Richard G Ball

Richard G Ball

UNVERIFIED PROFILE

Are you Richard G Ball?   Register this Author

Register author
Richard G Ball

Richard G Ball

Publications by authors named "Richard G Ball"

Are you Richard G Ball?   Register this Author

33Publications

1060Reads

10Profile Views

Stereoselective addition of 2-phenyloxazol-4-yl trifluoromethanesulfonate to N-sulfinyl imines: application to the synthesis of the HCV protease inhibitor boceprevir.

J Org Chem 2013 Jan 20;78(2):706-10. Epub 2012 Dec 20.

Department of Process Research, Merck Research Laboratories, Rahway, New Jersey 07065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo301856fDOI Listing
January 2013

Synthesis of antifungal glucan synthase inhibitors from enfumafungin.

J Org Chem 2012 Apr 28;77(7):3297-310. Epub 2012 Mar 28.

Department of Process Research, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065-0900, USA.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/jo300046v
Publisher Site
http://dx.doi.org/10.1021/jo300046vDOI Listing
April 2012

The discovery of potent antagonists of NPBWR1 (GPR7).

Bioorg Med Chem Lett 2012 Jan 8;22(2):1014-8. Epub 2011 Dec 8.

Merck & Co., Inc., Department of Medicinal Chemistry, PO Box 2000, Rahway, NJ 07065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2011.11.126DOI Listing
January 2012

Design and synthesis of conformationally constrained N,N-disubstituted 1,4-diazepanes as potent orexin receptor antagonists.

Bioorg Med Chem Lett 2010 Apr 8;20(7):2311-5. Epub 2010 Feb 8.

Department of Medicinal Chemistry, Merck Research Laboratories, PO Box 4, Sumneytown Pike, West Point, PA 19486, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2010.01.138DOI Listing
April 2010

A cascade approach to cyclic aminonitrones: reaction discovery, mechanism, and scope.

Org Lett 2009 Aug;11(15):3194-7

Department of Process Research, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ol9010147DOI Listing
August 2009

Conformational analysis of N,N-disubstituted-1,4-diazepane orexin receptor antagonists and implications for receptor binding.

Bioorg Med Chem Lett 2009 Jun 14;19(11):2997-3001. Epub 2009 Apr 14.

Department of Medicinal Chemistry, Merck Research Laboratories, West Point, PA 19486, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2009.04.026DOI Listing
June 2009

Diastereoselective Friedel-Crafts alkylation of indoles with chiral alpha-phenyl benzylic cations. Asymmetric synthesis of anti-1,1,2-triarylalkanes.

Org Lett 2008 Jul 19;10(14):3037-40. Epub 2008 Jun 19.

Process Research, Merck Research Laboratories, Rahway, New Jersey 07065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ol800858cDOI Listing
July 2008

Isolation and structure elucidation of parnafungins, antifungal natural products that inhibit mRNA polyadenylation.

J Am Chem Soc 2008 Jun 8;130(22):7060-6. Epub 2008 May 8.

Natural Products Chemistry, Infectious Diseases, and Process Research, Merck Research Laboratories, Merck and Company, P.O. Box 2000, Rahway, New Jersey 07065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja711209pDOI Listing
June 2008

Preparation of 2,5,7-trithiabicyclo[2.2.1]heptane from 1,2-bis-triisopropylsilanylsulfanyl alkenes.

Org Lett 2006 Jan;8(1):59-61

Merck Frosst Canada, Inc., Autoroute Transcanadienne, Kirkland, Québec.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ol0524858DOI Listing
January 2006

Aryl sulfones: a new class of gamma-secretase inhibitors.

Bioorg Med Chem Lett 2005 May;15(10):2685-8

Department of Medicinal Chemistry, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Terlings Park, Eastwick Road, Harlow, Essex CM20 2QR, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2004.12.017DOI Listing
May 2005

Asymmetric synthesis of alpha,alpha-difluoro-beta-amino acid derivatives from enantiomerically pure N-tert-butylsulfinimines.

J Org Chem 2002 Nov;67(23):8276-9

Merck Research Laboratories, West Point, Pennsylvania 19486, and Merck Research Laboratories, Rahway, New Jersey 07065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo0259313DOI Listing
November 2002

Fusidienol A: A Novel Ras Farnesyl-Protein Transferase Inhibitor from Phoma sp.

J Org Chem 1997 Oct;62(21):7485-7488

Natural Products Drug Discovery, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, and Centro de Investigación Básica, Merck Sharp & Dohme de España S. A., Josefa Valcárcel 38, 28027 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo9708304DOI Listing
October 1997

Dipolar Cycloaddition Route to Diverse Analogues of Cocaine: The 6- and 7-Substituted 3-Phenyltropanes.

J Org Chem 1997 Feb;62(3):503-509

Georgetown University Medical Center, Institute for Cognitive and Computational Sciences, 3970 Reservoir Road NW, Washington, DC 20007-2197, and Merck Sharp & Dohme Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo961957gDOI Listing
February 1997

Chemistry and Biology of Cylindrols: Novel Inhibitors of Ras Farnesyl-Protein Transferase from Cylindrocarpon lucidum.

J Org Chem 1996 Nov;61(22):7727-7737

Merck Research Laboratories, P.O. Box 2000 Rahway, New Jersey 07065 and West Point, Pennsylvania 19486 and Centro de Investigación Básica, Merck Sharp & Dohme de España S.A., Josefa Valcárcel 38, 28027, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo961074pDOI Listing
November 1996