Publications by authors named "Richard E Clark"

94Publications

The chronic myeloid leukaemia story in the United Kingdom since 1960.

Authors:
Richard E Clark

Br J Haematol 2020 Nov;191(4):521-526

Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/bjh.17149DOI Listing
November 2020

Another set of guidelines for chronic myeloid leukaemia.

Authors:
Richard E Clark

Br J Haematol 2020 Jul 26. Epub 2020 Jul 26.

Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/bjh.16970DOI Listing
July 2020

Serotonin re-uptake transporter gene polymorphisms are associated with imatinib-induced diarrhoea in chronic myeloid leukaemia patients.

Sci Rep 2020 05 21;10(1):8394. Epub 2020 May 21.

The Wolfson Centre for Personalised Medicine, The MRC Centre for Drug Safety Science, Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1038/s41598-020-65350-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242433PMC
May 2020

Molecular monitoring during dose reduction predicts recurrence after TKI cessation in CML.

Blood 2020 03;135(10):766-769

Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1182/blood.2019003395DOI Listing
March 2020

Tyrosine Kinase Inhibitor Therapy Discontinuation for Patients with Chronic Myeloid Leukaemia in Clinical Practice.

Authors:
Richard E Clark

Curr Hematol Malig Rep 2019 12;14(6):507-514

Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Room 150, First floor, Sherrington Building, Ashton Street, Liverpool,, L69 3GE, UK.

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http://dx.doi.org/10.1007/s11899-019-00548-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934633PMC
December 2019

Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5' AMP-activated protein kinase signalling in malignant cells.

Biochem J 2019 08 15;476(15):2255-2269. Epub 2019 Aug 15.

Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, U.K.

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http://dx.doi.org/10.1042/BCJ20190121DOI Listing
August 2019

Heterogeneous leukemia stem cells in myeloid blast phase chronic myeloid leukemia.

Blood Adv 2016 Dec 14;1(3):160-169. Epub 2016 Dec 14.

Medical Research Council Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1182/bloodadvances.2016000810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737170PMC
December 2016

Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia.

Clin Cancer Res 2017 May 17;23(9):2289-2300. Epub 2016 Nov 17.

Department of Hematology and Oncology with Sections BMT and Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1930DOI Listing
May 2017

Evaluating the use of plerixafor in stem cell mobilisation - an economic analysis of the PHANTASTIC trial.

J Clin Apher 2016 Oct 29;31(5):434-42. Epub 2015 Sep 29.

Haematology Department, Royal Liverpool University Hospital, Liverpool, United Kingdom.

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http://dx.doi.org/10.1002/jca.21433DOI Listing
October 2016

c-Myc inhibition decreases CIP2A and reduces BCR-ABL1 tyrosine kinase activity in chronic myeloid leukemia.

Haematologica 2015 May 6;100(5):e179-82. Epub 2015 Feb 6.

Department of Haematology, Royal Liverpool and Broadgreen University Hospital, Liverpool, UK

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http://dx.doi.org/10.3324/haematol.2014.115691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420226PMC
May 2015

PTCH1 expression at diagnosis predicts imatinib failure in chronic myeloid leukaemia patients in chronic phase.

Am J Hematol 2015 Jan 18;90(1):20-6. Epub 2014 Oct 18.

Centre for Haematology, Department of Medicine, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ajh.23857DOI Listing
January 2015

Low leukotriene B4 receptor 1 leads to ALOX5 downregulation at diagnosis of chronic myeloid leukemia.

Haematologica 2014 Nov 5;99(11):1710-5. Epub 2014 Sep 5.

Department of Molecular and Clinical Cancer Medicine (Haematology), University of Liverpool, UK.

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http://dx.doi.org/10.3324/haematol.2013.101972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222473PMC
November 2014

Evidence that the pregnane X and retinoid receptors PXR, RAR and RXR may regulate transcription of the transporter hOCT1 in chronic myeloid leukaemia cells.

Eur J Haematol 2015 Jan 31;94(1):74-8. Epub 2014 Jul 31.

Section of Haematology, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/ejh.12409DOI Listing
January 2015

Live cell interactome of the human voltage dependent anion channel 3 (VDAC3) revealed in HeLa cells by affinity purification tag technique.

Mol Biosyst 2014 Aug;10(8):2134-45

Department of Biological, Geological and Environmental Sciences, Section of Biochemistry and Molecular Biology, University of Catania, Italy.

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http://dx.doi.org/10.1039/c4mb00237gDOI Listing
August 2014

The use of cognitive task analysis to reveal the instructional limitations of experts in the teaching of procedural skills.

Acad Med 2014 May;89(5):811-6

Dr. Sullivan is associate professor and associate chair for education, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California. Dr. Yates is associate professor, Rossier School of Education, University of Southern California, Los Angeles, California. Dr. Inaba is associate professor, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California. Dr. Lam is assistant professor, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California. Dr. Clark is professor emeritus, Rossier School of Education, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1097/ACM.0000000000000224DOI Listing
May 2014

The STS National Database.

Ann Thorac Surg 2014 Jan;97(1 Suppl):S48-54

Professor Emeritus, University of Florida, Jacksonville, Florida.

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http://dx.doi.org/10.1016/j.athoracsur.2013.10.015DOI Listing
January 2014

Cognitive task analysis-based design and authoring software for simulation training.

Mil Med 2013 Oct;178(10 Suppl):7-14

Center for Cognitive Technology, Rossier School of Education, University of Southern California, 250 N. Harbor Drive, Suite 309, Redondo Beach, CA 90277.

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http://dx.doi.org/10.7205/MILMED-D-13-00265DOI Listing
October 2013

Peroxisome proliferator-activated receptor activation increases imatinib uptake and killing of chronic myeloid leukemia cells.

Exp Hematol 2012 Oct 5;40(10):811-9.e2. Epub 2012 Jun 5.

Section of Haematology, Department of Molecular and Cancer Medicine, the University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1016/j.exphem.2012.05.013DOI Listing
October 2012

Predictive value of early molecular response in patients with chronic myeloid leukemia treated with first-line dasatinib.

Blood 2012 Jul 29;120(2):291-4. Epub 2012 May 29.

Department of Haematology, Imperial College London, Hammersmith Hospital, Du Cane Road, London, United Kingdom.

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http://dx.doi.org/10.1182/blood-2012-01-407486DOI Listing
July 2012

Online evaluation programs: benefits and limitations.

J Cancer Educ 2012 Apr;27(1 Suppl):S24-31

Native American Cancer Research Corporation (NACR), 3022 South Nova Road, Pine, CO 80470-7830, USA.

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http://dx.doi.org/10.1007/s13187-012-0320-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544411PMC
April 2012

The use of cognitive task analysis to improve instructional descriptions of procedures.

J Surg Res 2012 Mar 2;173(1):e37-42. Epub 2011 Oct 2.

Center for Cognitive Technology, Rossier School of Education, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.

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http://dx.doi.org/10.1016/j.jss.2011.09.003DOI Listing
March 2012

Nilotinib is superior to imatinib as first-line therapy of chronic myeloid leukemia: the ENESTnd study.

Expert Rev Hematol 2010 Dec 9;3(6):665-73. Epub 2010 Nov 9.

HRB Clinical Research Facility, National University of Ireland, Galway & Trinity College, Dublin, Ireland.

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http://dx.doi.org/10.1586/ehm.10.61DOI Listing
December 2010

A prospective evaluation of cardiac function in patients with chronic myeloid leukaemia treated with imatinib.

Leuk Res 2011 Jan 27;35(1):49-51. Epub 2010 Oct 27.

Department of Haematology, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1016/j.leukres.2010.08.020DOI Listing
January 2011

BCR-ABL peptide vaccination in healthy subjects: immunological responses are equivalent to those in chronic myeloid leukaemia patients.

Leuk Res 2011 Mar 22;35(3):369-72. Epub 2010 Jun 22.

Department of Haematology, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1016/j.leukres.2010.05.028DOI Listing
March 2011

A genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers.

Mol Cancer 2010 Feb 25;9:44. Epub 2010 Feb 25.

Department of Medical and Molecular Genetics, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B152TT, UK.

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http://molecular-cancer.biomedcentral.com/articles/10.1186/1
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http://dx.doi.org/10.1186/1476-4598-9-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838813PMC
February 2010

Intra-operative decision making: more than meets the eye.

J Biomed Inform 2011 Jun 20;44(3):486-96. Epub 2010 Jan 20.

Northwestern University, Department of Surgery, Chicago, IL, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15320464100000
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http://dx.doi.org/10.1016/j.jbi.2010.01.001DOI Listing
June 2011

Facts and uncertainties in monitoring treatment response in chronic myeloid leukaemia.

Authors:
Richard E Clark

Leuk Res 2009 Sep 15;33(9):1151-5. Epub 2009 May 15.

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http://dx.doi.org/10.1016/j.leukres.2009.04.001DOI Listing
September 2009

Soluble HLA/peptide monomers cross-linked with co-stimulatory antibodies onto a streptavidin core molecule efficiently stimulate antigen-specific T cell responses.

Cancer Immunol Immunother 2009 Sep 5;58(9):1459-70. Epub 2009 May 5.

Anthony Nolan Research Institute, The Royal Free Hospital, University College of London, Hampstead, London NW3 2QG, UK.

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http://dx.doi.org/10.1007/s00262-009-0711-xDOI Listing
September 2009

Tumour antigen-targeted immunotherapy for chronic myeloid leukaemia: is it still viable?

Cancer Immunol Immunother 2009 Sep 4;58(9):1489-99. Epub 2009 Mar 4.

The John Van Geest Cancer Research Centre, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK.

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http://dx.doi.org/10.1007/s00262-009-0675-xDOI Listing
September 2009

Pharmacologic markers and predictors of responses to imatinib therapy in patients with chronic myeloid leukemia.

Leuk Lymphoma 2008 Apr;49(4):639-42

University Department of Haematology, Royal Liverpool University Hospital, Liverpool, UK.

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http://dx.doi.org/10.1080/10428190701858823DOI Listing
April 2008

Immunotherapeutic strategies in chronic myeloid leukemia.

Authors:
Richard E Clark

Curr Hematol Malig Rep 2007 May;2(2):89-94

Department of Haematology, Royal Liverpool University Hospital, Prescot St., Liverpool L7 8XP, UK.

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http://link.springer.com/10.1007/s11899-007-0013-3
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http://dx.doi.org/10.1007/s11899-007-0013-3DOI Listing
May 2007

Evidence that a BCR-ABL fusion peptide does not induce lymphocyte proliferation or cytokine production in vitro.

Leuk Res 2007 Dec 26;31(12):1675-81. Epub 2007 Feb 26.

Division of Immunology, University of Liverpool, UK.

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http://dx.doi.org/10.1016/j.leukres.2007.01.007DOI Listing
December 2007

The role of serial BCR-ABL transcript monitoring in predicting the emergence of BCR-ABL kinase mutations in imatinib-treated patients with chronic myeloid leukemia.

Haematologica 2006 Feb;91(2):235-9

Department of Haematology, Royal Liverpool University Hospital, Prescot St, Liverpool L7 8XP, United Kingdom.

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February 2006

Circulating bcr-abl-specific CD8+ T cells in chronic myeloid leukemia patients and healthy subjects.

Haematologica 2005 Oct;90(10):1315-23

Department of Hematology, University of Liverpool, Prescot St., Liverpool L7 8XP, United Kingdom.

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October 2005

Active transport of imatinib into and out of cells: implications for drug resistance.

Blood 2004 Dec 17;104(12):3739-45. Epub 2004 Aug 17.

Department of Pharmacology and Therapeutics, The University of Liverpool, Ashton Street, Liverpool, L69 3GE, United Kingdom.

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http://dx.doi.org/10.1182/blood-2003-12-4276DOI Listing
December 2004

Cognitive task analysis for teaching technical skills in an inanimate surgical skills laboratory.

Am J Surg 2004 Jan;187(1):114-9

Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://www.cogtech.usc.edu/publications/velmahos_clark.pdf
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http://dx.doi.org/10.1016/j.amjsurg.2002.12.005DOI Listing
January 2004

CD34 positive selection as prophylaxis against graft versus host disease in allogeneic peripheral blood stem cell transplantation.

Leuk Lymphoma 2003 Sep;44(9):1509-13

Jose Carreras Bone Marrow Transplant Unit, Royal Liverpool University Hospital, Prescot Street, Liverpool, L7 8XP, UK.

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http://www.tandfonline.com/doi/full/10.1080/1042819031000083
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http://dx.doi.org/10.1080/1042819031000083019DOI Listing
September 2003

CpG oligodeoxynucleotide 5mer-induced apoptosis in MOLT-4 leukaemia cells does not require caspase 3 or new protein synthesis.

Nucleic Acids Res 2003 May;31(9):2297-304

School of Biological Sciences, The University of Liverpool, Liverpool, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC154220PMC
http://dx.doi.org/10.1093/nar/gkg334DOI Listing
May 2003

The early molecular response to imatinib predicts cytogenetic and clinical outcome in chronic myeloid leukaemia.

Br J Haematol 2003 Mar;120(6):990-9

Department of Haematology, Royal Liverpool University Hospital, UK.

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http://dx.doi.org/10.1046/j.1365-2141.2003.04200.xDOI Listing
March 2003

Bone turnover following autologous transplantation in multiple myeloma.

Leuk Lymphoma 2002 Mar;43(3):511-6

Department of Haematology, University of Liverpool, UK.

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http://dx.doi.org/10.1080/10428190290011985DOI Listing
March 2002

LEAFLET PROSTHETIC VALVES.

Cardiovasc Dis 1974 ;1(5):433-448

Division of Cardiothoracic Surgery and the Departments of Civil & Environmental Engineering and Mechanical and Aerospace Engineering, Washington University, St. Louis, Missouri 63110.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC287514PMC
January 1974