Richard E Straub

Richard E Straub

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Richard E Straub

Richard E Straub

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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

Am J Hum Genet 2019 Aug;105(2):334-350

Division of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.06.012DOI Listing
August 2019

Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia.

Neuron 2019 Jul 4;103(2):203-216.e8. Epub 2019 Jun 4.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD 21205, USA; Center for Computational Biology, Johns Hopkins University, Baltimore, MD 21205, USA; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.05.013DOI Listing
July 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2019 May 1;10(1):2068. Epub 2019 May 1.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-019-10160-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494826PMC
May 2019

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

Authors:
Jeanne E Savage Philip R Jansen Sven Stringer Kyoko Watanabe Julien Bryois Christiaan A de Leeuw Mats Nagel Swapnil Awasthi Peter B Barr Jonathan R I Coleman Katrina L Grasby Anke R Hammerschlag Jakob A Kaminski Robert Karlsson Eva Krapohl Max Lam Marianne Nygaard Chandra A Reynolds Joey W Trampush Hannah Young Delilah Zabaneh Sara Hägg Narelle K Hansell Ida K Karlsson Sten Linnarsson Grant W Montgomery Ana B Muñoz-Manchado Erin B Quinlan Gunter Schumann Nathan G Skene Bradley T Webb Tonya White Dan E Arking Dimitrios Avramopoulos Robert M Bilder Panos Bitsios Katherine E Burdick Tyrone D Cannon Ornit Chiba-Falek Andrea Christoforou Elizabeth T Cirulli Eliza Congdon Aiden Corvin Gail Davies Ian J Deary Pamela DeRosse Dwight Dickinson Srdjan Djurovic Gary Donohoe Emily Drabant Conley Johan G Eriksson Thomas Espeseth Nelson A Freimer Stella Giakoumaki Ina Giegling Michael Gill David C Glahn Ahmad R Hariri Alex Hatzimanolis Matthew C Keller Emma Knowles Deborah Koltai Bettina Konte Jari Lahti Stephanie Le Hellard Todd Lencz David C Liewald Edythe London Astri J Lundervold Anil K Malhotra Ingrid Melle Derek Morris Anna C Need William Ollier Aarno Palotie Antony Payton Neil Pendleton Russell A Poldrack Katri Räikkönen Ivar Reinvang Panos Roussos Dan Rujescu Fred W Sabb Matthew A Scult Olav B Smeland Nikolaos Smyrnis John M Starr Vidar M Steen Nikos C Stefanis Richard E Straub Kjetil Sundet Henning Tiemeier Aristotle N Voineskos Daniel R Weinberger Elisabeth Widen Jin Yu Goncalo Abecasis Ole A Andreassen Gerome Breen Lene Christiansen Birgit Debrabant Danielle M Dick Andreas Heinz Jens Hjerling-Leffler M Arfan Ikram Kenneth S Kendler Nicholas G Martin Sarah E Medland Nancy L Pedersen Robert Plomin Tinca J C Polderman Stephan Ripke Sophie van der Sluis Patrick F Sullivan Scott I Vrieze Margaret J Wright Danielle Posthuma

Nat Genet 2018 07 25;50(7):912-919. Epub 2018 Jun 25.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41588-018-0152-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411041PMC
July 2018

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2018 05 29;9(1):2098. Epub 2018 May 29.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-018-04362-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974083PMC
May 2018

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.

Cell Rep 2017 Nov;21(9):2597-2613

Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA; Department of Psychiatry, Hofstra Northwell School of Medicine, Hempstead, NY, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789458PMC
November 2017

qSVA framework for RNA quality correction in differential expression analysis.

Proc Natl Acad Sci U S A 2017 07 20;114(27):7130-7135. Epub 2017 Jun 20.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD 21205.

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http://dx.doi.org/10.1073/pnas.1617384114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502589PMC
July 2017

Differential effects of common variants in SCN2A on general cognitive ability, brain physiology, and messenger RNA expression in schizophrenia cases and control individuals.

JAMA Psychiatry 2014 Jun;71(6):647-56

Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland2Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, Maryland8Depar.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160812PMC
June 2014

Incomplete penetrance of NRXN1 deletions in families with schizophrenia.

Schizophr Res 2014 May 26;155(1-3):1-7. Epub 2014 Mar 26.

Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, 855 North Wolfe St, Suite 300, Baltimore, MD 21205, United States. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2014.02.023DOI Listing
May 2014

Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia.

J Neurosci 2014 Apr;34(14):4929-40

Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, Division of Intramural Research Programs, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, Department of Psychiatry, Hiroshima City Hospital, Hiroshima City, Hiroshima Prefecture, 730-8518, Japan, Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205, Neurodevelopmental and Neuropsychiatric Genetics Laboratory, Departments of Psychiatry and Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, Colorado 80045, and Departments of Psychiatry, Neurology, Neuroscience and the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.1423-13.2
Publisher Site
http://dx.doi.org/10.1523/JNEUROSCI.1423-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972720PMC
April 2014

Variation in psychosis gene ZNF804A is associated with a refined schizotypy phenotype but not neurocognitive performance in a large young male population.

Schizophr Bull 2013 Nov 15;39(6):1252-60. Epub 2012 Nov 15.

*To whom correspondence should be addressed; Centre for Clinical Research in Neuropsychiatry, School of Psychiatry and Clinical Neurosciences, The University of Western Australia and North Metropolitan Health Service-Mental Health, Gascoyne House, John XXIII Avenue, Mt Claremont, WA 6010, Perth, Australia; tel: (08)9347-6439, fax: (08)9384-5128, e-mail:

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http://dx.doi.org/10.1093/schbul/sbs110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796069PMC
November 2013

Analysis of copy number variations in brain DNA from patients with schizophrenia and other psychiatric disorders.

Biol Psychiatry 2012 Oct 15;72(8):651-4. Epub 2012 Jul 15.

Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.biopsych.2012.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3456994PMC
October 2012

Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia.

J Neurosci 2011 Jul;31(30):11088-95

Section on Neuropathology, Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1234-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758549PMC
July 2011

Evidence of sex-modulated association of ZNF804A with schizophrenia.

Biol Psychiatry 2011 May 24;69(10):914-7. Epub 2011 Feb 24.

Genes, Cognition and Psychosis Program and Clinical, Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1016/j.biopsych.2011.01.003DOI Listing
May 2011

Genetic variation in CACNA1C affects brain circuitries related to mental illness.

Arch Gen Psychiatry 2010 Sep;67(9):939-45

Genes, Cognition, and Psychosis Program, Division of Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1001/archgenpsychiatry.2010.96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282053PMC
September 2010

Progranulin (GRN) in two siblings of a Latino family and in other patients with schizophrenia.

Neurocase 2010 Jun 18;16(3):273-9. Epub 2010 Jan 18.

Department of Internal Medicine, Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.

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http://dx.doi.org/10.1080/13554790903456209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895558PMC
June 2010

Genetic variation in FGF20 modulates hippocampal biology.

J Neurosci 2010 Apr;30(17):5992-7

Clinical Brain Disorder Branch, Genes, Cognition, and Psychosis Program, National Institutes of Health-National Institute of Mental Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5773-09.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909689PMC
April 2010

Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function.

PLoS Genet 2008 Nov 7;4(11):e1000252. Epub 2008 Nov 7.

Department of Health and Human Services, Unit of Systems Neuroscience in Psychiatry, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1000252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573019PMC
November 2008

Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans.

J Clin Invest 2008 Jun;118(6):2200-8

Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, Division of Intramural Research Programs, National Institute of Mental Health, NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1172/JCI34725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391279PMC
June 2008

Genetic variation in catechol-O-methyltransferase: effects on working memory in schizophrenic patients, their siblings, and healthy controls.

Biol Psychiatry 2008 Jan 20;63(1):72-9. Epub 2007 Aug 20.

Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/j.biopsych.2007.03.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708610PMC
January 2008

Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients.

Schizophr Res 2008 Jan 24;98(1-3):105-10. Epub 2007 Oct 24.

MiNDS Unit of the Clinical Brain Disorders Branch, IRP, NIMH, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.schres.2007.05.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246024PMC
January 2008

Evidence that the BLOC-1 protein dysbindin modulates dopamine D2 receptor internalization and signaling but not D1 internalization.

J Neurosci 2007 Nov;27(45):12390-5

Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institutes of Health, United States Department of Health and Human Services, Bethesda, Maryland 20892-1385, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1689-07.2007DOI Listing
November 2007

Risk for premenstrual dysphoric disorder is associated with genetic variation in ESR1, the estrogen receptor alpha gene.

Biol Psychiatry 2007 Oct 27;62(8):925-33. Epub 2007 Jun 27.

Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000632230601558
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http://dx.doi.org/10.1016/j.biopsych.2006.12.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762203PMC
October 2007

A genome-wide scan for modifier loci in schizophrenia.

Am J Med Genet B Neuropsychiatr Genet 2007 Jul;144B(5):589-95

Washington VA Medical Center, Washington, DC 20422, USA.

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http://dx.doi.org/10.1002/ajmg.b.30442DOI Listing
July 2007

Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition.

J Clin Invest 2007 Mar 8;117(3):672-82. Epub 2007 Feb 8.

Unit for Systems Neuroscience in Psychiatry, Neuroimaging Core Facility, and Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute for Mental Health (NIMH), NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1172/JCI30413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784004PMC
March 2007

Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia.

Hum Genet 2007 Feb 28;120(6):889-906. Epub 2006 Sep 28.

Clinical Brain Disorders Branch, National Institute of Mental Health, National Institute of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s00439-006-0257-3DOI Listing
February 2007

Allelic variation in RGS4 impacts functional and structural connectivity in the human brain.

J Neurosci 2007 Feb;27(7):1584-93

Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892-1364, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5112-06.2007DOI Listing
February 2007

The G72/G30 gene complex and cognitive abnormalities in schizophrenia.

Neuropsychopharmacology 2006 Sep 22;31(9):2022-32. Epub 2006 Mar 22.

Clinical Brain Disorders Branch, IRP, NIMH, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/sj.npp.1301049DOI Listing
September 2006

RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity.

Hum Mol Genet 2006 Sep 11;15(18):2804-12. Epub 2006 Aug 11.

Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute for Mental Health, NIH, DHHS, Bethesda, MD 20892-1385, USA.

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http://dx.doi.org/10.1093/hmg/ddl222DOI Listing
September 2006

Schizophrenia genes - famine to feast.

Biol Psychiatry 2006 Jul;60(2):81-3

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http://dx.doi.org/10.1016/j.biopsych.2006.06.002DOI Listing
July 2006

Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs.

Hum Mol Genet 2006 Apr 1;15(8):1245-58. Epub 2006 Mar 1.

Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.

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http://hmg.oxfordjournals.org/content/15/8/1245.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddl040
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http://dx.doi.org/10.1093/hmg/ddl040DOI Listing
April 2006

Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate measures in the dorsolateral prefrontal cortex.

Am J Psychiatry 2006 Apr;163(4):740-2

Genes and Cognition Program, Clinical Brain Disorders Branch, Intramural Research Program, Bldg. 10, Rm. 4S235, 10 Center Dr., NIMH, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1176/appi.ajp.163.4.740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855226PMC
April 2006

Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia.

Proc Natl Acad Sci U S A 2005 Jun 6;102(24):8627-32. Epub 2005 Jun 6.

Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, Division of Intramural Research, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0500515102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143583PMC
June 2005

Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia.

Hum Mol Genet 2004 Nov 2;13(21):2699-708. Epub 2004 Sep 2.

Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashicho, Kodaira, Tokyo 187-8502, Japan.

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http://dx.doi.org/10.1093/hmg/ddh280DOI Listing
November 2004

The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology.

J Neurosci 2004 Nov;24(45):10099-102

Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892-1379, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2680-04.2004DOI Listing
November 2004

Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia.

Proc Natl Acad Sci U S A 2004 Aug 13;101(34):12604-9. Epub 2004 Aug 13.

Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health/NIH/DHHS, Building 10, Center Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0405077101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC515104PMC
August 2004

Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain.

Arch Gen Psychiatry 2004 Jun;61(6):544-55

Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1001/archpsyc.61.6.544DOI Listing
June 2004

Candidate genes for nicotine dependence via linkage, epistasis, and bioinformatics.

Am J Med Genet B Neuropsychiatr Genet 2004 Apr;126B(1):23-36

Virginia Institute for Psychiatric & Behavioral Genetics, Virginia Commonwealth University, VA, USA.

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http://dx.doi.org/10.1002/ajmg.b.20138DOI Listing
April 2004