Renxiang Tan

Renxiang Tan

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Renxiang Tan

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Corrigendum to "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells" [Redox Biol. 17 (2018) 180-191].

Redox Biol 2020 Jan 20;28:101382. Epub 2019 Nov 20.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101382DOI Listing
January 2020

GL-V9 exerts anti-T cell malignancies effects via promoting lysosome-dependent AKT1 degradation and activating AKT1/FOXO3A/BIM axis.

Free Radic Biol Med 2019 Dec 24;145:237-249. Epub 2019 Sep 24.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.09.028DOI Listing
December 2019

Correction to: Artemisinin derivatives inactivate cancer-associated fibroblasts through suppressing TGF-β signaling in breast cancer.

J Exp Clin Cancer Res 2019 11 5;38(1):451. Epub 2019 Nov 5.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China.

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http://dx.doi.org/10.1186/s13046-019-1441-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829918PMC
November 2019

Flavonoid VI-16 protects against DSS-induced colitis by inhibiting Txnip-dependent NLRP3 inflammasome activation in macrophages via reducing oxidative stress.

Mucosal Immunol 2019 09 31;12(5):1150-1163. Epub 2019 May 31.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Basic Medicine, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, 210009, Nanjing, PR China.

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http://dx.doi.org/10.1038/s41385-019-0177-xDOI Listing
September 2019

Corrigendum: Oroxylin a Inhibits the Protection of Bone Marrow Microenvironment on CML Cells Through CXCL12/CXCR4/P-gp Signaling Pathway.

Front Oncol 2019;9:990. Epub 2019 Sep 27.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing, China.

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http://dx.doi.org/10.3389/fonc.2019.00990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777436PMC
September 2019

Comparative profiling of analog targets: a case study on resveratrol for mouse melanoma metastasis suppression.

Theranostics 2018 6;8(13):3504-3516. Epub 2018 Jun 6.

The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China.

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http://www.thno.org/v08p3504.htm
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http://dx.doi.org/10.7150/thno.24336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037041PMC
August 2019

Oroxylin A increases the sensitivity of temozolomide on glioma cells by hypoxia-inducible factor 1α/hedgehog pathway under hypoxia.

J Cell Physiol 2019 Aug 20;234(10):17392-17404. Epub 2019 Feb 20.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Tongjiaxiang, Nanjing, China.

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http://dx.doi.org/10.1002/jcp.28361DOI Listing
August 2019

Pharmacodynamic Effect of Ellagic Acid on Ameliorating Cerebral Ischemia/Reperfusion Injury.

Pharmacology 2019 30;104(5-6):320-331. Epub 2019 Aug 30.

College of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China.

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http://dx.doi.org/10.1159/000502401DOI Listing
August 2019

In Vivo Detection of Subtle Vertical Root Fracture in Endodontically Treated Teeth by Cone-beam Computed Tomography.

J Endod 2019 Jul 26;45(7):856-862. Epub 2019 Apr 26.

Department of Dentomaxillofacial Radiology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.joen.2019.03.006DOI Listing
July 2019

Divergent Total Synthesis of Chaetoglines C to F.

J Org Chem 2019 Jul 25;84(13):8766-8770. Epub 2019 Jun 25.

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology, College of Chemistry and Molecular Engineering, Synthetic and Functional Biomolecules Center, and Peking-Tsinghua Center for Life Sciences , Peking University , Beijing 100871 , China.

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http://dx.doi.org/10.1021/acs.joc.9b01076DOI Listing
July 2019

Oroxylin a Inhibits the Protection of Bone Marrow Microenvironment on CML Cells Through CXCL12/CXCR4/P-gp Signaling Pathway.

Front Oncol 2019 3;9:188. Epub 2019 Apr 3.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing, China.

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http://dx.doi.org/10.3389/fonc.2019.00188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463784PMC
April 2019

G1 phase cell cycle arrest in NSCLC in response to LZ-106, an analog of enoxacin, is orchestrated through ROS overproduction in a P53-dependent manner.

Carcinogenesis 2019 03;40(1):131-144

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Tongjiaxiang, Nanjing, China.

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http://dx.doi.org/10.1093/carcin/bgy124DOI Listing
March 2019

Cytotoxic and antibacterial polyketide-indole hybrids synthesized from indole-3-carbinol by .

Acta Pharm Sin B 2019 Mar 28;9(2):369-380. Epub 2018 Sep 28.

State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing 210046, China.

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http://dx.doi.org/10.1016/j.apsb.2018.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437554PMC
March 2019

Synthesis and bioevaluation of new tacrine-cinnamic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.

J Enzyme Inhib Med Chem 2018 Dec;33(1):290-302

d Department of Medicinal Chemistry , China Pharmaceutical University , Nanjing , China.

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http://dx.doi.org/10.1080/14756366.2017.1412314DOI Listing
December 2018

Lumichrome inhibits osteoclastogenesis and bone resorption through suppressing RANKL-induced NFAT activation and calcium signaling.

J Cell Physiol 2018 11 15;233(11):8971-8983. Epub 2018 Jun 15.

School of Biomedical Sciences, University of Western Australia, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1002/jcp.26841DOI Listing
November 2018

CARM1-mediated methylation of protein arginine methyltransferase 5 represses human γ-globin gene expression in erythroleukemia cells.

J Biol Chem 2018 11 26;293(45):17454-17463. Epub 2018 Sep 26.

From the State Key Laboratory of Pharmaceutical Biotechnology, Department of Hematology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, China-Australia Center for Translational Medicine, School of Life Sciences, Nanjing University, Nanjing 210023, China,

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http://dx.doi.org/10.1074/jbc.RA118.004028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231142PMC
November 2018

Artemisinin derivatives inactivate cancer-associated fibroblasts through suppressing TGF-β signaling in breast cancer.

J Exp Clin Cancer Res 2018 Nov 26;37(1):282. Epub 2018 Nov 26.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China.

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http://dx.doi.org/10.1186/s13046-018-0960-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258160PMC
November 2018

Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells.

Redox Biol 2018 07 18;17:180-191. Epub 2018 Apr 18.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2018.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006728PMC
July 2018

A comprehensive in vitro and in vivo metabolism study of hydroxysafflor yellow A.

J Mass Spectrom 2018 Feb;53(2):99-108

State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.

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http://dx.doi.org/10.1002/jms.4041DOI Listing
February 2018

Modulating calcium-mediated NFATc1 and mitogen-activated protein kinase deactivation underlies the inhibitory effects of kavain on osteoclastogenesis and bone resorption.

J Cell Physiol 2018 01 4;234(1):789-801. Epub 2018 Aug 4.

School of Biomedical Sciences, The University of Western Australia, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1002/jcp.26893DOI Listing
January 2018

Small molecule-mediated upregulation of CCR7 ameliorates murine experimental autoimmune encephalomyelitis by accelerating T-cell homing.

Int Immunopharmacol 2017 Dec 12;53:33-41. Epub 2017 Oct 12.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2017.10.004DOI Listing
December 2017

Diptoindonesin G promotes ERK-mediated nuclear translocation of p-STAT1 (Ser727) and cell differentiation in AML cells.

Cell Death Dis 2017 05 4;8(5):e2765. Epub 2017 May 4.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China.

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http://dx.doi.org/10.1038/cddis.2017.159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520695PMC
May 2017

Heterochromatin Protein 1γ Is a Novel Epigenetic Repressor of Human Embryonic ϵ-Globin Gene Expression.

J Biol Chem 2017 03 1;292(12):4811-4817. Epub 2017 Feb 1.

From the State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China

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http://dx.doi.org/10.1074/jbc.M116.768515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377797PMC
March 2017

BZ-26, a novel GW9662 derivate, attenuated inflammation by inhibiting the differentiation and activation of inflammatory macrophages.

Biomed Pharmacother 2016 Dec 3;84:730-739. Epub 2016 Oct 3.

State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing, 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2016.08.069DOI Listing
December 2016

Herpetol ameliorates allergic contact dermatitis through regulating T-lymphocytes.

Int Immunopharmacol 2016 Nov 31;40:131-138. Epub 2016 Aug 31.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2016.08.025DOI Listing
November 2016

Eriodictyol Inhibits RANKL-Induced Osteoclast Formation and Function Via Inhibition of NFATc1 Activity.

J Cell Physiol 2016 09 2;231(9):1983-93. Epub 2016 Feb 2.

Department of Biochemistry and Molecular Biology, Key Laboratory of Biological Molecular Medicine Research of Guangxi Higher Education, Guangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi, China.

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http://dx.doi.org/10.1002/jcp.25304DOI Listing
September 2016

Roseotoxin B Improves Allergic Contact Dermatitis through a Unique Anti-Inflammatory Mechanism Involving Excessive Activation of Autophagy in Activated T Lymphocytes.

J Invest Dermatol 2016 08 5;136(8):1636-1646. Epub 2016 May 5.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.04.017DOI Listing
August 2016

Activation of PPARγ by a Natural Flavonoid Modulator, Apigenin Ameliorates Obesity-Related Inflammation Via Regulation of Macrophage Polarization.

EBioMedicine 2016 Jul 15;9:61-76. Epub 2016 Jun 15.

State Key Laboratory of Pharmaceutical Biotechnology, School of life Sciences, Nanjing University, Nanjing 210046, China; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing Biomedical Research Institute, Nanjing University, Nanjing 210046, China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972579PMC
July 2016

ε-globin expression is regulated by SUV4-20h1.

Haematologica 2016 05 22;101(5):e168-72. Epub 2016 Jan 22.

The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, China

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http://dx.doi.org/10.3324/haematol.2015.139980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004379PMC
May 2016

Targeting the PDGF-B/PDGFR-β Interface with Destruxin A5 to Selectively Block PDGF-BB/PDGFR-ββ Signaling and Attenuate Liver Fibrosis.

EBioMedicine 2016 May 4;7:146-56. Epub 2016 Apr 4.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.03.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909612PMC
May 2016

Assessment of the Cytotoxic and Apoptotic Eἀects of Chaetominine in a Human Leukemia Cell Line.

Biomol Ther (Seoul) 2016 Mar;24(2):147-55

Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR China.

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http://dx.doi.org/10.4062/biomolther.2015.093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774495PMC
March 2016

Adsorption characteristics and preparative separation of chaetominine from Aspergillus fumigatus mycelia by macroporous resin.

J Chromatogr B Analyt Technol Biomed Life Sci 2016 Mar 20;1015-1016:135-141. Epub 2016 Feb 20.

Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2016.02.027DOI Listing
March 2016

Apigenin inhibits enterovirus-71 infection by disrupting viral RNA association with trans-acting factors.

PLoS One 2014 16;9(10):e110429. Epub 2014 Oct 16.

Medical School and State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, Jiangsu, China; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110429PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199717PMC
December 2015

A benzenediamine derivative fc-99 attenuates lupus-like syndrome in MRL/lpr mice related to suppression of pDC activation.

Immunol Lett 2015 Dec 3;168(2):355-65. Epub 2015 Nov 3.

The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, PR China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing 210093, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2015.10.017DOI Listing
December 2015

Reciprocal Regulation of ERα and ERβ Stability and Activity by Diptoindonesin G.

Chem Biol 2015 Dec 3;22(12):1608-21. Epub 2015 Dec 3.

McArdle Laboratory for Cancer Research, Wisconsin Institute for Medical Research, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI 53705, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2015.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767166PMC
December 2015

Heterochromatin protein HP1γ promotes colorectal cancer progression and is regulated by miR-30a.

Cancer Res 2015 Nov 2;75(21):4593-604. Epub 2015 Sep 2.

The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3735DOI Listing
November 2015

Natural Germacrane Sesquiterpenes Inhibit Osteoclast Formation, Bone Resorption, RANKL-Induced NF-κB Activation, and IκBα Degradation.

Int J Mol Sci 2015 Nov 5;16(11):26599-607. Epub 2015 Nov 5.

Guangzhou Institute of Traumatic Surgery, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, China.

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http://dx.doi.org/10.3390/ijms161125972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661831PMC
November 2015

Berberine Sulfate Attenuates Osteoclast Differentiation through RANKL Induced NF-κB and NFAT Pathways.

Int J Mol Sci 2015 Nov 13;16(11):27087-96. Epub 2015 Nov 13.

School of Pathology and Laboratory Medicine, the University of Western Australia, Perth, WA 6009, Australia.

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http://dx.doi.org/10.3390/ijms161125998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661856PMC
November 2015

Fumigaclavine C ameliorates dextran sulfate sodium-induced murine experimental colitis via NLRP3 inflammasome inhibition.

J Pharmacol Sci 2015 Oct 19;129(2):101-6. Epub 2015 May 19.

Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Science, Nanjing University, Nanjing 210093, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.jphs.2015.05.003DOI Listing
October 2015

LYAR promotes colorectal cancer cell mobility by activating galectin-1 expression.

Oncotarget 2015 Oct;6(32):32890-901

The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210046, China.

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http://dx.doi.org/10.18632/oncotarget.5335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741737PMC
October 2015

Natural phenolic metabolites from endophytic Aspergillus sp. IFB-YXS with antimicrobial activity.

Bioorg Med Chem Lett 2015 Jul 30;25(13):2698-701. Epub 2015 Apr 30.

Nanjing University, School of Life Sciences, Xianlin Road 163, Nanjing 210023, China.

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http://dx.doi.org/10.1016/j.bmcl.2015.04.044DOI Listing
July 2015

FC-98 regulates TLR9-mediated of CXCL-10 expression in dendritic cells via MAPK and STAT1 signaling pathway.

Biomed Res Int 2014 17;2014:926130. Epub 2014 Feb 17.

The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China ; Jiangsu Key Laboratory of Molecular Medicine, Nanjing 210093, China.

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http://dx.doi.org/10.1155/2014/926130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947834PMC
May 2015

A novel 1,2-benzenediamine derivative FC-99 suppresses TLR3 expression and ameliorates disease symptoms in a mouse model of sepsis.

Br J Pharmacol 2014 Nov 23;171(21):4866-78. Epub 2014 Sep 23.

The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, China.

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http://dx.doi.org/10.1111/bph.12797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294110PMC
November 2014

Trichomide A, a natural cyclodepsipeptide, exerts immunosuppressive activity against activated T lymphocytes by upregulating SHP2 activation to overcome contact dermatitis.

J Invest Dermatol 2014 Nov 16;134(11):2737-2746. Epub 2014 Jun 16.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.252DOI Listing
November 2014

A novel small-molecule compound diaporine A inhibits non-small cell lung cancer growth by regulating miR-99a/mTOR signaling.

Cancer Biol Ther 2014 Oct 21;15(10):1423-30. Epub 2014 Jul 21.

The State Key Laboratory of Pharmaceutical Biotechnology; Division of Immunology; Medical School; Nanjing University; Nanjing, PR China; Jiangsu Key Laboratory of Molecular Medicine; Nanjing, PR China.

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http://dx.doi.org/10.4161/cbt.29925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130735PMC
October 2014

Novel benzenediamine derivative FC99 ameliorates zymosan-induced arthritis by inhibiting RORγt expression and Th17 cell differentiation.

Acta Biochim Biophys Sin (Shanghai) 2014 Oct 3;46(10):829-36. Epub 2014 Sep 3.

The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China Jiangsu Key Laboratory of Molecular Medicine, Nanjing 210093, China

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http://dx.doi.org/10.1093/abbs/gmu074DOI Listing
October 2014

TL-2 attenuates β-amyloid induced neuronal apoptosis through the AKT/GSK-3β/β-catenin pathway.

Int J Neuropsychopharmacol 2014 Sep 19;17(9):1511-9. Epub 2014 Mar 19.

Department of Neurology,Affiliated Drum Tower Hospital of Nanjing University Medical School,Nanjing,PR China.

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http://dx.doi.org/10.1017/S1461145714000315DOI Listing
September 2014

Human fetal globin gene expression is regulated by LYAR.

Nucleic Acids Res 2014 Sep 4;42(15):9740-52. Epub 2014 Aug 4.

The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China

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http://dx.doi.org/10.1093/nar/gku718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150809PMC
September 2014

A novel benzenediamine derivate rescued mice from experimental sepsis by attenuating proinflammatory mediators via IRAK4.

Am J Respir Cell Mol Biol 2014 Aug;51(2):191-200

1 The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School.

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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2013-0411OC
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http://dx.doi.org/10.1165/rcmb.2013-0411OCDOI Listing
August 2014

Requirement of PEA3 for transcriptional activation of FAK gene in tumor metastasis.

PLoS One 2013 18;8(11):e79336. Epub 2013 Nov 18.

The State Key Laboratory of Pharmaceutical Biotechnology, College of Life Science and School of Stomatology, Affiliated Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079336PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832605PMC
July 2014

Dalesconols B inhibits lipopolysaccharide induced inflammation and suppresses NF-κB and p38/JNK activation in microglial cells.

Neurochem Int 2013 Jun 15;62(7):913-21. Epub 2013 Mar 15.

Department of Neurology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu 210008, PR China.

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http://dx.doi.org/10.1016/j.neuint.2013.03.003DOI Listing
June 2013

Mechanisms of CpG-induced CD40 expression on murine bone marrow-derived dendritic cells.

Autoimmunity 2013 May 7;46(3):177-87. Epub 2013 Feb 7.

School of Medicine, Nanjing University, Immunology and Reproductive Biology Lab & Jiangsu Key Laboratory of Molecular Medicine, Nanjing, China.

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http://dx.doi.org/10.3109/08916934.2012.751980DOI Listing
May 2013

A novel benzo[d]imidazole derivate prevents the development of dextran sulfate sodium-induced murine experimental colitis via inhibition of NLRP3 inflammasome.

Biochem Pharmacol 2013 May 15;85(10):1504-12. Epub 2013 Mar 15.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.

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https://linkinghub.elsevier.com/retrieve/pii/S00062952130018
Publisher Site
http://dx.doi.org/10.1016/j.bcp.2013.03.008DOI Listing
May 2013

Bis-N-norgliovictin, a small-molecule compound from marine fungus, inhibits LPS-induced inflammation in macrophages and improves survival in sepsis.

Eur J Pharmacol 2013 Apr 22;705(1-3):49-60. Epub 2013 Feb 22.

Immunology and Reproductive Biology Lab & Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, Nanjing 210093, PR China.

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http://dx.doi.org/10.1016/j.ejphar.2013.02.008DOI Listing
April 2013

Chaetoglobosin F, a small molecule compound, possesses immunomodulatory properties on bone marrow-derived dendritic cells via TLR9 signaling pathway.

Immunobiology 2013 Mar 23;218(3):292-302. Epub 2012 May 23.

Immunology and Reproductive Biology Lab & Jiangsu Key Laboratory of Molecular Medicine, School of Medicine, Nanjing University, Nanjing 210093, PR China.

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http://dx.doi.org/10.1016/j.imbio.2012.05.015DOI Listing
March 2013

Hopeahainol A attenuates memory deficits by targeting β-amyloid in APP/PS1 transgenic mice.

Aging Cell 2013 Feb 21;12(1):85-92. Epub 2012 Nov 21.

Department of Neurology, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China.

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http://doi.wiley.com/10.1111/acel.12022
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http://dx.doi.org/10.1111/acel.12022DOI Listing
February 2013

Induction of human fetal hemoglobin expression by adenosine-2',3'-dialdehyde.

J Transl Med 2013 Jan 14;11:14. Epub 2013 Jan 14.

Molecular Immunology and Cancer Research Center, The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210093, China.

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http://dx.doi.org/10.1186/1479-5876-11-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599103PMC
January 2013

Oestrogen attenuates tumour progression in hepatocellular carcinoma.

J Pathol 2012 Oct 2;228(2):216-29. Epub 2012 May 2.

State Key Laboratory of Pharmaceutical Biotechnology and Model Animal Research Center, Nanjing University, Nanjing, China.

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http://dx.doi.org/10.1002/path.4009DOI Listing
October 2012

A small molecule IFB07188 inhibits proliferation of human cancer cells by inducing G2/M cell cycle arrest and apoptosis.

Biomed Pharmacother 2012 Oct 19;66(7):512-8. Epub 2012 Jun 19.

State Key Laboratory of Pharmaceutical Biotechnology and Model Animal Research Center, Nanjing University, Nanjing, China.

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http://dx.doi.org/10.1016/j.biopha.2012.05.003DOI Listing
October 2012

Selective sequestration of STAT1 in the cytoplasm via phosphorylated SHP-2 ameliorates murine experimental colitis.

J Immunol 2012 Oct 31;189(7):3497-507. Epub 2012 Aug 31.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China.

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http://dx.doi.org/10.4049/jimmunol.1201006DOI Listing
October 2012

Chaeoglobosin Fex inhibits poly(I:C)-induced activation of bone marrow-derived dendritic cells.

Mol Immunol 2012 Jun 17;51(2):150-8. Epub 2012 Mar 17.

Immunology and Reproductive Biology Lab & Jiangsu Key Laboratory of Molecular Medicine, School of Medicine, Nanjing University, Nanjing 210093, PR China.

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http://dx.doi.org/10.1016/j.molimm.2012.02.125DOI Listing
June 2012

Chaetoglobosin Fex from the marine-derived endophytic fungus inhibits induction of inflammatory mediators via Toll-like receptor 4 signaling in macrophages.

Biol Pharm Bull 2011 ;34(12):1864-73

Immunology and Reproductive Biology Lab & Jiangsu Key Laboratory of Molecular Medicine, School of Medicine, Nanjing University, Nanjing 210093, P. R. China.

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http://dx.doi.org/10.1248/bpb.34.1864DOI Listing
March 2012

Organocatalytic enantioselective amination of Morita-Baylis-Hillman carbonates with masked ammonia: a facile method for the synthesis of unprotected α-methylene-β-amino esters.

Chemistry 2011 Dec 3;17(49):13676-9. Epub 2011 Nov 3.

School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, China.

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http://dx.doi.org/10.1002/chem.201102522DOI Listing
December 2011

Organocatalytic asymmetric Michael-type/Wittig reaction of phosphorus ylides: synthesis of chiral α-methylene-δ-ketoesters.

Org Lett 2011 Aug 14;13(16):4176-9. Epub 2011 Jul 14.

School of Chemistry and Chemical Engineering, State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing, 210093, China.

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http://pubs.acs.org/doi/abs/10.1021/ol201483s
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http://dx.doi.org/10.1021/ol201483sDOI Listing
August 2011

Tectorigenin inhibits the in vitro proliferation and enhances miR-338* expression of pulmonary fibroblasts in rats with idiopathic pulmonary fibrosis.

J Ethnopharmacol 2010 Aug 19;131(1):165-73. Epub 2010 Jun 19.

Department of Medical Genetics, Nanjing University School of Medicine, Nanjing, China.

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http://dx.doi.org/10.1016/j.jep.2010.06.022DOI Listing
August 2010

Redox imbalance provokes deactivation of macrophages in sepsis.

Proteomics Clin Appl 2009 Aug 30;3(8):1000-9. Epub 2009 Jul 30.

Department of Biochemistry, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, P. R. China.

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http://dx.doi.org/10.1002/prca.200800016DOI Listing
August 2009

Tn5 transposase-assisted high-efficiency transformation of filamentous fungus Phoma herbarum YS4108.

Appl Microbiol Biotechnol 2008 Oct 21;80(5):937-44. Epub 2008 Aug 21.

Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Medical School, Nanjing University, Nanjing, People's Republic of China.

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http://dx.doi.org/10.1007/s00253-008-1615-yDOI Listing
October 2008

Total flavonoids of Daphne genkwa root significantly inhibit the growth and metastasis of Lewis lung carcinoma in C57BL6 mice.

Int Immunopharmacol 2007 Feb 4;7(2):117-27. Epub 2006 Aug 4.

Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, Xuzhou Normal University, Xuzhou, China.

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http://dx.doi.org/10.1016/j.intimp.2006.07.010DOI Listing
February 2007

Fabrication and properties of a porous chitin/chitosan conduit for nerve regeneration.

Biotechnol Lett 2004 Dec;26(23):1793-7

Institute of Functional Biomolecules, State Key Laboratory for Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, PR China.

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http://dx.doi.org/10.1007/s10529-004-4611-zDOI Listing
December 2004

Fumigaclavine C improves concanavalin A-induced liver injury in mice mainly via inhibiting TNF-alpha production and lymphocyte adhesion to extracellular matrices.

J Pharm Pharmacol 2004 Jun;56(6):775-82

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China.

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http://dx.doi.org/10.1211/0022357023592DOI Listing
June 2004