Richard A Rachubinski

Richard A Rachubinski

UNVERIFIED PROFILE

Are you Richard A Rachubinski?   Register this Author

Register author
Richard A Rachubinski

Richard A Rachubinski

Publications by authors named "Richard A Rachubinski"

Are you Richard A Rachubinski?   Register this Author

72Publications

-Reads

Reconstitution of human peroxisomal β-oxidation in yeast.

FEMS Yeast Res 2018 Dec;18(8)

Department of Cell Biology, University of Alberta, Edmonton, MSB 5-14, Edmonton, Alberta T6G 2H7, Canada.

View Article
December 2018

Dysfunctional peroxisomes compromise gut structure and host defense by increased cell death and Tor-dependent autophagy.

Mol Biol Cell 2018 Sep 6:mbcE18070434. Epub 2018 Sep 6.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
September 2018

Involvement of SNARE protein Ykt6 in glycosome biogenesis in Trypanosoma brucei.

Mol Biochem Parasitol 2017 12 28;218:28-37. Epub 2017 Oct 28.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada. Electronic address:

View Article
December 2017

Peroxisome-Mediated Metabolism Is Required for Immune Response to Microbial Infection.

Immunity 2017 07;47(1):93-106.e7

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada. Electronic address:

View Article
July 2017

Motors, anchors, and connectors: orchestrators of organelle inheritance.

Annu Rev Cell Dev Biol 2015 5;31:55-81. Epub 2015 Oct 5.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada; email:

View Article
September 2016

How peroxisomes partition between cells. A story of yeast, mammals and filamentous fungi.

Curr Opin Cell Biol 2016 08 26;41:73-80. Epub 2016 Apr 26.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada. Electronic address:

View Article
August 2016

Peroxins Pex30 and Pex29 Dynamically Associate with Reticulons to Regulate Peroxisome Biogenesis from the Endoplasmic Reticulum.

J Biol Chem 2016 07 29;291(30):15408-27. Epub 2016 Apr 29.

From the Center for Infectious Disease Research and Institute for Systems Biology, Seattle, Washington 98109 and

View Article
July 2016

Sharing with your children: Mechanisms of peroxisome inheritance.

Biochim Biophys Acta 2016 May 24;1863(5):1014-8. Epub 2015 Nov 24.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada. Electronic address:

View Article
May 2016

A Systematic Cell-Based Analysis of Localization of Predicted Drosophila Peroxisomal Proteins.

Traffic 2016 May 1;17(5):536-53. Epub 2016 Mar 1.

Department of Cell Biology, University of Alberta, Medical Sciences Building 5-14, Edmonton, AB, T6G 2H7, Canada.

View Article
May 2016

Flavivirus Infection Impairs Peroxisome Biogenesis and Early Antiviral Signaling.

J Virol 2015 Dec 30;89(24):12349-61. Epub 2015 Sep 30.

Department of Cell Biology, University of Alberta, Edmonton, Canada Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Canada Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Canada

View Article
December 2015

Signaling dynamics and peroxisomes.

Curr Opin Cell Biol 2015 Aug 29;35:131-6. Epub 2015 May 29.

Center for Infectious Disease Research, formerly Seattle Biomedical Research Institute, Seattle, USA; Institute for Systems Biology, Seattle, USA. Electronic address:

View Article
August 2015

An ancestral role in peroxisome assembly is retained by the divisional peroxin Pex11 in the yeast Yarrowia lipolytica.

J Cell Sci 2015 Apr 6;128(7):1327-40. Epub 2015 Feb 6.

Department of Cell Biology, University of Alberta, Edmonton, AB T6G 2H7, Canada

View Article
April 2015

Transport and retention mechanisms govern lipid droplet inheritance in Saccharomyces cerevisiae.

Traffic 2015 Mar 6;16(3):298-309. Epub 2015 Jan 6.

Department of Cell Biology, University of Alberta, Edmonton, Alberta, T6G 2H7, Canada.

View Article
March 2015

Sharing the cell's bounty - organelle inheritance in yeast.

J Cell Sci 2015 Feb 22;128(4):621-30. Epub 2015 Jan 22.

Department of Cell Biology, University of Alberta, Edmonton, AL T6G 2H7, Canada

View Article
February 2015

Origin and spatiotemporal dynamics of the peroxisomal endomembrane system.

Front Physiol 2014 16;5:493. Epub 2014 Dec 16.

Department of Cell Biology, University of Alberta Edmonton, AB, Canada.

View Article
January 2015

Evolutionary mechanisms for establishing eukaryotic cellular complexity.

Trends Cell Biol 2014 Jul 19;24(7):435-42. Epub 2014 Mar 19.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada. Electronic address:

View Article
July 2014

Tombusvirus replication depends on Sec39p endoplasmic reticulum-associated transport protein.

Virology 2013 Dec 14;447(1-2):21-31. Epub 2013 Sep 14.

Department of Plant Pathology, University of Kentucky, Lexington, 201F Plant Science Building, KY 40546, USA.

View Article
December 2013

Doing the math: How yeast cells maintain their peroxisome populations.

Commun Integr Biol 2013 Nov 13;6(6):e26901. Epub 2013 Nov 13.

Department of Cell Biology; University of Alberta; Edmonton, AB Canada.

View Article
November 2013

Dynein light chain interaction with the peroxisomal import docking complex modulates peroxisome biogenesis in yeast.

J Cell Sci 2013 Oct 13;126(Pt 20):4698-706. Epub 2013 Aug 13.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
October 2013

An ER-peroxisome tether exerts peroxisome population control in yeast.

EMBO J 2013 Sep 30;32(18):2439-53. Epub 2013 Jul 30.

Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.

View Article
September 2013

PEX7 and EBP50 target iNOS to the peroxisome in hepatocytes.

Nitric Oxide 2013 May 5;31:9-19. Epub 2013 Mar 5.

Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

View Article
May 2013

Chaperone proteins select and maintain [PIN+] prion conformations in Saccharomyces cerevisiae.

J Biol Chem 2013 Jan 12;288(2):1266-76. Epub 2012 Nov 12.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
January 2013

Emergent complexity in Myosin V-based organelle inheritance.

Mol Biol Evol 2012 Mar 31;29(3):975-84. Epub 2011 Oct 31.

Department of Cell Biology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

View Article
March 2012

A Drosophila model for the Zellweger spectrum of peroxisome biogenesis disorders.

Dis Model Mech 2011 Sep 13;4(5):659-72. Epub 2011 Jun 13.

Department of Cell Biology, University of Alberta, Edmonton, AB T6G 2H7, Canada.

View Article
September 2011

The peroxin Pex34p functions with the Pex11 family of peroxisomal divisional proteins to regulate the peroxisome population in yeast.

Mol Biol Cell 2011 May 25;22(10):1727-38. Epub 2011 Mar 25.

Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada Institute for Systems Biology, Seattle, WA 98103, USA.

View Article
May 2011

Peroxisome biogenesis: something old, something new, something borrowed.

Physiology (Bethesda) 2010 Dec;25(6):347-56

Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.

View Article
December 2010

Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes.

Mol Biol Cell 2010 Oct 25;21(20):3567-77. Epub 2010 Aug 25.

Department of Medicine, Immunology, Microbiology, and Genome Sciences, University of Washington, Seattle, WA 98195, USA.

View Article
October 2010

Molecular mechanisms of organelle inheritance: lessons from peroxisomes in yeast.

Nat Rev Mol Cell Biol 2010 Sep 18;11(9):644-54. Epub 2010 Aug 18.

Department of Cell Biology, University of Alberta, Edmonton, Alberta, T6G 2H7, Canada.

View Article
September 2010

Dynamic changes in the subcellular distribution of Gpd1p in response to cell stress.

J Biol Chem 2010 Feb 21;285(9):6739-49. Epub 2009 Dec 21.

Institute for Systems Biology, Seattle, Washington 98103, USA.

View Article
February 2010

Phosphorylation-dependent activation of peroxisome proliferator protein PEX11 controls peroxisome abundance.

J Biol Chem 2010 Feb 22;285(9):6670-80. Epub 2009 Dec 22.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
February 2010

Pex3 peroxisome biogenesis proteins function in peroxisome inheritance as class V myosin receptors.

J Cell Biol 2009 Oct 12;187(2):233-46. Epub 2009 Oct 12.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
October 2009

Myosin-driven peroxisome partitioning in S. cerevisiae.

J Cell Biol 2009 Aug 17;186(4):541-54. Epub 2009 Aug 17.

Department of Cell Biology and 2 Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G2H7, Canada.

View Article
August 2009

Endoplasmic reticulum-associated secretory proteins Sec20p, Sec39p, and Dsl1p are involved in peroxisome biogenesis.

Eukaryot Cell 2009 Jun 3;8(6):830-43. Epub 2009 Apr 3.

Department of Cell Biology, University of Alberta, Medical Sciences Building 5-14, Edmonton, Alberta T6G 2H7, Canada.

View Article
June 2009

Spatiotemporal dynamics of the ER-derived peroxisomal endomembrane system.

Int Rev Cell Mol Biol 2009 ;272:191-244

Department of Biology, Concordia University, Montreal, Quebec, Canada.

View Article
February 2009

Dysferlin domain-containing proteins, Pex30p and Pex31p, localized to two compartments, control the number and size of oleate-induced peroxisomes in Pichia pastoris.

Mol Biol Cell 2008 Mar 19;19(3):885-98. Epub 2007 Dec 19.

Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093-0322, USA.

View Article
March 2008

Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers.

Curr Biol 2008 Jan;18(2):102-8

Lipoproteins and Atherosclerosis Group, University of Ottawa Heart Institute, 40 Ruskin St., Ottawa, Ontario K1Y 4W7, Canada.

View Article
January 2008

Maintaining peroxisome populations: a story of division and inheritance.

Annu Rev Cell Dev Biol 2007 ;23:321-44

Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.

View Article
December 2007

Orchestrating organelle inheritance in Saccharomyces cerevisiae.

Curr Opin Microbiol 2007 Dec;10(6):528-38

Department of Cell Biology, University of Alberta, Medical Sciences Building 5-14, Edmonton, Alberta T6G 2H7, Canada.

View Article
December 2007

Peroxisomal peripheral membrane protein YlInp1p is required for peroxisome inheritance and influences the dimorphic transition in the yeast Yarrowia lipolytica.

Eukaryot Cell 2007 Sep 20;6(9):1528-37. Epub 2007 Jul 20.

Department of Cell Biology, University of Alberta, MSB 5-14, Edmonton, Alberta T6G 2H7, Canada.

View Article
September 2007

Sharing the wealth: peroxisome inheritance in budding yeast.

Biochim Biophys Acta 2006 Dec 22;1763(12):1669-77. Epub 2006 Aug 22.

Department of Cell Biology, University of Alberta, Medical Sciences Building 5-14, Edmonton, Alberta, Canada T6G 2H7.

View Article
December 2006

Expression and functional profiling reveal distinct gene classes involved in fatty acid metabolism.

Mol Syst Biol 2006 21;2:2006.0009. Epub 2006 Feb 21.

Institute for Systems Biology, Yeast Group, Seattle, WA 98103-8904, USA.

View Article
August 2006

The dynamin-like protein Vps1p of the yeast Saccharomyces cerevisiae associates with peroxisomes in a Pex19p-dependent manner.

J Biol Chem 2006 May 6;281(18):12817-23. Epub 2006 Mar 6.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
May 2006

Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals.

J Biol Chem 2006 May 21;281(21):14805-12. Epub 2006 Mar 21.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
May 2006

Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae.

J Biol Chem 2005 Oct 8;280(41):34933-9. Epub 2005 Aug 8.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
October 2005

Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae.

J Cell Biol 2005 Jun 31;169(5):765-75. Epub 2005 May 31.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
June 2005

A new definition for the consensus sequence of the peroxisome targeting signal type 2.

J Mol Biol 2004 Jul;341(1):119-34

Department of Cell Biology, University of Alberta, Medical Sciences Building 5-14, Edmonton, Alta., Canada T6G 2H7.

View Article
July 2004

Lack of peroxisomal catalase causes a progeric phenotype in Caenorhabditis elegans.

J Biol Chem 2004 May 2;279(19):19996-20001. Epub 2004 Mar 2.

Department of Cell Biology, University of Alberta, Medical Sciences Building 5-14, Edmonton, Alberta T6G 2H7, Canada.

View Article
May 2004

The peroxisome: orchestrating important developmental decisions from inside the cell.

J Cell Biol 2004 Mar 23;164(5):641-5. Epub 2004 Feb 23.

Department of Biology, Concordia University, 7141 Sherbrooke St., West SP Building, Room SP-501-9, Montreal, Quebec H4B 1R6, Canada.

View Article
March 2004

Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae.

Mol Biol Cell 2004 Feb 14;15(2):665-77. Epub 2003 Nov 14.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
February 2004

Peroxisome division in the yeast Yarrowia lipolytica is regulated by a signal from inside the peroxisome.

J Cell Biol 2003 Sep 22;162(7):1255-66. Epub 2003 Sep 22.

Department of Biology, Concordia University, Montreal, Quebec H4B 1R6, Canada.

View Article
September 2003

YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae.

J Cell Biol 2003 Apr 21;161(2):321-32. Epub 2003 Apr 21.

Department of Cell Biology, University of Alberta, Medical Sciences Building 5-14, Edmonton, Alberta T6G 2H7, Canada.

View Article
April 2003

YlBMH1 encodes a 14-3-3 protein that promotes filamentous growth in the dimorphic yeast Yarrowia lipolytica.

Microbiology 2002 Nov;148(Pt 11):3725-35

Department of Cell Biology, University of Alberta, Medical Sciences Building 5-14, Edmonton, Alberta T6G 2H7, Canada.

View Article
November 2002

RNA interference of peroxisome-related genes in C. elegans: a new model for human peroxisomal disorders.

Physiol Genomics 2002 Aug 14;10(2):79-91. Epub 2002 Aug 14.

Department of Cell Biology, University of Alberta, Edmonton T6G 2H7, Canada.

View Article
August 2002

Isolation and characterization of YlBEM1, a gene required for cell polarization and differentiation in the dimorphic yeast Yarrowia lipolytica.

Eukaryot Cell 2002 Aug;1(4):526-37

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
August 2002

Acyl-CoA oxidase is imported as a heteropentameric, cofactor-containing complex into peroxisomes of Yarrowia lipolytica.

J Cell Biol 2002 Feb 28;156(3):481-94. Epub 2002 Jan 28.

Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

View Article
February 2002