Richard H Aster

Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA; Medical Sciences Institute, BloodCenter of Wisconsin, Milwaukee, WI, USA; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, USA. Electronic address:

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May 2018

Patients treated with oxaliplatin are at risk for thrombocytopenia caused by multiple drug-dependent antibodies.

Authors:

Brian R Curtis Yen-Michael S Hsu Nikolai Podoltsev Jill Lacy Susanna Curtis Michael S Samuel Kristin Zutavern Robert A DeSimone Daniel W Bougie Richard H Aster

Blood 2018 03 12;131(13):1486-1489. Epub 2018 Feb 12.

Blood Research Institute, BloodCenter of Wisconsin, and.

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March 2018

Normal plasma IgG inhibits HIT antibody-mediated platelet activation: implications for therapeutic plasma exchange.

Authors:

Curtis G Jones Shannon M Pechauer Brian R Curtis Daniel W Bougie Richard H Aster Anand Padmanabhan

Blood 2018 02 19;131(6):703-706. Epub 2017 Dec 19.

Medical Sciences Institute.

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February 2018

A Platelet Factor 4-Dependent Platelet Activation Assay Facilitates Early Detection of Pathogenic Heparin-Induced Thrombocytopenia Antibodies.

Authors:

Curtis G Jones Shannon M Pechauer Brian R Curtis Daniel W Bougie Mehraboon S Irani Binod Dhakal Brenda Pierce Richard H Aster Anand Padmanabhan

Chest 2017 10;152(4):e77-e80

Medical Sciences Institute, BloodCenter of Wisconsin, Milwaukee, WI; Department of Pathology, Medical College of Wisconsin, Milwaukee, WI. Electronic address:

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October 2017

IVIg for Treatment of Severe Refractory Heparin-Induced Thrombocytopenia.

Authors:

Anand Padmanabhan Curtis G Jones Shannon M Pechauer Brian R Curtis Daniel W Bougie Mehraboon S Irani Barbara J Bryant Jack B Alperin Thomas G Deloughery Kevin P Mulvey Binod Dhakal Renren Wen Demin Wang Richard H Aster

Chest 2017 09 17;152(3):478-485. Epub 2017 Apr 17.

Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI; Department of Medicine, Medical College of Wisconsin, Milwaukee, WI.

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September 2017

TGF-β1 along with other platelet contents augments Treg cells to suppress anti-FVIII immune responses in hemophilia A mice.

Authors:

Dipica Haribhai Xiaofeng Luo Juan Chen Shuang Jia Linzheng Shi Jocelyn A Schroeder Hartmut Weiler Richard H Aster Martin J Hessner Jianda Hu Calvin B Williams Qizhen Shi

Blood Adv 2016 Dec;1(2):139-151

Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI; Children's Research Institute, Children's Hospital of Wisconsin, Milwaukee, WI; Midwest Athletes Against Childhood Cancer Fund Research Center, Milwaukee, WI; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI.

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December 2016

Immune destruction of human platelets in the NOD/scid mouse.

Authors:

Daniel W Bougie Dhirendra Nayak Richard H Aster

Transfusion 2016 10;56(10):2648-2649

Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI.

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October 2016

An unexpected development after surgery-post-transfusion purpura!

Authors:

Gavin Falk Charles G Winans Krista Bowens Daniel W Bougie Brian R Curtis Richard H Aster

Am J Hematol 2016 Aug 3;91(8):848-51. Epub 2016 Jun 3.

Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin.

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August 2016

A Novel PF4-Dependent Platelet Activation Assay Identifies Patients Likely to Have Heparin-Induced Thrombocytopenia/Thrombosis.

Authors:

Anand Padmanabhan Curtis G Jones Brian R Curtis Daniel W Bougie Mia J Sullivan Namrata Peswani Janice G McFarland Daniel Eastwood Demin Wang Richard H Aster

Chest 2016 09 19;150(3):506-15. Epub 2016 Feb 19.

Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI; Department of Medicine, Medical College of Wisconsin, Milwaukee, WI.

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September 2016

A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation.

Authors:

Rudy E Fuentes Sergei Zaitsev Hyun Sook Ahn Vincent Hayes M Anna Kowalska Michele P Lambert Yuhuan Wang Donald L Siegel Daniel W Bougie Richard H Aster Daniel D Myers Victoria Stepanova Douglas B Cines Vladimir R Muzykantov Mortimer Poncz

J Clin Invest 2016 Feb;126(2):483-94

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February 2016

Mechanism of quinine-dependent monoclonal antibody binding to platelet glycoprotein IIb/IIIa.

Authors:

Daniel W Bougie Julie Peterson Mark Rasmussen Richard H Aster

Blood 2015 Oct 9;126(18):2146-52. Epub 2015 Sep 9.

Blood Research Institute, BloodCenter of Wisconsin, and Department of Medicine, Medical College of Wisconsin, Milwaukee, WI.

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October 2015

Structural basis for quinine-dependent antibody binding to platelet integrin αIIbβ3.

Authors:

Jianghai Zhu Jieqing Zhu Daniel W Bougie Richard H Aster Timothy A Springer

Blood 2015 Oct 17;126(18):2138-45. Epub 2015 Aug 17.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA; Program in Cellular and Molecular Medicine, Children's Hospital Boston, Boston, MA;

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October 2015

A modified PF4-dependent, CD62p expression assay selectively detects serotonin-releasing antibodies in patients suspected of HIT.

Authors:

Anand Padmanabhan Curtis G Jones Daniel W Bougie Brian R Curtis Janice G McFarland Demin Wang Richard H Aster

Thromb Haemost 2015 Nov 16;114(6):1322-3. Epub 2015 Jul 16.

Anand Padmanabhan, MD PhD, Blood Center of Wisconsin, 8733 Watertown Plank Road, Milwaukee, WI 53226-3548, USA, Tel.: +1 414 937 6045, Fax: +1 414 933 6803, E-mail:

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November 2015

Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization.

Authors:

Ioanna A Comstock Michelle Longmire Richard H Aster Amin A Milki

Case Rep Obstet Gynecol 2015 25;2015:890610. Epub 2015 Feb 25.

Stanford University Medical Center, 900 Welch Road, Suite 350 MC 5800, Palo Alto, CA 94304, USA.

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March 2015

Drug-induced thrombotic microangiopathy: Experience of the Oklahoma Registry and the BloodCenter of Wisconsin.

Authors:

Jessica A Reese Daniel W Bougie Brian R Curtis Deirdra R Terrell Sara K Vesely Richard H Aster James N George

Am J Hematol 2015 May 25;90(5):406-10. Epub 2015 Feb 25.

Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.

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May 2015

Critical role of CD4 T cells in PF4/heparin antibody production in mice.

Authors:

Yongwei Zheng Mei Yu Anand Padmanabhan Richard H Aster Liudi Yuan Renren Wen Demin Wang

Blood 2015 Mar 16;125(11):1826-9. Epub 2015 Jan 16.

Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI.

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March 2015

A new low-frequency alloantigen (Kha(b) ) located on platelet glycoprotein IIIa as a cause of maternal sensitization leading to neonatal alloimmune thrombocytopenia.

Authors:

Mia J Sullivan Julie Peterson Janice G McFarland Daniel Bougie Richard H Aster Brian R Curtis

Transfusion 2015 Jun 15;55(6 Pt 2):1584-5. Epub 2014 Dec 15.

Platelet & Neutrophil Immunology Lab, BloodCenter of Wisconsin, Milwaukee, Wisconsin.

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June 2015

Heparin-independent, PF4-dependent binding of HIT antibodies to platelets: implications for HIT pathogenesis.

Authors:

Anand Padmanabhan Curtis G Jones Daniel W Bougie Brian R Curtis Janice G McFarland Demin Wang Richard H Aster

Blood 2015 Jan 23;125(1):155-61. Epub 2014 Oct 23.

Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI; Department of Medicine and.

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January 2015

Autoimmune hemolytic anemia and thrombocytopenia attributed to an intrauterine contraceptive device.

Authors:

Mohamad O Khawandanah Susan M Weiss Mohamad A Cherry Hossein Maymani George B Selby Richard H Aster James N George Jennifer L Holter Chakrabarty

Transfusion 2015 Mar 11;55(3):657-60. Epub 2014 Sep 11.

Hematology-Oncology Section, Department of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.

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March 2015

Transfusion-related acute lung injury-associated HNA-3a antibodies recognize complex determinants on choline transporter-like protein 2.

Authors:

Daniel W Bougie Julie A Peterson Adam J Kanack Brian R Curtis Richard H Aster

Transfusion 2014 Dec 21;54(12):3208-15. Epub 2014 May 21.

Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.

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December 2014

A case of oxaliplatin-induced immune-mediated thrombocytopenia.

Authors:

Seong Eun Suh Moon Ju Jang So Young Chong Richard H Aster Brian R Curtis Doyeun Oh

Blood Res 2014 Mar 24;49(1):61-4. Epub 2014 Mar 24.

Department of Internal Medicine, School of Medicine, CHA University, Seongnam, Korea.

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March 2014

Irinotecan-induced immune thrombocytopenia.

Authors:

Barry C Mirtsching James N George Richard H Aster Brian R Curtis

Am J Med Sci 2014 Feb;347(2):167-9

Medical City Dallas Hospital (BCM), Dallas, Texas Department of Medicine (JNG), College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma Platelet and Neutrophil Immunology Laboratory and Blood Research Institute (RHA, BRC), Blood Center of Wisconsin and Medical College of Wisconsin, Milwaukee, Wisconsin.

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February 2014

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