Dr. Reza Rahimian, Pharm.D, Ph.D

Dr. Reza Rahimian

Pharm.D, Ph.D

Cayman Islands

Main Specialties: Neurology, Pharmacology

Additional Specialties: Serotonin Pharmacology

Dr. Reza Rahimian, Pharm.D, Ph.D

Dr. Reza Rahimian

Pharm.D, Ph.D

Introduction

Specialties:

Additional Specialties:

Research Interests:

Publications

53Publications

484Reads

1310Profile Views

221PubMed Central Citations

Involvement of PPARγ in the protective action of tropisetron in an experimental model of ulcerative colitis.

Immunopharmacol Immunotoxicol 2016 Sep 20:1-9. Epub 2016 Sep 20.

i Cellular and Molecular Research Center and Department of Molecular Medicine , Faculty of Advanced Technologies in Medicine Iran University of Medical Sciences , Tehran , Iran.

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http://dx.doi.org/10.1080/08923973.2016.1231202DOI Listing
September 2016
24 Reads
1.110 Impact Factor

Oxytocin is involved in the proconvulsant effects of Sildenafil: Possible role of CREB.

Toxicol Lett 2016 Aug 21;256:44-52. Epub 2016 May 21.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2016.05.018DOI Listing
August 2016
5 Reads
3.262 Impact Factor

Effect of glatiramer acetate on short-term memory impairment induced by lipopolysaccharide in male mice.

Fundam Clin Pharmacol 2016 Aug 8;30(4):347-56. Epub 2016 Jun 8.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1111/fcp.12202DOI Listing
August 2016
17 Reads
3 Citations
2.080 Impact Factor

Enhancement of Cisplatin Nephrotoxicity by Morphine and Its Attenuation by the Opioid Antagonist Naltrexone.

Acta Med Iran 2016 Jul;54(7):422-9

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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July 2016
20 Reads

Tropisetron suppresses colitis-associated cancer in a mouse model in the remission stage.

Int Immunopharmacol 2016 Jul 19;36:9-16. Epub 2016 Apr 19.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2016.04.014DOI Listing
July 2016
14 Reads
2.472 Impact Factor

Peroxisome Proliferator-Activated Receptor-α Inhibition Protects Against Doxorubicin-Induced Cardiotoxicity in Mice.

Cardiovasc Toxicol 2016 07;16(3):244-50

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.

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http://dx.doi.org/10.1007/s12012-015-9332-0DOI Listing
July 2016
19 Reads
1 Citation
2.060 Impact Factor

IL-10 Controls Early Microglial Phenotypes and Disease Onset in ALS Caused by Misfolded Superoxide Dismutase 1.

J Neurosci 2016 Jan;36(3):1031-48

Department of Psychiatry and Neuroscience, Faculty of Medicine, Research Centre of the Mental Health Institute of Quebec, Laval University, Quebec, Quebec G1J 2G3, Canada

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http://dx.doi.org/10.1523/JNEUROSCI.0854-15.2016DOI Listing
January 2016
23 Reads
7 Citations
6.344 Impact Factor

Behavioral despair associated with a mouse model of Crohn's disease: Role of nitric oxide pathway.

Prog Neuropsychopharmacol Biol Psychiatry 2016 Jan 9;64:131-41. Epub 2015 Aug 9.

Department of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Internal Medicine section of Gastroenterology, and Inflammatory Bowel Disease Clinical & Research Center, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2015.08.004DOI Listing
January 2016
9 Reads
2 Citations
3.690 Impact Factor

From Chemotherapy-Induced Emesis to Neuroprotection: Therapeutic Opportunities for 5-HT3 Receptor Antagonists.

Mol Neurobiol 2015 Dec 7;52(3):1670-1679. Epub 2014 Nov 7.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P. O. Box 13145-784, Tehran, Iran.

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http://dx.doi.org/10.1007/s12035-014-8957-5DOI Listing
December 2015
6 Reads
3 Citations
5.140 Impact Factor

Dinitrobenzene sulphonic acid-induced colitis impairs spatial recognition memory in mice: roles of N-methyl D-aspartate receptors and nitric oxide.

Psychopharmacology (Berl) 2015 Aug 14;232(16):3081-90. Epub 2015 May 14.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145-784, Tehran, Iran.

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http://link.springer.com/content/pdf/10.1007/s00213-015-3950
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http://link.springer.com/10.1007/s00213-015-3950-x
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http://dx.doi.org/10.1007/s00213-015-3950-xDOI Listing
August 2015
8 Reads
1 Citation
3.880 Impact Factor

Protective effects of lithium chloride on seizure susceptibility: Involvement of α2-adrenoceptor.

Pharmacol Biochem Behav 2015 Jun 27;133:37-42. Epub 2015 Mar 27.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran" to the Ahmad reza Dehpour. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2015.03.016DOI Listing
June 2015
16 Reads
1 Citation
2.781 Impact Factor

Therapeutic potential of cannabinoids in counteracting chemotherapy-induced adverse effects: an exploratory review.

Phytother Res 2015 Mar 12;29(3):332-8. Epub 2014 Dec 12.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1002/ptr.5265DOI Listing
March 2015
10 Reads
1 Citation
2.400 Impact Factor

Involvement of PPAR receptors in the anticonvulsant effects of a cannabinoid agonist, WIN 55,212-2.

Prog Neuropsychopharmacol Biol Psychiatry 2015 Mar 13;57:140-5. Epub 2014 Nov 13.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1016/j.pnpbp.2014.11.005DOI Listing
March 2015
7 Reads
4 Citations
3.690 Impact Factor

Lithium protects against spinal cord injury in rats: role of nitric oxide.

J Neurol Surg A Cent Eur Neurosurg 2014 Nov 7;75(6):427-33. Epub 2013 Nov 7.

Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0033-1345098
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http://dx.doi.org/10.1055/s-0033-1345098DOI Listing
November 2014
4 Reads
2 Citations
0.493 Impact Factor

Protective effect of hydroalcoholic olive leaf extract on experimental model of colitis in rat: involvement of nitrergic and opioidergic systems.

Phytother Res 2014 Sep 4;28(9):1367-73. Epub 2014 Mar 4.

Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1002/ptr.5139DOI Listing
September 2014
6 Reads
2 Citations
2.400 Impact Factor

Tropisetron attenuates cisplatin-induced nephrotoxicity in mice.

Eur J Pharmacol 2014 Sep 4;738:222-9. Epub 2014 Jun 4.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145-784, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00142999140041
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http://dx.doi.org/10.1016/j.ejphar.2014.05.050DOI Listing
September 2014
8 Reads
7 Citations
2.532 Impact Factor

5-HT3 receptor antagonists: new promising therapeutic agents in diabetes and its complications.

Acta Med Iran 2013 ;51(10):736

Department of Pharmacology, School of Medicine AND Brain and Spinal Injury Repair Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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July 2014
1 Read

Nitric oxide mediates the anticonvulsant effects of thalidomide on pentylenetetrazole-induced clonic seizures in mice.

Epilepsy Behav 2014 May 14;34:99-104. Epub 2014 Apr 14.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15255050140010
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http://dx.doi.org/10.1016/j.yebeh.2014.03.020DOI Listing
May 2014
12 Reads
2.260 Impact Factor

The role of serotonin in memory: interactions with neurotransmitters and downstream signaling.

Exp Brain Res 2014 Mar 16;232(3):723-38. Epub 2014 Jan 16.

Department of Molecular Imaging, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.

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http://link.springer.com/content/pdf/10.1007/s00221-013-3818
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http://link.springer.com/10.1007/s00221-013-3818-4
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http://dx.doi.org/10.1007/s00221-013-3818-4DOI Listing
March 2014
1 Read
15 Citations
2.040 Impact Factor

Antinociceptive and antidiarrheal effects of pioglitazone in a rat model of diarrhoea-predominant irritable bowel syndrome: role of nitric oxide.

Clin Exp Pharmacol Physiol 2014 Feb;41(2):118-26

Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, Tehran University of Medical Sciences, Tehran, Iran.

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http://doi.wiley.com/10.1111/1440-1681.12188
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http://dx.doi.org/10.1111/1440-1681.12188DOI Listing
February 2014
10 Reads
5 Citations

The role of different serotonin receptor subtypes in seizure susceptibility.

Exp Brain Res 2014 Feb 14;232(2):347-67. Epub 2013 Nov 14.

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http://link.springer.com/10.1007/s00221-013-3757-0
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http://dx.doi.org/10.1007/s00221-013-3757-0DOI Listing
February 2014
9 Reads
8 Citations
2.040 Impact Factor

Tropisetron attenuates amyloid-beta-induced inflammatory and apoptotic responses in rats.

Eur J Clin Invest 2013 Oct 13;43(10):1039-51. Epub 2013 Aug 13.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Brain and Spinal Injury Repair Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1111/eci.12141DOI Listing
October 2013
2 Reads
4 Citations
2.734 Impact Factor

Tropisetron diminishes demyelination and disease severity in an animal model of multiple sclerosis.

Neuroscience 2013 Sep 15;248:299-306. Epub 2013 Jun 15.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2013.06.009DOI Listing
September 2013
9 Reads
2 Citations
3.360 Impact Factor

Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors.

J Med Chem 2013 Aug 31;56(16):6279-96. Epub 2013 May 31.

Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale "A. Avogadro", Largo Donegani 2, 28100 Novara, Italy.

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http://dx.doi.org/10.1021/jm4001049DOI Listing
August 2013
7 Reads
27 Citations
5.450 Impact Factor

Role of nitric oxide in additive anticonvulsant effects of agmatine and morphine.

Physiol Behav 2013 Jun 14;118:52-7. Epub 2013 May 14.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1016/j.physbeh.2013.05.022DOI Listing
June 2013
11 Reads
1 Citation
2.980 Impact Factor

Estradiol reduces depressive-like behavior through inhibiting nitric oxide/cyclic GMP pathway in ovariectomized mice.

Horm Behav 2013 Feb 19;63(2):361-9. Epub 2012 Dec 19.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.

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http://dx.doi.org/10.1016/j.yhbeh.2012.12.005DOI Listing
February 2013
6 Reads
4 Citations
4.632 Impact Factor

WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway.

Neuropharmacology 2012 Sep 23;63(4):653-66. Epub 2012 May 23.

Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, P.O. Box: 19615-1178, Tehran, Iran.

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http://dx.doi.org/10.1016/j.neuropharm.2012.05.013DOI Listing
September 2012
20 Reads
20 Citations
5.110 Impact Factor

5-HT(3) receptor mediates the dose-dependent effects of citalopram on pentylenetetrazole-induced clonic seizure in mice: involvement of nitric oxide.

Epilepsy Res 2012 Sep 9;101(3):217-27. Epub 2012 May 9.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1016/j.eplepsyres.2012.04.004DOI Listing
September 2012
17 Reads
5 Citations
2.020 Impact Factor

How can 5-HT(3) receptor antagonists exert analgesic properties?

Acta Med Iran 2012 ;50(4):225

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September 2012
4 Reads

Impact of 5-HT₃ receptor antagonists on peripheral and central diseases.

Drug Discov Today 2012 Jul 25;17(13-14):741-7. Epub 2012 Feb 25.

Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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https://linkinghub.elsevier.com/retrieve/pii/S13596446120006
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http://dx.doi.org/10.1016/j.drudis.2012.02.009DOI Listing
July 2012
4 Reads
6 Citations
6.691 Impact Factor

The NAMPT inhibitor FK866 reverts the damage in spinal cord injury.

J Neuroinflammation 2012 Apr 10;9:66. Epub 2012 Apr 10.

Department of Clinical and Experimental Medicine and Pharmacology, School of Medicine, University of Messina, Torre Biologica-Policlinico Universitario Via C, Valeria Gazzi, 98100 Messina, Italy.

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http://dx.doi.org/10.1186/1742-2094-9-66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353188PMC
April 2012
18 Reads
11 Citations
5.410 Impact Factor

Sildenafil attenuates TNBS-induced colitis in rats: possible involvement of cGMP and KATP channels.

Fundam Clin Pharmacol 2012 Apr;26(2):190-3

Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1111/j.1472-8206.2011.00928.xDOI Listing
April 2012
1 Read
2 Citations
2.080 Impact Factor

Tropisetron upregulates cannabinoid CB1 receptors in cerebellar granule cells: possible involvement of calcineurin.

Brain Res 2011 Oct 27;1417:1-8. Epub 2011 Aug 27.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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https://linkinghub.elsevier.com/retrieve/pii/S00068993110157
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http://dx.doi.org/10.1016/j.brainres.2011.08.050DOI Listing
October 2011
4 Reads
2 Citations
2.843 Impact Factor

Additive anticonvulsant effects of agmatine and lithium chloride on pentylenetetrazole-induced clonic seizure in mice: involvement of α₂-adrenoceptor.

Eur J Pharmacol 2011 Sep 1;666(1-3):93-9. Epub 2011 Jun 1.

Tehran University of Medical Sciences, School of Medicine, Department of Pharmacology, Iran.

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http://dx.doi.org/10.1016/j.ejphar.2011.05.043DOI Listing
September 2011
9 Reads
1 Citation
2.532 Impact Factor

Tropisetron ameliorates ischemic brain injury in an embolic model of stroke.

Brain Res 2011 May 27;1392:101-9. Epub 2011 Mar 27.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.

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http://dx.doi.org/10.1016/j.brainres.2011.03.053DOI Listing
May 2011
3 Reads
3 Citations
2.843 Impact Factor

Tricyclic antidepressants intoxication in Tehran, Iran: epidemiology and associated factors.

Hum Exp Toxicol 2011 Apr 20;30(4):283-8. Epub 2010 May 20.

Sina Trauma and Surgery Research Center, Sina Hospital, Tehrarn University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1177/0960327110371701DOI Listing
April 2011
3 Reads
8 Citations
1.410 Impact Factor

Suppression of nitric oxide synthesis by L-NAME reverses the beneficial effects of pioglitazone on scopolamine-induced memory impairment in mice.

Eur J Pharmacol 2011 Jan 14;650(1):240-8. Epub 2010 Oct 14.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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https://linkinghub.elsevier.com/retrieve/pii/S00142999100101
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http://dx.doi.org/10.1016/j.ejphar.2010.10.007DOI Listing
January 2011
8 Reads
7 Citations
2.532 Impact Factor

Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats.

Eur J Pharmacol 2010 Dec 22;649(1-3):376-81. Epub 2010 Sep 22.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1016/j.ejphar.2010.09.044DOI Listing
December 2010
10 Reads
14 Citations
2.532 Impact Factor

Agmatine enhances the anticonvulsant effect of lithium chloride on pentylenetetrazole-induced seizures in mice: Involvement of L-arginine/nitric oxide pathway.

Epilepsy Behav 2010 Jul 20;18(3):186-92. Epub 2010 May 20.

Department of Pharmacology, School of Medicine, Medical Sciences/University of Tehran, Tehran, Iran.

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http://dx.doi.org/10.1016/j.yebeh.2010.04.014DOI Listing
July 2010
9 Reads
3 Citations
2.260 Impact Factor

Involvement of nitric oxide-cGMP pathway in the anticonvulsant effects of lithium chloride on PTZ-induced seizure in mice.

Epilepsy Res 2010 May 20;89(2-3):295-302. Epub 2010 Mar 20.

Department of Pharmacology, School of Medicine, Medical Sciences/University of Tehran, P.O. Box 13145-784, Tehran, Iran.

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https://linkinghub.elsevier.com/retrieve/pii/S09201211100003
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http://dx.doi.org/10.1016/j.eplepsyres.2010.02.001DOI Listing
May 2010
4 Reads
2 Citations
2.020 Impact Factor

Granisetron ameliorates acetic acid-induced colitis in rats.

Hum Exp Toxicol 2010 Apr 12;29(4):321-8. Epub 2010 Feb 12.

Department of Pharmacology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1177/0960327110362702DOI Listing
April 2010
4 Reads
6 Citations
1.410 Impact Factor

Effect of pioglitazone on sciatic nerve ischemia/reperfusion injury in rats.

Pediatr Neurosurg 2009 21;45(2):126-31. Epub 2009 Mar 21.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1159/000209287DOI Listing
February 2010
2 Reads
2 Citations
0.500 Impact Factor

Protective effects of lithium on acetic acid-induced colitis in rats.

Dig Dis Sci 2009 Sep 10;54(9):1901-7. Epub 2008 Dec 10.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1007/s10620-008-0569-3DOI Listing
September 2009
7 Reads
4 Citations
2.550 Impact Factor

Protective effects of immunophilin ligands on testicular torsion/detorsion damage in rats.

Int Urol Nephrol 2009 3;41(1):93-9. Epub 2008 Sep 3.

Basic Medical Sciences Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1007/s11255-008-9453-5DOI Listing
August 2009
5 Reads
2 Citations
1.293 Impact Factor

Lithium improves regeneration after sciatic nerve traumatic injury in rat.

J Reconstr Microsurg 2009 Feb 26;25(2):151. Epub 2008 Nov 26.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0028-1103504
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http://dx.doi.org/10.1055/s-0028-1103504DOI Listing
February 2009
25 Reads
2 Citations
1.010 Impact Factor

A modified model for rat sciatic nerve ischemia/reperfusion injury.

Plast Reconstr Surg 2009 Jan;123(1):42e-44e

School of Medicine, Tehran University, Tehran, Iran.

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http://dx.doi.org/10.1097/PRS.0b013e318190568cDOI Listing
January 2009
1 Read
2.993 Impact Factor

Morphine is protective against doxorubicin-induced cardiotoxicity in rat.

Toxicology 2008 Jan 29;243(1-2):96-104. Epub 2007 Sep 29.

Department of Pharmacology, Faculty of Medicine, Medical Sciences/University of Tehran, Tehran, Iran.

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http://dx.doi.org/10.1016/j.tox.2007.09.026DOI Listing
January 2008
3 Reads
7 Citations
3.621 Impact Factor

Top co-authors

Ahmad Reza Dehpour
Ahmad Reza Dehpour

Tehran University of Medical Sciences

36
Gohar Fakhfouri
Gohar Fakhfouri

Tehran University of Medical Sciences

21
Shahram Ejtemaei Mehr
Shahram Ejtemaei Mehr

School of Medicine

14
Arash Bahremand
Arash Bahremand

School of Medicine

10
Borna Payandemehr
Borna Payandemehr

Tehran University of Medical Sciences

10
Kazem Mousavizadeh
Kazem Mousavizadeh

School of Medicine

8
Mohammad R Rasouli
Mohammad R Rasouli

Tehran University of Medical Sciences

6
Jean-Eric Ghia
Jean-Eric Ghia

McMaster University

6
Ali DanEshmand
Ali DanEshmand

Harvard Medical School

5
Seyed Mohammad Tavangar
Seyed Mohammad Tavangar

Tehran University of Medical Sciences

5