Publications by authors named "Rex Chisholm"

75Publications

Genomic Medicine Year in Review: 2019.

Am J Hum Genet 2019 12 5;105(6):1072-1075. Epub 2019 Dec 5.

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ajhg.2019.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202138PMC
December 2019

The phenotypic legacy of admixture between modern humans and Neandertals.

Science 2016 Feb;351(6274):737-41

Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA. Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA. Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA. Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1126/science.aad2149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849557PMC
February 2016

Data Safe Havens in health research and healthcare.

Bioinformatics 2015 Oct 25;31(20):3241-8. Epub 2015 Jun 25.

Public Population Project in Genomics and Society (PG), Montreal, QC H3A 0G1, Canada, Centre of Genomics and Policy, McGill University, Montreal, QC H3A 0G1, Canada.

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http://dx.doi.org/10.1093/bioinformatics/btv279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595892PMC
October 2015

dictyBase 2015: Expanding data and annotations in a new software environment.

Genesis 2015 Aug 8;53(8):523-534. Epub 2015 Jul 8.

dictyBase, Northwestern University Biomedical Informatics Center and Center for Genetic Medicine, 750 N. Lake Shore Drive, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1002/dvg.22867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545684PMC
August 2015

At the Interface between Medical Informatics and Personalized Medicine: The eMERGE Network Experience.

Authors:
Rex L Chisholm

Healthc Inform Res 2013 Jun;19(2):67-8

Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.4258/hir.2013.19.2.67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717439PMC
June 2013

One stop shop for everything Dictyostelium: dictyBase and the Dicty Stock Center in 2012.

Methods Mol Biol 2013 ;983:59-92

dictyBase and the Dicty Stock Center, Center for Genetic Medicine, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1007/978-1-62703-302-2_4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762881PMC
August 2013

DictyBase 2013: integrating multiple Dictyostelid species.

Nucleic Acids Res 2013 Jan 20;41(Database issue):D676-83. Epub 2012 Nov 20.

Biomedical Informatics Center and Center for Genetic Medicine, Northwestern Univesity, Feinberg School of Medicine, 750 North Lake Shore Drive, Chicago, IL 60611, USA.

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http://nar.oxfordjournals.org/content/early/2012/11/19/nar.g
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gks1064
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http://dx.doi.org/10.1093/nar/gks1064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531180PMC
January 2013

Spliceosomal genes in the D. discoideum genome: a comparison with those in H. sapiens, D. melanogaster, A. thaliana and S. cerevisiae.

Protein Cell 2011 May 12;2(5):395-409. Epub 2011 Jun 12.

Department of Molecular and Clinical Genetics, Royal Prince Alfred Hospital and Sydney Medical School (Central), the University of Sydney, Australia.

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http://link.springer.com/10.1007/s13238-011-1052-z
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http://dx.doi.org/10.1007/s13238-011-1052-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893067PMC
May 2011

Uncovering a role for the tail of the Dictyostelium discoideum SadA protein in cell-substrate adhesion.

Eukaryot Cell 2011 May 25;10(5):662-71. Epub 2011 Mar 25.

Integrated Graduate Program in the Life Sciences, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1128/EC.00221-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127660PMC
May 2011

dictyBase update 2011: web 2.0 functionality and the initial steps towards a genome portal for the Amoebozoa.

Nucleic Acids Res 2011 Jan 17;39(Database issue):D620-4. Epub 2010 Nov 17.

dictyBase, Northwestern University Biomedical Informatics Center and Center for Genetic Medicine, 420 E Superior St, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1093/nar/gkq1103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013695PMC
January 2011

Nonmuscle myosin IIA with a GFP fused to the N-terminus of the regulatory light chain is regulated normally.

J Muscle Res Cell Motil 2010 Sep 14;31(3):163-70. Epub 2010 Aug 14.

Laboratory of Molecular Physiology, National Heart, Lung and Blood Institute, National Institutes of Health, Building 50, Room 3523, Bethesda, MD 20892, USA.

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http://link.springer.com/10.1007/s10974-010-9220-y
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http://dx.doi.org/10.1007/s10974-010-9220-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786345PMC
September 2010

Annotating the human genome with Disease Ontology.

BMC Genomics 2009 Jul 7;10 Suppl 1:S6. Epub 2009 Jul 7.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1186/1471-2164-10-S1-S6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709267PMC
July 2009

dictyBase--a Dictyostelium bioinformatics resource update.

Nucleic Acids Res 2009 Jan 30;37(Database issue):D515-9. Epub 2008 Oct 30.

dictyBase, Northwestern University Biomedical Informatics Center and Center for Genetic Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1093/nar/gkn844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686522PMC
January 2009

An anatomy ontology to represent biological knowledge in Dictyostelium discoideum.

BMC Genomics 2008 Mar 18;9:130. Epub 2008 Mar 18.

dictyBase, Northwestern University, Center for Genetic Medicine, 676 N, St, Clair, Chicago, IL 60611, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-9-130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323390PMC
March 2008

Extraction of RNA from dictyostelium.

CSH Protoc 2008 Dec 1;2008:pdb.prot5106. Epub 2008 Dec 1.

dictyBase, Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1101/pdb.prot5106DOI Listing
December 2008

Extraction of DNA from dictyostelium.

CSH Protoc 2008 Dec 1;2008:pdb.prot5105. Epub 2008 Dec 1.

dictyBase, Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://www.cshprotocols.org/cgi/doi/10.1101/pdb.prot5105
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http://dx.doi.org/10.1101/pdb.prot5105DOI Listing
December 2008

Selection of dictyostelium transformants.

CSH Protoc 2008 Dec 1;2008:pdb.prot5104. Epub 2008 Dec 1.

dictyBase, Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://www.cshprotocols.org/cgi/doi/10.1101/pdb.prot5104
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http://dx.doi.org/10.1101/pdb.prot5104DOI Listing
December 2008

Transformation of dictyostelium with plasmid DNA by electroporation.

CSH Protoc 2008 Dec 1;2008:pdb.prot5103. Epub 2008 Dec 1.

dictyBase, Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1101/pdb.prot5103DOI Listing
December 2008

Transformation of dictyostelium with plasmid DNA by calcium phosphate precipitation.

CSH Protoc 2008 Dec 1;2008:pdb.prot5102. Epub 2008 Dec 1.

dictyBase, Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://www.cshprotocols.org/cgi/doi/10.1101/pdb.prot5102
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http://dx.doi.org/10.1101/pdb.prot5102DOI Listing
December 2008

Making permanent stocks of dictyostelium.

CSH Protoc 2008 Dec 1;2008:pdb.prot5101. Epub 2008 Dec 1.

dictyBase, Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://www.cshprotocols.org/cgi/doi/10.1101/pdb.prot5101
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http://dx.doi.org/10.1101/pdb.prot5101DOI Listing
December 2008

Multicellular development of dictyostelium.

CSH Protoc 2008 Dec 1;2008:pdb.prot5100. Epub 2008 Dec 1.

dictyBase, Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://www.cshprotocols.org/cgi/doi/10.1101/pdb.prot5100
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http://dx.doi.org/10.1101/pdb.prot5100DOI Listing
December 2008

Growth and maintenance of dictyostelium cells.

CSH Protoc 2008 Dec 1;2008:pdb.prot5099. Epub 2008 Dec 1.

dictyBase, Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://www.cshprotocols.org/cgi/doi/10.1101/pdb.prot5099
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http://dx.doi.org/10.1101/pdb.prot5099DOI Listing
December 2008

Dictyostelium discoideum: The Social Ameba.

CSH Protoc 2008 Dec 1;2008:pdb.emo109. Epub 2008 Dec 1.

dictyBase, Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1101/pdb.emo109DOI Listing
December 2008

A general purpose method for extracting RNA from Dictyostelium cells.

Nat Protoc 2007 ;2(6):1329-32

dictyBase, Center for Genetic Medicine, Northwestern University, 676 North Saint Clair Street Suite 1260, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/nprot.2007.191DOI Listing
August 2007

A reliable general purpose method for extracting genomic DNA from Dictyostelium cells.

Nat Protoc 2007 ;2(6):1325-8

dictyBase, Center for Genetic Medicine, Northwestern University, 676 North Saint Clair Street Suite 1260, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/nprot.2007.180DOI Listing
August 2007

Transformation of Dictyostelium discoideum with plasmid DNA.

Nat Protoc 2007 ;2(6):1317-24

dictyBase, Center for Genetic Medicine, Northwestern University, 676 North Saint Clair Street Suite 1260, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/nprot.2007.179DOI Listing
August 2007

Protocols for growth and development of Dictyostelium discoideum.

Nat Protoc 2007 ;2(6):1307-16

dictyBase, Center for Genetic Medicine, Northwestern University, 676 North Saint Clair Street, Suite 1260, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/nprot.2007.178DOI Listing
August 2007

Xanthusbase: adapting wikipedia principles to a model organism database.

Nucleic Acids Res 2007 Jan 7;35(Database issue):D422-6. Epub 2006 Nov 7.

Department of Biology, Syracuse University, Syracuse, NY 13244, USA.

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http://dx.doi.org/10.1093/nar/gkl881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1669732PMC
January 2007

dictyBase and the Dicty Stock Center.

Methods Mol Biol 2006 ;346:51-74

dictyBase, Center for Genetic Medicine, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1385/1-59745-144-4:51DOI Listing
October 2006

dictyBase, the model organism database for Dictyostelium discoideum.

Nucleic Acids Res 2006 Jan;34(Database issue):D423-7

dictyBase, Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1093/nar/gkj090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1347453PMC
January 2006

Insights into morphogenesis from a simple developmental system.

Nat Rev Mol Cell Biol 2004 Jul;5(7):531-41

Cell and Molecular Biology, Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, Illinois 60611, USA.

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http://www.nature.com/articles/nrm1427
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http://dx.doi.org/10.1038/nrm1427DOI Listing
July 2004

Simvastatin modulates angiotensin II signaling pathway by preventing Rac1-mediated upregulation of p27.

J Am Soc Nephrol 2004 Jul;15(7):1711-20

Division of Nephrology/Hypertension, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1097/01.asn.0000129839.91567.68DOI Listing
July 2004

dictyBase: a new Dictyostelium discoideum genome database.

Nucleic Acids Res 2004 Jan;32(Database issue):D332-3

Laboratory of Cellular and Developmental Biology (50/3351), National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-8028, USA.

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http://dx.doi.org/10.1093/nar/gkh138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC308872PMC
January 2004

SadA, a novel adhesion receptor in Dictyostelium.

J Cell Biol 2002 Dec 23;159(6):1109-19. Epub 2002 Dec 23.

Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1083/jcb.200206067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173991PMC
December 2002

Phosphorylation of the myosin regulatory light chain plays a role in motility and polarity during Dictyostelium chemotaxis.

J Cell Sci 2002 Apr;115(Pt 8):1733-47

Department of Biological Sciences, University of Iowa, Iowa City, Iowa 52242, USA.

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April 2002

Cytoplasmic dynein-associated structures move bidirectionally in vivo.

J Cell Sci 2002 Apr;115(Pt 7):1453-60

Department of Cell and Molecular Biology, Robert H. Lurie Comprehensive Cancer Center, and Center for Genetic Medicine, Northwestern University Medical School, Chicago, Illinois 60611, USA.

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April 2002

A fluorescent resonant energy transfer-based biosensor reveals transient and regional myosin light chain kinase activation in lamella and cleavage furrows.

J Cell Biol 2002 Feb 28;156(3):543-53. Epub 2002 Jan 28.

Department of Cell and Molecular Biology, R.H. Lurie Comprehensive Cancer Center and Center for Genetic Medicine, Northwestern University Medical School, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1083/jcb.200110161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173328PMC
February 2002