Rentian Feng

Rentian Feng

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Rentian Feng

Rentian Feng

Publications by authors named "Rentian Feng"

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Multifunctional Compound AD-35 Improves Cognitive Impairment and Attenuates the Production of TNF-α and IL-1β in an Aβ25-35-induced Rat Model of Alzheimer's Disease.

J Alzheimers Dis 2017 ;56(4):1403-1417

State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.3233/JAD-160587DOI Listing
February 2018

Targeting cannabinoid receptor-2 pathway by phenylacetylamide suppresses the proliferation of human myeloma cells through mitotic dysregulation and cytoskeleton disruption.

Mol Carcinog 2015 Dec 16;54(12):1796-806. Epub 2015 Jan 16.

Department of Pharmaceutical Sciences and Drug Discovery Institute, Computational Chemical Genomics Screening Center, School of Pharmacy, and NIH NIDA Center of Excellence for Computational Drug Abuse Research, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/mc.22251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504841PMC
December 2015

Examining the critical roles of human CB2 receptor residues Valine 3.32 (113) and Leucine 5.41 (192) in ligand recognition and downstream signaling activities.

Biochem Biophys Res Commun 2014 Sep 19;452(3):334-9. Epub 2014 Aug 19.

Department of Pharmaceutical Sciences and Computational Chemical Genomics Screening Center, School of Pharmacy, Pittsburgh, PA 15260, USA; Joint Carnegie Mellon University-University of Pittsburgh Ph.D. Program, Department of Computational Biology and Structural Biology, School of Medicine, Pittsburgh, PA 15260, USA; Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA 15260, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.08.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465889PMC
September 2014

Antagonism of cannabinoid receptor 2 pathway suppresses IL-6-induced immunoglobulin IgM secretion.

BMC Pharmacol Toxicol 2014 Jun 9;15:30. Epub 2014 Jun 9.

Department of Pharmaceutical Sciences, Computational Chemical Genomics Screening Center, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1186/2050-6511-15-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062519PMC
June 2014

Trisubstituted Sulfonamides: a New Chemotype for Development of Potent and Selective CB Receptor Inverse Agonists.

ACS Med Chem Lett 2013 Apr;4(4):387-392

Department of Pharmaceutical Sciences and Computational Chemical Genomics Screening Center, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA ; Drug Discovery Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA ; Pittsburgh Chemical Methods and Library Development Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA ; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA ; Department of Structural Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

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http://dx.doi.org/10.1021/ml3004236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979583PMC
April 2013

Novel triaryl sulfonamide derivatives as selective cannabinoid receptor 2 inverse agonists and osteoclast inhibitors: discovery, optimization, and biological evaluation.

J Med Chem 2013 Mar 1;56(5):2045-58. Epub 2013 Mar 1.

Department of Pharmaceutical Sciences and Computational Chemical Genomics Screening Center, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.

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http://pubs.acs.org/doi/10.1021/jm3017464
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http://dx.doi.org/10.1021/jm3017464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967766PMC
March 2013

Mistic and TarCF as fusion protein partners for functional expression of the cannabinoid receptor 2 in Escherichia coli.

Protein Expr Purif 2012 Jun 3;83(2):128-34. Epub 2012 Mar 3.

Department of Pharmaceutical Sciences, School of Pharmacy, and Computational Chemical Genomics Screening Center, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1016/j.pep.2012.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967764PMC
June 2012

Apaf-1 deficiency confers resistance to ultraviolet-induced apoptosis in mouse embryonic fibroblasts by disrupting reactive oxygen species amplification production and mitochondrial pathway.

Free Radic Biol Med 2012 Mar 21;52(5):889-97. Epub 2011 Dec 21.

Department of Pathology, Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2011.11.028DOI Listing
March 2012

Targeting the microtubular network as a new antimyeloma strategy.

Mol Cancer Ther 2011 Oct 8;10(10):1886-96. Epub 2011 Aug 8.

Division of Hematology/Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0234DOI Listing
October 2011

Cell-based and cytokine-directed chemical screen to identify potential anti-multiple myeloma agents.

Leuk Res 2010 Jul 8;34(7):917-24. Epub 2010 Feb 8.

Department of Medicine, Division of Hematology and Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1016/j.leukres.2009.12.002DOI Listing
July 2010

Delphinidin induces necrosis in hepatocellular carcinoma cells in the presence of 3-methyladenine, an autophagy inhibitor.

J Agric Food Chem 2010 Apr;58(7):3957-64

Department of Pathology and Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1021/jf9025458DOI Listing
April 2010

KD5170, a novel mercaptoketone-based histone deacetylase inhibitor, exerts antimyeloma effects by DNA damage and mitochondrial signaling.

Mol Cancer Ther 2008 Jun;7(6):1494-505

Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh Cancer Institute, 5150 Centre Avenue, 568, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-08-0183DOI Listing
June 2008

The histone deacetylase inhibitor, PXD101, potentiates bortezomib-induced anti-multiple myeloma effect by induction of oxidative stress and DNA damage.

Br J Haematol 2007 Nov;139(3):385-97

Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2007.06772.xDOI Listing
November 2007

Treatment of multiple myeloma with SDX-308.

Drug News Perspect 2007 Sep;20(7):431-5

Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15232, USA.

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http://dx.doi.org/10.1358/dnp.2007.20.7.1149631DOI Listing
September 2007

Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress.

J Biol Chem 2007 May 14;282(18):13468-76. Epub 2007 Mar 14.

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1074/jbc.M610616200DOI Listing
May 2007

Antioxidant activity of Vaccinium stamineum: exhibition of anticancer capability in human lung and leukemia cells.

Planta Med 2007 May 29;73(5):451-60. Epub 2007 Mar 29.

Fruit Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, U. S. Department of Agriculture, Beltsville, MD 20705-2350, USA.

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http://dx.doi.org/10.1055/s-2007-967164DOI Listing
May 2007

Ozone exposure impairs antigen-specific immunity but activates IL-7-induced proliferation of CD4-CD8- thymocytes in BALB/c mice.

J Toxicol Environ Health A 2006 Aug;69(16):1511-26

Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1080/15287390500468696DOI Listing
August 2006

Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity.

J Biol Chem 2006 Jun 17;281(25):17359-68. Epub 2006 Apr 17.

Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA.

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http://dx.doi.org/10.1074/jbc.M600861200DOI Listing
June 2006

Inhibition of activator protein-1, NF-kappaB, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid.

J Biol Chem 2005 Jul 8;280(30):27888-95. Epub 2005 Jun 8.

Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M503347200
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http://dx.doi.org/10.1074/jbc.M503347200DOI Listing
July 2005

Inhibitory effect on activator protein-1, nuclear factor-kappaB, and cell transformation by extracts of strawberries (Fragaria x ananassa Duch.).

J Agric Food Chem 2005 May;53(10):4187-93

Fruit Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, Maryland 20705-2350, USA.

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http://dx.doi.org/10.1021/jf0478049DOI Listing
May 2005

Blackberry extracts inhibit activating protein 1 activation and cell transformation by perturbing the mitogenic signaling pathway.

Nutr Cancer 2004 ;50(1):80-9

Pathology and Physiology Research Branch, Helath Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.

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http://www.tandfonline.com/doi/abs/10.1207/s15327914nc5001_1
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http://dx.doi.org/10.1207/s15327914nc5001_11DOI Listing
April 2005

Antioxidant activity in lingonberries (Vaccinium vitis-idaea L.) and its inhibitory effect on activator protein-1, nuclear factor-kappaB, and mitogen-activated protein kinases activation.

J Agric Food Chem 2005 Apr;53(8):3156-66

Fruit Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, Maryland 20705-2350, USA.

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http://dx.doi.org/10.1021/jf048379mDOI Listing
April 2005