Publications by authors named "Riccardo D"

4 Publications

  • Page 1 of 1

Comparison between osteoblasts derived from human dental pulp stem cells and osteosarcoma cell lines.

Cell Biol Int 2008 Jul 4;32(7):733-8. Epub 2008 Mar 4.

Centre of Molecular Genetics, CARISBO Foundation, Institute of Histology and General Embryology, School of Medicine, University of Bologna, Bologna, Italy.

Stem cells derived from human dental pulp are able to differentiate into osteoblasts and are a potential source of autologous bone. The aim of this study was to compare genes differentially expressed in osteoblastoids from human dental pulp (OHDP) to osteosarcoma cells (OCs). Human dental pulp was extracted and immersed in a digestive solution. Cells were cultured and selected using c-kit, CD34, CD45 and STRO-1 antibodies. In parallel, two OCs (i.e., SAOS2 and TE85) were cultured. RNA was extracted from different populations of cells and cDNA was used for the hybridisation of human 19.2K DNA microarrays. We identified several differences in gene expression between OHDP and OCs. Some down-regulated OHDP genes, such as RUNX1, MAP4K4 and PRDM2, are involved in bone development, cell motility and transcript regulation. Gene expression in OHDP is significantly different from that in OCs, suggesting differences in cell function and activity between these cells.
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http://dx.doi.org/10.1016/j.cellbi.2008.02.003DOI Listing
July 2008

Simulation of the biomechanical behavior of the skin in virtual surgical applications by finite element method.

IEEE Trans Biomed Eng 2005 Sep;52(9):1514-21

Department of Communication, Computer and System Sciences, University of Genoa, 16145 Genoa, Italy.

The objective of this study was to develop a software application that is able to support plastic surgeons interested in applying simulations and soft tissue modeling during presurgical planning activities. By using our user-friendly interface and force-displacement graphs, users can analyze scalp skin behaviors when subjected to stress. Users can 1) determine the dynamic of a general point of scalp skin after the application of a specific force, 2) predict the force needed for displacement of a point, and 3) study the deformation of all the points of the entire scalp based on the force applied. Results showed how users are able to manipulate and analyze mechanical behaviors on a mechanical model rather than on a pure geometric qualitative physiological model. The entire application was developed on a Silicon Graphics workstation.
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http://dx.doi.org/10.1109/TBME.2005.851529DOI Listing
September 2005

Ulnar deviation of the thumb: an exceptional finding in Rubinstein-Taybi syndrome.

Clin Dysmorphol 2000 Jul;9(3):231-2

A 2-year-old girl with Rubinstein-Taybi syndrome and the unusual finding of ulnar deviation of the thumb is described. Possible modes of inheritance are discussed.
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http://dx.doi.org/10.1097/00019605-200009030-00016DOI Listing
July 2000