Richard B Horenstein

Richard B Horenstein

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Richard B Horenstein

Richard B Horenstein

Publications by authors named "Richard B Horenstein"

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Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.

JACC Cardiovasc Interv 2018 01 1;11(2):181-191. Epub 2017 Nov 1.

Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida; Department of Medicine, Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida.

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http://dx.doi.org/10.1016/j.jcin.2017.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775044PMC
January 2018

Pharmacogenetic Associations of β1-Adrenergic Receptor Polymorphisms With Cardiovascular Outcomes in the SPS3 Trial (Secondary Prevention of Small Subcortical Strokes).

Stroke 2017 05 28;48(5):1337-1343. Epub 2017 Mar 28.

From the Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville (O.M., C.W.M., Y.G., J.A.J.); Department of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, PA (L.A.M.); College of Pharmacy, University of Texas, Austin (R.L.T.); Division of Endocrinology, Diabetes and Nutrition and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore (R.B.H., A.R.S., B.D.M.); Department of Neurology, University of British Columbia, Vancouver, Canada (O.R.B.); and Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, MD (B.D.M.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404951PMC
May 2017

Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.

Pharmacogenet Genomics 2017 04;27(4):159-163

aSchool of Medicine, Division of Endocrinology, Diabetes and Nutrition, and Program for Personalized and Genomic Medicine, University of Maryland, Baltimore bGeriatric Research and Education Clinical Center, Veterans Administration Medical Center, Baltimore cClinical Pharmacology Program, National Cancer Institute, Bethesda dApplied and Developmental Research, SAIC-Frederick Inc., National Cancer Institute, Frederick, Maryland, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346037PMC
April 2017

A systematic analysis and comparison of warfarin initiation strategies.

Pharmacogenet Genomics 2016 Oct;26(10):445-52

Departments of aBiostatistics and Epidemiology bMedicine, University of Pennsylvania, Philadelphia, Pennsylvania cDepartment of Medicine, Washington University in St Louis, St Louis, Missouri dDepartment of Medicine, University of Maryland, Baltimore, Maryland eDepartment of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014593PMC
October 2016

Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study.

J Am Heart Assoc 2015 Oct 26;4(10):e002203. Epub 2015 Oct 26.

Duke University Medical Center, Durham, NC (A.G., R.K.D.) Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC (R.K.D.) Duke Institute for Brain Sciences, Duke University, Durham, NC (R.K.D.) Institute of Genome Science and Policy, Durham, NC (R.K.D.).

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http://dx.doi.org/10.1161/JAHA.115.002203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845113PMC
October 2015

CYP2C19 metabolizer status and clopidogrel efficacy in the Secondary Prevention of Small Subcortical Strokes (SPS3) study.

J Am Heart Assoc 2015 May 27;4(6):e001652. Epub 2015 May 27.

Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD (B.D.M., R.B.H., J.P.L., A.R.S.) Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD (B.D.M., R.B.H., J.P.L., A.R.S.) Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, Baltimore, MD (B.D.M., A.R.S.).

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http://dx.doi.org/10.1161/JAHA.114.001652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599525PMC
May 2015

Effectiveness of clopidogrel dose escalation to normalize active metabolite exposure and antiplatelet effects in CYP2C19 poor metabolizers.

J Clin Pharmacol 2014 Aug 7;54(8):865-73. Epub 2014 Apr 7.

Program in Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/jcph.293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113831PMC
August 2014

Null mutation in hormone-sensitive lipase gene and risk of type 2 diabetes.

N Engl J Med 2014 Jun 21;370(24):2307-2315. Epub 2014 May 21.

Program for Personalized and Genomic Medicine and Department of Medicine, University of Maryland School of Medicine (J.S.A., L.M.Y.-A., R.B.H., T.I.P., U.T.S., S.C., S.S., J.R.O., D.-W.G., J.C.M., A.R.S., C.S., C.M.D.), and the Geriatrics Research and Education Clinical Center (D.-W.G., A.S.R., A.R.S., C.S.), Department of Radiology and Nuclear Medicine (R.J.B.), and the Veterans Affairs (VA) Research Service, Department of Medicine, Division of Gerontology and Geriatric Medicine (A.S.R.), Baltimore VA Medical Center - all in Baltimore; and the Department of Medicine, Columbia University, New York (W.S.B.).

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http://dx.doi.org/10.1056/NEJMoa1315496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096982PMC
June 2014

Pharmacogenomics of anti-platelet and anti-coagulation therapy.

Curr Cardiol Rep 2013 Jul;15(7):381

Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, and the Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1007/s11886-013-0381-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809070PMC
July 2013

The ABCG8 G574R variant, serum plant sterol levels, and cardiovascular disease risk in the Old Order Amish.

Arterioscler Thromb Vasc Biol 2013 Feb 13;33(2):413-9. Epub 2012 Dec 13.

Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.112.245480
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http://dx.doi.org/10.1161/ATVBAHA.112.245480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817740PMC
February 2013

A sensitive and rapid ultra HPLC-MS/MS method for the simultaneous detection of clopidogrel and its derivatized active thiol metabolite in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2012 Jan 26;880(1):132-9. Epub 2011 Nov 26.

Clinical Pharmacology Program, Office of the Clinical Director, National Cancer Institute, Bethesda, MD 20892, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S157002321100760
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http://dx.doi.org/10.1016/j.jchromb.2011.11.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246081PMC
January 2012

Does bariatric surgery reduce obesity-related comorbidities?

Curr Diab Rep 2005 Apr;5(2):133-5

Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, 660 W. Redwood Street, Room 494, Baltimore, MD 21201, USA.

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April 2005

Genetics of diabetes.

Rev Endocr Metab Disord 2004 Mar;5(1):25-36

University of Maryland School of Medicine, Division of Endocrinology, Diabetes and Nutrition, 660 West Redwood Street, Room 494, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1023/B:REMD.0000016122.84105.75DOI Listing
March 2004

Adrenal cortical adenoma with excess black pigment deposition, combined with myelolipoma and clinical Cushing's syndrome.

Int J Surg Pathol 2004 Jan;12(1):57-61

Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1177/106689690401200111DOI Listing
January 2004

Cholesterol predicts stroke mortality in the Women's Pooling Project.

Stroke 2002 Jul;33(7):1863-8

Department of Medicine, University of Maryland Medical System, Baltimore, USA.

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http://dx.doi.org/10.1161/01.str.0000020093.67593.0bDOI Listing
July 2002