Richard F Ambinder

Richard F Ambinder

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Richard F Ambinder

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Allogeneic Haploidentical Blood or Marrow Transplantation with Post-Transplantation Cyclophosphamide in Chronic Lymphocytic Leukemia.

Biol Blood Marrow Transplant 2020 Mar 12;26(3):502-508. Epub 2019 Nov 12.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2019.11.008DOI Listing
March 2020

Kaposi's Sarcoma-Associated Herpesvirus LANA Modulates the Stability of the E3 Ubiquitin Ligase RLIM.

J Virol 2020 Feb 14;94(5). Epub 2020 Feb 14.

Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel

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http://dx.doi.org/10.1128/JVI.01578-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022369PMC
February 2020

Pharmacologic Activation of Lytic Epstein-Barr Virus Gene Expression without Virion Production.

J Virol 2019 Oct 30;93(20). Epub 2019 Sep 30.

Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA

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http://dx.doi.org/10.1128/JVI.00998-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798122PMC
October 2019

Is It Time to Revisit the Role of Allogeneic Transplantation in Lymphoma?

Curr Oncol Rep 2019 Jun 10;21(7):65. Epub 2019 Jun 10.

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Room 244, Bunting-Blaustein Cancer Research Bldg., 1650 Orleans Street, Baltimore, MD, 21231, USA.

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http://dx.doi.org/10.1007/s11912-019-0809-zDOI Listing
June 2019

R-CHOP without radiation in frontline management of primary mediastinal B-cell lymphoma.

Leuk Lymphoma 2019 May 18;60(5):1261-1265. Epub 2019 Jan 18.

a Department of Oncology , Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine , Baltimore , MD , USA.

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http://dx.doi.org/10.1080/10428194.2018.1519812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472975PMC
May 2019

Effect of increased dose of total body irradiation on graft failure associated with HLA-haploidentical transplantation in patients with severe haemoglobinopathies: a prospective clinical trial.

Lancet Haematol 2019 Apr 14;6(4):e183-e193. Epub 2019 Mar 14.

Hematologic Malignancies and Bone Marrow Transplantation Program, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/S2352-3026(19)30031-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506220PMC
April 2019

Epigenomic characterization of a p53-regulated 3p22.2 tumor suppressor that inhibits STAT3 phosphorylation via protein docking and is frequently methylated in esophageal and other carcinomas.

Theranostics 2018 1;8(1):61-77. Epub 2018 Jan 1.

Cancer Epigenetics Laboratory, Department of Clinical Oncology, State Key Laboratory of Oncology in South China, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.7150/thno.20893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743460PMC
November 2018

HIV-Specific T Cells Generated from Naive T Cells Suppress HIV In Vitro and Recognize Wide Epitope Breadths.

Mol Ther 2018 06 12;26(6):1435-1446. Epub 2018 Apr 12.

Center for Cancer and Immunology Research, Children's National Health System, Washington, DC 20010, USA; Cancer Center, Department of Pediatrics, The George Washington University, Washington, DC 20037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986979PMC
June 2018

A viral protein kinase drug target for tumors?

J Clin Invest 2018 06 7;128(6):2197-2198. Epub 2018 May 7.

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http://dx.doi.org/10.1172/JCI121080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983323PMC
June 2018

Resistance Is Futile: Engineering the Adoptive T-Cell Therapies of the Future.

J Clin Oncol 2018 04 24;36(11):1140-1142. Epub 2018 Jan 24.

Eugene Shenderov and Richard F. Ambinder, Johns Hopkins School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2017.76.6618DOI Listing
April 2018

Hodgkin lymphoma: A review and update on recent progress.

CA Cancer J Clin 2018 03 1;68(2):116-132. Epub 2017 Dec 1.

Director, Division of Hematologic Malignancies and Professor of Oncology, Departments of Medicine and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.3322/caac.21438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842098PMC
March 2018

Treatment of HIV-Associated Lymphomas: The Latest Approaches for Optimizing Outcomes.

Oncology (Williston Park) 2017 12;31(12):872-7, 884

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December 2017

Major Histocompatibility Mismatch and Donor Choice for Second Allogeneic Bone Marrow Transplantation.

Biol Blood Marrow Transplant 2017 Nov 25;23(11):1887-1894. Epub 2017 Jul 25.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Division of Hematologic Malignancies, Bunting Blaustein Cancer Research Bldg., 1650 Orleans Street, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881910PMC
November 2017

Drug Modulators of B Cell Signaling Pathways and Epstein-Barr Virus Lytic Activation.

J Virol 2017 08 27;91(16). Epub 2017 Jul 27.

Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA

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http://dx.doi.org/10.1128/JVI.00747-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533897PMC
August 2017

Plasma Epstein-Barr Virus DNA for Screening.

N Engl J Med 2017 08;377(6):584-585

From Johns Hopkins School of Medicine, Baltimore.

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http://dx.doi.org/10.1056/NEJMe1706815DOI Listing
August 2017

Elevated Serum Levels of sCD30 and IL6 and Detectable IL10 Precede Classical Hodgkin Lymphoma Diagnosis.

Cancer Epidemiol Biomarkers Prev 2017 07 24;26(7):1114-1123. Epub 2017 Mar 24.

Department of Obstetrics & Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-1012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511544PMC
July 2017

Initial Experience with Tositumomab and I-131-Labeled Tositumomab for Treatment of Relapsed/Refractory Hodgkin Lymphoma.

Mol Imaging Biol 2017 06;19(3):429-436

Division of Nuclear Medicine, Department of Radiology, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/s11307-016-1019-9DOI Listing
June 2017

EBV, an inhibited receptor kinase, and lymphoma.

Blood 2016 09;128(12):1542-3

JOHNS HOPKINS SCHOOL OF MEDICINE.

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http://dx.doi.org/10.1182/blood-2016-08-724955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034736PMC
September 2016

Brief Report: A Phase 1b/Pharmacokinetic Trial of PTC299, a Novel PostTranscriptional VEGF Inhibitor, for AIDS-Related Kaposi's Sarcoma: AIDS Malignancy Consortium Trial 059.

J Acquir Immune Defic Syndr 2016 May;72(1):52-7

*Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA;†Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA;‡Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR;§The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD;‖Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC;¶Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC; and#Division of Medical Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1097/QAI.0000000000000918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838493PMC
May 2016

Epigenetic inactivation of the CpG demethylase TET1 as a DNA methylation feedback loop in human cancers.

Sci Rep 2016 05 26;6:26591. Epub 2016 May 26.

Cancer Epigenetics Laboratory, Department of Clinical Oncology, State Key Laboratory of Oncology in South China, Sir YK Pao Center for Cancer, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1038/srep26591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880909PMC
May 2016

Functionally Active HIV-Specific T Cells that Target Gag and Nef Can Be Expanded from Virus-Naïve Donors and Target a Range of Viral Epitopes: Implications for a Cure Strategy after Allogeneic Hematopoietic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2016 Mar 22;22(3):536-41. Epub 2015 Dec 22.

Program for Cell Enhancement and Technologies for Immunotherapy, Sheikh Zayed Institute for Pediatric Surgical Innovation, and Center for Cancer and Immunology Research, Children's National Health System, Washington, DC. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2015.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753092PMC
March 2016

Predictive Value of Cytokines and Immune Activation Biomarkers in AIDS-Related Non-Hodgkin Lymphoma Treated with Rituximab plus Infusional EPOCH (AMC-034 trial).

Clin Cancer Res 2016 Jan 17;22(2):328-36. Epub 2015 Sep 17.

Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, California. Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California. UCLA AIDS Institute, Los Angeles, California. Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, California. Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-14-0466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715998PMC
January 2016

Family history of cancer and risk of pediatric and adolescent Hodgkin lymphoma: A Children's Oncology Group study.

Int J Cancer 2015 Nov 19;137(9):2163-74. Epub 2015 May 19.

Division of Epidemiology, Biostatistics, and Preventive Medicine, Department of Internal Medicine, University of New Mexico, Albuquerque, NM.

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http://dx.doi.org/10.1002/ijc.29589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833396PMC
November 2015

Infectious, autoimmune and allergic diseases and risk of Hodgkin lymphoma in children and adolescents: a Children's Oncology Group study.

Int J Cancer 2014 Sep 18;135(6):1454-69. Epub 2014 Mar 18.

Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota; University of Minnesota Masonic Cancer Center, Minneapolis, Minnesota.

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http://dx.doi.org/10.1002/ijc.28785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107091PMC
September 2014

Epigenetic identification of receptor tyrosine kinase-like orphan receptor 2 as a functional tumor suppressor inhibiting β-catenin and AKT signaling but frequently methylated in common carcinomas.

Cell Mol Life Sci 2014 Jun 25;71(11):2179-92. Epub 2013 Oct 25.

Cancer Epigenetics Laboratory, Department of Clinical Oncology, State Key Laboratory of Oncology in South China, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong and CUHK Shenzhen Research Institute, Shatin, Hong Kong.

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http://link.springer.com/content/pdf/10.1007/s00018-013-1485
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http://link.springer.com/10.1007/s00018-013-1485-z
Publisher Site
http://dx.doi.org/10.1007/s00018-013-1485-zDOI Listing
June 2014

Active idiotypic vaccination versus control immunotherapy for follicular lymphoma.

J Clin Oncol 2014 Jun 5;32(17):1797-803. Epub 2014 May 5.

Ronald Levy, Andrew J. Gentles, Chih Long Liu, Robert Tibshirani, and Ash A. Alizadeh, Stanford University Medical Center, Palo Alto; Christos E. Emmanouilides and John M. Timmerman, University of California Los Angeles Medical Center, Los Angeles; Lori A. Kunkel, Diane E. Ingolia, and Dan W. Denney Jr, Genitope, Fremont, CA; Kristen N. Ganjoo and Michael J. Robertson, Indiana University Medical Center, Indianapolis, IN; John P. Leonard, Weill Medical College of Cornell University, New York, NY; Julie M. Vose, University of Nebraska Medical Center, Omaha, NE; Ian W. Flinn and Richard F. Ambinder, Johns Hopkins University Oncology Center, Baltimore, MD; Joseph M. Connors, British Columbia Cancer Agency Centre for Lymphoid Cancer, Vancouver, British Columbia; Neil L. Berinstein, Toronto-Sunnybrook Regional Cancer Centre, Toronto, Ontario; Andrew R. Belch, Cross Cancer Institute, Edmonton, Alberta, Canada; Nancy L. Bartlett, Washington University School of Medicine, St Louis, MO; Craig Nichols, Oregon Health Science University, Portland, OR; Stephanie A. Gregory, Rush University Medical Center, Chicago, IL; Brian K. Link, University of Iowa Hospitals and Clinics, Iowa City, IA; David J. Inwards, Mayo Clinic, Rochester, MN; Arnold S. Freedman, Dana-Farber Cancer Institute, Boston, MA; and Jeffrey V. Matous, Rocky Mountain Cancer Centers, Denver, CO.

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http://dx.doi.org/10.1200/JCO.2012.43.9273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039868PMC
June 2014

Nelfinavir inhibits maturation and export of herpes simplex virus 1.

J Virol 2014 May 26;88(10):5455-61. Epub 2014 Feb 26.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1128/JVI.03790-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019105PMC
May 2014

HHV-8-positive and EBV-positive intravascular lymphoma: an unusual presentation of extracavitary primary effusion lymphoma.

Am J Surg Pathol 2014 Mar;38(3):426-32

Departments of *Pathology ‡Radiology §Dermatology †Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, Baltimore, MD.

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http://dx.doi.org/10.1097/PAS.0000000000000128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934643PMC
March 2014

Serum levels of cytokines and biomarkers for inflammation and immune activation, and HIV-associated non-Hodgkin B-cell lymphoma risk.

Cancer Epidemiol Biomarkers Prev 2014 Feb 12;23(2):343-9. Epub 2013 Nov 12.

Authors' Affiliations: University of California Los Angeles (UCLA) AIDS Institute, Jonsson Comprehensive Cancer Center at UCLA, Departments of Obstetrics and Gynecology, Psychiatry and Biobehavioral Sciences, and Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Department of Epidemiology, UCLA School of Public Health, Los Angeles, California; Departments of Epidemiology and Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health and Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; and Department of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948172PMC
February 2014

Old variables, new value: a refined IPI for DLBCL.

Blood 2014 Feb;123(6):800-1

JOHNS HOPKINS UNIVERSITY.

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http://dx.doi.org/10.1182/blood-2013-12-540914DOI Listing
February 2014

Bortezomib salvage therapy in refractory acute adult T-cell leukemia/lymphoma.

Leuk Lymphoma 2013 Nov 19;54(11):2563-4. Epub 2013 Apr 19.

Myeloid Malignancies Section, National Heart, Lung and Blood Institute , Bethesda, MD , USA.

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http://dx.doi.org/10.3109/10428194.2013.780289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154876PMC
November 2013

Insights into the broad cellular effects of nelfinavir and the HIV protease inhibitors supporting their role in cancer treatment and prevention.

Curr Opin Oncol 2013 Sep;25(5):495-502

University of British Columbia, Child & Family Research Institute, Room A5-147, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada.

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http://dx.doi.org/10.1097/CCO.0b013e328363dfeeDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029099PMC
September 2013

EBV-related lymphomas: new approaches to treatment.

Curr Treat Options Oncol 2013 Jun;14(2):224-36

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, Cancer Research Building 1, Room 389, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1007/s11864-013-0231-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670765PMC
June 2013

Hematopoietic stem cell transplantation in HIV-1-infected individuals: clinical challenges and the potential for viral eradication.

Curr Opin Oncol 2013 Mar;25(2):180-6

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21087, USA.

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http://dx.doi.org/10.1097/CCO.0b013e32835d814aDOI Listing
March 2013

Atypical prediagnosis Epstein-Barr virus serology restricted to EBV-positive Hodgkin lymphoma.

Blood 2012 Nov 12;120(18):3750-5. Epub 2012 Sep 12.

Department of Epidemiology, Preventive Medicine Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910-7500, USA.

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http://dx.doi.org/10.1182/blood-2011-12-390823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488887PMC
November 2012

CpG methylation as a tool to characterize cell-free Kaposi sarcoma herpesvirus DNA.

J Infect Dis 2012 Apr 22;205(7):1095-9. Epub 2012 Feb 22.

Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1093/infdis/jis032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295606PMC
April 2012

Use of antineoplastic agents in patients with cancer who have HIV/AIDS.

Lancet Oncol 2011 Sep 12;12(9):905-12. Epub 2011 May 12.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1016/S1470-2045(11)70056-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343721PMC
September 2011

Bortezomib induction of C/EBPβ mediates Epstein-Barr virus lytic activation in Burkitt lymphoma.

Blood 2011 Jun 29;117(23):6297-303. Epub 2011 Mar 29.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1182/blood-2011-01-332379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122948PMC
June 2011

When differentiation goes viral.

Blood 2011 Jun;117(22):5790-1

Johns Hopkins School of Medicine.

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http://dx.doi.org/10.1182/blood-2011-04-344135DOI Listing
June 2011

IgH gene rearrangements as plasma biomarkers in Non- Hodgkin's lymphoma patients.

Oncotarget 2011 Mar;2(3):178-85

The Ludwig Center for Cancer Genetics and Therapeutics and Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260819PMC
http://dx.doi.org/10.18632/oncotarget.235DOI Listing
March 2011