Reynold A Panettieri

Rutgers Institute for Translational Medicine and Science; Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.

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December 2020

An inherent dysfunction in soluble guanylyl cyclase is present in the airway of severe asthmatics and is associated with aberrant redox enzyme expression and compromised NO-cGMP signaling.

Authors:

Arnab Ghosh Cynthia J Koziol-White William F Jester Serpil C Erzurum Kewal Asosingh Reynold A Panettieri Dennis J Stuehr

Redox Biol 2021 Feb 13;39:101832. Epub 2020 Dec 13.

Department of Inflammation and Immunity, Lerner Research Institute, The Cleveland Clinic, Cleveland, OH, 44195, USA. Electronic address:

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February 2021

Clinical Outcomes and Health-Care Resource Use Associated With Reslizumab Treatment in Adults With Severe Eosinophilic Asthma in Real-World Practice.

Authors:

Michael E Wechsler Stephen P Peters Tanisha D Hill Rinat Ariely Michael R DePietro Maurice T Driessen Emi L Terasawa Darren R Thomason Reynold A Panettieri

Chest 2020 Dec 14. Epub 2020 Dec 14.

Rutgers University, New Brunswick, NJ.

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December 2020

FFAR1 activation attenuates histamine-induced myosin light chain phosphorylation and cortical tension development in human airway smooth muscle cells.

Authors:

Shengjie Xu Anthony Schwab Nikhil Karmacharya Gaoyuan Cao Joanna Woo Nicholas Kim Steven S An Reynold A Panettieri Joseph A Jude

Respir Res 2020 Nov 30;21(1):317. Epub 2020 Nov 30.

The Joint Graduate Program in Toxicology, Department of Pharmacology & Toxicology, Ernest Mario School of Pharmacy, Piscataway, USA.

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November 2020

Airway relaxation mechanisms and structural basis of osthole for improving lung function in asthma.

Authors:

Sheng Wang Yan Xie Yan-Wu Huo Yan Li Peter W Abel Haihong Jiang Xiaohan Zou Hai-Zhan Jiao Xiaolin Kuang Dennis W Wolff You-Guo Huang Thomas B Casale Reynold A Panettieri Taotao Wei Zhengyu Cao Yaping Tu

Sci Signal 2020 11 24;13(659). Epub 2020 Nov 24.

Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.

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November 2020

Prevalence of SARS-CoV-2 infection in previously undiagnosed health care workers in New Jersey, at the onset of the U.S. COVID-19 pandemic.

Authors:

Emily S Barrett Daniel B Horton Jason Roy Maria Laura Gennaro Andrew Brooks Jay Tischfield Patricia Greenberg Tracy Andrews Sugeet Jagpal Nancy Reilly Jeffrey L Carson Martin J Blaser Reynold A Panettieri

BMC Infect Dis 2020 Nov 16;20(1):853. Epub 2020 Nov 16.

Department of Medicine, Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, New Jersey, 08901, USA.

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November 2020

The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.

Authors:

Jessie Huang Hong Lam Cynthia Koziol-White Nathachit Limjunyawong Donghwa Kim Nicholas Kim Nikhil Karmacharya Premraj Rajkumar Danielle Firer Nicholas M Dalesio Joseph Jude Richard C Kurten Jennifer L Pluznick Deepak A Deshpande Raymond B Penn Stephen B Liggett Reynold A Panettieri Xinzhong Dong Steven S An

Proc Natl Acad Sci U S A 2020 11 23;117(45):28485-28495. Epub 2020 Oct 23.

Department of Pharmacology, Rutgers-Robert Wood Johnson Medical School, The State University of New Jersey, Piscataway, NJ 08854;

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November 2020

Dexamethasone rescues TGF-β1-mediated β-adrenergic receptor dysfunction and attenuates phosphodiesterase 4D expression in human airway smooth muscle cells.

Authors:

Elena Chung Christie A Ojiaku Gaoyuan Cao Vishal Parikh Brian Deeney Shengjie Xu Serena Wang Reynold A Panettieri Cynthia Koziol-White

Respir Res 2020 Oct 8;21(1):256. Epub 2020 Oct 8.

Rutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.

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October 2020

The CHRONICLE Study of US Adults with Subspecialist-Treated Severe Asthma: Objectives, Design, and Initial Results.

Authors:

Christopher S Ambrose Bradley E Chipps Wendy C Moore Weily Soong Jennifer Trevor Dennis K Ledford Warner W Carr Njira Lugogo Frank Trudo Trung N Tran Reynold A Panettieri

Pragmat Obs Res 2020 16;11:77-90. Epub 2020 Jul 16.

Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.

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July 2020

ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020.

Authors:

Elliott Lilley S Clare Stanford David E Kendall Stephen P H Alexander Giuseppe Cirino James R Docherty Christopher H George Paul A Insel Angelo A Izzo Yong Ji Reynold A Panettieri Christopher G Sobey Barbara Stefanska Gary Stephens Mauro Teixeira Amrita Ahluwalia

Br J Pharmacol 2020 Aug 14;177(16):3611-3616. Epub 2020 Jul 14.

William Harvey Research Institute, Queen Mary University of London, London, UK.

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August 2020

TENOR Revisited.

Authors:

Reynold A Panettieri Geoffrey Chupp

J Allergy Clin Immunol Pract 2020 Jul - Aug;8(7):2254-2255

Yale Center for Asthma and Airways Disease, Yale University, New Haven, CT.

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April 2020

Asthma and COVID: What Are the Important Questions?

Authors:

Reynold A Panettieri Jeffrey Carson Daniel Horton Emily Barrett Jason Roy Jared Radbel

J Allergy Clin Immunol Pract 2020 Sep 22;8(8):2487-2488. Epub 2020 Jun 22.

Rutgers Robert Wood Johnson Medical School, Rutgers Biomedical and Health Sciences, New Brunswick, NJ.

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September 2020

Prevalence of SARS-CoV-2 infection in previously undiagnosed health care workers at the onset of the U.S. COVID-19 epidemic.

Authors:

Emily S Barrett Daniel B Horton Jason Roy Maria Laura Gennaro Andrew Brooks Jay Tischfield Patricia Greenberg Tracy Andrews Sugeet Jagpal Nancy Reilly Martin J Blaser Jeffrey L Carson Reynold A Panettieri

medRxiv 2020 Apr 24. Epub 2020 Apr 24.

Department of Medicine, Rutgers Robert Wood Johnson Medical School; New Brunswick, NJ.

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April 2020

CD2 Regulates Pathogenesis of Asthma Induced by House Dust Mice Extract.

Authors:

Tanwir Hashem Ananth K Kammala Kanedra Thaxton Ryan M Griffin Kellie Mullany Reynold A Panettieri Hariharan Subramanian Rupali Das

Front Immunol 2020 12;11:881. Epub 2020 May 12.

College of Human Medicine, Michigan State University, East Lansing, MI, United States.

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May 2020

Important lessons learned from studies on the pharmacology of glucocorticoids in human airway smooth muscle cells: Too much of a good thing may be a problem.

Authors:

Yassine Amrani Reynold A Panettieri Patricia Ramos-Ramirez Dedmer Schaafsma Klaudia Kaczmarek Omar Tliba

Pharmacol Ther 2020 09 27;213:107589. Epub 2020 May 27.

Department of Medicine, Rutgers Institute for Translational Medicine and Science, Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Department of Biomedical Sciences, College of Veterinary Medicine, Long Island University, Brookville, NY, USA. Electronic address:

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September 2020

Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Comparable in Clinical Samples Preserved in Saline or Viral Transport Medium.

Authors:

Jared Radbel Sugeet Jagpal Jason Roy Andrew Brooks Jay Tischfield Michael Sheldon Christian Bixby Dana Witt Maria L Gennaro Daniel B Horton Emily S Barrett Jeffrey L Carson Reynold A Panettieri Martin J Blaser

J Mol Diagn 2020 07 13;22(7):871-875. Epub 2020 May 13.

Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey; Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, New Jersey. Electronic address:

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July 2020

Biologic and maintenance systemic corticosteroid therapy among US subspecialist-treated patients with severe asthma.

Authors:

Wendy C Moore Reynold A Panettieri Jennifer Trevor Dennis K Ledford Njira Lugogo Weily Soong Bradley E Chipps Warner Carr Laura Belton Hitesh Gandhi Frank Trudo Christopher S Ambrose

Ann Allergy Asthma Immunol 2020 09 15;125(3):294-303.e1. Epub 2020 Apr 15.

AstraZeneca, Gaithersburg, Maryland. Electronic address:

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September 2020

The COVID-19 pandemic and research shutdown: staying safe and productive.

Authors:

M Bishr Omary Jeetendra Eswaraka S David Kimball Prabhas V Moghe Reynold A Panettieri Kathleen W Scotto

J Clin Invest 2020 Jun;130(6):2745-2748

Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, USA.

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June 2020

RGS4 promotes allergen- and aspirin-associated airway hyperresponsiveness by inhibiting PGE2 biosynthesis.

Authors:

Gordon S Wong Jamie L Redes Nariman Balenga Morgan McCullough Nathalie Fuentes Ameya Gokhale Cynthia Koziol-White Joseph A Jude Laura A Madigan Eunice C Chan William H Jester Sabrina Biardel Nicolas Flamand Reynold A Panettieri Kirk M Druey

J Allergy Clin Immunol 2020 Nov 19;146(5):1152-1164.e13. Epub 2020 Mar 19.

Lung and Vascular Inflammation Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID)/National Institutes of Health (NIH), Bethesda, Md. Electronic address:

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November 2020