Richard E Frye

Richard E Frye

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Richard E Frye

Richard E Frye

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Complex heterozygous polymerase gamma mutation and cerebral folate deficiency in a child with refractory partial status.

Neurol India 2019 Jan-Feb;67(1):259-260

Neurology Section, Department of Pediatrics, University of Arkansas for Medical Sciences, Little rock, Arkansas, USA.

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http://dx.doi.org/10.4103/0028-3886.253623DOI Listing
January 2020

A comparative study of mitochondrial respiration in circulating blood cells and skeletal muscle fibers in women.

Am J Physiol Endocrinol Metab 2019 Sep 18;317(3):E503-E512. Epub 2019 Jun 18.

Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

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http://dx.doi.org/10.1152/ajpendo.00084.2019DOI Listing
September 2019

Peripheral Blood Mononuclear Cell Oxytocin and Vasopressin Receptor Expression Positively Correlates with Social and Behavioral Function in Children with Autism.

Sci Rep 2019 Sep 17;9(1):13443. Epub 2019 Sep 17.

Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1038/s41598-019-49617-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748974PMC
September 2019

Serum microRNAs in ASD: Association With Monocyte Cytokine Profiles and Mitochondrial Respiration.

Front Psychiatry 2019 10;10:614. Epub 2019 Sep 10.

Department of Pediatrics, Phoenix Children's Hospital, Phoenix, AZ, United States.

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http://dx.doi.org/10.3389/fpsyt.2019.00614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748029PMC
September 2019

Inheritance of HLA-Cw7 Associated With Autism Spectrum Disorder (ASD).

Front Psychiatry 2019 11;10:612. Epub 2019 Sep 11.

Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, United States.

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http://dx.doi.org/10.3389/fpsyt.2019.00612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749146PMC
September 2019

Clustering of co-occurring conditions in autism spectrum disorder during early childhood: A retrospective analysis of medical claims data.

Autism Res 2019 Aug 31;12(8):1272-1285. Epub 2019 May 31.

Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, New York.

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http://dx.doi.org/10.1002/aur.2128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688922PMC
August 2019

Behaviorally associated changes in neuroconnectivity following autologous umbilical cord blood infusion in young children with autism spectrum disorder.

Authors:
Richard E Frye

Ann Transl Med 2019 Jul;7(Suppl 3):S123

Division of Neurodevelopmental Disorders, Department of Neurology, Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, USA.

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http://dx.doi.org/10.21037/atm.2019.05.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685876PMC
July 2019

Mitochondrial Dysfunction Is Inducible in Lymphoblastoid Cell Lines From Children With Autism and May Involve the TORC1 Pathway.

Front Psychiatry 2019 7;10:269. Epub 2019 May 7.

Barrow Neurologic Institute at Phoenix Children's Hospital, Phoenix, AZ, United States.

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http://dx.doi.org/10.3389/fpsyt.2019.00269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514096PMC
May 2019

Reliability of the Cunningham Panel.

Transl Psychiatry 2019 04 8;9(1):129. Epub 2019 Apr 8.

Moleculera Labs, Inc, Oklahoma City, OK, USA.

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http://dx.doi.org/10.1038/s41398-019-0462-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453973PMC
April 2019

Rating of the Effectiveness of 26 Psychiatric and Seizure Medications for Autism Spectrum Disorder: Results of a National Survey.

J Child Adolesc Psychopharmacol 2019 03 6;29(2):107-123. Epub 2019 Feb 6.

2 Barrow Neurological Institute, Phoenix Children's Hospital, Phoenix, Arizona.

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http://dx.doi.org/10.1089/cap.2018.0121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442266PMC
March 2019

Variations in Mitochondrial Respiration Differ in IL-1ß/IL-10 Ratio Based Subgroups in Autism Spectrum Disorders.

Front Psychiatry 2019 20;10:71. Epub 2019 Feb 20.

Department of Child Health, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, United States.

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http://dx.doi.org/10.3389/fpsyt.2019.00071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391925PMC
February 2019

A Subset of Patients With Autism Spectrum Disorders Show a Distinctive Metabolic Profile by Dried Blood Spot Analyses.

Front Psychiatry 2018 7;9:636. Epub 2018 Dec 7.

Child Neurology and Psychiatry, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

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http://dx.doi.org/10.3389/fpsyt.2018.00636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292950PMC
December 2018

Clinical and Molecular Characteristics of Mitochondrial Dysfunction in Autism Spectrum Disorder.

Mol Diagn Ther 2018 10;22(5):571-593

Division of Neurodevelopmental Disorders, Department of Neurology, Barrow Neurological Institute, Phoenix Children's Hospital, 1919 E Thomas St, Phoenix, AZ, USA.

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http://dx.doi.org/10.1007/s40291-018-0352-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132446PMC
October 2018

Social Skills Deficits in Autism Spectrum Disorder: Potential Biological Origins and Progress in Developing Therapeutic Agents.

Authors:
Richard E Frye

CNS Drugs 2018 08;32(8):713-734

Division of Neurodevelopmental Disorders, Department of Neurology, Barrow Neurological Institute, Phoenix Children's Hospital, 1919 E Thomas St, Phoenix, AZ, 85016, USA.

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http://dx.doi.org/10.1007/s40263-018-0556-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105175PMC
August 2018

Concurrent Medical Conditions in Autism Spectrum Disorders.

Pediatr Nurs 2016 Sep-Oct;42(5):230-4

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March 2018

Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism.

Transl Psychiatry 2018 02 2;8(1):42. Epub 2018 Feb 2.

Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children's Research Institute, Little Rock, AR, USA.

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http://dx.doi.org/10.1038/s41398-017-0089-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804031PMC
February 2018

Enteric Ecosystem Disruption in Autism Spectrum Disorder: Can the Microbiota and Macrobiota be Restored?

Curr Pharm Des 2016 ;22(40):6107-6121

Slot 512-41B, Room R4041, 13 Children's Way, Little Rock, AR 72202, USA.

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http://dx.doi.org/10.2174/1381612822666160905123953DOI Listing
December 2017

Novel biomarkers of metabolic dysfunction is autism spectrum disorder: potential for biological diagnostic markers.

Metab Brain Dis 2017 12 22;32(6):1983-1997. Epub 2017 Aug 22.

Laboratory of Plant Biotechnology Applied to Crop Improvement, Faculty of Science of Sfax, University of Sfax, 3038, Sfax, Tunisia.

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http://dx.doi.org/10.1007/s11011-017-0085-2DOI Listing
December 2017

Bioenergetic variation is related to autism symptomatology.

Metab Brain Dis 2017 12 29;32(6):2021-2031. Epub 2017 Aug 29.

Autism Research Program, Arkansas Children's Research Institute, Slot 512-41B, 13 Children's Way, Little Rock, AR, 72202, USA.

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http://dx.doi.org/10.1007/s11011-017-0087-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681971PMC
December 2017

Modulation of Immunological Pathways in Autistic and Neurotypical Lymphoblastoid Cell Lines by the Enteric Microbiome Metabolite Propionic Acid.

Front Immunol 2017 22;8:1670. Epub 2017 Dec 22.

Kilee Patchell-Evans Autism Research Group, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.3389/fimmu.2017.01670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744079PMC
December 2017

High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies.

Authors:
Fadi F Hamdan Candace T Myers Patrick Cossette Philippe Lemay Dan Spiegelman Alexandre Dionne Laporte Christina Nassif Ousmane Diallo Jean Monlong Maxime Cadieux-Dion Sylvia Dobrzeniecka Caroline Meloche Kyle Retterer Megan T Cho Jill A Rosenfeld Weimin Bi Christine Massicotte Marguerite Miguet Ledia Brunga Brigid M Regan Kelly Mo Cory Tam Amy Schneider Georgie Hollingsworth David R FitzPatrick Alan Donaldson Natalie Canham Edward Blair Bronwyn Kerr Andrew E Fry Rhys H Thomas Joss Shelagh Jane A Hurst Helen Brittain Moira Blyth Robert Roger Lebel Erica H Gerkes Laura Davis-Keppen Quinn Stein Wendy K Chung Sara J Dorison Paul J Benke Emily Fassi Nicole Corsten-Janssen Erik-Jan Kamsteeg Frederic T Mau-Them Ange-Line Bruel Alain Verloes Katrin Õunap Monica H Wojcik Dara V F Albert Sunita Venkateswaran Tyson Ware Dean Jones Yu-Chi Liu Shekeeb S Mohammad Peyman Bizargity Carlos A Bacino Vincenzo Leuzzi Simone Martinelli Bruno Dallapiccola Marco Tartaglia Lubov Blumkin Klaas J Wierenga Gabriela Purcarin James J O'Byrne Sylvia Stockler Anna Lehman Boris Keren Marie-Christine Nougues Cyril Mignot Stéphane Auvin Caroline Nava Susan M Hiatt Martina Bebin Yunru Shao Fernando Scaglia Seema R Lalani Richard E Frye Imad T Jarjour Stéphanie Jacques Renee-Myriam Boucher Emilie Riou Myriam Srour Lionel Carmant Anne Lortie Philippe Major Paola Diadori François Dubeau Guy D'Anjou Guillaume Bourque Samuel F Berkovic Lynette G Sadleir Philippe M Campeau Zoha Kibar Ronald G Lafrenière Simon L Girard Saadet Mercimek-Mahmutoglu Cyrus Boelman Guy A Rouleau Ingrid E Scheffer Heather C Mefford Danielle M Andrade Elsa Rossignol Berge A Minassian Jacques L Michaud

Am J Hum Genet 2017 Nov;101(5):664-685

Centre Hospitalier Universitaire Sainte-Justine Research Center, Montreal, QC H3T1C5, Canada; Department of Neurosciences, Université de Montréal, Montreal, QC H3T1J4, Canada; Department of Pediatrics, Université de Montréal, Montreal, QC H3T1C5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673604PMC
November 2017

The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what could be the mechanisms involved?

Metab Brain Dis 2017 10 27;32(5):1335-1355. Epub 2017 Jul 27.

College of Medicine, Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital Research Institute, Little Rock, AR, 72202, USA.

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http://dx.doi.org/10.1007/s11011-017-0077-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596046PMC
October 2017

Folate metabolism abnormalities in autism: potential biomarkers.

Biomark Med 2017 Aug 3;11(8):687-699. Epub 2017 Aug 3.

Department of Medicine, State University of New York - Downstate Medical Center, Brooklyn, NY 11203, USA.

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http://dx.doi.org/10.2217/bmm-2017-0109DOI Listing
August 2017

Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study.

FASEB J 2017 03 18;31(3):904-909. Epub 2016 Nov 18.

Arkansas Children's Research Institute, Little Rock, Arkansas, USA; and.

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http://dx.doi.org/10.1096/fj.201601004RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354548PMC
March 2017

Modulation of the ultradian human nasal cycle by sleep stage and body position.

Arq Neuropsiquiatr 2017 Jan;75(1):9-14

University of Pennsylvania, Smell and Taste Center, Department of Otorhinolaryngology: Head and Neck Surgery, Philadelphia, PA, USA.

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http://dx.doi.org/10.1590/0004-282X20160178DOI Listing
January 2017

Maternal Obesity Programs Senescence Signaling and Glucose Metabolism in Osteo-Progenitors From Rat and Human.

Endocrinology 2016 Nov 21;157(11):4172-4183. Epub 2016 Sep 21.

Arkansas Children's Nutrition Center (J.-R.C., O.P.L., M.L.B., T.M.B., A.A., K.S.), Department of Pediatrics (J.-R.C., O.P.L., M.L.B., R.E.F., T.M.B., A.A., K.S.), University of Arkansas for Medical Sciences, and Arkansas Children's Hospital Research Institute (S.R., R.E.F.), Little Rock, Arkansas 72202.

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http://dx.doi.org/10.1210/en.2016-1408DOI Listing
November 2016

The Significance of the Enteric Microbiome on the Development of Childhood Disease: A Review of Prebiotic and Probiotic Therapies in Disorders of Childhood.

Clin Med Insights Pediatr 2016 9;10:91-107. Epub 2016 Oct 9.

Arkansas Children's Research Institute, Little Rock, AR, USA.; Division of Neurology, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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http://dx.doi.org/10.4137/CMPed.S38338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063840PMC
October 2016

Primary Mitochondrial Disease and Secondary Mitochondrial Dysfunction: Importance of Distinction for Diagnosis and Treatment.

Mol Syndromol 2016 Jul 3;7(3):122-37. Epub 2016 Jun 3.

Department of Pediatrics, Arkansas Children's Hospital and Arkansas Children's Research Institute, University of Arkansas for Medical Sciences, Little Rock, Ark., USA.

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http://dx.doi.org/10.1159/000446586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988248PMC
July 2016

Identification and Treatment of Pathophysiological Comorbidities of Autism Spectrum Disorder to Achieve Optimal Outcomes.

Clin Med Insights Pediatr 2016 15;10:43-56. Epub 2016 Jun 15.

Rossignol Medical Center, Irvine CA, USA.

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http://dx.doi.org/10.4137/CMPed.S38337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910649PMC
June 2016

Entorhinal Cortex Thickness across the Human Lifespan.

J Neuroimaging 2016 05 8;26(3):278-82. Epub 2015 Oct 8.

Department of Diagnostic and Psychiatry, University of Texas Health Science Center, Houston, TX.

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http://dx.doi.org/10.1111/jon.12297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826319PMC
May 2016

Neuropathological Mechanisms of Seizures in Autism Spectrum Disorder.

Front Neurosci 2016 10;10:192. Epub 2016 May 10.

School for Engineering of Matter, Transport, and Energy, Arizona State University Tempe, AZ, USA.

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http://dx.doi.org/10.3389/fnins.2016.00192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861974PMC
May 2016

Mitochondrial Dysfunction may explain symptom variation in Phelan-McDermid Syndrome.

Sci Rep 2016 Jan 29;6:19544. Epub 2016 Jan 29.

Drexel University College of Medicine, Department of Pediatrics, Neurology Section, St. Christopher's Hospital for Children, Philadelphia, PA 19134, USA.

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http://dx.doi.org/10.1038/srep19544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731780PMC
January 2016

Myoclonic epilepsy evolved into West syndrome: a patient with a novel de novo KCNQ2 mutation.

Acta Neurol Belg 2015 Sep 5;115(3):475-8. Epub 2014 Aug 5.

Neurology Section, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA,

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http://dx.doi.org/10.1007/s13760-014-0344-5DOI Listing
September 2015

Melatonin in autism spectrum disorders.

Curr Clin Pharmacol 2014 ;9(4):326-34

Rossignol Medical Center, 3800 West Eau Gallie Blvd., Melbourne, FL 32934, USA.

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http://dx.doi.org/10.2174/15748847113086660072DOI Listing
July 2015

Metabolic and mitochondrial disorders associated with epilepsy in children with autism spectrum disorder.

Authors:
Richard E Frye

Epilepsy Behav 2015 Jun 4;47:147-57. Epub 2014 Nov 4.

Autism Research Program, Arkansas Children's Hospital Research Institute, Little Rock, AR, USA; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yebeh.2014.08.134DOI Listing
June 2015

Gastrointestinal dysfunction in autism spectrum disorder: the role of the mitochondria and the enteric microbiome.

Microb Ecol Health Dis 2015 7;26:27458. Epub 2015 May 7.

Kilee Patchell-Evans Autism Research Group, Division of Developmental Disabilities, Departments of Psychology and Psychiatry, University of Western Ontario, London, ON, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425813PMC
http://dx.doi.org/10.3402/mehd.v26.27458DOI Listing
May 2015

Introduction.

Microb Ecol Health Dis 2015 7;26:28168. Epub 2015 May 7.

Autism Research Program, Arkansas Children's Hospital Research Institute, Little Rock, AR, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425811PMC
http://dx.doi.org/10.3402/mehd.v26.28168DOI Listing
May 2015

RASopathies: a window into the molecular mechanisms underlying neurodevelopmental disorders.

Authors:
Richard E Frye

Dev Med Child Neurol 2015 Apr 18;57(4):315-6. Epub 2014 Nov 18.

Department of Pediatrics, Arkansas Children's Hospital and Arkansas Children's Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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http://dx.doi.org/10.1111/dmcn.12626DOI Listing
April 2015

Increased susceptibility to ethylmercury-induced mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines.

J Toxicol 2015 21;2015:573701. Epub 2015 Jan 21.

Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital Research Institute, 13 Children's Way, Slot 512-41B, Little Rock, AR 72202, USA.

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http://dx.doi.org/10.1155/2015/573701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320799PMC
February 2015

Metabolic pathology of autism in relation to redox metabolism.

Biomark Med 2014 ;8(3):321-30

Arkansas Children's Hospital Research Institute, Department of Pediatrics, University of Arkansas for Medical Sciences, Slot 512-41B, 13 Children's Way, Little Rock, AR 72202, USA.

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http://dx.doi.org/10.2217/bmm.13.158DOI Listing
November 2014

The use of medications approved for Alzheimer's disease in autism spectrum disorder: a systematic review.

Front Pediatr 2014 22;2:87. Epub 2014 Aug 22.

Arkansas Children's Hospital Research Institute, University of Arkansas for Medical Sciences , Little Rock, AR , USA.

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http://dx.doi.org/10.3389/fped.2014.00087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141213PMC
September 2014

Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism.

Front Physiol 2014 22;5:150. Epub 2014 Apr 22.

Department of Pediatrics, Arkansas Children's Hospital Research Institute, University of Arkansas for Medical Sciences Little Rock, AR, USA.

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http://dx.doi.org/10.3389/fphys.2014.00150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001006PMC
June 2014

Clinical potential, safety, and tolerability of arbaclofen in the treatment of autism spectrum disorder.

Authors:
Richard E Frye

Drug Healthc Patient Saf 2014 10;6:69-76. Epub 2014 May 10.

Arkansas Children's Hospital Research Institute, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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http://dx.doi.org/10.2147/DHPS.S39595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025936PMC
June 2014

Network-based analysis reveals stronger local diffusion-based connectivity and different correlations with oral language skills in brains of children with high functioning autism spectrum disorders.

Hum Brain Mapp 2014 Feb 24;35(2):396-413. Epub 2012 Sep 24.

Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas.

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http://dx.doi.org/10.1002/hbm.22185DOI Listing
February 2014

Effectiveness of methylcobalamin and folinic Acid treatment on adaptive behavior in children with autistic disorder is related to glutathione redox status.

Autism Res Treat 2013 12;2013:609705. Epub 2013 Oct 12.

Department of Pediatrics, Arkansas Children's Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA.

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http://dx.doi.org/10.1155/2013/609705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810468PMC
November 2013

A lack of statistical pitfalls in the comparison of multivariate causality measures for effective causality.

Authors:
Richard E Frye

Comput Biol Med 2013 Aug 26;43(7):962-5. Epub 2013 Feb 26.

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http://dx.doi.org/10.1016/j.compbiomed.2013.02.001DOI Listing
August 2013

Global cerebral and regional multimodal neuroimaging markers of the neurobiology of autism: development and cognition.

J Child Neurol 2013 Jul 16;28(7):874-85. Epub 2012 Aug 16.

Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1177/0883073812452917DOI Listing
July 2013

Tract-based spatial statistics reveal altered relationship between non-verbal reasoning abilities and white matter integrity in autism spectrum disorder.

J Int Neuropsychol Soc 2013 Jul 8;19(6):723-8. Epub 2013 Apr 8.

Department of Psychology and Program in Behavioral and Cognitive Neuroscience, The City College and Graduate Center of the City University of New York, New York, NY, USA.

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http://www.journals.cambridge.org/abstract_S1355617713000325
Publisher Site
http://dx.doi.org/10.1017/S1355617713000325DOI Listing
July 2013

Sex differences in the use of delayed semantic context when listening to disrupted speech.

Arch Sex Behav 2013 Feb 21;42(2):197-201. Epub 2012 Mar 21.

Brain, Behavior and Cognition Program, Department of Psychology, Boston University, 64 Cummington St., Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s10508-012-9941-7DOI Listing
February 2013

Synchronization between the anterior and posterior cortex determines consciousness level in patients with traumatic brain injury (TBI).

Brain Res 2012 Oct 29;1476:22-30. Epub 2012 Mar 29.

Human Neuropsychology Laboratory, University of Seville, Spain; Center for Brain Injury Rehabilitation (C.RE.CER.), Seville, Spain.

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http://dx.doi.org/10.1016/j.brainres.2012.03.055DOI Listing
October 2012

Mitochondrial disease in 22q13 duplication syndrome.

Authors:
Richard E Frye

J Child Neurol 2012 Jul 28;27(7):942-9. Epub 2012 Feb 28.

Department of Pediatrics, Division of Child Neurology, Arkansas Children's Hospital, Little Rock, AR 72202, USA.

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http://dx.doi.org/10.1177/0883073811429858DOI Listing
July 2012

Advances and limitations in our knowledge of cortical reorganization in cerebral palsy.

Authors:
Richard E Frye

Dev Med Child Neurol 2012 Apr 23;54(4):298-9. Epub 2011 Nov 23.

Department of Pediatrics, Arkansas Children's Hospital, Little Rock, AR, USA.

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http://dx.doi.org/10.1111/j.1469-8749.2011.04157.xDOI Listing
April 2012

Multichannel least-squares linear regression provides a fast, accurate, unbiased and robust estimation of Granger causality for neurophysiological data.

Comput Biol Med 2011 Dec;41(12):1118-31

Arkansas Children's Hospital Research Institute, University of Arkansas Medical Sciences, Little Rock, AR 72202, USA.

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http://dx.doi.org/10.1016/j.compbiomed.2011.04.012DOI Listing
December 2011

A comparison of multivariate causality based measures of effective connectivity.

Comput Biol Med 2011 Dec 13;41(12):1132-41. Epub 2011 Jul 13.

Departments of Computer Science, South Texas College, McAllen, TX 78501, USA.

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http://dx.doi.org/10.1016/j.compbiomed.2011.06.007DOI Listing
December 2011

Mitochondrial dysfunction and myoclonic epilepsy: cause or effect or both?

Authors:
Richard E Frye

J Child Neurol 2011 Oct;26(10):1332-4

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http://dx.doi.org/10.1177/0883073811420720DOI Listing
October 2011

Melatonin in autism spectrum disorders: a systematic review and meta-analysis.

Dev Med Child Neurol 2011 Sep 19;53(9):783-792. Epub 2011 Apr 19.

 International Child Development Resource Center, Melbourne, FL, USA Division of Child and Adolescent Neurology and Children's Learning Institute, Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, TX, USA.

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http://dx.doi.org/10.1111/j.1469-8749.2011.03980.xDOI Listing
September 2011

Diffusion tensor quantification of the relations between microstructural and macrostructural indices of white matter and reading.

Hum Brain Mapp 2011 Aug 27;32(8):1220-35. Epub 2010 Jul 27.

Division of Child and Adolescent Neurology, Department of Pediatrics, University of Texas Health Science Center, 7000 Fannin, Houston, TX 77030, USA.

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http://doi.wiley.com/10.1002/hbm.21103
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http://dx.doi.org/10.1002/hbm.21103DOI Listing
August 2011

Central tetrahydrobiopterin concentration in neurodevelopmental disorders.

Authors:
Richard E Frye

Front Neurosci 2010 8;4:52. Epub 2010 Jul 8.

Department of Pediatrics, Division of Child and Adolescent Neurology and The Children's Learning Institute, University of Texas Health Science Center Houston, TX, USA.

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http://dx.doi.org/10.3389/fnins.2010.00052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906199PMC
July 2011

Greater Pre-Stimulus Effective Connectivity from the Left Inferior Frontal Area to other Areas is Associated with Better Phonological Decoding in Dyslexic Readers.

Front Syst Neurosci 2010 2;4:156. Epub 2010 Dec 2.

Department of Pediatrics, Division of Child and Adolescent Neurology and the Children's Learning Institute, University of Texas Health Science Center Houston, TX, USA.

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http://dx.doi.org/10.3389/fnsys.2010.00156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001755PMC
July 2011

Leber's hereditary optic neuropathy mutations associated with infantile-onset myoclonic epilepsy.

Authors:
Richard E Frye

J Child Neurol 2011 Jun 27;26(6):782-5. Epub 2011 Apr 27.

Division of Child and Adolescent Neurology, Department of Pediatrics, and Children's Learning Institute, University of Texas Health Science Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1177/0883073810391531DOI Listing
June 2011

Mitochondrial dysfunction can connect the diverse medical symptoms associated with autism spectrum disorders.

Pediatr Res 2011 May;69(5 Pt 2):41R-7R

Department of Pediatrics, The Children's Learning Institute, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1203/PDR.0b013e318212f16bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179978PMC
May 2011

Traditional and non-traditional treatments for autism spectrum disorder with seizures: an on-line survey.

BMC Pediatr 2011 May 18;11:37. Epub 2011 May 18.

Department of Pediatrics, University of Texas Health Science Center, Houston, USA.

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http://dx.doi.org/10.1186/1471-2431-11-37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123184PMC
May 2011

Diffusion tensor-based regional gray matter tissue segmentation using the international consortium for brain mapping atlases.

Hum Brain Mapp 2011 Jan;32(1):107-17

Department of Diagnostic and Interventional Imaging, University of Texas Medical School at Houston, Houston, Texas, USA.

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http://dx.doi.org/10.1002/hbm.21004DOI Listing
January 2011

Surface area accounts for the relation of gray matter volume to reading-related skills and history of dyslexia.

Cereb Cortex 2010 Nov 12;20(11):2625-35. Epub 2010 Feb 12.

Division of Child and Adolescent Neurology, Department of Pediatrics, University of Texas Health Science Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/cercor/bhq010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981021PMC
November 2010

Human brain atlas-based volumetry and relaxometry: application to healthy development and natural aging.

Magn Reson Med 2010 Nov 25;64(5):1382-9. Epub 2010 Aug 25.

Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/mrm.22515DOI Listing
November 2010

Diffusion tensor tractography of the human brain cortico-ponto-cerebellar pathways: a quantitative preliminary study.

J Magn Reson Imaging 2010 Oct;32(4):809-17

Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/jmri.22330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492525PMC
October 2010

Preterm birth and maternal responsiveness during childhood are associated with brain morphology in adolescence.

J Int Neuropsychol Soc 2010 Sep 8;16(5):784-94. Epub 2010 Jul 8.

Department of Pediatrics, University of Texas Health Science Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1017/S1355617710000585DOI Listing
September 2010

Superior longitudinal fasciculus and cognitive dysfunction in adolescents born preterm and at term.

Dev Med Child Neurol 2010 Aug 24;52(8):760-6. Epub 2010 Feb 24.

Department of Pediatrics, University of Texas Health Science Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1111/j.1469-8749.2010.03633.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910222PMC
August 2010

Tetrahydrobiopterin as a novel therapeutic intervention for autism.

Neurotherapeutics 2010 Jul;7(3):241-9

Division of Child and Adolescent Neurology and The Children's Learning Institute, Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1016/j.nurt.2010.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908599PMC
July 2010

Information communication networks in severe traumatic brain injury.

Brain Topogr 2010 Jun 12;23(2):221-6. Epub 2010 Mar 12.

Biomedical Imaging Lab, Department of Engineering Technology, University of Houston, 218 Philip G. Hoffman Hall, Houston, TX, 77204-3058, USA.

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http://dx.doi.org/10.1007/s10548-010-0139-9DOI Listing
June 2010

Increased left prefrontal activation during an auditory language task in adolescents born preterm at high risk.

Brain Res 2010 Jun 8;1336:89-97. Epub 2010 Apr 8.

Division of Child and Adolescent Neurology, Department of Pediatrics, University of Texas Health Science Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.brainres.2010.03.093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881563PMC
June 2010

Electroencephalogram discharges in atypical cognitive development.

J Child Neurol 2010 May 18;25(5):556-66. Epub 2010 Mar 18.

Department of Pediatrics, Division of Child and Adolescent Neurology, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.

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http://journals.sagepub.com/doi/10.1177/0883073809344743
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http://dx.doi.org/10.1177/0883073809344743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896832PMC
May 2010

Increased prefrontal activation in adolescents born prematurely at high risk during a reading task.

Brain Res 2009 Dec 29;1303:111-9. Epub 2009 Sep 29.

Division of Child and Adolescent Neurology, University of Texas Health Science Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.brainres.2009.09.091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783693PMC
December 2009

15q11.2-13 duplication, mitochondrial dysfunction, and developmental disorders.

Authors:
Richard E Frye

J Child Neurol 2009 Oct 17;24(10):1316-20. Epub 2009 Jun 17.

Department of Pediatrics and Neurology, Division of Child and Adolescent Neurology, University of Texas Health Science Center, Houston, Texas, USA.

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http://dx.doi.org/10.1177/0883073809333531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919279PMC
October 2009

Executive dysfunction in poor readers born prematurely at high risk.

Dev Neuropsychol 2009 ;34(3):254-71

Division of Child and Adolescent Neurology and The Children's Learning Institute, Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1080/87565640902805727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692028PMC
August 2009

Reversible posterior leukoencephalopathy syndrome in sickle-cell anemia.

Authors:
Richard E Frye

Pediatr Neurol 2009 Apr;40(4):298-301

Department of Pediatrics, University of Texas Health Science Center, Houston, Texas, USA.

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http://dx.doi.org/10.1016/j.pediatrneurol.2008.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903963PMC
April 2009

Functional Neuroimaging of Language Using Magnetoencephalography.

Phys Life Rev 2009 Mar;6(1):1-10

Department of Pediatrics, Division of Child and Adolescent Neurology, University of Texas Health Science Center, Houston, TX.

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https://linkinghub.elsevier.com/retrieve/pii/S15710645080002
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http://dx.doi.org/10.1016/j.plrev.2008.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754842PMC
March 2009

Receptive language organization in high-functioning autism.

J Child Neurol 2009 Feb;24(2):231-6

Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1177/0883073808329572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896833PMC
February 2009