Renaud Dumas

Laboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives/Biosciences and Biotechnology Institute of Grenoble, Institut National de la Recherche Agronomique (INRA), F-38000 Grenoble, France.

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July 2017

Plant SAM-Domain Proteins Start to Reveal Their Roles.

Authors:

Grégoire Denay Gilles Vachon Renaud Dumas Chloe Zubieta François Parcy

Trends Plant Sci 2017 08 28;22(8):718-725. Epub 2017 Jun 28.

LPCV, CEA, CNRS, INRA, Université Grenoble-Alpes, BIG, 38000 Grenoble, France. Electronic address:

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August 2017

A link between LEAFY and B-gene homologues in Welwitschia mirabilis sheds light on ancestral mechanisms prefiguring floral development.

Authors:

Edwige Moyroud Marie Monniaux Emmanuel Thévenon Renaud Dumas Charles P Scutt Michael W Frohlich François Parcy

New Phytol 2017 Oct 24;216(2):469-481. Epub 2017 Feb 24.

LPCV, CEA, CNRS, INRA, Université Grenoble-Alpes, BIG, 38000, Grenoble, France.

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October 2017

Crystal structure of norcoclaurine-6-O-methyltransferase, a key rate-limiting step in the synthesis of benzylisoquinoline alkaloids.

Authors:

Adeline Y Robin Cécile Giustini Matthieu Graindorge Michel Matringe Renaud Dumas

Plant J 2016 09 6;87(6):641-53. Epub 2016 Aug 6.

Laboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS UMR5168, CEA/DRF/BIG, INRA UMR 1417, 17, Avenue des Martyrs, 38054 Grenoble, France.

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September 2016

A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor.

Authors:

Camille Sayou Max H Nanao Marc Jamin David Posé Emmanuel Thévenon Laura Grégoire Gabrielle Tichtinsky Grégoire Denay Felix Ott Marta Peirats Llobet Markus Schmid Renaud Dumas François Parcy

Nat Commun 2016 Apr 21;7:11222. Epub 2016 Apr 21.

Laboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS UMR5168, CEA/DRF/BIG, INRA UMR 1417, 17, avenue des Martyrs, 38054 Grenoble, France.

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April 2016

A Glimpse beyond Structures in Auxin-Dependent Transcription.

Authors:

François Parcy Teva Vernoux Renaud Dumas

Trends Plant Sci 2016 07 22;21(7):574-583. Epub 2016 Mar 22.

Laboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS UMR5168, CEA/DRF/BIG, INRA UMR 1417, Grenoble, France.

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July 2016

The Myb-domain protein ULTRAPETALA1 INTERACTING FACTOR 1 controls floral meristem activities in Arabidopsis.

Authors:

Fanny Moreau Emmanuel Thévenon Robert Blanvillain Irene Lopez-Vidriero Jose Manuel Franco-Zorrilla Renaud Dumas François Parcy Patrice Morel Christophe Trehin Cristel C Carles

Development 2016 Apr 22;143(7):1108-19. Epub 2016 Feb 22.

Université Grenoble Alpes, Laboratoire de Physiologie Cellulaire et Végétale (LPCV), Grenoble 38054, France CNRS, LPCV, UMR 5168, Grenoble 38054, France CEA, Direction des Sciences du Vivant, BIG, LPCV, Grenoble 38054, France INRA, LPCV, Grenoble 38054, France

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April 2016

Evolution. Response to Comment on "A promiscuous intermediate underlies the evolution of LEAFY DNA binding specificity".

Authors:

Samuel F Brockington Edwige Moyroud Camille Sayou Marie Monniaux Max H Nanao Emmanuel Thévenon Hicham Chahtane Norman Warthmann Michael Melkonian Yong Zhang Gane Ka-Shu Wong Detlef Weigel Renaud Dumas François Parcy

Science 2015 Feb;347(6222):621

CNRS, Laboratoire de Physiologie Cellulaire et Végétale (LPCV), UMR 5168, 38054 Grenoble, France. UGA, LPCV, F-38054 Grenoble, France. Commissariat à l'énergie atomique et aux énergies alternatives, Direction des Sciences du Vivant, Institut de Recherches en Technologies et Sciences pour le Vivant, LPCV, F-38054 Grenoble, France. Institut National de la Recherche Agronomique, LPCV, F-38054 Grenoble, France.

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February 2015

Biochemical and biophysical characterization of the selenium-binding and reducing site in Arabidopsis thaliana homologue to mammals selenium-binding protein 1.

Authors:

Florie Schild Sylvie Kieffer-Jaquinod Andrés Palencia David Cobessi Géraldine Sarret Chloé Zubieta Agnès Jourdain Renaud Dumas Vincent Forge Denis Testemale Jacques Bourguignon Véronique Hugouvieux

J Biol Chem 2014 Nov 1;289(46):31765-76. Epub 2014 Oct 1.

From the Institut de Recherches en Technologies et Sciences pour le Vivant, Laboratoire de Physiologie Cellulaire et Végétale, CEA, Université Grenoble Alpes, CNRS UMR5168, INRA USC1359,

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November 2014

Structural basis for the oligomerization of the MADS domain transcription factor SEPALLATA3 in Arabidopsis.

Authors:

Sriharsha Puranik Samira Acajjaoui Simon Conn Luca Costa Vanessa Conn Anthony Vial Romain Marcellin Rainer Melzer Elizabeth Brown Darren Hart Günter Theißen Catarina S Silva François Parcy Renaud Dumas Max Nanao Chloe Zubieta

Plant Cell 2014 Sep 16;26(9):3603-15. Epub 2014 Sep 16.

CNRS, Laboratoire de Physiologie Cellulaire and Végétale, UMR 5168, 38054 Grenoble, France Université Grenoble Alpes, Laboratoire de Physiologie Cellulaire et Végétale, F-38054 Grenoble, France Commissariat à l'Energie Atomique, Direction des Sciences du Vivant, Institut de Recherches en Technologies et Sciences pour le Vivant, Laboratoire de Physiologie Cellulaire et Végétale, F-38054 Grenoble, France INRA, Laboratoire de Physiologie Cellulaire et Végétale, USC1359, F-38054 Grenoble, France

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September 2014

Structural basis for oligomerization of auxin transcriptional regulators.

Authors:

Max H Nanao Thomas Vinos-Poyo Géraldine Brunoud Emmanuel Thévenon Meryl Mazzoleni David Mast Stéphanie Lainé Shucai Wang Gretchen Hagen Hanbing Li Thomas J Guilfoyle François Parcy Teva Vernoux Renaud Dumas

Nat Commun 2014 Apr 7;5:3617. Epub 2014 Apr 7.

1] CNRS, Laboratoire de Physiologie Cellulaire and Végétale, UMR 5168, Grenoble 38054, France [2] Univ. Grenoble Alpes, LPCV, Grenoble F-38054, France [3] CEA, DSV, iRTSV, LPCV, Grenoble F-38054, France [4] INRA, LPCV, Grenoble F-38054, France.

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April 2014

Molecular basis for AUXIN RESPONSE FACTOR protein interaction and the control of auxin response repression.

Authors:

David A Korasick Corey S Westfall Soon Goo Lee Max H Nanao Renaud Dumas Gretchen Hagen Thomas J Guilfoyle Joseph M Jez Lucia C Strader

Proc Natl Acad Sci U S A 2014 Apr 25;111(14):5427-32. Epub 2014 Mar 25.

Department of Biology, Washington University, St. Louis, MO 63130.

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April 2014

A promiscuous intermediate underlies the evolution of LEAFY DNA binding specificity.

Authors:

Camille Sayou Marie Monniaux Max H Nanao Edwige Moyroud Samuel F Brockington Emmanuel Thévenon Hicham Chahtane Norman Warthmann Michael Melkonian Yong Zhang Gane Ka-Shu Wong Detlef Weigel François Parcy Renaud Dumas

Science 2014 Feb 16;343(6171):645-8. Epub 2014 Jan 16.

CNRS, Laboratoire de Physiologie Cellulaire et Végétale (LPCV), UMR 5168, 38054 Grenoble, France.

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February 2014

Cytokinin signalling inhibitory fields provide robustness to phyllotaxis.

Nature 2014 Jan 15;505(7483):417-21. Epub 2013 Dec 15.

Laboratoire de Reproduction et Développement des Plantes, CNRS, INRA, ENS Lyon, UCBL, Université de Lyon, 69364 Lyon, France.

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January 2014

Inhibition of p-aminobenzoate and folate syntheses in plants and apicomplexan parasites by natural product rubreserine.

Authors:

Djeneb Camara Cordelia Bisanz Caroline Barette Jeroen Van Daele Esmare Human Bernice Barnard Dominique Van der Straeten Christophe P Stove Willy E Lambert Roland Douce Eric Maréchal Lyn-Marie Birkholtz Marie-France Cesbron-Delauw Renaud Dumas Fabrice Rébeillé

J Biol Chem 2012 Jun 10;287(26):22367-76. Epub 2012 May 10.

Laboratoire de Physiologie Cellulaire Végétale, Commissariat à l'Energie Atomique/CNRS UMR5168/INRA USC1200/Université Joseph Fourier Grenoble I, Institut de Recherches en Technologies et Sciences pour le Vivant, F-38054 Grenoble, France.

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June 2012

Biochemical and structural characterization of the Arabidopsis bifunctional enzyme dethiobiotin synthetase-diaminopelargonic acid aminotransferase: evidence for substrate channeling in biotin synthesis.

Authors:

David Cobessi Renaud Dumas Virginie Pautre Céline Meinguet Jean-Luc Ferrer Claude Alban

Plant Cell 2012 Apr 30;24(4):1608-25. Epub 2012 Apr 30.

Commissariat à l'Energie Atomique et aux Energies Alternatives, Centre National de la Recherche Scientifique, Université Joseph Fourier, Institut de Biologie Structurale Jean-Pierre Ebel, F-38027 Grenoble Cedex 1, France.

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April 2012

The many faces of aspartate kinases.

Authors:

Renaud Dumas David Cobessi Adeline Y Robin Jean-Luc Ferrer Gilles Curien

Arch Biochem Biophys 2012 Mar 6;519(2):186-93. Epub 2011 Nov 6.

CEA, iRTSV, Laboratoire de Physiologie Cellulaire et Végétale, F-38054 Grenoble, France.

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March 2012

4-hydroxyphenylpyruvate dioxygenase catalysis: identification of catalytic residues and production of a hydroxylated intermediate shared with a structurally unrelated enzyme.

Authors:

Corinne Raspail Matthieu Graindorge Yohann Moreau Serge Crouzy Bertrand Lefèbvre Adeline Y Robin Renaud Dumas Michel Matringe

J Biol Chem 2011 Jul 25;286(29):26061-70. Epub 2011 May 25.

Université Joseph Fourier, France.

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July 2011

The synthesis of pABA: Coupling between the glutamine amidotransferase and aminodeoxychorismate synthase domains of the bifunctional aminodeoxychorismate synthase from Arabidopsis thaliana.

Authors:

Djeneb Camara Céline Richefeu-Contesto Bernadette Gambonnet Renaud Dumas Fabrice Rébeillé

Arch Biochem Biophys 2011 Jan 17;505(1):83-90. Epub 2010 Sep 17.

Laboratoire de Physiologie Cellulaire Végétale, UMR5168 CNRS-CEA-INRA-Université Joseph Fourier Grenoble I, Institut de Recherches en Technologies et Sciences pour le Vivant, CEA-Grenoble, 17 rue des Martyrs, F-38054 Grenoble Cedex 9, France.

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January 2011

A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria.

Authors:

Adeline Y Robin David Cobessi Gilles Curien Mylène Robert-Genthon Jean-Luc Ferrer Renaud Dumas

J Mol Biol 2010 Jun 14;399(2):283-93. Epub 2010 Apr 14.

Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5168, Grenoble, France.

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June 2010

Understanding the regulation of aspartate metabolism using a model based on measured kinetic parameters.

Authors:

Gilles Curien Olivier Bastien Mylène Robert-Genthon Athel Cornish-Bowden María Luz Cárdenas Renaud Dumas

Mol Syst Biol 2009 19;5:271. Epub 2009 May 19.

CNRS, UMR 5168, 17 rue des Martyrs, Grenoble, France.

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July 2009

Amino acid biosynthesis: new architectures in allosteric enzymes.

Authors:

Gilles Curien Valérie Biou Corine Mas-Droux Mylène Robert-Genthon Jean-Luc Ferrer Renaud Dumas

Plant Physiol Biochem 2008 Mar 31;46(3):325-39. Epub 2007 Dec 31.

Laboratoire de Physiologie Cellulaire Végétale, Université Joseph Fourier, Commissariat à l'Energie Atomique, Institut de Recherche et de Technologie des Sciences du Vivant, 38054 Grenoble, France.

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March 2008

Allosteric monofunctional aspartate kinases from Arabidopsis.

Authors:

Gilles Curien Mathieu Laurencin Mylène Robert-Genthon Renaud Dumas

FEBS J 2007 Jan 28;274(1):164-76. Epub 2006 Nov 28.

Laboratoire de Physiologie cellulaire Végétale (PCV-DRDC), CEA-CNRS-INRA-Université Joseph Fourier, Grenoble, France.

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January 2007

A novel organization of ACT domains in allosteric enzymes revealed by the crystal structure of Arabidopsis aspartate kinase.

Authors:

Corine Mas-Droux Gilles Curien Mylène Robert-Genthon Mathieu Laurencin Jean-Luc Ferrer Renaud Dumas

Plant Cell 2006 Jul 26;18(7):1681-92. Epub 2006 May 26.

Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Université Joseph Fourier, Commissariat à l'Energie Atomique, Département Réponse et Dynamique Cellulaires, France.

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July 2006

Biochemical characterization and crystal structure of Synechocystis arogenate dehydrogenase provide insights into catalytic reaction.

Authors:

Pierre Legrand Renaud Dumas Marlene Seux Pascal Rippert Raimond Ravelli Jean-Luc Ferrer Michel Matringe

Structure 2006 Apr;14(4):767-76

Institut de Biologie Structurale Jean-Pierre Ebel, Centre National de la Recherche Scientifique, Université Joseph Fourier, Laboratoire de Cristallographie et Cristallogenèse des Protéines/Groupe Synchrotron, 38027 Grenoble cedex 1, France.

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April 2006

Allosteric threonine synthase. Reorganization of the pyridoxal phosphate site upon asymmetric activation through S-adenosylmethionine binding to a novel site.

Authors:

Corine Mas-Droux Valérie Biou Renaud Dumas

J Biol Chem 2006 Feb 29;281(8):5188-96. Epub 2005 Nov 29.

Laboratoire de Physiologie Cellulaire Végétale, Département Réponse et Dynamique Cellulaires, CNRS Commissariat à l'Energie Atomique, 38054 Grenoble, France.

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February 2006

Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity.

Authors:

Gilles Curien Stéphane Ravanel Mylène Robert Renaud Dumas

J Biol Chem 2005 Dec 10;280(50):41178-83. Epub 2005 Oct 10.

Laboratoire de Physiologie Cellulaire Végétale UMR5168, CEA-CNRS-INRA-Université Joseph Fourier, 38054 Grenoble, France.

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December 2005

Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate.

Authors:

Jean-Luc Ferrer Stéphane Ravanel Mylène Robert Renaud Dumas

J Biol Chem 2004 Oct 23;279(43):44235-8. Epub 2004 Aug 23.

Laboratoire de Cristallogenèse et Cristallographie des Protéines, Institut de Biologie Structurale J.-P. Ebel, 41 rue Jules Horowitz, 38027 Grenoble 1, France.

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October 2004

A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana.

Authors:

Gilles Curien Stéphane Ravanel Renaud Dumas

Eur J Biochem 2003 Dec;270(23):4615-27

Laboratoire de Physiologie Cellulaire Végétale DRDC/CEA-Grenoble, France.

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December 2003

Mechanism of control of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase by threonine.

Authors:

Stéphane Paris Claire Viemon Gilles Curien Renaud Dumas

J Biol Chem 2003 Feb 14;278(7):5361-6. Epub 2002 Nov 14.

Unité Mixte de Recherche 1932, Laboratoire Mixte CNRS/Institut National de la Recherche Agronomique/Bayer Cropscience, 14-20 Rue Pierre Baizet, 69263 Lyon, France.

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February 2003