Richard G Carroll

Richard G Carroll

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Richard G Carroll

Richard G Carroll

Publications by authors named "Richard G Carroll"

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Immunometabolism around the Clock.

Trends Mol Med 2019 Jul 29;25(7):612-625. Epub 2019 May 29.

Curtis Clock Laboratory, Molecular and Cellular Therapeutics Department, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Tissue Engineering Research Group, Department of Anatomy, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Advanced Materials Bio-Engineering Research (AMBER) Centre, Trinity College Dublin, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2019.04.013DOI Listing
July 2019

Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.

Proc Natl Acad Sci U S A 2018 09 20;115(36):E8460-E8468. Epub 2018 Aug 20.

Department of Molecular and Cellular Therapeutics, Tissue Engineering Regenerative Group, Royal College of Surgeons in Ireland, Dublin 2, Ireland;

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http://dx.doi.org/10.1073/pnas.1800431115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130388PMC
September 2018

An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation.

J Biol Chem 2018 04 20;293(15):5509-5521. Epub 2018 Feb 20.

From the School of Biochemistry and Immunology, Trinity Biomedical Science Institute, Trinity College, Dublin 2, Ireland,

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http://dx.doi.org/10.1074/jbc.RA118.001921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900750PMC
April 2018

Inflammasome Priming in Sterile Inflammatory Disease.

Trends Mol Med 2017 02 18;23(2):165-180. Epub 2017 Jan 18.

Immunology Catalyst, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK; Department of Medical Biology, University of Melbourne, Parkville 3010, Australia; Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2016.12.007DOI Listing
February 2017

Parkin sensitizes toward apoptosis induced by mitochondrial depolarization through promoting degradation of Mcl-1.

Cell Rep 2014 Nov 13;9(4):1538-53. Epub 2014 Nov 13.

Molecular Cell Biology Laboratory, Department of Genetics, The Smurfit Institute, Trinity College, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.10.046DOI Listing
November 2014

Bcl-2 family proteins participate in mitochondrial quality control by regulating Parkin/PINK1-dependent mitophagy.

Mol Cell 2014 Aug 3;55(3):451-66. Epub 2014 Jul 3.

Molecular Cell Biology Laboratory, Department of Genetics, The Smurfit Institute, Trinity College Dublin, College Green, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.06.001DOI Listing
August 2014

Autophagy in multiple myeloma: what makes you stronger can also kill you.

Cancer Cell 2013 Apr;23(4):425-6

Molecular Cell Biology Laboratory, Department of Genetics, The Smurfit Institute, Trinity College, Dublin 2, Ireland.

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http://dx.doi.org/10.1016/j.ccr.2013.04.001DOI Listing
April 2013

Treatment of advanced leukemia in mice with mRNA engineered T cells.

Hum Gene Ther 2011 Dec 23;22(12):1575-86. Epub 2011 Sep 23.

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1089/hum.2011.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237694PMC
December 2011

Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor.

Cancer Res 2010 Nov 5;70(22):9053-61. Epub 2010 Oct 5.

Abramson Family Cancer Research Institute and Department of Pathology and Laboratory Medicine and Thoracic Oncology Research Laboratory and Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6160, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-2880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982929PMC
November 2010

The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells.

Sci Transl Med 2010 Oct;2(55):55ra78

Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/scitranslmed.3000448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282816PMC
October 2010

A phase I trial of repeated intrapleural adenoviral-mediated interferon-beta gene transfer for mesothelioma and metastatic pleural effusions.

Mol Ther 2010 Apr 12;18(4):852-60. Epub 2010 Jan 12.

Section of Interventional Pulmonology and Thoracic Oncology, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104-4283, USA.

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http://dx.doi.org/10.1038/mt.2009.309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862532PMC
April 2010

Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo.

Mol Ther 2009 Aug 21;17(8):1453-64. Epub 2009 Apr 21.

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104-5160, USA.

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http://dx.doi.org/10.1038/mt.2009.83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805264PMC
August 2009

Constitutive non-canonical NFkappaB signaling in pancreatic cancer cells.

Cancer Biol Ther 2009 Aug 8;8(16):1567-76. Epub 2009 Aug 8.

Department of Animal Biology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910422PMC
http://dx.doi.org/10.4161/cbt.8.16.8961DOI Listing
August 2009

Genetic engineering of T cells for adoptive immunotherapy.

Immunol Res 2008 ;42(1-3):166-81

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania, 421 Curie Blvd-556 BRB II/III, Philadelphia, PA, 19104, USA.

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http://link.springer.com/10.1007/s12026-008-8057-6
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http://dx.doi.org/10.1007/s12026-008-8057-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699549PMC
March 2009

Adoptive immunotherapy: good habits instilled at youth have long-term benefits.

Immunol Res 2008 ;42(1-3):182-96

Abramson Family Cancer Research Institute, University of Pennsylvania, BRB II/III, Room 554, 421 Curie Boulevard, Philadelphia, PA, 19104-6160, USA.

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http://dx.doi.org/10.1007/s12026-008-8070-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809041PMC
March 2009

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor.

Nat Med 2008 Dec 9;14(12):1390-5. Epub 2008 Nov 9.

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6160, USA.

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http://dx.doi.org/10.1038/nm.1779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008216PMC
December 2008

Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha.

J Virol 2008 Nov 3;82(22):11117-28. Epub 2008 Sep 3.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104.

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http://dx.doi.org/10.1128/JVI.01046-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573261PMC
November 2008

CD28 costimulation is essential for human T regulatory expansion and function.

J Immunol 2008 Aug;181(4):2855-68

Department of Pathology and Laboratory Medicine and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556987PMC
http://dx.doi.org/10.4049/jimmunol.181.4.2855DOI Listing
August 2008

Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules.

Mol Ther 2007 May 20;15(5):981-8. Epub 2007 Mar 20.

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104-5160, USA.

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http://dx.doi.org/10.1038/mt.sj.6300134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932757PMC
May 2007

Programming the next generation of dendritic cells.

Mol Ther 2007 May;15(5):846-8

Abramson Family Research Cancer Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.1038/sj.mt.6300166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809055PMC
May 2007

Multiple initial culture conditions enhance the establishment of cell lines from primary ovarian cancer specimens.

In Vitro Cell Dev Biol Anim 2006 Mar-Apr;42(3-4):58-62

Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19104-6160, USA.

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http://dx.doi.org/10.1290/0512084.1DOI Listing
December 2006

Interferon beta adenoviral gene therapy in a patient with ovarian cancer.

Nat Clin Pract Oncol 2006 Nov;3(11):633-9

Thoracic Oncology Research Laboratory, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/ncponc0658DOI Listing
November 2006

Regulatory T cells and cytokines in malignant pleural effusions secondary to mesothelioma and carcinoma.

Cancer Biol Ther 2005 Mar 1;4(3):342-6. Epub 2005 Mar 1.

Thoracic Oncology Research Laboratory, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.4161/cbt.4.3.1644DOI Listing
March 2005

Vascular leukocytes contribute to tumor vascularization.

Blood 2005 Jan 9;105(2):679-81. Epub 2004 Sep 9.

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, USA.

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http://dx.doi.org/10.1182/blood-2004-05-1906DOI Listing
January 2005

TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted T cells specific for autologous tumor in late-stage ovarian cancer patients.

Clin Cancer Res 2003 Apr;9(4):1517-27

Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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April 2003

PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells.

Am J Physiol Lung Cell Mol Physiol 2002 Aug;283(2):L354-63

Pulmonary, Allergy, and Critical Care Division, Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104-6160, USA.

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http://dx.doi.org/10.1152/ajplung.00010.2002DOI Listing
August 2002

Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation.

J Immunol 2002 May;168(9):4272-6

Department of Surgery, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.168.9.4272DOI Listing
May 2002

Tumor-associated macrophages as a source of functional dendritic cells in ovarian cancer patients.

Clin Immunol 2002 Mar;102(3):291-301

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1006/clim.2001.5179DOI Listing
March 2002