Dr. Reza Rahimian, Pharm.D, Ph.D

Dr. Reza Rahimian

Pharm.D, Ph.D

Cayman Islands

Main Specialties: Neurology, Pharmacology

Additional Specialties: Serotonin Pharmacology

Dr. Reza Rahimian, Pharm.D, Ph.D

Dr. Reza Rahimian

Pharm.D, Ph.D
Introduction

Specialties:

Additional Specialties:

Research Interests:

Metrics

53

Publications

1206

Profile Views

276

Reads

216

PubMed Central Citations

Publications

53Publications

276Reads

216PubMed Central Citations

Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration.

Neurotherapeutics 2017 04;14(2):447-462

Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec, Québec City, G1J 2G3, Canada.

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April 2017
15 Reads
2 PubMed Central Citations(source)

Involvement of PPARγ in the protective action of tropisetron in an experimental model of ulcerative colitis.

Immunopharmacol Immunotoxicol 2016 Sep 20:1-9. Epub 2016 Sep 20.

i Cellular and Molecular Research Center and Department of Molecular Medicine , Faculty of Advanced Technologies in Medicine Iran University of Medical Sciences , Tehran , Iran.

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September 2016
11 Reads
1.11 Impact Factor

Effect of glatiramer acetate on short-term memory impairment induced by lipopolysaccharide in male mice.

Fundam Clin Pharmacol 2016 Aug 8;30(4):347-56. Epub 2016 Jun 8.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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August 2016
9 Reads
3 PubMed Central Citations(source)
2.08 Impact Factor

Oxytocin is involved in the proconvulsant effects of Sildenafil: Possible role of CREB.

Toxicol Lett 2016 Aug 21;256:44-52. Epub 2016 May 21.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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August 2016
2 Reads
3.26 Impact Factor

Enhancement of Cisplatin Nephrotoxicity by Morphine and Its Attenuation by the Opioid Antagonist Naltrexone.

Acta Med Iran 2016 Jul;54(7):422-9

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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July 2016
6 Reads

Tropisetron suppresses colitis-associated cancer in a mouse model in the remission stage.

Int Immunopharmacol 2016 Jul 19;36:9-16. Epub 2016 Apr 19.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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July 2016
7 Reads
2.47 Impact Factor

Peroxisome Proliferator-Activated Receptor-α Inhibition Protects Against Doxorubicin-Induced Cardiotoxicity in Mice.

Cardiovasc Toxicol 2016 07;16(3):244-50

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.

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July 2016
9 Reads
1 PubMed Central Citation(source)
2.06 Impact Factor

IL-10 Controls Early Microglial Phenotypes and Disease Onset in ALS Caused by Misfolded Superoxide Dismutase 1.

J Neurosci 2016 Jan;36(3):1031-48

Department of Psychiatry and Neuroscience, Faculty of Medicine, Research Centre of the Mental Health Institute of Quebec, Laval University, Quebec, Quebec G1J 2G3, Canada

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January 2016
6 Reads
7 PubMed Central Citations(source)
6.34 Impact Factor

Behavioral despair associated with a mouse model of Crohn's disease: Role of nitric oxide pathway.

Prog Neuropsychopharmacol Biol Psychiatry 2016 Jan 9;64:131-41. Epub 2015 Aug 9.

Department of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Internal Medicine section of Gastroenterology, and Inflammatory Bowel Disease Clinical & Research Center, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:

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January 2016
3 Reads
2 PubMed Central Citations(source)
3.69 Impact Factor

From Chemotherapy-Induced Emesis to Neuroprotection: Therapeutic Opportunities for 5-HT3 Receptor Antagonists.

Mol Neurobiol 2015 Dec 7;52(3):1670-1679. Epub 2014 Nov 7.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P. O. Box 13145-784, Tehran, Iran.

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December 2015
6 Reads
3 PubMed Central Citations(source)
5.14 Impact Factor

Dinitrobenzene sulphonic acid-induced colitis impairs spatial recognition memory in mice: roles of N-methyl D-aspartate receptors and nitric oxide.

Psychopharmacology (Berl) 2015 Aug 14;232(16):3081-90. Epub 2015 May 14.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145-784, Tehran, Iran.

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August 2015
3 Reads
1 PubMed Central Citation(source)
3.88 Impact Factor

Protective effects of lithium chloride on seizure susceptibility: Involvement of α2-adrenoceptor.

Pharmacol Biochem Behav 2015 Jun 27;133:37-42. Epub 2015 Mar 27.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran" to the Ahmad reza Dehpour. Electronic address:

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June 2015
6 Reads
1 PubMed Central Citation(source)
2.78 Impact Factor

Therapeutic potential of cannabinoids in counteracting chemotherapy-induced adverse effects: an exploratory review.

Phytother Res 2015 Mar 12;29(3):332-8. Epub 2014 Dec 12.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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March 2015
8 Reads
1 PubMed Central Citation(source)
2.40 Impact Factor

Involvement of PPAR receptors in the anticonvulsant effects of a cannabinoid agonist, WIN 55,212-2.

Prog Neuropsychopharmacol Biol Psychiatry 2015 Mar 13;57:140-5. Epub 2014 Nov 13.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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March 2015
5 Reads
4 PubMed Central Citations(source)
3.69 Impact Factor

Lithium protects against spinal cord injury in rats: role of nitric oxide.

J Neurol Surg A Cent Eur Neurosurg 2014 Nov 7;75(6):427-33. Epub 2013 Nov 7.

Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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November 2014
3 Reads
2 PubMed Central Citations(source)
0.49 Impact Factor

Tropisetron attenuates cisplatin-induced nephrotoxicity in mice.

Eur J Pharmacol 2014 Sep 4;738:222-9. Epub 2014 Jun 4.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145-784, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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September 2014
5 Reads
5 PubMed Central Citations(source)
2.53 Impact Factor

Protective effect of hydroalcoholic olive leaf extract on experimental model of colitis in rat: involvement of nitrergic and opioidergic systems.

Phytother Res 2014 Sep 4;28(9):1367-73. Epub 2014 Mar 4.

Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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September 2014
4 Reads
2 PubMed Central Citations(source)
2.40 Impact Factor

5-HT3 receptor antagonists: new promising therapeutic agents in diabetes and its complications.

Acta Med Iran 2013 ;51(10):736

Department of Pharmacology, School of Medicine AND Brain and Spinal Injury Repair Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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July 2014

Nitric oxide mediates the anticonvulsant effects of thalidomide on pentylenetetrazole-induced clonic seizures in mice.

Epilepsy Behav 2014 May 14;34:99-104. Epub 2014 Apr 14.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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May 2014
8 Reads
2.26 Impact Factor

The role of serotonin in memory: interactions with neurotransmitters and downstream signaling.

Exp Brain Res 2014 Mar 16;232(3):723-38. Epub 2014 Jan 16.

Department of Molecular Imaging, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.

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March 2014
1 Read
14 PubMed Central Citations(source)
2.04 Impact Factor

Antinociceptive and antidiarrheal effects of pioglitazone in a rat model of diarrhoea-predominant irritable bowel syndrome: role of nitric oxide.

Clin Exp Pharmacol Physiol 2014 Feb;41(2):118-26

Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, Tehran University of Medical Sciences, Tehran, Iran.

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February 2014
6 Reads
5 PubMed Central Citations(source)

The role of different serotonin receptor subtypes in seizure susceptibility.

Exp Brain Res 2014 Feb 14;232(2):347-67. Epub 2013 Nov 14.

View Article
February 2014
6 Reads
8 PubMed Central Citations(source)
2.04 Impact Factor

Tropisetron attenuates amyloid-beta-induced inflammatory and apoptotic responses in rats.

Eur J Clin Invest 2013 Oct 13;43(10):1039-51. Epub 2013 Aug 13.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Brain and Spinal Injury Repair Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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October 2013
2 Reads
4 PubMed Central Citations(source)
2.73 Impact Factor

Tropisetron diminishes demyelination and disease severity in an animal model of multiple sclerosis.

Neuroscience 2013 Sep 15;248:299-306. Epub 2013 Jun 15.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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September 2013
6 Reads
2 PubMed Central Citations(source)
3.36 Impact Factor

Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors.

J Med Chem 2013 Aug 31;56(16):6279-96. Epub 2013 May 31.

Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale "A. Avogadro", Largo Donegani 2, 28100 Novara, Italy.

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August 2013
6 Reads
27 PubMed Central Citations(source)
5.45 Impact Factor

Role of nitric oxide in additive anticonvulsant effects of agmatine and morphine.

Physiol Behav 2013 Jun 14;118:52-7. Epub 2013 May 14.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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June 2013
5 Reads
1 PubMed Central Citation(source)
2.98 Impact Factor

Estradiol reduces depressive-like behavior through inhibiting nitric oxide/cyclic GMP pathway in ovariectomized mice.

Horm Behav 2013 Feb 19;63(2):361-9. Epub 2012 Dec 19.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.

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February 2013
5 Reads
4 PubMed Central Citations(source)
4.63 Impact Factor

5-HT(3) receptor mediates the dose-dependent effects of citalopram on pentylenetetrazole-induced clonic seizure in mice: involvement of nitric oxide.

Epilepsy Res 2012 Sep 9;101(3):217-27. Epub 2012 May 9.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

View Article
September 2012
11 Reads
5 PubMed Central Citations(source)
2.02 Impact Factor

WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway.

Neuropharmacology 2012 Sep 23;63(4):653-66. Epub 2012 May 23.

Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, P.O. Box: 19615-1178, Tehran, Iran.

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September 2012
11 Reads
19 PubMed Central Citations(source)
5.11 Impact Factor

Impact of 5-HT₃ receptor antagonists on peripheral and central diseases.

Drug Discov Today 2012 Jul 25;17(13-14):741-7. Epub 2012 Feb 25.

Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

View Article
July 2012
3 Reads
6 PubMed Central Citations(source)
6.69 Impact Factor

The NAMPT inhibitor FK866 reverts the damage in spinal cord injury.

J Neuroinflammation 2012 Apr 10;9:66. Epub 2012 Apr 10.

Department of Clinical and Experimental Medicine and Pharmacology, School of Medicine, University of Messina, Torre Biologica-Policlinico Universitario Via C, Valeria Gazzi, 98100 Messina, Italy.

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April 2012
11 Reads
11 PubMed Central Citations(source)
5.41 Impact Factor

Sildenafil attenuates TNBS-induced colitis in rats: possible involvement of cGMP and KATP channels.

Fundam Clin Pharmacol 2012 Apr;26(2):190-3

Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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April 2012
1 Read
2 PubMed Central Citations(source)
2.08 Impact Factor

Ser/ Thr residues at α3/β5 loop of Gαs are important in morphine-induced adenylyl cyclase sensitization but not mitogen-activated protein kinase phosphorylation.

FEBS J 2012 Feb 13;279(4):650-60. Epub 2012 Jan 13.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran.

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February 2012
7 Reads
1 PubMed Central Citation(source)
4.00 Impact Factor

Tropisetron upregulates cannabinoid CB1 receptors in cerebellar granule cells: possible involvement of calcineurin.

Brain Res 2011 Oct 27;1417:1-8. Epub 2011 Aug 27.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

View Article
October 2011
3 Reads
2 PubMed Central Citations(source)
2.84 Impact Factor

Additive anticonvulsant effects of agmatine and lithium chloride on pentylenetetrazole-induced clonic seizure in mice: involvement of α₂-adrenoceptor.

Eur J Pharmacol 2011 Sep 1;666(1-3):93-9. Epub 2011 Jun 1.

Tehran University of Medical Sciences, School of Medicine, Department of Pharmacology, Iran.

View Article
September 2011
3 Reads
1 PubMed Central Citation(source)
2.53 Impact Factor

Tropisetron ameliorates ischemic brain injury in an embolic model of stroke.

Brain Res 2011 May 27;1392:101-9. Epub 2011 Mar 27.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.

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May 2011
3 Reads
3 PubMed Central Citations(source)
2.84 Impact Factor

Tricyclic antidepressants intoxication in Tehran, Iran: epidemiology and associated factors.

Hum Exp Toxicol 2011 Apr 20;30(4):283-8. Epub 2010 May 20.

Sina Trauma and Surgery Research Center, Sina Hospital, Tehrarn University of Medical Sciences, Tehran, Iran.

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April 2011
2 Reads
8 PubMed Central Citations(source)
1.41 Impact Factor

Suppression of nitric oxide synthesis by L-NAME reverses the beneficial effects of pioglitazone on scopolamine-induced memory impairment in mice.

Eur J Pharmacol 2011 Jan 14;650(1):240-8. Epub 2010 Oct 14.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

View Article
January 2011
5 Reads
7 PubMed Central Citations(source)
2.53 Impact Factor

Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats.

Eur J Pharmacol 2010 Dec 22;649(1-3):376-81. Epub 2010 Sep 22.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

View Article
December 2010
8 Reads
14 PubMed Central Citations(source)
2.53 Impact Factor

Agmatine enhances the anticonvulsant effect of lithium chloride on pentylenetetrazole-induced seizures in mice: Involvement of L-arginine/nitric oxide pathway.

Epilepsy Behav 2010 Jul 20;18(3):186-92. Epub 2010 May 20.

Department of Pharmacology, School of Medicine, Medical Sciences/University of Tehran, Tehran, Iran.

View Article
July 2010
4 Reads
3 PubMed Central Citations(source)
2.26 Impact Factor

Involvement of nitric oxide-cGMP pathway in the anticonvulsant effects of lithium chloride on PTZ-induced seizure in mice.

Epilepsy Res 2010 May 20;89(2-3):295-302. Epub 2010 Mar 20.

Department of Pharmacology, School of Medicine, Medical Sciences/University of Tehran, P.O. Box 13145-784, Tehran, Iran.

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May 2010
2 Reads
2 PubMed Central Citations(source)
2.02 Impact Factor

Granisetron ameliorates acetic acid-induced colitis in rats.

Hum Exp Toxicol 2010 Apr 12;29(4):321-8. Epub 2010 Feb 12.

Department of Pharmacology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

View Article
April 2010
4 Reads
6 PubMed Central Citations(source)
1.41 Impact Factor

Effect of pioglitazone on sciatic nerve ischemia/reperfusion injury in rats.

Pediatr Neurosurg 2009 21;45(2):126-31. Epub 2009 Mar 21.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

View Article
February 2010
2 Reads
2 PubMed Central Citations(source)
0.50 Impact Factor

Protective effects of lithium on acetic acid-induced colitis in rats.

Dig Dis Sci 2009 Sep 10;54(9):1901-7. Epub 2008 Dec 10.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

View Article
September 2009
4 Reads
4 PubMed Central Citations(source)
2.55 Impact Factor

Protective effects of immunophilin ligands on testicular torsion/detorsion damage in rats.

Int Urol Nephrol 2009 3;41(1):93-9. Epub 2008 Sep 3.

Basic Medical Sciences Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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August 2009
2 Reads
2 PubMed Central Citations(source)
1.29 Impact Factor

Lithium improves regeneration after sciatic nerve traumatic injury in rat.

J Reconstr Microsurg 2009 Feb 26;25(2):151. Epub 2008 Nov 26.

View Article
February 2009
9 Reads
2 PubMed Central Citations(source)
1.01 Impact Factor

A modified model for rat sciatic nerve ischemia/reperfusion injury.

Plast Reconstr Surg 2009 Jan;123(1):42e-44e

School of Medicine, Tehran University, Tehran, Iran.

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January 2009
2.99 Impact Factor

Ipsilateral common iliac artery plus femoral artery clamping for inducing sciatic nerve ischemia/reperfusion injury in rats: a reliable and simple method.

J Brachial Plex Peripher Nerve Inj 2008 Dec 22;3:27. Epub 2008 Dec 22.

Department of pharmacology, Tehran University of Medical Sciences, Tehran, Iran.

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December 2008
8 Reads
2 PubMed Central Citations(source)

Morphine is protective against doxorubicin-induced cardiotoxicity in rat.

Toxicology 2008 Jan 29;243(1-2):96-104. Epub 2007 Sep 29.

Department of Pharmacology, Faculty of Medicine, Medical Sciences/University of Tehran, Tehran, Iran.

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January 2008
3 Reads
7 PubMed Central Citations(source)
3.62 Impact Factor