Publications by authors named "Rhine R Shen"

15Publications

The Tyrosine Kinase Adaptor Protein FRS2 Is Oncogenic and Amplified in High-Grade Serous Ovarian Cancer.

Mol Cancer Res 2015 Mar 3;13(3):502-9. Epub 2014 Nov 3.

Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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March 2015

Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.

Cancer Discov 2014 Apr 20;4(4):452-65. Epub 2014 Jan 20.

Departments of 1Medical Oncology and 2Cancer Biology, Dana-Farber Cancer Institute; 3Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston; 4Broad Institute of Harvard and MIT, Cambridge; 5MGH Cancer Center, 6Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, Massachusetts; and 7Department of Surgery, Division of Biology and Biomedical Sciences, Washington University, St. Louis, Missouri.

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April 2014

Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.

Cancer Discov 2013 Sep 13;3(9):1044-57. Epub 2013 Jun 13.

1Departments of Medical Oncology and 2Cancer Biology; 3Center for Cancer Genome Discovery, Dana-Farber Cancer Institute;4Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston; 5Broad Institute of Harvard and MIT, Cambridge, Massachusetts; and 6Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina.

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September 2013

IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex.

Cell Rep 2013 Mar 28;3(3):724-33. Epub 2013 Feb 28.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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March 2013

IκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformation.

Mol Cell Biol 2012 Dec 24;32(23):4756-68. Epub 2012 Sep 24.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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December 2012

Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas.

Blood 2009 Mar 15;113(11):2478-87. Epub 2009 Jan 15.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095-1732, USA.

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March 2009

Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation.

Blood 2006 Sep 25;108(6):1991-8. Epub 2006 May 25.

Department of Pathology, David Geffen School of Medicine, University of California-Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095-1732, USA.

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September 2006

TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin.

Blood 2003 Jun 6;101(12):5007-9. Epub 2003 Feb 6.

Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston 77030, USA.

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June 2003

Sp1 transactivation of the TCL1 oncogene.

J Biol Chem 2003 Jan 5;278(2):948-55. Epub 2002 Nov 5.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Center for the Health Sciences, Los Angeles, California 90095-1732, USA.

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January 2003

Transdifferentiation and nuclear reprogramming in hematopoietic development and neoplasia.

Immunol Rev 2002 Sep;187:22-39

Department of Pathology and Laboratory Medicine, UCLA School of Medicine, Los Angeles, CA 90095-1732, USA.

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September 2002

A modeled hydrophobic domain on the TCL1 oncoprotein mediates association with AKT at the cytoplasmic membrane.

Biochemistry 2002 May;41(20):6376-82

Department of Pathology and Laboratory Medicine, UCLA School of Medicine, Los Angeles, California 90095-1732, USA.

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May 2002