J., M.M., J.E., R.H., S.L., C.A.R., M.J.L., C.B.) and Medical Research Council-Population Health Research Unit (MRC-PHRU) (P.K.J., J.E., R.H., S.L., C.B.), Nuffield Department of Population Health (NDPH), University of Oxford, United Kingdom; Centre for Nephrology, University College London, United Kingdom (D.C.W.); Dunedin School of Medicine, University of Otago, New Zealand (R.W.); Newcastle-upon-Tyne Hospitals NHS Foundation Trust, United Kingdom (C.T.); National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD (L.A.); and Department of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland (A.W.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222554PMC
February 2017

Sequential Hypothesis Testing to Characterise the Learning Curve and Monitor Surgical Performance in Retinal Detachment Surgery.

Ophthalmologica 2016 11;235(3):157-62. Epub 2016 Feb 11.

Bristol Eye Hospital, Bistrol, UK.

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http://dx.doi.org/10.1159/000443749DOI Listing
December 2016

Rhegmatogenous retinal detachment following intravitreal ocriplasmin.

Graefes Arch Clin Exp Ophthalmol 2016 Dec 8;254(12):2333-2338. Epub 2016 Jun 8.

Sunderland Eye Infirmary, Queen Alexandra Road, Sunderland, SR2 9HP, UK.

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http://dx.doi.org/10.1007/s00417-016-3398-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116307PMC
December 2016

Direct cost of pars plana vitrectomy for the treatment of macular hole, epiretinal membrane and vitreomacular traction: a bottom-up approach.

Eur J Health Econ 2016 Nov 24;17(8):991-999. Epub 2015 Nov 24.

LSE Health and Social Care, London School of Economics and Political Science, Houghton Street, London, WC2A 2AE, UK.

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http://dx.doi.org/10.1007/s10198-015-0741-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047926PMC
November 2016

Risk factors for retinal detachment following cataract surgery: the impact of posterior capsular rupture.

Br J Ophthalmol 2016 11 8;100(11):1461-1465. Epub 2016 Feb 8.

Department of Ophthalmology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK.

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http://dx.doi.org/10.1136/bjophthalmol-2015-307729DOI Listing
November 2016

The Safety and Efficacy of Mineralocorticoid Receptor Antagonists in Patients Who Require Dialysis: A Systematic Review and Meta-analysis.

Am J Kidney Dis 2016 Oct 3;68(4):591-598. Epub 2016 Jun 3.

Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada; Department of Medicine, McMaster University, Ontario, Canada; Population Health Research Institute, Hamilton Health Sciences/McMaster University, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2016.04.011DOI Listing
October 2016

Effect of Processing Delay and Storage Conditions on Urine Albumin-to-Creatinine Ratio.

Clin J Am Soc Nephrol 2016 10 21;11(10):1794-1801. Epub 2016 Sep 21.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, Oxford, United Kingdom.

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http://dx.doi.org/10.2215/CJN.13341215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053802PMC
October 2016

Retinoschisis transposition following a retinal detachment repair.

GMS Ophthalmol Cases 2015 15;5:Doc07. Epub 2015 Sep 15.

Retina Unit, Bristol Eye Hospital, Bristol University Hospitals NHS Trust, Bristol, United Kingdom.

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http://dx.doi.org/10.3205/oc000029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015630PMC
September 2016

Smoking and Adverse Outcomes in Patients With CKD: The Study of Heart and Renal Protection (SHARP).

Am J Kidney Dis 2016 Sep 23;68(3):371-80. Epub 2016 Apr 23.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2016.02.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996629PMC
September 2016

The Case for Development of 11-Aza-artemisinins for Malaria.

Curr Med Chem 2015 ;22(31):3607-30

Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa.

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http://dx.doi.org/10.2174/0929867322666150729115752DOI Listing
August 2016

Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activities.

Bioorg Med Chem Lett 2016 07 9;26(13):3006-3009. Epub 2016 May 9.

Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.05.024DOI Listing
July 2016

In vitro activity of artemisone and artemisinin derivatives against extracellular and intracellular Helicobacter pylori.

Int J Antimicrob Agents 2016 Jul 6;48(1):101-105. Epub 2016 May 6.

Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1016/j.ijantimicag.2016.03.018DOI Listing
July 2016

Methylene Homologues of Artemisone: An Unexpected Structure-Activity Relationship and a Possible Implication for the Design of C10-Substituted Artemisinins.

ChemMedChem 2016 07 7;11(13):1469-79. Epub 2016 Jun 7.

Centre of Excellence for Pharmaceutical Sciences, Faculty of Health Sciences, North-West University, Potchefstroom, 2520, South Africa.

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http://doi.wiley.com/10.1002/cmdc.201600011
Publisher Site
http://dx.doi.org/10.1002/cmdc.201600011DOI Listing
July 2016

Effects of Vascular and Nonvascular Adverse Events and of Extended-Release Niacin With Laropiprant on Health and Healthcare Costs.

Circ Cardiovasc Qual Outcomes 2016 07 12;9(4):348-54. Epub 2016 Jul 12.

From the Health Economics Research Centre (S.K., A.G., B.M.) and Clinical Trial Service Unit and Epidemiological Studies Unit (R.H., J.C.H., S.P., M.J.L., R.C., J.A.), Nuffield Department of Population Health, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/CIRCOUTCOMES.115.002592DOI Listing
July 2016

Cost-effective recruitment methods for a large randomised trial in people with diabetes: A Study of Cardiovascular Events iN Diabetes (ASCEND).

Trials 2016 06 13;17(1):286. Epub 2016 Jun 13.

Nuffield Department of Population Health (NDPH), Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Richard Doll Building, Old Road Campus, Oxford, OX3 7LF, UK.

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http://dx.doi.org/10.1186/s13063-016-1354-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907276PMC
June 2016

In vitro skin permeation of artemisone and its nano-vesicular formulations.

Int J Pharm 2016 Apr 27;503(1-2):1-7. Epub 2016 Feb 27.

Centre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2016.02.041DOI Listing
April 2016

Niacin: old habits die hard.

Heart 2016 Feb;102(3):170-1

The George Institute for Global Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/heartjnl-2015-308558DOI Listing
February 2016

Repurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse model.

Vet Res 2016 Feb 17;47:32. Epub 2016 Feb 17.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, 3012, Bern, Switzerland.

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http://dx.doi.org/10.1186/s13567-016-0317-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756515PMC
February 2016

Impact of Educational Attainment on Health Outcomes in Moderate to Severe CKD.

Am J Kidney Dis 2016 Jan 16;67(1):31-9. Epub 2015 Sep 16.

Health Economics Research Centre, University of Oxford, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2015.07.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685934PMC
January 2016

In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells.

Nanomedicine 2015 Nov 15;11(8):2041-50. Epub 2015 Aug 15.

Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2015.07.010DOI Listing
November 2015

Evidence for the prevention and treatment of stroke in dialysis patients.

Semin Dial 2015 Jan-Feb;28(1):35-47. Epub 2014 Jul 7.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom; Oxford Kidney Unit, Churchill Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.

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http://dx.doi.org/10.1111/sdi.12281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320775PMC
October 2015

Zonular Dehiscence at the Time of Combined Vitrectomy and Cataract Surgery After Intravitreal Ocriplasmin Injection.

JAMA Ophthalmol 2015 Sep;133(9):1091-2

Vitreo-Retinal Surgery Service, Bristol Eye Hospital, Bristol, United Kingdom.

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http://dx.doi.org/10.1001/jamaophthalmol.2015.1680DOI Listing
September 2015

In vitro effects of new artemisinin derivatives in Neospora caninum-infected human fibroblasts.

Int J Antimicrob Agents 2015 Jul 14;46(1):88-93. Epub 2015 Apr 14.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2015.02.020DOI Listing
July 2015

Thermoelastic and structural properties of ionically conducting cerate perovskites: (II) SrCeO3 between 1273 K and 1723 K.

Dalton Trans 2015 Jun 25;44(23):10773-84. Epub 2015 Feb 25.

ISIS Facility, STFC Rutherford Appleton Laboratory, Harwell Oxford, Didcot, Oxfordshire, OX11 0QX, UK.

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http://dx.doi.org/10.1039/c5dt00041fDOI Listing
June 2015

Neprilysin inhibition in chronic kidney disease.

Nephrol Dial Transplant 2015 May 18;30(5):738-43. Epub 2014 Aug 18.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.

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http://dx.doi.org/10.1093/ndt/gfu269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425478PMC
May 2015

Chronic kidney disease: Statins in chronic kidney disease: time to move on?

Nat Rev Nephrol 2015 May 24;11(5):262-3. Epub 2015 Mar 24.

Renal Division, University Hospital of Würzburg, Oberdürrbacherstrasse 6, 97080 Würzburg, Germany.

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http://dx.doi.org/10.1038/nrneph.2015.36DOI Listing
May 2015

Alemtuzumab induction therapy in kidney transplantation - Authors' reply.

Lancet 2015 Feb;385(9970):771

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/S0140-6736(15)60432-9DOI Listing
February 2015

Use of gel-based separator tubes to stabilise phosphate in mailed blood samples.

Clin Chim Acta 2015 Jan 2;439:112-4. Epub 2014 Oct 2.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), University of Oxford, UK.

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http://dx.doi.org/10.1016/j.cca.2014.09.025DOI Listing
January 2015

Inhibition of metalloproteinase-9 secretion and gene expression by artemisinin derivatives.

Acta Trop 2014 Dec 19;140:77-83. Epub 2014 Aug 19.

Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy.

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http://dx.doi.org/10.1016/j.actatropica.2014.08.008DOI Listing
December 2014

Assessment of the induction of dormant ring stages in Plasmodium falciparum parasites by artemisone and artemisone entrapped in Pheroid vesicles in vitro.

Antimicrob Agents Chemother 2014 Dec 6;58(12):7579-82. Epub 2014 Oct 6.

DST/NWU Preclinical Drug Development Platform, Faculty of Health Sciences, North-West University, Potchefstroom, South Africa

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http://dx.doi.org/10.1128/AAC.02707-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249507PMC
December 2014

A quantitative reverse-transcriptase PCR assay for the assessment of drug activities against intracellular Theileria annulata schizonts.

Int J Parasitol Drugs Drug Resist 2014 Dec 19;4(3):201-9. Epub 2014 Sep 19.

Institute for Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, 3012 Bern, Switzerland.

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http://dx.doi.org/10.1016/j.ijpddr.2014.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266814PMC
December 2014

Bow-string technique for iris pupilloplasty and posterior iris-claw artisan intraocular lens implant in traumatic aphakia with associated iris defects.

Retina 2014 Nov;34(11):2306-10

*Vitreo-Retinal Service Unit, Bristol Eye Hospital, University Hospitals Bristol NHS Trust, Bristol, United Kingdom; and †Medical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom.

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https://insights.ovid.com/crossref?an=00006982-201411000-000
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http://dx.doi.org/10.1097/IAE.0000000000000357DOI Listing
November 2014

Niacin for reduction of cardiovascular risk.

N Engl J Med 2014 11;371(20):1943-4

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http://dx.doi.org/10.1056/NEJMc1411240DOI Listing
November 2014

Effects of lowering LDL cholesterol on progression of kidney disease.

J Am Soc Nephrol 2014 Aug 1;25(8):1825-33. Epub 2014 May 1.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom;

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http://dx.doi.org/10.1681/ASN.2013090965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116066PMC
August 2014

Treatment of murine cerebral malaria by artemisone in combination with conventional antimalarial drugs: antiplasmodial effects and immune responses.

Antimicrob Agents Chemother 2014 Aug 9;58(8):4745-54. Epub 2014 Jun 9.

Department of Pathology and Bosch Institute, The University of Sydney, Sydney, Australia Department of Microbiology and Molecular Genetics, The Kuvin Center for the Study of Infectious and Tropical Diseases, The Hebrew University of Jerusalem, Jerusalem, Israel

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http://aac.asm.org/lookup/doi/10.1128/AAC.01553-13
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http://dx.doi.org/10.1128/AAC.01553-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135990PMC
August 2014

Recent progress in the development of anti-malarial quinolones.

Malar J 2014 Aug 30;13:339. Epub 2014 Aug 30.

Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa.

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http://dx.doi.org/10.1186/1475-2875-13-339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162983PMC
August 2014

Evaluating the contribution of the cause of kidney disease to prognosis in CKD: results from the Study of Heart and Renal Protection (SHARP).

Am J Kidney Dis 2014 Jul 5;64(1):40-8. Epub 2014 Mar 5.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2013.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068325PMC
July 2014

The effect of the Pheroid delivery system on the in vitro metabolism and in vivo pharmacokinetics of artemisone.

Expert Opin Drug Metab Toxicol 2014 Mar 10;10(3):313-25. Epub 2014 Feb 10.

North-West University, Faculty of Health Sciences, DST/NWU Preclinical Drug Development Platform , Potchefstroom , South Africa +27 18 299 2281, +27 18 299 4467 ; +27 18 285 2233 ; ;

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http://dx.doi.org/10.1517/17425255.2014.885503DOI Listing
March 2014

Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.

Infect Disord Drug Targets 2013 Aug;13(4):217-77

Centre of Excellence for Pharmaceutical Sciences, School of Health Sciences, Private Bag X6001, North-West University, Potchefstroom Campus, 2520, South Africa.

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August 2013