Publications by authors named "Richard Frayne"

124Publications

Cerebral atrophy in amyotrophic lateral sclerosis parallels the pathological distribution of TDP43.

Brain Commun 2020 15;2(2):fcaa061. Epub 2020 May 15.

Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta T6G 2E1, Canada.

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May 2020

Involvement of the dentate nucleus in the pathophysiology of amyotrophic lateral sclerosis: A multi-center and multi-modal neuroimaging study.

Neuroimage Clin 2020 16;28:102385. Epub 2020 Aug 16.

Department of Medicine, Divison of Neurology, University of Alberta, Edmonton, Alberta, AB, Canada; Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, AB, Canada. Electronic address:

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August 2020

Age-related differences in cerebral blood flow and cortical thickness with an application to age prediction.

Neurobiol Aging 2020 11 3;95:131-142. Epub 2020 Jul 3.

Department of Radiology, University of Calgary, Calgary, Alberta, Canada; Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada; Healthy Brain Aging Lab, University of Calgary, Calgary, Alberta, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.

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November 2020

Calgary Normative Study: design of a prospective longitudinal study to characterise potential quantitative MR biomarkers of neurodegeneration over the adult lifespan.

BMJ Open 2020 08 13;10(8):e038120. Epub 2020 Aug 13.

Departments of Clinical Neurosciences and Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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August 2020

A prospective harmonized multicenter DTI study of cerebral white matter degeneration in ALS.

Neurology 2020 08 9;95(8):e943-e952. Epub 2020 Jul 9.

From the Division of Neurology (S.K.), Department of Medicine, Neuroscience and Mental Health Institute (S.K., A.I.), and Department of Biomedical Engineering (C.B.), University of Alberta, Edmonton, Canada; Department of Neurology (H.-P.M., J.K.), University of Ulm, Germany; Sunnybrook Health Sciences Centre (L.Z., S.J.G.), University of Toronto, Ontario; Departments of Clinical Neurosciences (L.K., R.F.) and Radiology (R.F.), Hotchkiss Brain Institute, University of Calgary, Alberta; Montreal Neurological Institute and Hospital (A.G.), McGill University, Quebec; and Seaman Family MR Research Centre (R.F.), Foothills Medical Centre, Calgary, Alberta, Canada.

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August 2020

Cerebrovascular reactivity in cerebral amyloid angiopathy, Alzheimer disease, and mild cognitive impairment.

Neurology 2020 09 8;95(10):e1333-e1340. Epub 2020 Jul 8.

From the Department of Clinical Neurosciences (A.R.S., C.R.M., A.Z., A.C., A.A.-V., R.S., C.Z., R.B.S., R.F., B.G.G., E.E.S), Hotchkiss Brain Institute (R.F., B.G.G., E.E.S), Department of Community Health Sciences (C.Z., E.E.S), and Department of Radiology (R.F., B.G.G., E.E.S), University of Calgary, Alberta; Faculty of Medicine (I.C.), University of Toronto, Ontario; and Seaman Family MR Research Centre (C.R.M., R.F., B.G.G.), Foothills Medical Centre, Calgary, Alberta, Canada

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September 2020

Dual-domain cascade of U-nets for multi-channel magnetic resonance image reconstruction.

Magn Reson Imaging 2020 09 17;71:140-153. Epub 2020 Jun 17.

Radiology and Clinical Neuroscience, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada; Seaman Family MR Research Centre, Foothills Medical Center, Calgary, AB, Canada; Calgary Image Processing and Analysis Center (CIPAC), Foothills Medical Centre, Calgary, AB, Canada.

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September 2020

Cross-sectional and longitudinal differences in peak skeletonized white matter mean diffusivity in cerebral amyloid angiopathy.

Neuroimage Clin 2020 26;27:102280. Epub 2020 May 26.

Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Seaman Family MR Research Centre, Foothills Medical Centre, Alberta Health Sciences, Calgary, Alberta, Canada.

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May 2020

High-resolution T2-FLAIR and non-contrast CT brain atlas of the elderly.

Sci Data 2020 02 17;7(1):56. Epub 2020 Feb 17.

Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

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February 2020

Cerebral degeneration in amyotrophic lateral sclerosis: A prospective multicenter magnetic resonance spectroscopy study.

Neurol Clin Pract 2019 Oct;9(5):400-407

Faculty of Science (OS); Department of Biomedical Engineering (CH, PS, SK); Neuroscience and Mental Health Institute (SC, DT, SK); Divison of Neurology (DM, CL, SK), Department of Medicine; School of Public Health (DE); University of Alberta, Edmonton, Alberta; Sunnybrook Health Sciences Centre (LZ, AA, SJG), University of Toronto, Toronto, Ontario; Montreal Neurological Institute and Hospital (AG), McGill University, Montreal, Quebec; Departments of Radiology and Clinical Neurosciences (LK, RF), Hotchkiss Brain Institute, University of Calgary; and Seaman Family MR Research Centre (LK, RF), Foothills Medical Centre, Calgary, Alberta, Canada.

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October 2019

Convolutional neural networks for skull-stripping in brain MR imaging using silver standard masks.

Artif Intell Med 2019 07 23;98:48-58. Epub 2019 Jul 23.

Medical Image Computing Laboratory (MICLab), Department of Computer Engineering and Industrial Automation, School of Electrical and Computer Engineering, University of Campinas, Campinas, São Paulo, Brazil.

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July 2019

Automatic identification of atherosclerosis subjects in a heterogeneous MR brain imaging data set.

Magn Reson Imaging 2019 10 19;62:18-27. Epub 2019 Jun 19.

Radiology and Clinical Neuroscience, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada; Seaman Family MR Research Centre, Foothills Medical Center, Calgary, AB, Canada; Calgary Image Processing and Analysis Center (CIPAC), Foothills Medical Centre, Calgary, AB, Canada.

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October 2019

Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations.

Alzheimers Dement 2019 06 25;15(6):840-858. Epub 2019 Apr 25.

Centre for Clinical Brain Science, University of Edinburgh, Edinburgh, UK; Dementia Research Institute, University of Edinburgh, Edinburgh, UK; Edinburgh Imaging, University of Edinburgh, Edinburgh, UK.

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June 2019