Richard A Knight

Richard A Knight

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Richard A Knight

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Integrin-β4 is a novel transcriptional target of TAp73.

Cell Cycle 2018 8;17(5):589-594. Epub 2018 Feb 8.

a MRC Toxicology Unit , Hodgkin Building , Lancaster Road, Leicester LE1 9HN , United Kingdom.

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http://dx.doi.org/10.1080/15384101.2017.1403684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969564PMC
September 2019

American Association of Kidney Patients survey of patient preferences for hemodialysis vascular access.

J Vasc Access 2019 Aug 29:1129729819870962. Epub 2019 Aug 29.

5 American Association of Kidney Patients, Tampa, FL, USA.

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http://dx.doi.org/10.1177/1129729819870962DOI Listing
August 2019

ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma.

Proc Natl Acad Sci U S A 2018 07 25;115(28):7356-7361. Epub 2018 Jun 25.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", 00133 Rome, Italy;

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http://dx.doi.org/10.1073/pnas.1801435115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048510PMC
July 2018

TAp73 contributes to the oxidative stress response by regulating protein synthesis.

Proc Natl Acad Sci U S A 2018 06 29;115(24):6219-6224. Epub 2018 May 29.

Medical Research Council, Toxicology Unit, University of Cambridge, Leicester LE1 9HN, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1718531115DOI Listing
June 2018

p73 Regulates Primary Cortical Neuron Metabolism: a Global Metabolic Profile.

Mol Neurobiol 2018 Apr 6;55(4):3237-3250. Epub 2017 May 6.

Department of Cancer Studies, University of Leicester, Leicester, LE2 7LX, UK.

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http://dx.doi.org/10.1007/s12035-017-0517-3DOI Listing
April 2018

An Evolving Continuum of Care for the Kidney Disease Patient Will Help the Transplant Center Patient Navigator.

Authors:
Richard A Knight

Clin J Am Soc Nephrol 2018 04 26;13(4):519-520. Epub 2018 Mar 26.

College of Business, Department of Management, Marketing, and Public Administration, Bowie State University, Bowie, Maryland

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http://dx.doi.org/10.2215/CJN.02300218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968903PMC
April 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Polypharmacology of Approved Anticancer Drugs.

Curr Drug Targets 2017 ;18(5):534-543

Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom.

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http://dx.doi.org/10.2174/1389450117666160301095233DOI Listing
September 2017

TAp73 upregulates IL-1β in cancer cells: Potential biomarker in lung and breast cancer?

Biochem Biophys Res Commun 2017 01 3;482(3):498-505. Epub 2017 Feb 3.

MRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.10.085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243147PMC
January 2017

How Does p73 Cause Neuronal Defects?

Mol Neurobiol 2016 09 13;53(7):4509-20. Epub 2015 Aug 13.

Toxicology Unit, Medical Research Council, Leicester, LE1 9HN, UK.

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http://dx.doi.org/10.1007/s12035-015-9381-1DOI Listing
September 2016

Perspective on multi-target antiplatelet therapies: high content phenotypic screening as an unbiased source of novel polypharmacological strategies.

Mini Rev Med Chem 2015 ;15(8):622-9

MRC Toxicology Unit, Hodgkin Building, Leicester University, Lancaster Road, P.O. Box 138, Leicester LE1 9HN, UK.

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http://dx.doi.org/10.2174/1389557515666150219124018DOI Listing
January 2016

Exploration of individuality in drug metabolism by high-throughput metabolomics: The fast line for personalized medicine.

Drug Discov Today 2016 Jan 26;21(1):103-110. Epub 2015 Jul 26.

Medical Research Council, Toxicology Unit, Leicester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2015.07.011DOI Listing
January 2016

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

Proc Natl Acad Sci U S A 2015 Jan 22;112(1):226-31. Epub 2014 Dec 22.

Medical Research Council Toxicology Unit, Leicester LE1 9HN, United Kingdom; Department of Experimental Medicine and Surgery, Biochemistry Istituto Dermopatico dell'Immacolata Laboratory, University of Rome Tor Vergata, 00133 Rome, Italy

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http://www.pnas.org/lookup/doi/10.1073/pnas.1410609111
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http://dx.doi.org/10.1073/pnas.1410609111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291637PMC
January 2015

TAp73 promotes anabolism.

Oncotarget 2014 Dec;5(24):12820-934

Medical Research Council, Toxicology Unit, Leicester University, Leicester LE1 9HN, UK. Department of Cancer Studies, Cancer Research UK, Leicester Centre, University of Leicester, Leicester, LE1 7RH, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350352PMC
http://dx.doi.org/10.18632/oncotarget.2667DOI Listing
December 2014

TAp73 promotes anti-senescence-anabolism not proliferation.

Aging (Albany NY) 2014 Nov;6(11):921-30

Medical Research Council, Toxicology Unit, Leicester LE1 9HN, UK. Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276786PMC
http://dx.doi.org/10.18632/aging.100701DOI Listing
November 2014

Cardiac tissue engineering: renewing the arsenal for the battle against heart disease.

Integr Biol (Camb) 2014 Feb;6(2):111-26

Medical Molecular Biology Unit, University College London, Rayne Building, 5 University Street, London WC1E 6JF, UK.

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http://dx.doi.org/10.1039/c3ib40097bDOI Listing
February 2014

miR-34: from bench to bedside.

Oncotarget 2014 Feb;5(4):872-81

Medical Research Council, Toxicology Unit, Leicester University, Leicester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011589PMC
http://dx.doi.org/10.18632/oncotarget.1825DOI Listing
February 2014

GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation.

Cell Cycle 2013 Nov 10;12(22):3564-73. Epub 2013 Oct 10.

Medical Research Council; Toxicology Unit; Leicester University; Leicester, UK; Institute of Health Sciences; Shanghai Institutes for Biological Sciences; Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine; Shanghai, China.

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http://www.tandfonline.com/doi/abs/10.4161/cc.26771
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http://dx.doi.org/10.4161/cc.26771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906342PMC
November 2013

Signal transducer and activator of transcription-1 localizes to the mitochondria and modulates mitophagy.

JAKSTAT 2013 Oct 15;2(4):e25666. Epub 2013 Jul 15.

Medical Molecular Biology Unit; University College London; London, UK.

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http://dx.doi.org/10.4161/jkst.25666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902047PMC
October 2013

Role of p63 and the Notch pathway in cochlea development and sensorineural deafness.

Proc Natl Acad Sci U S A 2013 Apr 15;110(18):7300-5. Epub 2013 Apr 15.

Biochemistry Laboratory Istituto Dermopatico Dell'Immacolata, c/o Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.1073/pnas.1214498110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645580PMC
April 2013

Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury.

Int J Cardiol 2013 03 24;163(3):326-334. Epub 2011 Oct 24.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2011.08.849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581775PMC
March 2013

NRF2 and p53: Januses in cancer?

Oncotarget 2012 Nov;3(11):1272-83

Leicester University, Leicester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717791PMC
http://dx.doi.org/10.18632/oncotarget.754DOI Listing
November 2012

Necroptosis: STAT3 kills?

JAKSTAT 2012 Jul;1(3):200-2

Medical Molecular Biology Unit; University College London; London, UK.

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http://dx.doi.org/10.4161/jkst.20968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670246PMC
July 2012

STAT transcription in the ischemic heart.

JAKSTAT 2012 Apr;1(2):111-7

Medical Molecular Biology Unit; University College London; London, UK.

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http://dx.doi.org/10.4161/jkst.20078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670290PMC
April 2012

Autophagy in the stress-induced myocardium.

Front Biosci (Elite Ed) 2012 Jan 1;4:2131-41. Epub 2012 Jan 1.

The Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH.

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January 2012

Cell death pathology: cross-talk with autophagy and its clinical implications.

Biochem Biophys Res Commun 2011 Oct 22;414(2):277-81. Epub 2011 Sep 22.

Medical Research Council, Toxicology Unit, Leicester University, Leicester LE1 9HN, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1101684
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http://dx.doi.org/10.1016/j.bbrc.2011.09.080DOI Listing
October 2011

miR-146a is modulated in human endothelial cell with aging.

Atherosclerosis 2011 Aug 5;217(2):326-30. Epub 2011 Apr 5.

Medical Research Council, Toxicology Unit, Leicester University, Leicester LE1 9HN, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.03.034DOI Listing
August 2011

The role of minocycline in ischemia-reperfusion injury: a comprehensive review of an old drug with new implications.

Recent Pat Cardiovasc Drug Discov 2011 May;6(2):123-32

Center for Heart and Vessel Preclinical Studies, St. John Hospital and Medical Center, Wayne State University School of Medicine, USA.

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May 2011

MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines.

Cell Cycle 2011 Apr 1;10(7):1121-31. Epub 2011 Apr 1.

Department of experimental Medicine and Biochemical Sciences and Biochemistry Laboratory IDI-IRCCS, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.4161/cc.10.7.15180DOI Listing
April 2011

Rita's 102!!

Mol Neurobiol 2011 Apr;43(2):77-9

European Brain Research Institute, Rome, Italy.

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http://dx.doi.org/10.1007/s12035-011-8173-5DOI Listing
April 2011

STAT3 modulates the DNA damage response pathway.

Int J Exp Pathol 2010 Dec 27;91(6):506-14. Epub 2010 Aug 27.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London, UK.

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http://dx.doi.org/10.1111/j.1365-2613.2010.00734.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010549PMC
December 2010

p73 regulates maintenance of neural stem cell.

Biochem Biophys Res Commun 2010 Dec 25;403(1):13-7. Epub 2010 Oct 25.

Medical Research Council, Toxicology Unit, Leicester University, Leicester LE1 9HN, UK.

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http://dx.doi.org/10.1016/j.bbrc.2010.10.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041924PMC
December 2010

STAT1 interacts directly with cyclin D1/Cdk4 and mediates cell cycle arrest.

Cell Cycle 2010 Dec 1;9(23):4638-49. Epub 2010 Dec 1.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London, UK.

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http://dx.doi.org/10.4161/cc.9.23.13955DOI Listing
December 2010

New targets of urocortin-mediated cardioprotection.

J Mol Endocrinol 2010 Aug 25;45(2):69-85. Epub 2010 May 25.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London, WC1N 1EH, UK.

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http://dx.doi.org/10.1677/JME-09-0148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069736PMC
August 2010

Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2.

Proc Natl Acad Sci U S A 2010 Jul 6;107(29):12877-82. Epub 2010 Jul 6.

Medical Research Council, Toxicology Unit, Leicester University, Leicester LE1 9HN, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0911828107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919933PMC
July 2010

Green tea polyphenol epigallocatechin gallate inhibits cell signaling by inducing SOCS1 gene expression.

Int Immunol 2010 May 26;22(5):359-66. Epub 2010 Feb 26.

Laboratory of Immune Regulation, Graduate School of Frontier Biosciences, Osaka University, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1093/intimm/dxq015DOI Listing
May 2010

p73 and p63 regulate the expression of fibroblast growth factor receptor 3.

Biochem Biophys Res Commun 2010 Apr 16;394(3):824-8. Epub 2010 Mar 16.

MRC Toxicology Unit, Lancaster Road, Hodgkin Building, Leicester LE1 9HN, UK.

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http://dx.doi.org/10.1016/j.bbrc.2010.03.084DOI Listing
April 2010

Induction of TAp63 by histone deacetylase inhibitors.

Biochem Biophys Res Commun 2010 Jan 30;391(4):1748-51. Epub 2009 Dec 30.

Medical Research Council, Toxicology Unit, Leicester University, Leicester LE1 9HN, UK.

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http://dx.doi.org/10.1016/j.bbrc.2009.12.147DOI Listing
January 2010

STAT3 deletion sensitizes cells to oxidative stress.

Biochem Biophys Res Commun 2009 Jul 18;385(3):324-9. Epub 2009 May 18.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N1EH, UK.

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http://dx.doi.org/10.1016/j.bbrc.2009.05.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706948PMC
July 2009

Caspase cleavage of Itch in chronic lymphocytic leukemia cells.

Biochem Biophys Res Commun 2009 Feb 13;379(3):659-64. Epub 2008 Dec 13.

Medical Research Council, Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester, UK.

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http://dx.doi.org/10.1016/j.bbrc.2008.11.154DOI Listing
February 2009

TAp73alpha binds the kinetochore proteins Bub1 and Bub3 resulting in polyploidy.

Cell Cycle 2009 Feb 12;8(3):421-9. Epub 2009 Feb 12.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.4161/cc.8.3.7623DOI Listing
February 2009

miRNAs, 'stemness' and skin.

Trends Biochem Sci 2008 Dec 8;33(12):583-91. Epub 2008 Oct 8.

Institut national de la santé et de la recherche médicale, University of Nice-Sophia Antipolis, Nice, France.

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http://dx.doi.org/10.1016/j.tibs.2008.09.002DOI Listing
December 2008

FLASH and NPAT positive but not Coilin positive Cajal Bodies correlate with cell ploidy.

Cell Cycle 2008 Aug 21;7(15):2357-67. Epub 2008 May 21.

Department of Experimental Medicine, University of Rome Tor Vergata, Roma, Italy.

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http://www.tandfonline.com/doi/abs/10.4161/cc.6344
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http://dx.doi.org/10.4161/cc.6344DOI Listing
August 2008

ERK and the F-box protein betaTRCP target STAT1 for degradation.

J Biol Chem 2008 Jun 31;283(23):16077-83. Epub 2008 Mar 31.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M800384200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259647PMC
June 2008

p73-mediated transcriptional activity is negatively regulated by polo-like kinase 1.

Cell Cycle 2008 May 15;7(9):1214-23. Epub 2008 Feb 15.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London, United Kingdom.

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http://dx.doi.org/10.4161/cc.7.9.5777DOI Listing
May 2008

Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis.

Proc Natl Acad Sci U S A 2007 Jun 20;104(26):10871-6. Epub 2007 Jun 20.

*Medical Research Council, Toxicology Unit, Leicester University, Leicester LE1 9HN, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0700761104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904122PMC
June 2007

STAT1 regulates p73-mediated Bax gene expression.

FEBS Lett 2007 Mar 1;581(6):1217-26. Epub 2007 Mar 1.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK.

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http://dx.doi.org/10.1016/j.febslet.2007.02.049DOI Listing
March 2007

TAp63 and DeltaNp63 in cancer and epidermal development.

Cell Cycle 2007 Feb 3;6(3):274-85. Epub 2007 Feb 3.

University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.4161/cc.6.3.3797DOI Listing
February 2007

Generation of DeltaTAp73 proteins by translation from a putative internal ribosome entry site.

Ann N Y Acad Sci 2007 Jan;1095:315-24

Medical Research Council Toxicology Unit, Hodgkin Building, Lancaster Road, University of Leicester, Leicester, LE1 9HN United Kingdom.

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http://dx.doi.org/10.1196/annals.1397.035DOI Listing
January 2007

p63 is upstream of IKK alpha in epidermal development.

J Cell Sci 2006 Nov;119(Pt 22):4617-22

Biochemistry Laboratory, IDI-IRCCS, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.03265
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http://dx.doi.org/10.1242/jcs.03265DOI Listing
November 2006

Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury.

FASEB J 2006 Oct 25;20(12):2115-7. Epub 2006 Aug 25.

Department of Medical Molecular Biology, The Institute of Child Health, University College London, 30 Guilford St., London, WC1N 1EH, UK.

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http://www.fasebj.org/content/20/12/2115.full.pdf
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http://www.fasebj.org/cgi/doi/10.1096/fj.06-6188fje
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http://dx.doi.org/10.1096/fj.06-6188fjeDOI Listing
October 2006

The E3 ubiquitin ligase Itch controls the protein stability of p63.

Proc Natl Acad Sci U S A 2006 Aug 14;103(34):12753-8. Epub 2006 Aug 14.

Medical Research Council, Toxicology Unit, Leicester University, Leicester LE1 9HN, United Kingdom.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0603449103
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http://dx.doi.org/10.1073/pnas.0603449103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550770PMC
August 2006

Degradation of p63 by Itch.

Cell Cycle 2006 Aug 15;5(16):1735-9. Epub 2006 Aug 15.

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http://dx.doi.org/10.4161/cc.5.16.3260DOI Listing
August 2006

Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury.

J Mol Cell Cardiol 2006 Jun 12;40(6):846-52. Epub 2006 May 12.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK.

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http://dx.doi.org/10.1016/j.yjmcc.2006.03.428DOI Listing
June 2006

p53 is cleaved by caspases generating fragments localizing to mitochondria.

J Biol Chem 2006 May 10;281(19):13566-73. Epub 2006 Mar 10.

Medical Research Council (MRC) Toxicology Unit, Leicester LE1 9HN, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M512467200DOI Listing
May 2006

[This death which is necessary for life].

J Soc Biol 2005 ;199(3):267-76

INSERM/Université Paris 7, Faculté de Médecine Xavier Bichat, 75870 Paris Cedex 18, France.

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March 2006

Gerry Melino.

Cell Cycle 2005 Aug 7;4(8):995-6. Epub 2005 Aug 7.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London, WC1N 1EH UK.

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http://dx.doi.org/10.4161/cc.4.8.1901DOI Listing
August 2005

p73 induces apoptosis by different mechanisms.

Biochem Biophys Res Commun 2005 Jun;331(3):713-7

Laboratory of Biochemistry and Molecular Biology, IRCCS-Fondazione Santa Lucia, Via Ardeatina 306, 00179 Rome, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2005.03.156DOI Listing
June 2005

New antibodies recognizing p73: comparison with commercial antibodies.

Biochem Biophys Res Commun 2005 Apr;330(1):186-93

Medical Research Council, Toxicology Unit, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.

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April 2005

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.

J Cell Sci 2005 Apr 22;118(Pt 8):1629-39. Epub 2005 Mar 22.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.01728
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April 2005

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73.

Mol Cell Biol 2004 Dec;24(24):10593-610

Medical Research Council, Toxicology Unit, Hodgkin Building, Leicester University, Lancaster Road, P.O. Box 138, Leicester LE1 9HN, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC533962PMC
December 2004

Mechanism of induction of apoptosis by p73 and its relevance to neuroblastoma biology.

Ann N Y Acad Sci 2004 Dec;1028:143-9

Medical Research Council Toxicology Unit, Leicester, United Kingdom.

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December 2004

Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis.

FASEB J 2004 Oct 19;18(13):1621-3. Epub 2004 Aug 19.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London, England.

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October 2004

The cardioprotective effect of urocortin during ischaemia/reperfusion involves the prevention of mitochondrial damage.

Biochem Biophys Res Commun 2004 Aug;321(2):479-86

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK.

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http://dx.doi.org/10.1016/j.bbrc.2004.06.170DOI Listing
August 2004

STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis.

J Biol Chem 2004 Feb 5;279(7):5811-20. Epub 2003 Nov 5.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, United Kingdom.

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February 2004

p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation.

J Biol Chem 2004 Feb 21;279(9):8076-83. Epub 2003 Nov 21.

Biochemistry Laboratory, Instituto Dermopatico Dell'Immacolata-Istituto di Ricovero e Cura a Carattere Scientifico, Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.

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February 2004

p73: in silico evidence for a putative third promoter region.

Biochem Biophys Res Commun 2004 Jan;313(3):765-70

Medical Research Council Toxicology Unit, Hodgkin Building, Lancaster Road, Leicester LE1 9HN, UK.

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January 2004

Functional regulation of p73 and p63: development and cancer.

Trends Biochem Sci 2003 Dec;28(12):663-70

Medical Research Council, Toxicology Unit, LE1 9HN, Leicester, UK.

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http://dx.doi.org/10.1016/j.tibs.2003.10.004DOI Listing
December 2003

The p53 homology trap.

Cancer Biol Ther 2003 Jan-Feb;2(1):63-6

Deportment of Cystic Fibrosis, National Heart and Lung Institute, Imperial College, London UK.

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http://dx.doi.org/10.4161/cbt.192DOI Listing
July 2003

Human rhinovirus selectively modulates membranous and soluble forms of its intercellular adhesion molecule-1 (ICAM-1) receptor to promote epithelial cell infectivity.

J Biol Chem 2003 Apr 26;278(14):11954-61. Epub 2003 Jan 26.

Lung Injury and Inflammation Research, Directorate of Respiratory Medicine, North Staffordshire Hospital Trust, Stoke-on-Trent ST4 6QG, United Kingdom.

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April 2003

The carboxyl-terminal activation domain of the STAT-1 transcription factor enhances ischemia/reperfusion-induced apoptosis in cardiac myocytes.

FASEB J 2002 Nov 5;16(13):1841-3. Epub 2002 Sep 5.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London WC1N 1EH, UK.

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November 2002

Antiapoptotic activity of the free caspase recruitment domain of procaspase-9: a novel endogenous rescue pathway in cell death.

J Biol Chem 2002 Apr 1;277(16):13693-9. Epub 2002 Feb 1.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, United Kingdom.

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April 2002

Osmotic resistance of high-density erythrocytes in transglutaminase 2-deficient mice.

Biochem Biophys Res Commun 2002 Mar;291(5):1123-7

Biochemistry Laboratory, c/o Department of Experimental Medicine, University of Rome Tor Vergata, Via Tor Vergata 135, 00133 Rome, Italy.

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March 2002