Richard A Graham

Richard A Graham

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Richard A Graham

Richard A Graham

Publications by authors named "Richard A Graham"

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A survey of renal impairment pharmacokinetic studies for new oncology drug approvals in the USA from 2010 to early 2015: a focus on development strategies and future directions.

Anticancer Drugs 2017 08;28(7):677-701

aClovis Oncology bMedivation Inc., San Francisco cGenentech Inc. dTheravance Biopharma Inc., South San Francisco, California, USA.

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http://dx.doi.org/10.1097/CAD.0000000000000513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515635PMC
August 2017

A survey of new oncology drug approvals in the USA from 2010 to 2015: a focus on optimal dose and related postmarketing activities.

Cancer Chemother Pharmacol 2016 Mar 25;77(3):459-76. Epub 2016 Jan 25.

Department of Clinical Pharmacology, Genentech, Inc., 1 DNA Way, MS 463A, South San Francisco, CA, 94080, USA.

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http://dx.doi.org/10.1007/s00280-015-2931-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767861PMC
March 2016

Cloning, tissue expression, and regulation of beagle dog CYP4A genes.

Toxicol Sci 2006 Aug 4;92(2):356-67. Epub 2006 May 4.

Division of Molecular Pharmaceutics, School of Pharmacy, The University of North Carolina at Chapel Hill, 27599, USA.

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http://dx.doi.org/10.1093/toxsci/kfl009DOI Listing
August 2006

Temporal kinetics and concentration-response relationships for induction of CYP1A, CYP2B, and CYP3A in primary cultures of beagle dog hepatocytes.

J Biochem Mol Toxicol 2006 ;20(2):69-78

Division of Molecular Pharmaceutics, School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1002/jbt.20118DOI Listing
June 2006

Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells.

J Pharmacol Exp Ther 2005 Dec 31;315(3):1256-64. Epub 2005 Aug 31.

Division of Drug Delivery and Disposition, School of Pharmacy, CB 7360, Kerr Hall, Room 2319, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7360, USA.

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http://dx.doi.org/10.1124/jpet.105.090795DOI Listing
December 2005

In vivo and in vitro induction of cytochrome P450 enzymes in beagle dogs.

Drug Metab Dispos 2002 Nov;30(11):1206-13

XenoTech, LLC, Lenexa, Kansas 66219, USA.

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http://dx.doi.org/10.1124/dmd.30.11.1206DOI Listing
November 2002