Publications by authors named "Richard A Lang"

87Publications

Retinal ganglion cell interactions shape the developing mammalian visual system.

Development 2020 12 7;147(23). Epub 2020 Dec 7.

The Visual Systems Group, Cincinnati Children's Hospital, Cincinnati, OH 45229, USA.

View Article and Find Full Text PDF
December 2020

Opsin 3-G Promotes Airway Smooth Muscle Relaxation Modulated by G Protein Receptor Kinase 2.

Am J Respir Cell Mol Biol 2021 Jan;64(1):59-68

Department of Anesthesiology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York.

View Article and Find Full Text PDF
January 2021

Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing.

Cell Rep 2020 01;30(3):672-686.e8

Center for Chronobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; The Visual Systems Group, Abrahamson Pediatric Eye Institute, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Ophthalmology, University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA. Electronic address:

View Article and Find Full Text PDF
January 2020

Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin.

Curr Biol 2019 10 10;29(20):3478-3487.e4. Epub 2019 Oct 10.

Department of Ophthalmology, Campus Box 358058, University of Washington School of Medicine, 750 Republican St., Seattle, WA 98109, USA; Department of Biological Structure and Department of Pathology, University of Washington School of Medicine, 750 Republican St., Seattle, WA 98109, USA.

View Article and Find Full Text PDF
October 2019

An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye.

Nat Cell Biol 2019 04 1;21(4):420-429. Epub 2019 Apr 1.

The Visual Systems Group, Abrahamson Pediatric Eye Institute, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

View Article and Find Full Text PDF
April 2019

YAP/TAZ-CDC42 signaling regulates vascular tip cell migration.

Proc Natl Acad Sci U S A 2017 10 25;114(41):10918-10923. Epub 2017 Sep 25.

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229;

View Article and Find Full Text PDF
October 2017

Myeloid Wnt ligands are required for normal development of dermal lymphatic vasculature.

PLoS One 2017 28;12(8):e0181549. Epub 2017 Aug 28.

Visual Systems Group, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.

View Article and Find Full Text PDF
October 2017

CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth.

Biochem J 2016 10 26;473(19):3291-305. Epub 2016 Jul 26.

Division of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH 45267, USA.

View Article and Find Full Text PDF
October 2016

The Eyes Absent Proteins in Developmental and Pathological Angiogenesis.

Am J Pathol 2016 Mar 5;186(3):568-78. Epub 2016 Jan 5.

Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address:

View Article and Find Full Text PDF
March 2016

Crim1 regulates integrin signaling in murine lens development.

Development 2016 Jan 17;143(2):356-66. Epub 2015 Dec 17.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA

View Article and Find Full Text PDF
January 2016

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury.

Fibrogenesis Tissue Repair 2015 15;8:19. Epub 2015 Oct 15.

Centre for Liver Disease Research, School of Medicine, The University of Queensland, Translational Research Institute, 37 Kent St, Brisbane, 4102 Australia.

View Article and Find Full Text PDF
October 2015

Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea.

Proc Natl Acad Sci U S A 2015 Oct 21;112(42):13093-8. Epub 2015 Sep 21.

Department of Ophthalmology, University of Washington Medical School, Seattle, WA 98104; Department of Biological Structure, University of Washington Medical School, Seattle, WA 98104; Department of Pathology, University of Washington Medical School, Seattle, WA 98104

View Article and Find Full Text PDF
October 2015

FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis.

J Exp Med 2015 Aug 10;212(9):1433-48. Epub 2015 Aug 10.

MRC and University of Edinburgh Centre for Reproductive Health, Queen's Medical Research Institute; and Edinburgh Cancer Research UK Centre, MRC Institute of Genetics and Molecular Medicine; University of Edinburgh, Edinburgh EH16 4TJ, Scotland, UK Department of Developmental and Molecular Biology and Department of Biochemistry, Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461

View Article and Find Full Text PDF
August 2015