Richard Edmondson

Richard Edmondson

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Richard Edmondson

Richard Edmondson

Publications by authors named "Richard Edmondson"

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Epithelial ovarian cancer risk: A review of the current genetic landscape.

Clin Genet 2020 Jan 29;97(1):54-63. Epub 2019 May 29.

Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1111/cge.13566DOI Listing
January 2020

Decision-Making in Gynaecological Oncology Multidisciplinary Team Meetings: A Cross-Sectional, Observational Study of Ovarian Cancer Cases.

Oncol Res Treat 2019 Nov 19:1-6. Epub 2019 Nov 19.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom,

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http://dx.doi.org/10.1159/000504260DOI Listing
November 2019

Prevalence of germline pathogenic variants in sequential epithelial ovarian cancer cases.

J Med Genet 2019 05 25;56(5):301-307. Epub 2019 Jan 25.

Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1136/jmedgenet-2018-105792DOI Listing
May 2019

Ex vivo expanded tumour-infiltrating lymphocytes from ovarian cancer patients release anti-tumour cytokines in response to autologous primary ovarian cancer cells.

Cancer Immunol Immunother 2018 Oct 23;67(10):1519-1531. Epub 2018 Jul 23.

Gynaecological Oncology, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/s00262-018-2211-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182400PMC
October 2018

DNA damage repair in ovarian cancer: unlocking the heterogeneity.

J Ovarian Res 2018 Jun 20;11(1):50. Epub 2018 Jun 20.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.

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http://dx.doi.org/10.1186/s13048-018-0424-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011341PMC
June 2018

PARP inhibitors in platinum-sensitive high-grade serous ovarian cancer.

Cancer Chemother Pharmacol 2018 04 20;81(4):647-658. Epub 2018 Feb 20.

Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1007/s00280-018-3532-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854713PMC
April 2018

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer.

Cochrane Database Syst Rev 2018 02 1;2:CD012513. Epub 2018 Feb 1.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 5th Floor - Research, St Mary's Hospital, Manchester, UK, M13 9WL.

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http://dx.doi.org/10.1002/14651858.CD012513.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491136PMC
February 2018

The unrecognized burden of cardiovascular risk factors in women newly diagnosed with endometrial cancer: A prospective case control study.

Gynecol Oncol 2018 01 24;148(1):154-160. Epub 2017 Nov 24.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, United Kingdom; Department of Obstetrics and Gynaecology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258173152
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http://dx.doi.org/10.1016/j.ygyno.2017.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562057PMC
January 2018

Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer.

Oncotarget 2017 Sep 15;8(41):69779-69796. Epub 2017 Jul 15.

Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne NE2 4HH, United Kingdom.

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http://www.oncotarget.com/fulltext/19266
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http://dx.doi.org/10.18632/oncotarget.19266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642516PMC
September 2017

Ovarian Cancers Harbor Defects in Nonhomologous End Joining Resulting in Resistance to Rucaparib.

Clin Cancer Res 2017 04 4;23(8):2050-2060. Epub 2016 Oct 4.

Faculty Institute for Cancer Studies, University of Manchester, St Mary's Hospital, Oxford Road, Manchester, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393437PMC
April 2017

Functional characterisation of a novel ovarian cancer cell line, NUOC-1.

Oncotarget 2017 Apr;8(16):26832-26844

Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.

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http://dx.doi.org/10.18632/oncotarget.15821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432300PMC
April 2017

Ki-67 in endometrial cancer: scoring optimization and prognostic relevance for window studies.

Mod Pathol 2017 03 2;30(3):459-468. Epub 2016 Dec 2.

Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.

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http://dx.doi.org/10.1038/modpathol.2016.203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337118PMC
March 2017

Working together to shape the endometrial cancer research agenda: The top ten unanswered research questions.

Gynecol Oncol 2016 Nov 1;143(2):287-293. Epub 2016 Sep 1.

Gynaecological Oncology Research Group, Institute of Cancer Sciences, Faculty of Medical and Human Sciences, University of Manchester, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK; Womb Cancer Alliance Priority Setting Partnership Study Group, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2016.08.333DOI Listing
November 2016

Advanced Ovarian Cancer Displays Functional Intratumor Heterogeneity That Correlates to Ex Vivo Drug Sensitivity.

Int J Gynecol Cancer 2016 07;26(6):1004-11

*Northern Gynaecological Oncology Centre, Queen Elizabeth Hospital, Gateshead, United Kingdom; †Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK; and ‡Faculty Institute for Cancer Studies, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.

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http://dx.doi.org/10.1097/IGC.0000000000000745DOI Listing
July 2016

Advanced Ovarian Cancer Displays Functional Intratumor Heterogeneity That Correlates to Ex Vivo Drug Sensitivity.

Int J Gynecol Cancer 2016 Jul;26(6):1004-1011

Northern Gynaecological Oncology Centre, Queen Elizabeth Hospital, Gateshead, United Kingdom.

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http://dx.doi.org/10.1097/IGC.0000000000000745DOI Listing
July 2016

Phosphatase and Tensin Homolog Is a Potential Target for Ovarian Cancer Sensitization to Cytotoxic Agents.

Int J Gynecol Cancer 2016 May;26(4):632-9

*Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne; †Northern Gynaecological Oncology Centre, Queen Elizabeth Hospital, Gateshead; and ‡Faculty Institute for Cancer Studies, University of Manchester, St Marys Hospital, Manchester, UK.

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http://dx.doi.org/10.1097/IGC.0000000000000657DOI Listing
May 2016

Hormone replacement therapy after treatment for a gynaecological malignancy.

Curr Opin Obstet Gynecol 2016 Feb;28(1):32-41

aNorthern Gynaecological Oncology Centre, Queen Elizabeth Hospital, Sheriff Hill, Gateshead bNew Croft Centre, Market Street, Newcastle Upon Tyne cFaculty Institute for Cancer Studies, University of Manchester, St Mary's Hospital, Manchester, UK.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/GCO.0000000000000238DOI Listing
February 2016

Gynecologic Cancer InterGroup (GCIG) Endometrial Cancer Clinical Trials Planning Meeting: taking endometrial cancer trials into the translational era.

Int J Gynecol Cancer 2013 Oct;23(8):1528-34

*Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands; †Institute of Cancer Sciences, University of Manchester, United Kingdom; ‡Division of Hematology and Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, MA; §Division of Gynaecology, European Institute of Oncology, Milan, Italy; ∥Department of Gynecologic Oncology and Reproductive Medicine, MD Anderson Cancer Center, Houston, TX; ¶Department of Clinical Oncology, Barts Health NHS Trust, London, United Kingdom; #Department of Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY; **Department of Gynaecology, Newcastle University and Northern Institute for Cancer Research, Newcastle upon Tyne, United Kingdom; ††Department of Obstetrics and Gynecology, College of Medicine, Ohio State University, Columbus, OH; ‡‡Department of Gynaecologic Oncology, Royal Women's Hospital, and Melbourne University Dept of Obstetrics and Gynaecology, Australia; §§Department of Obstetrics and Gynecology, Haukeland University Hospital; and Department of Clinical Medicine, University of Bergen, Norway; and ∥∥Department of Radiation Oncology, Sunnybrook Cancer Center, Toronto, Canada.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/IGC.0b013e3182a26edbDOI Listing
October 2013

What do we do with all the false-positive CA125s?

J Fam Plann Reprod Health Care 2013 Jul 24;39(3):160-2. Epub 2013 May 24.

Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1136/jfprhc-2013-100591DOI Listing
July 2013

Androgen receptor expression is a biological marker for androgen sensitivity in high grade serous epithelial ovarian cancer.

Gynecol Oncol 2012 Jan 15;124(1):142-7. Epub 2011 Oct 15.

Northern Gynaecological Oncology Centre, Queen Elizabeth Hospital, Gateshead, UK.

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http://dx.doi.org/10.1016/j.ygyno.2011.09.004DOI Listing
January 2012

The role of hormonal therapy in gynecological cancers-current status and future directions.

Int J Gynecol Cancer 2011 Oct;21(7):1328-33

NHMRC Clinical Trials Centre, University of Sydney, Australia.

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http://dx.doi.org/10.1097/IGC.0b013e31821d6021DOI Listing
October 2011

Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2.

J Natl Cancer Inst 2011 Feb 23;103(4):334-46. Epub 2010 Dec 23.

Northern Institute for Cancer Research, University of Newcastle Upon Tyne, Medical School, Newcastle Upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1093/jnci/djq509DOI Listing
February 2011

Lower-limb lymphedema and vulval cancer: feasibility of prophylactic compression garments and validation of leg volume measurement.

Int J Gynecol Cancer 2009 Dec;19(9):1649-54

Academic Unit of Obstetrics and Gynaecology, St Mary's Hospital, The University of Manchester, Manchester, United Kingdom.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1111/IGC.0b013e3181a8446aDOI Listing
December 2009

3beta-Hydroxysteroid dehydrogenases and pre-receptor steroid metabolism in the human ovarian surface epithelium.

Mol Cell Endocrinol 2009 Mar 20;301(1-2):65-73. Epub 2008 Aug 20.

Reproductive and Developmental Sciences, Centre for Reproductive Biology, University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.

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http://dx.doi.org/10.1016/j.mce.2008.08.010DOI Listing
March 2009

The post-LLETZ cervical smear: influence of time interval from LLETZ.

Acta Cytol 2006 Jul-Aug;50(4):415-7

Gynaecology Department, Stepping Hill Hospital, Manchester, UK.

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http://dx.doi.org/10.1159/000325984DOI Listing
September 2006

Ligands to FGF receptor 2-IIIb induce proliferation, motility, protection from cell death and cytoskeletal rearrangements in epithelial ovarian cancer cell lines.

Growth Factors 2006 Mar;24(1):45-53

Northern Institute for Cancer Research and School of Surgical and Reproductive Sciences, Faculty of Medical Sciences, University of Newcastle, Newcastle-upon-Tyne, UK.

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http://www.tandfonline.com/doi/full/10.1080/0897719050036169
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http://dx.doi.org/10.1080/08977190500361697DOI Listing
March 2006