Richard A Lempicki

Richard A Lempicki

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Richard A Lempicki

Publications by authors named "Richard A Lempicki"

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Characterization of chemokine and chemokine receptor expression during Pneumocystis infection in healthy and immunodeficient mice.

Microbes Infect 2015 Sep 5;17(9):638-50. Epub 2015 Jun 5.

Critical Care Medicine Department, NIH Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2015.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554965PMC
September 2015

Differential Specificity of Interferon-alpha Inducible Gene Expression in Association with Human Immunodeficiency Virus and Hepatitis C Virus Levels and Declines .

J AIDS Clin Res 2015;6(1)

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Center Dr., Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4172/2155-6113.1000410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456029PMC
January 2015

Interferon stimulated exonuclease gene 20 kDa links psychiatric events to distinct hepatitis C virus responses in human immunodeficiency virus positive patients.

J Med Virol 2014 Aug 30;86(8):1323-31. Epub 2014 Apr 30.

Department of Gastroenterology and Hepatology, University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.

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http://dx.doi.org/10.1002/jmv.23956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114765PMC
August 2014

Clearance of Pneumocystis murina infection is not dependent on MyD88.

Microbes Infect 2014 Jun 25;16(6):522-7. Epub 2014 Mar 25.

Critical Care Medicine Department, NIH Clinical Center, NIH, Building 10, Room 2C145, MSC 1662, Bethesda, MD 20892-1662, USA. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2014.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071138PMC
June 2014

Hepatitis C-associated mixed cryoglobulinemic vasculitis induces differential gene expression in peripheral mononuclear cells.

Front Immunol 2014 27;5:248. Epub 2014 May 27.

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services , Bethesda, MD , USA.

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http://dx.doi.org/10.3389/fimmu.2014.00248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034044PMC
June 2014

Lifespan of effector memory CD4+ T cells determined by replication-incompetent integrated HIV-1 provirus.

AIDS 2014 May;28(8):1091-9

aClinical and Molecular Retrovirology Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda bClinical Services Program, Applied and Development Research Directorate, Leidos Biomedical Research Incorporated, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000223DOI Listing
May 2014

Interleukin-27 is a potent inhibitor of cis HIV-1 replication in monocyte-derived dendritic cells via a type I interferon-independent pathway.

PLoS One 2013 20;8(3):e59194. Epub 2013 Mar 20.

Applied and Developmental Research Directorate (ADD), Science Application International Corporation (SAIC)-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0059194PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604098PMC
September 2013

Interleukin-27 treated human macrophages induce the expression of novel microRNAs which may mediate anti-viral properties.

Biochem Biophys Res Commun 2013 May 25;434(2):228-34. Epub 2013 Mar 25.

Applied and Developmental Research Directorate, Science Application International Corporation (SAIC)-Frederick, Inc., Frederick National Laboratory for Cancer Research (FNLCR), Frederick, MD 21702, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X130046
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http://dx.doi.org/10.1016/j.bbrc.2013.03.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700531PMC
May 2013

IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation.

J Exp Med 2013 Mar 4;210(3):517-34. Epub 2013 Mar 4.

Applied and Developmental Directorate, Science Applications International Corporation-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1084/jem.20120572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600911PMC
March 2013

Differential gene and microRNA expression between etoposide resistant and etoposide sensitive MCF7 breast cancer cell lines.

PLoS One 2012 18;7(9):e45268. Epub 2012 Sep 18.

Laboratory of Experimental Immunology, Cancer and Inflammation Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0045268PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445463PMC
February 2013

The CD8+ HLA-DR+ T cells expanded in HIV-1 infection are qualitatively identical to those from healthy controls.

Eur J Immunol 2012 Oct 6;42(10):2608-20. Epub 2012 Aug 6.

Clinical and Molecular Retrovirology Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1002/eji.201142046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818066PMC
October 2012

DAVID-WS: a stateful web service to facilitate gene/protein list analysis.

Bioinformatics 2012 Jul 27;28(13):1805-6. Epub 2012 Apr 27.

Laboratory of Immunopathogenesis and Bioinformatics, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1093/bioinformatics/bts251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381967PMC
July 2012

Host gene expression changes correlating with anti-HIV-1 effects in human subjects after treatment with peginterferon Alfa-2a.

J Infect Dis 2012 May 26;205(9):1443-7. Epub 2012 Mar 26.

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/infdis/jis211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324397PMC
May 2012

Cytokine/chemokine patterns connect host and viral characteristics with clinics during chronic hepatitis C.

Eur J Med Res 2012 May 11;17. Epub 2012 May 11.

Department of Gastroenterology and Hepatology, University Hospital of Essen, Germany.

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http://dx.doi.org/10.1186/2047-783X-17-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489717PMC
May 2012

CCL5: a double-edged sword in host defense against the hepatitis C virus.

Int Rev Immunol 2011 Oct-Dec;30(5-6):366-78

Laboratory of Immunopathogenesis and Bioinformatics, SAIC-Frederick Inc., National Cancer Institute at Frederick (NCI-Frederick), Frederick, Maryland, USA.

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http://dx.doi.org/10.3109/08830185.2011.593105DOI Listing
March 2012

Interleukin-27 induces interferon-inducible genes: analysis of gene expression profiles using Affymetrix microarray and DAVID.

Methods Mol Biol 2012 ;820:25-53

Laboratory of Human Retrovirology, Clinical Services Programs (CSP), Applied Developmental Directorate (ADD), Science Applications International Corporation (SAIC)-Frederick, Inc., National Cancer Institute (NCI)-Frederick, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1007/978-1-61779-439-1_3DOI Listing
March 2012

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.

BMC Mol Biol 2011 Sep 16;12:41. Epub 2011 Sep 16.

Laboratory of Molecular Cell Biology, SAIC-Frederick, National Cancer Institute, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1186/1471-2199-12-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187726PMC
September 2011

Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN.

J Immunol 2011 Apr 11;186(8):4541-5. Epub 2011 Mar 11.

Applied and Developmental Research Directorate, Science Applications International Corporation-Frederick, Inc., National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://dx.doi.org/10.4049/jimmunol.1003389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720676PMC
April 2011

Gene duplications in prokaryotes can be associated with environmental adaptation.

BMC Genomics 2010 Oct 20;11:588. Epub 2010 Oct 20.

Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1186/1471-2164-11-588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091735PMC
October 2010

Pre-gastrula expression of zebrafish extraembryonic genes.

BMC Dev Biol 2010 Apr 27;10:42. Epub 2010 Apr 27.

Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1186/1471-213X-10-42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873407PMC
April 2010

Extracting biological meaning from large gene lists with DAVID.

Curr Protoc Bioinformatics 2009 Sep;Chapter 13:Unit 13.11

National Cancer Institute at Frederick, Frederick, Maryland, USA.

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http://dx.doi.org/10.1002/0471250953.bi1311s27DOI Listing
September 2009

Association of interleukin-15-induced peripheral immune activation with hepatic stellate cell activation in persons coinfected with hepatitis C virus and HIV.

J Infect Dis 2009 Aug;200(4):619-23

Department of Transfusion Medicine, National Institutes of Health, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892-1876, USA.

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http://dx.doi.org/10.1086/600107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806092PMC
August 2009

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.

Nat Protoc 2009 ;4(1):44-57

Laboratory of Immunopathogenesis and Bioinformatics, Clinical Services Program, SAIC-Frederick Inc., National Cancer Institute at Frederick, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1038/nprot.2008.211DOI Listing
March 2009

Gene expression patterns induced by HPV-16 L1 virus-like particles in leukocytes from vaccine recipients.

J Immunol 2009 Feb;182(3):1706-29

HPV Immunology Laboratory, Science Applications International Corporation-Frederick/National Cancer Institute-Frederick, Frederick, MD 21702, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701477PMC
http://dx.doi.org/10.4049/jimmunol.182.3.1706DOI Listing
February 2009

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists.

Nucleic Acids Res 2009 Jan 25;37(1):1-13. Epub 2008 Nov 25.

Laboratory of Immunopathogenesis and Bioinformatics, Clinical Services Program, SAIC-Frederick, Inc., National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkn923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615629PMC
January 2009

IL-27, a novel anti-HIV cytokine, activates multiple interferon-inducible genes in macrophages.

AIDS 2008 Jan;22(1):39-45

Laboratory of Human Retrovirology, National Cancer Institute at Frederick, Frederick, Maryland, USA.

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http://dx.doi.org/10.1097/QAD.0b013e3282f3356cDOI Listing
January 2008

DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis.

BMC Bioinformatics 2007 Nov 2;8:426. Epub 2007 Nov 2.

Laboratory of Immunopathogenesis and Bioinformatics, Clinical Services Program, SAIC-Frederick, Inc., National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-8-426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186358PMC
November 2007

Immunodeficiency and intrinsic IFN resistance are associated with viral breakthrough to HCV therapy in HIV-coinfected patients.

AIDS Res Hum Retroviruses 2007 Nov;23(11):1354-9

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA.

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http://www.liebertpub.com/doi/10.1089/aid.2007.0091
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http://dx.doi.org/10.1089/aid.2007.0091DOI Listing
November 2007

Zap70 signaling pathway mediates glucocorticoid receptor-dependent transcriptional activation: role in the regulation of annexin 1 expression in T cells.

J Immunol 2007 Sep;179(6):3851-8

Laboratory of Molecular Cell Biology, SAIC-Frederick, National Cancer Institute, Frederick, MD 21702, USA.

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http://dx.doi.org/10.4049/jimmunol.179.6.3851DOI Listing
September 2007

DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists.

Nucleic Acids Res 2007 Jul 18;35(Web Server issue):W169-75. Epub 2007 Jun 18.

Laboratory of Immunopathogenesis and Bioinformatics, SAIC-Frederick, Inc., National Cancer Institute at Frederick, MD 21702, USA.

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http://dx.doi.org/10.1093/nar/gkm415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933169PMC
July 2007

Noninfectious papilloma virus-like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27.

Blood 2007 Mar 26;109(5):1841-9. Epub 2006 Oct 26.

Laboratory of Human Retrovirology, Clinical Services Program (CSP), Science Applications International Corporation (SAIC)-Frederick, National Cancer Institute (NCI), MD, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2006-02-00
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http://dx.doi.org/10.1182/blood-2006-02-001578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1801045PMC
March 2007

Diminished production of monocyte proinflammatory cytokines during human immunodeficiency virus viremia is mediated by type I interferons.

J Virol 2006 Dec 27;80(23):11486-97. Epub 2006 Sep 27.

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases/NIH, Bldg 10, Rm 11B-09, 10 Center Drive, Bethesda, MD 20892-1876, USA.

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http://dx.doi.org/10.1128/JVI.00324-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1642603PMC
December 2006

Long homopurine*homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region.

Nucleic Acids Res 2006 19;34(9):2663-75. Epub 2006 May 19.

Institute of Biosciences and Technology, Center for Genome Research, Texas A&M University System Health Science Center, Texas Medical Center, 2121 West Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/nar/gkl354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464109PMC
May 2006

R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells.

Proc Natl Acad Sci U S A 2006 Mar 27;103(10):3746-51. Epub 2006 Feb 27.

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0511237103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533779PMC
March 2006

HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells.

Virology 2006 Feb 2;345(1):105-14. Epub 2005 Nov 2.

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1876, USA.

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http://dx.doi.org/10.1016/j.virol.2005.09.052DOI Listing
February 2006

Retinoic acid-induced downmodulation of telomerase activity in human cancer cells.

Exp Mol Pathol 2005 Oct;79(2):108-17

Protein Interactions Group, Laboratory of Experimental and Computational Biology, NCI-Frederick, NIH, Bldg. 469, Rm. 139, P.O. Box B, Miller Drive, Frederick, MD 21702-1201, USA.

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http://dx.doi.org/10.1016/j.yexmp.2005.06.001DOI Listing
October 2005

Identifying biological themes within lists of genes with EASE.

Genome Biol 2003 11;4(10):R70. Epub 2003 Sep 11.

Laboratory of Immunopathogenesis and Bioinformatics, PO Box B, SAIC-Frederick, Inc, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1186/gb-2003-4-10-r70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC328459PMC
August 2004

PubMatrix: a tool for multiplex literature mining.

BMC Bioinformatics 2003 Dec 10;4:61. Epub 2003 Dec 10.

Gene Expression and Genomics Unit, National Institutes of Health, Baltimore, MD, USA.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-4-61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC317283PMC
December 2003

Evaluation of gene expression measurements from commercial microarray platforms.

Nucleic Acids Res 2003 Oct;31(19):5676-84

Microarray Core Laboratory, National Institute of Diabetes and Digestive and Kidney Disorders, National Institutes of Health, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC206463PMC
http://dx.doi.org/10.1093/nar/gkg763DOI Listing
October 2003

DAVID: Database for Annotation, Visualization, and Integrated Discovery.

Genome Biol 2003 3;4(5):P3. Epub 2003 Apr 3.

Science Applications International Corporation-Frederick, Clinical Services Program, Laboratory of Immunopathogenesis and Bioinformatics, National Cancer Institute at Frederick, MD 21702, USA.

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July 2003

Gene expression and viral prodution in latently infected, resting CD4+ T cells in viremic versus aviremic HIV-infected individuals.

Proc Natl Acad Sci U S A 2003 Feb 27;100(4):1908-13. Epub 2003 Jan 27.

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0437640100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149932PMC
February 2003

Cutting edge: L-selectin (CD62L) expression distinguishes small resting memory CD4+ T cells that preferentially respond to recall antigen.

J Immunol 2003 Jan;170(1):28-32

Division of Infectious Diseases, Department of Medicine, Georgetown University School of Medicine, Washington, DC 20053, USA.

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http://dx.doi.org/10.4049/jimmunol.170.1.28DOI Listing
January 2003

Telomere length and heavy-chain mutation status in familial chronic lymphocytic leukemia.

Leuk Res 2002 Sep;26(9):791-4

Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, MSC 7236, Rockville, MD 20892, USA.

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http://dx.doi.org/10.1016/s0145-2126(02)00010-3DOI Listing
September 2002