Richard H Griffey

Richard H Griffey

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Richard H Griffey

Richard H Griffey

Publications by authors named "Richard H Griffey"

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Inhibitor-induced structural change in the HCV IRES domain IIa RNA.

Proc Natl Acad Sci U S A 2010 Apr 1;107(16):7263-8. Epub 2010 Apr 1.

Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1073/pnas.0911896107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867761PMC
April 2010

Trisaccharide mimetics of the aminoglycoside antibiotic neomycin.

Org Biomol Chem 2006 Apr 22;4(7):1328-37. Epub 2006 Feb 22.

Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.

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http://dx.doi.org/10.1039/b517725aDOI Listing
April 2006

An efficient synthesis of gougerotin and related analogues using solid- and solution-phase methodology.

Org Lett 2005 Aug;7(16):3429-32

Ibis Therapeutics, a Division of Isis Pharmaceuticals, Inc., 1896 Rutherford Avenue, Carlsbad, CA 52008, USA.

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http://dx.doi.org/10.1021/ol0507322DOI Listing
August 2005

Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.

J Med Chem 2005 Feb;48(4):901-4

Department of Medicinal Chemistry, Isis Pharmaceuticals, 2292 Faraday Avenue, Carlsbad, California 92008, USA.

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http://dx.doi.org/10.1021/jm049167jDOI Listing
February 2005

Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site.

Angew Chem Int Ed Engl 2004 Dec;43(48):6735-8

Institut de biologie moléculaire et cellulaire UPR9002 CNRS, Université Louis Pasteur, 15 rue René Descartes, 67084 Strasbourg Cedex, France.

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http://dx.doi.org/10.1002/anie.200462092DOI Listing
December 2004

Disaccharide mimetics of the aminoglycoside antibiotic neamine.

Chembiochem 2004 Sep;5(9):1228-36

Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.

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http://doi.wiley.com/10.1002/cbic.200400105
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http://dx.doi.org/10.1002/cbic.200400105DOI Listing
September 2004

A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome.

Biosystems 2002 Mar-May;65(2-3):157-77

Ibis Therapeutics, Isis Pharmaceuticals, Inc, 2292 Faraday Ave, Carlsbad, CA 92008, USA.

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http://dx.doi.org/10.1016/s0303-2647(02)00013-8DOI Listing
November 2003

Discovery of RNA structural elements using evolutionary computation.

Nucleic Acids Res 2002 Dec;30(23):5310-7

Natural Selection Inc., 3333 North Torrey Pines Court, Suite 200, La Jolla, CA 92037, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137967PMC
http://dx.doi.org/10.1093/nar/gkf653DOI Listing
December 2002

Converting solution macromolecular thermodynamic properties into gas-phase mass spectrometry observations.

Chem Biol 2002 Sep;9(9):958-9

Isis Pharmaceuticals, Carlsbad, CA 92008, USA.

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http://dx.doi.org/10.1016/s1074-5521(02)00221-1DOI Listing
September 2002

SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets.

J Med Chem 2002 Aug;45(18):3816-9

Ibis Therapeutics, A Division of Isis Pharmaceuticals, Inc., 2292 Faraday Avenue, Carlsbad, California 92008, USA.

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http://dx.doi.org/10.1021/jm0255466DOI Listing
August 2002