Publications by authors named "Rene Raphemot"

16 Publications

  • Page 1 of 1

Discovery of Druggable Host Factors Critical to Plasmodium Liver-Stage Infection.

Cell Chem Biol 2019 09 27;26(9):1253-1262.e5. Epub 2019 Jun 27.

Department of Chemistry, Duke University, 124 Science Drive, Durham, NC 27708, USA; Department of Molecular Genetics and Microbiology, Duke University Medical Center, 213 Research Drive, Durham, NC 27710, USA. Electronic address:

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September 2019

Plasmodium PK9 Inhibitors Promote Growth of Liver-Stage Parasites.

Cell Chem Biol 2019 03 27;26(3):411-419.e7. Epub 2018 Dec 27.

Department of Chemistry, Duke University, 124 Science Drive, Durham, NC 27708, USA; Department of Molecular Genetics and Microbiology, Duke University Medical Center, 213 Research Drive, Durham, NC 27710, USA. Electronic address:

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March 2019

Discovery of Dual-Stage Malaria Inhibitors with New Targets.

Antimicrob Agents Chemother 2015 Dec 14;60(3):1430-7. Epub 2015 Dec 14.

Department of Chemistry, Duke University, Durham, North Carolina, USA Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA

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December 2015

Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels.

PLoS One 2014 6;9(11):e110772. Epub 2014 Nov 6.

Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, United States of America; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, United States of America; Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, TN, United States of America; Institute for Global Health, Vanderbilt University, Nashville, TN, United States of America.

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July 2015

Excretion of NaCl and KCl loads in mosquitoes. 2. Effects of the small molecule Kir channel modulator VU573 and its inactive analog VU342.

Am J Physiol Regul Integr Comp Physiol 2014 Oct 23;307(7):R850-61. Epub 2014 Jul 23.

Department of Biomedical Sciences, Cornell University, Ithaca, New York; and

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October 2014

Pharmacological validation of an inward-rectifier potassium (Kir) channel as an insecticide target in the yellow fever mosquito Aedes aegypti.

PLoS One 2014 24;9(6):e100700. Epub 2014 Jun 24.

Department of Entomology, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio, United States of America.

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March 2015

Molecular and functional characterization of Anopheles gambiae inward rectifier potassium (Kir1) channels: a novel role in egg production.

Insect Biochem Mol Biol 2014 Aug 20;51:10-9. Epub 2014 May 20.

Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA; Institute for Global Health, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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August 2014

Direct activation of β-cell KATP channels with a novel xanthine derivative.

Mol Pharmacol 2014 Jun 19;85(6):858-65. Epub 2014 Mar 19.

Departments of Anesthesiology (R.R., D.R.S., S.B., J.S.D.), Pharmacology (R.R., J.S.D.), and Molecular Physiology and Biophysics (P.K.D., D.A.J.) and Institutes of Chemical Biology (J.S.D.) and Global Health (J.S.D.), Vanderbilt University Medical Center, Nashville, Tennessee; Department of Medicine, University of Rochester Medical Center, Rochester, New York (A.P.W.); and Department of Cell Biology and Physiology (P.C., C.G.N.) and Center for the Investigation of Membrane Excitability Disorders (P.C., C.G.N.), Washington University School of Medicine in St. Louis, St. Louis, Missouri.

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June 2014

High-throughput screening for small-molecule modulators of inward rectifier potassium channels.

J Vis Exp 2013 Jan 27(71). Epub 2013 Jan 27.

Department of Pharmacology, Vanderbilt University School of Medicine, USA.

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January 2013