Richard G Langley

Richard G Langley

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Richard G Langley

Publications by authors named "Richard G Langley"

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Pharmacokinetics, Immunogenicity, and Efficacy of Etanercept in Pediatric Patients With Moderate to Severe Plaque Psoriasis.

J Clin Pharmacol 2018 03 6;58(3):340-346. Epub 2017 Nov 6.

Northwestern University Feinberg School of Medicine and the Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1002/jcph.1029DOI Listing
March 2018

Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis.

N Engl J Med 2016 Jul 8;375(4):345-56. Epub 2016 Jun 8.

From the Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago (K.B.G.); Oregon Medical Research Center, Portland (A.B.); K. Papp Clinical Research and Probity Medical Research, Waterloo, ON (K.A.P.), and the Department of Medicine, Division of Dermatology, Dalhousie University, Halifax, NS (R.G.L.) - both in Canada; the Department of Dermatology, University of Münster, Münster (T.L.), and SCIderm Research Institute and Dermatologikum Hamburg, Hamburg (K.R.) - both in Germany; the Department of Dermatology, Jichi Medical University, Shimotsuke-shi, Japan (M.O.); Lilly Research Laboratories, Eli Lilly, Indianapolis (D.A., S.G.B., D.K.B., G.S.C., J.E., R.J.K., T.M.M., B.J.N., O.O.O., R.J.S., F.Z., L.M.); and the Department of Dermatology, Saint Louis University School of Medicine, St. Louis (C.L.L.).

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http://dx.doi.org/10.1056/NEJMoa1512711DOI Listing
July 2016

Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis.

N Engl J Med 2015 Oct;373(14):1318-28

From the Icahn School of Medicine at Mount Sinai, New York (M.L., L.K.); University of Connecticut School of Medicine, Farmington (B.S.); Probity Medical Research (B.S., L.S., D.T.) and XLR8 Medical Research (D.T.), Windsor, ON, K Papp Medical Research (K.P.), Waterloo, ON, and Dalhousie University, Halifax, NS (R.G.L.) - all in Canada; Baylor University Medical Center, Dallas (A.M.); Northwestern University, Feinberg School of Medicine, Chicago (K.G.); Niepubliczny Zakład Opieki Zdrowotnej multiMedica, Wrocław (J.W.), and Lubelskie Centrum Diagnostyczne, Świdnik (T.B.) - both in Poland; Hospital de la Santa Creu i Sant Pau, Barcelona (L.P.); Veracity Clinical Research, Woolloongabba, QLD, Australia (L.S.); Florida Academic Dermatology Center, Miami (F.K.); University of Colorado, Denver (A.W.A.); Medizinische Universität Wien, Vienna, Austria (G.S.); Massachusetts General Hospital and Harvard Medical School, Boston (A.B.K.); Sorbonne Paris Cité Université Paris Diderot, Assistance Publique-Hôpitaux de Paris Hôpital Saint Louis, Paris (H.B.), Paul Sabatier University, Toulouse (C.P.), and University Hospital of Nice, Nice (J.-P.L.) - all in France; Kaiser Permanente Los Angeles Medical Center, Los Angeles (J.J.W.), Bakersfield Dermatology and Skin Cancer Medical Group, Bakersfield (J.C.), University of California, San Francisco, San Francisco (J.K.), and Amgen, Thousand Oaks (G.A., J.L., W.S., C.E.M., Y.S., N.E., P.K., B.K., A.N.) - all in California.; University of Texas Health Science Center, Houston (S.T.); DermResearch, Louisville, KY (L.K.); University of Rome Tor Vergata, Rome (S.C.); University of Utah Medical Center, Salt Lake City (K.C.D.); and the Psoriasis Treatment Center of Central New Jersey, East Windsor (J.B.).

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http://dx.doi.org/10.1056/NEJMoa1503824DOI Listing
October 2015

The 5-point Investigator's Global Assessment (IGA) Scale: A modified tool for evaluating plaque psoriasis severity in clinical trials.

J Dermatolog Treat 2015 Feb 20;26(1):23-31. Epub 2013 Dec 20.

Division of Dermatology, Department of Medicine, Queen Elizabeth II Health Sciences Centre, Dalhousie University , Halifax, Nova Scotia , Canada .

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http://dx.doi.org/10.3109/09546634.2013.865009DOI Listing
February 2015

Secukinumab in plaque psoriasis--results of two phase 3 trials.

N Engl J Med 2014 Jul 9;371(4):326-38. Epub 2014 Jul 9.

From Dalhousie University, Halifax, NS (R.G.L.), Clinical Research (K.P.) and Probity Medical Research (K.P., L.S.), Waterloo, ON, and Stratica Medical and Probity Medical Research, Edmonton, AB (N.W.) - all in Canada; University of Alabama, Birmingham (B.E.E.); Mount Sinai Hospital, New York (M.L.); Dermatologikum Hamburg and Georg-August-Universität, Göttingen, Germany (K.R.); Dermatology Centre, Salford Royal Hospital, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom (C.E.M.G.); Hospital de Sant Pau, Barcelona (L.P.); Jikei University School of Medicine, Tokyo (H.N.); Veracity Clinical Research, Woolloongabba, QLD, Australia (L.S.); Faculty of Medicine, Department of Dermatology, University of Iceland, Reykjavik (B.S.); Dermos, Guatemala City, Guatemala (E.R.); Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei (T.-F.T.); University of Texas Health Science Center and Center for Clinical Studies, Houston (S.T.); and Novartis Pharma, Basel, Switzerland (T.S., I.H., M.N., A.K., S.H., C.P.).

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http://dx.doi.org/10.1056/NEJMoa1314258DOI Listing
July 2014

Teaching empathy to undergraduate medical students using a temporary tattoo simulating psoriasis.

J Am Acad Dermatol 2012 Jul 7;67(1):93-9. Epub 2011 Oct 7.

Division of Dermatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1016/j.jaad.2011.07.023DOI Listing
July 2012

Dermacase. Can you identify this condition? Secondary syphilis.

Can Fam Physician 2012 Apr;58(4):409-11

Division of Dermatology, Dalhousie University, Halifax, NS.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325453PMC
April 2012

A phase III, randomized, controlled trial of the fully human IL-12/23 mAb briakinumab in moderate-to-severe psoriasis.

J Invest Dermatol 2012 Feb 20;132(2):304-14. Epub 2011 Oct 20.

Division of Dermatology, NorthShore University HealthSystem and University of Chicago, Pritzker School of Medicine, Chicago, Illinois 60077, USA.

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http://dx.doi.org/10.1038/jid.2011.304DOI Listing
February 2012

Cutaneous larva migrans.

Lancet 2011 Jun 19;377(9781):1948. Epub 2011 May 19.

Division of Dermatology, Dalhousie University, Halifax, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S014067361061149
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http://dx.doi.org/10.1016/S0140-6736(10)61149-XDOI Listing
June 2011

Academic branding: erythema ab igne and use of laptop computers.

CMAJ 2010 Dec 7;182(18):E857. Epub 2010 Sep 7.

Dalhousie University, Halifax, NS.

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http://dx.doi.org/10.1503/cmaj.091868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001533PMC
December 2010

Long-term etanercept in pediatric patients with plaque psoriasis.

J Am Acad Dermatol 2010 Nov 3;63(5):762-8. Epub 2010 Jun 3.

Children's Memorial Hospital and Northwestern University Medical School, Chicago, Illinois, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01909622100039
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http://dx.doi.org/10.1016/j.jaad.2010.04.004DOI Listing
November 2010

Treatment and management of psoriasis with nail involvement: a focus on biologic therapy.

Dermatology 2010 9;221 Suppl 1:29-42. Epub 2010 Aug 9.

Queen Elizabeth II Health Sciences Centre, Dalhousie University, 1278 University Avenue, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1159/000316179DOI Listing
November 2010

Biologics in the treatment of psoriasis: clinical and economic overview.

J Cutan Med Surg 2009 Sep-Oct;13 Suppl 2:S49-57

Hôpital Hôtel-Dieu de Québec and Centre Dermatologique du Québec Métropolitan, Quebec City, QC.

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http://journals.sagepub.com/doi/ 10.2310/7750.2009.00021
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http://dx.doi.org/10.2310/7750.2009.00021DOI Listing
January 2010

Safety of conventional systemic agents and biologic agents in the treatment of psoriasis.

J Cutan Med Surg 2009 Sep-Oct;13 Suppl 2:S67-76

Innovaderm Research, Montreal, QC.

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http://dx.doi.org/10.2310/7750.2009.00023DOI Listing
January 2010

Temporary tattoos to simulate skin disease: report and validation of a novel teaching tool.

Acad Med 2009 Jul;84(7):950-3

Department of Medicine, Division of Dermatology, Dalhousie University, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1097/ACM.0b013e3181a84446DOI Listing
July 2009

Use of anakinra (Kineret) in the treatment of familial cold autoinflammatory syndrome with a 16-month follow-up.

J Cutan Med Surg 2008 Jan-Feb;12(1):8-16

Division of Dermatology and Department of Medicine, Dalhousie University, Halifax, NS, Canada.

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http://dx.doi.org/10.2310/7750.2008.07050DOI Listing
May 2008

An update on the safety and tolerability of pimecrolimus cream 1%: evidence from clinical trials and post-marketing surveillance.

Dermatology 2007 18;215 Suppl 1:27-44. Epub 2007 Dec 18.

Division of Dermatology, Department of Medicine, Dalhousie University, and Queen Elizabeth II Health Science Centre, Halifax, NS, Canada.

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https://www.karger.com/Article/FullText/102118
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http://dx.doi.org/10.1159/000102118DOI Listing
March 2008

Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial.

Arch Dermatol 2008 Feb;144(2):200-7

Clinical Unit for Research Trials in Skin (CURTIS), Massachusetts General and Brigham and Women's Hospitals, Harvard Medical School, 50 Staniford St, No. 246, Boston, MA 02114, USA.

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http://dx.doi.org/10.1001/archdermatol.2007.63DOI Listing
February 2008

Adalimumab therapy for moderate to severe psoriasis: A randomized, controlled phase III trial.

J Am Acad Dermatol 2008 Jan 23;58(1):106-15. Epub 2007 Oct 23.

Division of Dermatology, Baylor Research Institute, University of Texas Southwestern Medical School, 3900 Junius St, 125, Dallas, TX 75246-1613, USA.

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http://dx.doi.org/10.1016/j.jaad.2007.09.010DOI Listing
January 2008

Etanercept treatment for children and adolescents with plaque psoriasis.

N Engl J Med 2008 Jan;358(3):241-51

Children's Memorial Hospital and Department of Dermatology, Northwestern University Medical School, Chicago, IL 60611-2941, USA.

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http://dx.doi.org/10.1056/NEJMoa066886DOI Listing
January 2008

Duration of remission of biologic agents for chronic plaque psoriasis.

J Drugs Dermatol 2007 Dec;6(12):1205-12

Division of Dermatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

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December 2007

Prognostic significance of vascularity in cutaneous melanoma: pilot study using in vivo confocal scanning laser microscopy.

J Cutan Med Surg 2006 May-Jun;10(3):122-7

Division of Anatomical Pathology, Department of Medicine, Dalhousie University, Halifax, NS.

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http://dx.doi.org/10.2310/7750.2006.00031DOI Listing
November 2007

Biologic therapeutics in the treatment of psoriasis. Part 2: practical considerations.

J Cutan Med Surg 2007 Jul-Aug;11(4):145-9

Division of Dermatology, Department of Medicine, Dalhousie University, Halifax, NS.

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http://dx.doi.org/10.2310/7750.2006.00060bDOI Listing
November 2007

Biologic therapeutics in the treatment of psoriasis. Part 1: review.

J Cutan Med Surg 2007 May-Jun;11(3):99-122

Department of Medicine, Dalhousie University, Halifax, NS, Canada.

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http://dx.doi.org/10.2310/7750.2006.00060aDOI Listing
September 2007

Long-term safety and efficacy of 50 mg of etanercept twice weekly in patients with psoriasis.

Arch Dermatol 2007 Jun;143(6):719-26

Department of Dermatology, The University of Texas Health Center at Houston, 6655 Travis, Suite 120, Houston, TX 77030, and Evanston Northwest Healthcare, Skokie, IL, USA.

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http://dx.doi.org/10.1001/archderm.143.6.719DOI Listing
June 2007

Mycosis fungoides presenting as pigmented purpuric dermatitis.

Pediatr Dermatol 2006 Jul-Aug;23(4):350-4

Department of Dermatology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1111/j.1525-1470.2006.00259.xDOI Listing
January 2007

Reflectance-mode confocal microscopy for the diagnosis of sebaceous hyperplasia in vivo.

Arch Dermatol 2007 Jan;143(1):134

Division of Dermatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia.

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http://dx.doi.org/10.1001/archderm.143.1.134DOI Listing
January 2007

Clinical response to adalimumab treatment in patients with moderate to severe psoriasis: double-blind, randomized controlled trial and open-label extension study.

J Am Acad Dermatol 2006 Oct 10;55(4):598-606. Epub 2006 Aug 10.

Division of Dermatology, Evanston Northwestern Healthcare and Northwestern University Feinberg School of Medicine, Skokie, IL 60077, USA.

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http://dx.doi.org/10.1016/j.jaad.2006.05.027DOI Listing
October 2006

Recommendations for incorporating biologicals into management of moderate to severe plaque psoriasis: individualized patient approaches.

J Cutan Med Surg 2006 ;9 Suppl 1:18-25

Queen Elizabeth II Health Science Centre, Dalhousie University, 4195 Dickson Building, B3H 2Y9, Halifax, NS.

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http://dx.doi.org/10.1007/s10227-006-0103-1DOI Listing
September 2006

Efalizumab, a reversible T-cell modulator for psoriasis.

J Cutan Med Surg 2006 ;9 Suppl 1:4-9

Sunnybrook & Women's College Health Sciences Centre, University of Toronto Medical School and Ventana Clinical Research Corp., Toronto, ON.

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http://link.springer.com/10.1007/s10227-006-0101-3
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http://dx.doi.org/10.1007/s10227-006-0101-3DOI Listing
September 2006

In vivo confocal scanning laser microscopy of benign lentigines: comparison to conventional histology and in vivo characteristics of lentigo maligna.

J Am Acad Dermatol 2006 Jul;55(1):88-97

QEII Health Sciences Centre, Division of Dermatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1016/j.jaad.2006.03.009DOI Listing
July 2006

Erdheim-Chester disease of the breast: a case report and review of the literature.

Breast J 2005 Nov-Dec;11(6):462-7

Division of Anatomical Pathology, Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1111/j.1075-122X.2005.00133.xDOI Listing
December 2005

Alefacept: an expert review concerning the treatment of psoriasis.

Expert Opin Pharmacother 2005 Oct;6(13):2327-33

Dalhousie University, Center for Clinical Research, 5820 University Avenue, Halifax, NS, B3H 1V7, Canada.

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http://dx.doi.org/10.1517/14656566.6.13.2327DOI Listing
October 2005

Topical calcineurin inhibitors in the treatment of atopic dermatitis: a meta-analysis of current evidence.

Am J Clin Dermatol 2004 ;5(4):267-79

PharmIdeas Research & Consulting Inc., Oakville, Ontario, Canada.

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http://dx.doi.org/10.2165/00128071-200405040-00006DOI Listing
December 2004

Evaluating psoriasis with Psoriasis Area and Severity Index, Psoriasis Global Assessment, and Lattice System Physician's Global Assessment.

J Am Acad Dermatol 2004 Oct;51(4):563-9

Department of Medicine, Division of Dermatology, Dalhousie University, Halifax, Nova Scotia.

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http://dx.doi.org/10.1016/j.jaad.2004.04.012DOI Listing
October 2004

Pimecrolimus cream 1%: a potential new treatment for chronic hand dermatitis.

Cutis 2004 Jan;73(1):31-8

Division of Dermatology, University of Kansas Medical Center, 4023 Wescoe Pavillion, Kansas City, KS 66160, USA.

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January 2004

Remittive effects of intramuscular alefacept in psoriasis.

J Drugs Dermatol 2003 Dec;2(6):624-8

Loyola University Medical Center, Maywood, Illinois 60153, USA.

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December 2003

In vivo confocal imaging of pigmented eccrine poroma.

Dermatology 2002 ;204(3):185-9

Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA.

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http://dx.doi.org/10.1159/000057879DOI Listing
August 2002

Safety and efficacy of pimecrolimus (ASM 981) cream 1% in the treatment of mild and moderate atopic dermatitis in children and adolescents.

J Am Acad Dermatol 2002 Apr;46(4):495-504

Pediatric and Adolescent Dermatology, Children's Hospital-San Diego, 3020 Children's Way, Mail Code 5092, San Diego, CA 92123, USA.

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http://dx.doi.org/10.1067/mjd.2002.122187DOI Listing
April 2002

Tacrolimus and pimecrolimus: from clever prokaryotes to inhibiting calcineurin and treating atopic dermatitis.

J Am Acad Dermatol 2002 Feb;46(2):228-41

Cutaneous Oncology Unit, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1067/mjd.2002.120942DOI Listing
February 2002